HRP20230508T1 - Pripravak koji sadrži ekstrakte peludi i/ili tučka, postupak pripreme i povezane upotrebe - Google Patents
Pripravak koji sadrži ekstrakte peludi i/ili tučka, postupak pripreme i povezane upotrebe Download PDFInfo
- Publication number
- HRP20230508T1 HRP20230508T1 HRP20230508TT HRP20230508T HRP20230508T1 HR P20230508 T1 HRP20230508 T1 HR P20230508T1 HR P20230508T T HRP20230508T T HR P20230508TT HR P20230508 T HRP20230508 T HR P20230508T HR P20230508 T1 HRP20230508 T1 HR P20230508T1
- Authority
- HR
- Croatia
- Prior art keywords
- pollen
- extract
- extracts
- preparation
- pistil
- Prior art date
Links
- 239000000284 extract Substances 0.000 title claims 22
- 238000002360 preparation method Methods 0.000 title claims 13
- 239000000203 mixture Substances 0.000 title claims 3
- 240000008042 Zea mays Species 0.000 claims 5
- 241000196324 Embryophyta Species 0.000 claims 4
- 235000007238 Secale cereale Nutrition 0.000 claims 4
- 235000007244 Zea mays Nutrition 0.000 claims 4
- 238000000605 extraction Methods 0.000 claims 4
- 238000000034 method Methods 0.000 claims 4
- 108090000623 proteins and genes Proteins 0.000 claims 4
- 102000004169 proteins and genes Human genes 0.000 claims 4
- 206010027940 Mood altered Diseases 0.000 claims 3
- 244000082988 Secale cereale Species 0.000 claims 3
- 235000015872 dietary supplement Nutrition 0.000 claims 3
- 239000013573 pollen allergen Substances 0.000 claims 3
- 208000024891 symptom Diseases 0.000 claims 3
- 208000006820 Arthralgia Diseases 0.000 claims 2
- 240000004585 Dactylis glomerata Species 0.000 claims 2
- 206010060800 Hot flush Diseases 0.000 claims 2
- 101000763602 Manilkara zapota Thaumatin-like protein 1 Proteins 0.000 claims 2
- 101000763586 Manilkara zapota Thaumatin-like protein 1a Proteins 0.000 claims 2
- 101000966653 Musa acuminata Glucan endo-1,3-beta-glucosidase Proteins 0.000 claims 2
- 235000011613 Pinus brutia Nutrition 0.000 claims 2
- 235000008582 Pinus sylvestris Nutrition 0.000 claims 2
- 241000218626 Pinus sylvestris Species 0.000 claims 2
- 241000209504 Poaceae Species 0.000 claims 2
- 206010036618 Premenstrual syndrome Diseases 0.000 claims 2
- 239000006286 aqueous extract Substances 0.000 claims 2
- 210000000805 cytoplasm Anatomy 0.000 claims 2
- 230000000378 dietary effect Effects 0.000 claims 2
- 230000009245 menopause Effects 0.000 claims 2
- 230000007510 mood change Effects 0.000 claims 2
- 108090000765 processed proteins & peptides Proteins 0.000 claims 2
- 239000007787 solid Substances 0.000 claims 2
- 238000001694 spray drying Methods 0.000 claims 2
- 239000000126 substance Substances 0.000 claims 2
- 206010006187 Breast cancer Diseases 0.000 claims 1
- 208000026310 Breast neoplasm Diseases 0.000 claims 1
- 206010006298 Breast pain Diseases 0.000 claims 1
- 102000012286 Chitinases Human genes 0.000 claims 1
- 108010022172 Chitinases Proteins 0.000 claims 1
- 206010009866 Cold sweat Diseases 0.000 claims 1
- 206010012374 Depressed mood Diseases 0.000 claims 1
- 108010033128 Glucan Endo-1,3-beta-D-Glucosidase Proteins 0.000 claims 1
- 208000033830 Hot Flashes Diseases 0.000 claims 1
- 206010022998 Irritability Diseases 0.000 claims 1
- 208000006662 Mastodynia Diseases 0.000 claims 1
- 208000019695 Migraine disease Diseases 0.000 claims 1
- 206010028980 Neoplasm Diseases 0.000 claims 1
- 241000218641 Pinaceae Species 0.000 claims 1
- 235000008331 Pinus X rigitaeda Nutrition 0.000 claims 1
- 241000018646 Pinus brutia Species 0.000 claims 1
- 206010060862 Prostate cancer Diseases 0.000 claims 1
- 208000000236 Prostatic Neoplasms Diseases 0.000 claims 1
- 241000209056 Secale Species 0.000 claims 1
- 206010043268 Tension Diseases 0.000 claims 1
- 208000021017 Weight Gain Diseases 0.000 claims 1
- 235000005824 Zea mays ssp. parviglumis Nutrition 0.000 claims 1
- 235000002017 Zea mays subsp mays Nutrition 0.000 claims 1
- 108010019077 beta-Amylase Proteins 0.000 claims 1
- 201000011510 cancer Diseases 0.000 claims 1
- 239000002775 capsule Substances 0.000 claims 1
- 235000005822 corn Nutrition 0.000 claims 1
- 229940055378 corn pollen extract Drugs 0.000 claims 1
- 230000001086 cytosolic effect Effects 0.000 claims 1
- 235000005911 diet Nutrition 0.000 claims 1
- 230000001544 dysphoric effect Effects 0.000 claims 1
- 235000013305 food Nutrition 0.000 claims 1
- 230000003054 hormonal effect Effects 0.000 claims 1
- 238000001794 hormone therapy Methods 0.000 claims 1
- 239000007788 liquid Substances 0.000 claims 1
- 230000005906 menstruation Effects 0.000 claims 1
- 206010027599 migraine Diseases 0.000 claims 1
- 230000036651 mood Effects 0.000 claims 1
- 239000000843 powder Substances 0.000 claims 1
- 238000000926 separation method Methods 0.000 claims 1
- 208000019116 sleep disease Diseases 0.000 claims 1
- 238000003809 water extraction Methods 0.000 claims 1
- 230000004584 weight gain Effects 0.000 claims 1
- 235000019786 weight gain Nutrition 0.000 claims 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/899—Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/11—Aldehydes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
- A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/13—Coniferophyta (gymnosperms)
- A61K36/15—Pinaceae (Pine family), e.g. pine or cedar
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/168—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from plants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/44—Oxidoreductases (1)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/47—Hydrolases (3) acting on glycosyl compounds (3.2), e.g. cellulases, lactases
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2068—Compounds of unknown constitution, e.g. material from plants or animals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4875—Compounds of unknown constitution, e.g. material from plants or animals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Engineering & Computer Science (AREA)
- Botany (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Biotechnology (AREA)
- Medical Informatics (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Alternative & Traditional Medicine (AREA)
- Zoology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Molecular Biology (AREA)
- Endocrinology (AREA)
- Diabetes (AREA)
- Medicines Containing Plant Substances (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Cosmetics (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Claims (15)
1. Oralni pripravak koji sadrži:
– ekstrakt peludi usjevne raži (Secale cereale L.);
– ekstrakt peludi kukuruza (Zea mays L.);
– ekstrakt peludi običnog bora (Pinus sylvestris L.);
– ekstrakt peludi klupčaste oštrice (Dactylis glomerata L.); i
– ekstrakt tučka kukuruza (Zea mays L.),
naznačen time što navedeni ekstrakti sadrže bjelančevinu ili peptid izveden iz navedene bjelančevine koja je beta-1,3-glukanaza, pri čemu je navedeni pripravak poželjno u obliku tablete, kapsule, mekog gela, polukrute tvari, krute tvari, tekućine ili praška.
2. Pripravak prema zahtjevu 1, naznačen time da navedeni ekstrakti nadalje sadrže barem jednu drugu bjelančevinu ili peptid izveden iz navedene druge bjelančevine odabrane iz skupine peludnih alergena Lol p 4, peludnog alergena Sec 4 (Secale cereale), glukan endo-1,3-beta-D-glukozidaze, beta- amilaze, hitinaze ili bilo koje njihove kombinacije.
3. Pripravak prema jednom od zahtjeva 1 ili 2, naznačen time što, s jedne strane, uključuje:
– ekstrakt peludi Secale cereale L.;
– ekstrakt peludi Zea mays L.;
– ekstrakt peludi Pinus sylvestris L.;
– ekstrakt peludi Dactylis glomerata L; i
– ekstrakt tučka Zea mays L.;
a s druge strane, barem sljedeće markere:
– beta-1,3-glukanaza; i
– peludni alergen Sec 4.
4. Pripravak prema jednom od prethodnih zahtjeva, naznačen time što se navedena mješavina različitih ekstrakata suši raspršivanjem.
5. Pripravak prema bilo kojem od prethodnih zahtjeva, naznačen time što su ekstrakti peludi citoplazmatski ekstrakti peludi.
6. Pripravak prema bilo kojem prethodnom zahtjevu, naznačen time što se primjenjuje kao farmaceutski, dijetetski ili prehrambeni dodatak, zdravstveni dodatak ili medicinski/dijetetski prehrambeni proizvod.
7. Postupak za pripremu vodenog ekstrakta peludi i tučka, dobivenog iz biljke ili biljaka koje po mogućnosti pripadaju obitelji Pinaceae i/ili trava (Poaceae) koji se sastoji od uzastopnih faza:
a) vodene ekstrakcije peludi;
b) vodene ekstrakcije peludi i tučka;
c) sušenja raspršivanjem ekstrakata dobivenih u koracima a) i b);
d) izdvajanja navedenih ekstrakata peludi i tučka iz biljke ili biljaka dobivenih u c);
naznačen time da je temperatura ekstrakcija strogo ispod 45 °C.
8. Postupak prema zahtjevu 7, naznačen time da je početna temperatura koraka sušenja raspršivanjem između 138 °C i 168 °C.
9. Postupak prema bilo kojem od zahtjeva 7 ili 8, naznačen time što su vodene ekstrakcije peludi vodene ekstrakcije citoplazme peludi.
10. Vodeni ekstrakt peludi ili citoplazme peludi i tučka koji se vjerojatno može dobiti postupkom prema jednom od zahtjeva od 7 do 9.
11. Pripravak prema bilo kojem od zahtjeva od 1 do 6 ili ekstrakt prema zahtjevu 10 za upotrebu u liječenju simptoma perimenopauze, postmenopauze i/ili menopauze, poželjno menopauze.
12. Pripravak ili ekstrakt za njegovu upotrebu prema zahtjevu 11, naznačen time da su navedeni simptomi navale vrućine, problemi sa spavanjem, bolovi u zglobovima, promjene raspoloženja (promjene raspoloženja i loše raspoloženje, opće depresivno raspoloženje, razdražljivost, živčane napetosti), umor, promjena libida, bolovi u dojkama, migrena, povećanje tjelesne težine, hladan znoj i/ili bolovi u zglobovima.
13. Pripravak prema bilo kojem od zahtjeva od 1 do 6 ili ekstrakt prema zahtjevu 10, naznačen time da se upotrebljava u liječenju predmenstrualnog sindroma (PMS), poželjno u liječenju predmenstrualnih disforičnih problema i omogućavanju opskrbe tonusom i vitalnošću, smanjenju umora, pomoći u održavanju pozitivnog raspoloženja i povećanju udobnosti prije i tijekom menstruacije.
14. Pripravak prema bilo kojem od zahtjeva od 1 do 6 ili ekstrakt prema zahtjevu 10 za upotrebu u liječenju navala vrućine izazvanih hormonoterapijom kod pacijenata s rakom, poželjno rakom dojke ili rakom prostate.
15. Pripravak prema bilo kojem od zahtjeva od 1 do 6 ili ekstrakt prema zahtjevu 10 za upotrebu u liječenju simptoma andropauze i nelagode povezane s hormonskom neravnotežom kod muškaraca.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR1670480A FR3055215B1 (fr) | 2016-08-31 | 2016-08-31 | Composition comprenant des extraits de pollen et /ou de pistils |
EP17758863.9A EP3506918B1 (fr) | 2016-08-31 | 2017-08-28 | Composition comprenant des extraits de pollens et/ou de pistils, procede de preparation et utilisations associees |
Publications (1)
Publication Number | Publication Date |
---|---|
HRP20230508T1 true HRP20230508T1 (hr) | 2023-09-15 |
Family
ID=57796730
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HRP20230508TT HRP20230508T1 (hr) | 2016-08-31 | 2017-08-28 | Pripravak koji sadrži ekstrakte peludi i/ili tučka, postupak pripreme i povezane upotrebe |
Country Status (13)
Country | Link |
---|---|
US (1) | US12029775B2 (hr) |
EP (1) | EP3506918B1 (hr) |
JP (1) | JP7142002B2 (hr) |
CN (1) | CN109922816A (hr) |
CA (1) | CA3031720A1 (hr) |
DK (1) | DK3506918T3 (hr) |
ES (1) | ES2948114T3 (hr) |
FR (1) | FR3055215B1 (hr) |
HR (1) | HRP20230508T1 (hr) |
PL (1) | PL3506918T3 (hr) |
PT (1) | PT3506918T (hr) |
RS (1) | RS64269B1 (hr) |
WO (1) | WO2018041790A1 (hr) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR3091819B1 (fr) * | 2019-01-18 | 2021-04-23 | Serelys Pharma | Composition pour le traitement et/ou la prevention des symptomes du bas appareil urinaire |
IT202000027423A1 (it) * | 2020-11-16 | 2022-05-16 | Kolinpharma S P A | Composizione multicomponente e suo uso nel trattamento di patologie della prostata |
FR3121351B1 (fr) * | 2021-03-30 | 2024-03-08 | Axeen Pharma | Composition à base de spiruline et ses utilisations pour le renforcement de l’immunité |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1123116A (zh) * | 1994-11-22 | 1996-05-29 | 杨学忠 | 一种植物保健饮料及其制作方法 |
ATE186054T1 (de) | 1995-06-30 | 1999-11-15 | Cerbios Pharma Sa | Glykoside, deren zuckerfreie abbauprodukte und derivate derselben |
SE0003092D0 (sv) * | 2000-09-01 | 2000-09-01 | Natumin Pharma Ab | New Use |
CN101116502A (zh) * | 2007-08-24 | 2008-02-06 | 河南省泷鑫医药保健品有限公司 | 一种降血糖的保健品及其制备方法 |
BR112014015354A8 (pt) * | 2011-12-23 | 2017-06-13 | Horphag Res Ip Qr Ltd | composição de extratos enriquecidos com elagitaninos no bem-estar sexual |
JP2014024800A (ja) * | 2012-07-27 | 2014-02-06 | Osaka Bioscience Institute | 睡眠作用又は鎮静作用増強剤、及び睡眠作用又は鎮静作用増強剤を含む製剤 |
US9211298B2 (en) * | 2012-11-16 | 2015-12-15 | Song Gao | Compositions containing enriched natural crocin and/or crocetin, and their therapeutic or nutraceutical uses |
-
2016
- 2016-08-31 FR FR1670480A patent/FR3055215B1/fr active Active
-
2017
- 2017-08-08 US US16/329,034 patent/US12029775B2/en active Active
- 2017-08-28 JP JP2019512717A patent/JP7142002B2/ja active Active
- 2017-08-28 RS RS20230455A patent/RS64269B1/sr unknown
- 2017-08-28 CA CA3031720A patent/CA3031720A1/fr active Pending
- 2017-08-28 CN CN201780053175.0A patent/CN109922816A/zh active Pending
- 2017-08-28 HR HRP20230508TT patent/HRP20230508T1/hr unknown
- 2017-08-28 DK DK17758863.9T patent/DK3506918T3/da active
- 2017-08-28 EP EP17758863.9A patent/EP3506918B1/fr active Active
- 2017-08-28 PT PT177588639T patent/PT3506918T/pt unknown
- 2017-08-28 PL PL17758863.9T patent/PL3506918T3/pl unknown
- 2017-08-28 WO PCT/EP2017/071573 patent/WO2018041790A1/fr unknown
- 2017-08-28 ES ES17758863T patent/ES2948114T3/es active Active
Also Published As
Publication number | Publication date |
---|---|
ES2948114T3 (es) | 2023-08-31 |
PT3506918T (pt) | 2023-06-21 |
JP2019532039A (ja) | 2019-11-07 |
PL3506918T3 (pl) | 2023-06-26 |
FR3055215B1 (fr) | 2020-02-14 |
CN109922816A (zh) | 2019-06-21 |
CA3031720A1 (fr) | 2018-03-08 |
EP3506918B1 (fr) | 2023-04-19 |
DK3506918T3 (da) | 2023-06-06 |
JP7142002B2 (ja) | 2022-09-26 |
WO2018041790A1 (fr) | 2018-03-08 |
FR3055215A1 (fr) | 2018-03-02 |
EP3506918A1 (fr) | 2019-07-10 |
US12029775B2 (en) | 2024-07-09 |
RS64269B1 (sr) | 2023-07-31 |
US20190216877A1 (en) | 2019-07-18 |
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