HRP20200245T1 - Postupci za pripravu (s)-1-(3-etoksi-4metoksifenil)-2-metansulfoniletilamina - Google Patents

Postupci za pripravu (s)-1-(3-etoksi-4metoksifenil)-2-metansulfoniletilamina

Info

Publication number: HRP20200245T1
Authority: HR; Croatia
Prior art keywords: methanesulfonylethylamine; ethoxy; processes; preparation
Prior art date: 2012-02-21

Application number

HRP20200245TT

Other languages

English (en)

Inventor

Jasti VENKATESWARALU

Chinnapillai Rajendiran

Nallamaddi Ravikumar Reddy

Terrence Joseph Connolly

Alexander L. Ruchelman

Jeffrey Eckert

Anthony Joseph Frank

Original Assignee

Amgen (Europe) GmbH

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2012-02-21

Filing date

2020-02-13

Publication date

2020-05-15

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=47755073&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HRP20200245(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2020-02-13 Application filed by Amgen (Europe) GmbH filed Critical Amgen (Europe) GmbH

2020-05-15 Publication of HRP20200245T1 publication Critical patent/HRP20200245T1/hr

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C315/00—Preparation of sulfones; Preparation of sulfoxides
- C07C315/04—Preparation of sulfones; Preparation of sulfoxides by reactions not involving the formation of sulfone or sulfoxide groups
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C313/00—Sulfinic acids; Sulfenic acids; Halides, esters or anhydrides thereof; Amides of sulfinic or sulfenic acids, i.e. compounds having singly-bound oxygen atoms of sulfinic or sulfenic groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C313/02—Sulfinic acids; Derivatives thereof
- C07C313/06—Sulfinamides
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C317/00—Sulfones; Sulfoxides
- C07C317/24—Sulfones; Sulfoxides having sulfone or sulfoxide groups and doubly-bound oxygen atoms bound to the same carbon skeleton
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C317/00—Sulfones; Sulfoxides
- C07C317/26—Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
- C07C317/28—Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton with sulfone or sulfoxide groups bound to acyclic carbon atoms of the carbon skeleton
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/05—Isotopically modified compounds, e.g. labelled
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/07—Optical isomers

HRP20200245TT 2012-02-21 2020-02-13 Postupci za pripravu (s)-1-(3-etoksi-4metoksifenil)-2-metansulfoniletilamina HRP20200245T1 (hr)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US201261601226P	2012-02-21	2012-02-21
EP18168969.6A EP3378850B8 (en)	2012-02-21	2013-02-20	Processes for the preparation of (s)-1-(3-ethoxy-4methoxyphenyl)-2-methanesulfonylethylamine

Publications (1)

Publication Number	Publication Date
HRP20200245T1 true HRP20200245T1 (hr)	2020-05-15

Family

ID=47755073

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
HRP20191249TT HRP20191249T1 (hr)	2012-02-21	2019-07-12	Procesi za pripremu (s)-1-(3-etoksi-4metoksifenil)-2-metansulfoniletilamina
HRP20200245TT HRP20200245T1 (hr)	2012-02-21	2020-02-13	Postupci za pripravu (s)-1-(3-etoksi-4metoksifenil)-2-metansulfoniletilamina

Family Applications Before (1)

Application Number	Title	Priority Date	Filing Date
HRP20191249TT HRP20191249T1 (hr)	2012-02-21	2019-07-12	Procesi za pripremu (s)-1-(3-etoksi-4metoksifenil)-2-metansulfoniletilamina

Country Status (36)

Country	Link
US (3)	US9187417B2 (hr)
EP (4)	EP3378850B8 (hr)
JP (1)	JP2015509496A (hr)
KR (1)	KR101993248B1 (hr)
CN (3)	CN107033042A (hr)
AR (2)	AR090100A1 (hr)
AU (1)	AU2013203283B2 (hr)
BR (3)	BR122021020046B1 (hr)
CA (1)	CA2864517A1 (hr)
CO (1)	CO7061071A2 (hr)
CR (1)	CR20140395A (hr)
CY (2)	CY1121833T1 (hr)
DK (2)	DK3312156T3 (hr)
ES (3)	ES2675168T3 (hr)
HK (1)	HK1205501A1 (hr)
HR (2)	HRP20191249T1 (hr)
HU (2)	HUE048412T2 (hr)
IL (3)	IL234135A (hr)
IN (1)	IN2014DN06740A (hr)
LT (2)	LT3378850T (hr)
MX (2)	MX350731B (hr)
MY (1)	MY168296A (hr)
NI (1)	NI201400093A (hr)
NZ (1)	NZ628028A (hr)
PH (1)	PH12014501865B1 (hr)
PL (2)	PL3312156T3 (hr)
PT (2)	PT3378850T (hr)
RS (2)	RS60036B1 (hr)
RU (1)	RU2632875C2 (hr)
SG (1)	SG11201405035XA (hr)
SI (2)	SI3312156T1 (hr)
TR (1)	TR201910430T4 (hr)
TW (1)	TW201336815A (hr)
UA (1)	UA116773C2 (hr)
WO (1)	WO2013126360A2 (hr)
ZA (1)	ZA201405892B (hr)

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WO2014204825A1 (en)	2013-06-17	2014-12-24	Celgene Corporation	Tablet formulations of (+)-2-[1 -(3-ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]-4-acetylaminoisoindoline-1,3-dione
IN2014MU01283A (hr)	2014-04-04	2015-10-09	Cadila Healthcare Ltd
WO2015173792A1 (en)	2014-05-11	2015-11-19	Mapi Pharma Ltd.	Amorphous form of apremilast
EP2949645A1 (en)	2014-05-28	2015-12-02	LEK Pharmaceuticals d.d.	Processes for the preparation of ß-aminosulfone compounds
CN105622380B (zh) *	2014-10-29	2020-06-30	南京安源生物医药科技有限公司	一种阿普斯特的制备方法及其中间体
CN104447445B (zh) *	2014-12-05	2016-07-06	新发药业有限公司	一种合成阿普斯特中间体的制备方法
CN104761474B (zh) *	2015-03-11	2016-11-30	中山奕安泰医药科技有限公司	一种阿普斯特手性胺中间体的合成方法
CN104744323B (zh) *	2015-03-11	2016-08-31	中山奕安泰医药科技有限公司	一种阿普斯特手性胺中间体的合成工艺
CN104803897A (zh) *	2015-04-23	2015-07-29	中山奕安泰医药科技有限公司	一种阿普斯特中间体的合成工艺
US10370329B2 (en) *	2015-04-27	2019-08-06	Mylan Laboratories Limited	Process for the enantiomeric resolution of apremilast intermediates
US20180334429A1 (en) *	2015-06-09	2018-11-22	Dr. Reddy's Laboratories Limited	Process for preparation of apremilast and its intermediates
EP3106457A1 (en)	2015-06-15	2016-12-21	LEK Pharmaceuticals d.d.	A novel synthetic pathway towards apremilast
EP3144393A1 (en) *	2015-09-18	2017-03-22	LEK Pharmaceuticals d.d.	A synthetic pathway towards apremilast
EP3356327A1 (en)	2015-09-29	2018-08-08	Pliva Hrvatska D.O.O.	Processes for the preparation of apremilast and intermediates thereof
WO2017085568A1 (en) *	2015-11-19	2017-05-26	Alembic Pharmaceuticals Limited	An improved process and novel polymorphic form of apremilast
CN105330586B (zh) *	2015-11-27	2017-12-22	东华大学	一种阿普斯特的制备方法
CN105461602B (zh) *	2015-11-27	2018-01-02	东华大学	手性S或R‑3‑乙氧基‑4‑甲氧基‑α‑[(甲磺酰基)甲基]苯甲醇的制备方法
WO2017094031A2 (en) *	2015-12-04	2017-06-08	Sun Pharmaceutical Industries Limited	Novel process for preparation of apremilast
CN106866475B (zh) *	2015-12-11	2018-03-30	北大方正集团有限公司	一种阿普斯特中间体及其制备方法
WO2017179065A1 (en)	2016-04-15	2017-10-19	Davuluri Ramamohan Rao	Improved process for the preparation of apremilast
US10196355B2 (en)	2016-06-20	2019-02-05	Johnson Matthey Public Limited Company	Forms of apremilast
CN106543050B (zh) *	2016-09-28	2018-04-10	中南大学湘雅医院	一种阿普斯特中间体的合成工艺
WO2018061034A1 (en) *	2016-09-30	2018-04-05	Sun Pharmaceutical Industries Limited	Novel process for the preparation of 1-(3-ethoxy-4-methoxy-phenyl)-2-methylsulfonyl-ethanamine
WO2018086762A1 (de)	2016-11-10	2018-05-17	Sms Group Gmbh	VERFAHREN ZUM HERSTELLEN EINES METALLISCHEN BANDES IN EINER GIEßWALZANLAGE
CN107445875A (zh) *	2017-03-22	2017-12-08	陕西科技大学	一种用于制备阿普斯特的高纯度中间体的手性拆分方法
EP3606907B1 (en)	2017-04-04	2021-01-20	Quimica Sintetica, S.A.	Racemic beta-aminosulfone compounds
SI3606908T1 (sl)	2017-04-04	2020-10-30	Quimica Sintetica, S.A.	Delitev racemičnih beta-aminosulfonskih spojin
CN107966509B (zh) *	2017-11-23	2020-06-23	中山奕安泰医药科技有限公司	一种(s)-1-(3-乙氧基-4-甲氧基苯基)-2-(甲基磺酰基)乙胺的检测方法
CN107827722B (zh) *	2017-11-23	2021-02-19	中山奕安泰医药科技有限公司	一种3-乙氧基-4-甲氧基苯甲醛的合成方法
CN107976501B (zh) *	2017-11-23	2020-08-25	中山奕安泰医药科技有限公司	一种1-(3-乙氧基-4-甲氧基苯基)-2-(甲基磺酰基)乙胺的检测方法
CN108008035B (zh) *	2017-11-23	2020-07-07	中山奕安泰医药科技有限公司	3-乙氧基-4-甲氧基苯甲醛纯度的检测方法
CN107941945B (zh) *	2017-11-23	2020-12-22	中山奕安泰医药科技有限公司	一种3-乙氧基-4-甲氧基苯甲腈的检测方法
CN108084066A (zh) *	2017-12-12	2018-05-29	中山大学	一种阿普斯特及对映异构体的合成方法
JP6673614B1 (ja) *	2018-10-16	2020-03-25	東芝エレベータ株式会社	防音装置
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2013
- 2013-02-19 AR ARP130100512A patent/AR090100A1/es active IP Right Grant
- 2013-02-20 TR TR2019/10430T patent/TR201910430T4/tr unknown
- 2013-02-20 HU HUE18168969A patent/HUE048412T2/hu unknown
- 2013-02-20 PT PT181689696T patent/PT3378850T/pt unknown
- 2013-02-20 MX MX2016016157A patent/MX350731B/es unknown
- 2013-02-20 LT LTEP18168969.6T patent/LT3378850T/lt unknown
- 2013-02-20 CA CA2864517A patent/CA2864517A1/en not_active Withdrawn
- 2013-02-20 EP EP18168969.6A patent/EP3378850B8/en active Active
- 2013-02-20 PL PL17197504T patent/PL3312156T3/pl unknown
- 2013-02-20 EP EP20150560.9A patent/EP3702347B1/en active Active
- 2013-02-20 WO PCT/US2013/026780 patent/WO2013126360A2/en active Application Filing
- 2013-02-20 CN CN201710255841.0A patent/CN107033042A/zh active Pending
- 2013-02-20 JP JP2014558783A patent/JP2015509496A/ja active Pending
- 2013-02-20 PT PT17197504T patent/PT3312156T/pt unknown
- 2013-02-20 RU RU2014138037A patent/RU2632875C2/ru active
- 2013-02-20 US US13/771,164 patent/US9187417B2/en active Active
- 2013-02-20 UA UAA201410289A patent/UA116773C2/uk unknown
- 2013-02-20 ES ES13706898.7T patent/ES2675168T3/es active Active
- 2013-02-20 ES ES17197504T patent/ES2735801T3/es active Active
- 2013-02-20 NZ NZ628028A patent/NZ628028A/en unknown
- 2013-02-20 EP EP17197504.8A patent/EP3312156B1/en active Active
- 2013-02-20 TW TW102105901A patent/TW201336815A/zh unknown
- 2013-02-20 SI SI201331526T patent/SI3312156T1/sl unknown
- 2013-02-20 BR BR122021020046-7A patent/BR122021020046B1/pt active IP Right Grant
- 2013-02-20 CN CN202110092737.0A patent/CN112812044B/zh active Active
- 2013-02-20 PL PL18168969T patent/PL3378850T3/pl unknown
- 2013-02-20 SI SI201331685T patent/SI3378850T1/sl unknown
- 2013-02-20 DK DK17197504.8T patent/DK3312156T3/da active
- 2013-02-20 HU HUE17197504 patent/HUE044192T2/hu unknown
- 2013-02-20 MX MX2014010002A patent/MX344190B/es active IP Right Grant
- 2013-02-20 ES ES18168969T patent/ES2773686T3/es active Active
- 2013-02-20 SG SG11201405035XA patent/SG11201405035XA/en unknown
- 2013-02-20 EP EP13706898.7A patent/EP2817288B1/en active Active
- 2013-02-20 LT LTEP17197504.8T patent/LT3312156T/lt unknown
- 2013-02-20 DK DK18168969.6T patent/DK3378850T3/da active
- 2013-02-20 RS RS20200185A patent/RS60036B1/sr unknown
- 2013-02-20 KR KR1020147026186A patent/KR101993248B1/ko active IP Right Grant
- 2013-02-20 RS RS20190895A patent/RS59071B1/sr unknown
- 2013-02-20 AU AU2013203283A patent/AU2013203283B2/en active Active
- 2013-02-20 BR BR112014020444-6A patent/BR112014020444B1/pt active IP Right Grant
- 2013-02-20 BR BR122021020040-8A patent/BR122021020040B1/pt active IP Right Grant
- 2013-02-20 CN CN201380020005.4A patent/CN104245668B/zh active Active
- 2013-02-20 MY MYPI2014702288A patent/MY168296A/en unknown
- 2013-02-20 IN IN6740DEN2014 patent/IN2014DN06740A/en unknown
2014
- 2014-08-12 ZA ZA2014/05892A patent/ZA201405892B/en unknown
- 2014-08-14 IL IL234135A patent/IL234135A/en active IP Right Grant
- 2014-08-18 PH PH12014501865A patent/PH12014501865B1/en unknown
- 2014-08-20 NI NI201400093A patent/NI201400093A/es unknown
- 2014-08-21 CR CR20140395A patent/CR20140395A/es unknown
- 2014-08-21 CO CO14183628A patent/CO7061071A2/es unknown
2015
- 2015-06-25 HK HK15106059.8A patent/HK1205501A1/xx unknown
- 2015-10-14 US US14/882,564 patent/US9586897B2/en active Active
2017
- 2017-01-25 US US15/414,782 patent/US9688623B2/en active Active
- 2017-05-23 IL IL252459A patent/IL252459B/en active IP Right Grant
2019
- 2019-07-11 CY CY20191100742T patent/CY1121833T1/el unknown
- 2019-07-12 HR HRP20191249TT patent/HRP20191249T1/hr unknown
2020
- 2020-01-10 AR ARP200100066A patent/AR117963A2/es unknown
- 2020-02-13 HR HRP20200245TT patent/HRP20200245T1/hr unknown
- 2020-02-21 CY CY20201100163T patent/CY1122799T1/el unknown
- 2020-03-04 IL IL273050A patent/IL273050A/en active IP Right Grant

Also Published As

Publication number	Publication date
RS60036B1 (sr)	2020-04-30
EP3378850A1 (en)	2018-09-26
SI3312156T1 (sl)	2019-09-30
HK1205501A1 (en)	2015-12-18
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MY168296A (en)	2018-10-23

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