HU174373B - Sposob poluchenija 1-nitro-9-/omega-/zamehhjonnyj amino/-alkil-amino/-akridinov i ikh solej - Google Patents

Sposob poluchenija 1-nitro-9-/omega-/zamehhjonnyj amino/-alkil-amino/-akridinov i ikh solej

Info

Publication number
HU174373B
HU174373B HU77PO631A HUPO000631A HU174373B HU 174373 B HU174373 B HU 174373B HU 77PO631 A HU77PO631 A HU 77PO631A HU PO000631 A HUPO000631 A HU PO000631A HU 174373 B HU174373 B HU 174373B
Authority
HU
Hungary
Prior art keywords
acridines
omega
alkylamino
nitro
salts
Prior art date
Application number
HU77PO631A
Other languages
English (en)
Inventor
Andrzej Ledochowski
Jerzy Gieldanowski
Czeslaw Radzikowski
Barbara Horowska
Cecylia Kwasniewska-Rokicynska
Barbara Wysocka-Skrzela
Lucyna Sawinska
Mieczyslaw Medon
Original Assignee
Politechnika Gdanska
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Politechnika Gdanska filed Critical Politechnika Gdanska
Publication of HU174373B publication Critical patent/HU174373B/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D219/00—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems
    • C07D219/04—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
    • C07D219/08—Nitrogen atoms
    • C07D219/10—Nitrogen atoms attached in position 9
    • C07D219/12—Amino-alkylamino radicals attached in position 9
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
HU77PO631A 1976-02-25 1977-02-25 Sposob poluchenija 1-nitro-9-/omega-/zamehhjonnyj amino/-alkil-amino/-akridinov i ikh solej HU174373B (hu)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PL1976187520A PL106752B1 (pl) 1976-02-25 1976-02-25 Sposob otrzymywania nowych 1-nitro-9-alkiloaminoalkiloaminoakrydyn lub ich soli

Publications (1)

Publication Number Publication Date
HU174373B true HU174373B (hu) 1979-12-28

Family

ID=19975777

Family Applications (1)

Application Number Title Priority Date Filing Date
HU77PO631A HU174373B (hu) 1976-02-25 1977-02-25 Sposob poluchenija 1-nitro-9-/omega-/zamehhjonnyj amino/-alkil-amino/-akridinov i ikh solej

Country Status (12)

Country Link
US (1) US4139531A (hu)
JP (1) JPS52102282A (hu)
BE (1) BE851846A (hu)
CH (1) CH630901A5 (hu)
DE (1) DE2707831C2 (hu)
FR (1) FR2342066A1 (hu)
GB (1) GB1528723A (hu)
HU (1) HU174373B (hu)
NL (1) NL7701810A (hu)
PL (1) PL106752B1 (hu)
SE (1) SE435504B (hu)
SU (2) SU719498A3 (hu)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4335244A (en) * 1979-11-30 1982-06-15 Bristol-Myers Company Monolactate salts of 4'-(9-acridinylamino)methanesulfon-m-anisidide
PL126407B1 (en) * 1980-04-23 1983-07-30 Politechnika Gdanska Process for preparing 1-nitro-9-hydroxyalkylaminoacridines or their salts
HU186383B (en) * 1981-02-27 1985-07-29 Biogal Gyogyszergyar Process for producing new citostatic amni-acridie-alpha, beta-bracket-d-bracket closed, or aracket-l-bracket closed-n-glycoside derivatives and salts
JPS57183452U (hu) * 1981-05-12 1982-11-20
US4555572A (en) * 1983-07-19 1985-11-26 Warner-Lambert Company Pyrazolo[3,4,5-kl]acridine compositions and methods for their production and use
US4621086A (en) * 1983-07-19 1986-11-04 Warner-Lambert Company Method of treating leukemia with pyrazolo[3,4,5-kl]acridines
US4588730A (en) * 1984-06-15 1986-05-13 Warner-Lambert Company Pyrazolo[3,4,5-k1]acridine compositions and methods for their use as antimicrobials
EP1484060A3 (en) * 1998-12-02 2005-02-09 Pfizer Products Inc. Methods and compositions for restoring conformational stability of a protein of the p53 family
AU2001238470A1 (en) * 2000-02-18 2001-08-27 New York Medical College 9-alkylamino-1-nitroacridine derivatives
AU2001238499A1 (en) 2000-02-18 2001-08-27 New York Medical College Nitroacridine/tumor inhibitor compositions
US6589961B2 (en) 2000-02-18 2003-07-08 New York Medical College 9-alkylamino-1-nitroacridine derivatives
FR2807039A1 (fr) * 2000-03-31 2001-10-05 Adir NOUVEAU PROCEDE DE PREPARATION DE LA 11-AMINO-3-CHLORO-6,11- DIHYDRO-5,5-DIOXO-6-METHYL-DIBENZO[c,f][1,2]-THIAZEPINE ET APPLICATION A LA SYNTHESE DE LA TIANEPTINE
EP3070078B1 (en) * 2015-03-20 2017-10-04 Politechnika Gdanska Asymmetric bis-acridines with antitumor activity and use thereof

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1962277A (en) * 1927-01-11 1934-06-12 Winthrop Chem Co Inc Basic nitroderivatives of 9-aminoacridines and process for preparing the same
DE1620473C3 (de) 1964-05-25 1980-03-20 Starogardzkie Zaklady Farmaceutyczne Polfa Przedsiebiorstwo Panstwowe, Starogard Gdanski (Polen) Verfahren zur Herstellung von 1 -Nitro-9-(3'-dimethylaminopropylamino)-acridin-dihydrochlorid
US3897435A (en) * 1968-08-31 1975-07-29 Starogadzkie Zaklady Farmaceut N-oxides of 1 -nitro-9-dialkylaminoalkylamino/acridine
CH517096A (de) * 1968-08-31 1971-12-31 Starogardzkie Zakl Farma Verfahren zur Herstellung neuer, biologisch aktiver 1-Nitro-9-(dialkyl-aminoalkylamino)-akridin-N10-oxide

Also Published As

Publication number Publication date
SE7702052L (sv) 1977-08-26
GB1528723A (en) 1978-10-18
DE2707831C2 (de) 1983-02-03
CH630901A5 (de) 1982-07-15
DE2707831A1 (de) 1977-09-01
JPS52102282A (en) 1977-08-27
NL7701810A (nl) 1977-08-29
PL187520A1 (en) 1978-11-06
FR2342066A1 (fr) 1977-09-23
FR2342066B1 (hu) 1979-07-20
SU719498A3 (ru) 1980-02-29
SE435504B (sv) 1984-10-01
PL106752B1 (pl) 1980-01-31
US4139531A (en) 1979-02-13
JPS556630B2 (hu) 1980-02-18
SU718009A3 (ru) 1980-02-25
BE851846A (fr) 1977-06-16

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