HRP20160767T1 - Postupak za pripremu kristalnog oblika i agomelatina - Google Patents

Postupak za pripremu kristalnog oblika i agomelatina

Info

Publication number
HRP20160767T1
HRP20160767T1 HRP20160767TT HRP20160767T HRP20160767T1 HR P20160767 T1 HRP20160767 T1 HR P20160767T1 HR P20160767T T HRP20160767T T HR P20160767TT HR P20160767 T HRP20160767 T HR P20160767T HR P20160767 T1 HRP20160767 T1 HR P20160767T1
Authority
HR
Croatia
Prior art keywords
agomelatine
preparation
crystalline form
crystalline
Prior art date
Application number
HRP20160767TT
Other languages
English (en)
Inventor
Giorgio Bertolini
Bruno De Angelis
Original Assignee
Laboratorio Chimico Internazionale S.P.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Laboratorio Chimico Internazionale S.P.A. filed Critical Laboratorio Chimico Internazionale S.P.A.
Publication of HRP20160767T1 publication Critical patent/HRP20160767T1/hr

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00Carboxylic acid amides
    • C07C233/01Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/16Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms
    • C07C233/24Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a six-membered aromatic ring
    • C07C233/25Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a six-membered aromatic ring having the carbon atom of the carboxamide group bound to a hydrogen atom or to a carbon atom of an acyclic saturated carbon skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00Carboxylic acid amides
    • C07C233/01Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/16Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms
    • C07C233/17Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom
    • C07C233/18Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom having the carbon atom of the carboxamide group bound to a hydrogen atom or to a carbon atom of an acyclic saturated carbon skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00Preparation of carboxylic acid amides
    • C07C231/22Separation; Purification; Stabilisation; Use of additives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13Crystalline forms, e.g. polymorphs
HRP20160767TT 2011-08-03 2016-06-30 Postupak za pripremu kristalnog oblika i agomelatina HRP20160767T1 (hr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
PCT/IB2011/001805 WO2013017903A1 (en) 2011-08-03 2011-08-03 Process for the preparation of crystalline form i of agomelatine
EP11770507.9A EP2739605B1 (en) 2011-08-03 2011-08-03 Process for the preparation of crystalline form i of agomelatine

Publications (1)

Publication Number Publication Date
HRP20160767T1 true HRP20160767T1 (hr) 2016-08-12

Family

ID=44802320

Family Applications (1)

Application Number Title Priority Date Filing Date
HRP20160767TT HRP20160767T1 (hr) 2011-08-03 2016-06-30 Postupak za pripremu kristalnog oblika i agomelatina

Country Status (16)

Country Link
US (1) US20150291508A1 (hr)
EP (1) EP2739605B1 (hr)
CN (1) CN103827078B (hr)
BR (1) BR112014002523A2 (hr)
CA (1) CA2843827A1 (hr)
CY (1) CY1117823T1 (hr)
DK (1) DK2739605T3 (hr)
EA (1) EA024650B1 (hr)
ES (1) ES2577177T3 (hr)
HR (1) HRP20160767T1 (hr)
HU (1) HUE030282T2 (hr)
IN (1) IN2014CN00348A (hr)
PL (1) PL2739605T3 (hr)
PT (1) PT2739605E (hr)
SI (1) SI2739605T1 (hr)
WO (1) WO2013017903A1 (hr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104876830A (zh) * 2015-06-09 2015-09-02 江苏中邦制药有限公司 一种阿戈美拉汀i晶型晶体的制备方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2658818B1 (fr) 1990-02-27 1993-12-31 Adir Cie Nouveaux derives a structure naphtalenique, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
FR2866335B1 (fr) 2004-02-13 2006-05-26 Servier Lab Nouveau procede de synthese de l'agomelatine
EP2319827A1 (en) * 2009-11-09 2011-05-11 Ratiopharm GmbH Process for the production of polymorph form I of agomelatine
CN101704763B (zh) 2009-11-25 2012-03-28 天津泰普药品科技发展有限公司 阿戈美拉汀i型晶体的制备方法
CN101921205B (zh) * 2010-08-30 2013-11-20 江苏恩华药业股份有限公司 阿戈美拉汀ⅰ晶型的制备方法

Also Published As

Publication number Publication date
ES2577177T3 (es) 2016-07-13
PT2739605E (pt) 2016-06-20
CN103827078A (zh) 2014-05-28
PL2739605T3 (pl) 2016-11-30
SI2739605T1 (sl) 2016-08-31
BR112014002523A2 (pt) 2017-03-14
HUE030282T2 (en) 2017-05-29
EA024650B1 (ru) 2016-10-31
CY1117823T1 (el) 2017-05-17
EP2739605B1 (en) 2016-04-27
DK2739605T3 (en) 2016-07-25
EA201400188A1 (ru) 2014-07-30
EP2739605A1 (en) 2014-06-11
WO2013017903A1 (en) 2013-02-07
IN2014CN00348A (hr) 2015-04-03
CA2843827A1 (en) 2013-02-07
CN103827078B (zh) 2015-08-05
US20150291508A1 (en) 2015-10-15

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