HRP20151444T1 - Sredstva za lijeäśenje i postupci lijeäśenja dlbcl - Google Patents

Sredstva za lijeäśenje i postupci lijeäśenja dlbcl

Info

Publication number
HRP20151444T1
HRP20151444T1 HRP20151444TT HRP20151444T HRP20151444T1 HR P20151444 T1 HRP20151444 T1 HR P20151444T1 HR P20151444T T HRP20151444T T HR P20151444TT HR P20151444 T HRP20151444 T HR P20151444T HR P20151444 T1 HRP20151444 T1 HR P20151444T1
Authority
HR
Croatia
Prior art keywords
methods
treating dlbcl
dlbcl
treating
Prior art date
Application number
HRP20151444TT
Other languages
English (en)
Inventor
Gerhard Zugmaier
Dirk Nagorsen
Juergen Scheele
Original Assignee
Amgen Research (Munich) Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=45023802&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HRP20151444(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Amgen Research (Munich) Gmbh filed Critical Amgen Research (Munich) Gmbh
Publication of HRP20151444T1 publication Critical patent/HRP20151444T1/hr
Publication of HRP20151444T4 publication Critical patent/HRP20151444T4/hr

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2809Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against the T-cell receptor (TcR)-CD3 complex
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/39558Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against tumor tissues, cells, antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/46Hybrid immunoglobulins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/545Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/30Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/31Immunoglobulins specific features characterized by aspects of specificity or valency multispecific
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76Antagonist effect on antigen, e.g. neutralization or inhibition of binding
HRP20151444TT 2010-10-27 2015-12-31 Sredstva za liječenje i postupci liječenja dlbcl HRP20151444T4 (hr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US40710710P 2010-10-27 2010-10-27
EP11787633.4A EP2632954B2 (en) 2010-10-27 2011-10-27 Means and methods for treating dlbcl
PCT/EP2011/068851 WO2012055961A1 (en) 2010-10-27 2011-10-27 Means and methods for treating dlbcl

Publications (2)

Publication Number Publication Date
HRP20151444T1 true HRP20151444T1 (hr) 2016-01-29
HRP20151444T4 HRP20151444T4 (hr) 2021-08-20

Family

ID=45023802

Family Applications (2)

Application Number Title Priority Date Filing Date
HRP20151444TT HRP20151444T4 (hr) 2010-10-27 2015-12-31 Sredstva za liječenje i postupci liječenja dlbcl
HRP20180882TT HRP20180882T1 (hr) 2010-10-27 2018-06-05 Sredstva za i postupci liječenja dlbcl

Family Applications After (1)

Application Number Title Priority Date Filing Date
HRP20180882TT HRP20180882T1 (hr) 2010-10-27 2018-06-05 Sredstva za i postupci liječenja dlbcl

Country Status (31)

Country Link
US (2) US9192665B2 (hr)
EP (3) EP3412687B1 (hr)
JP (3) JP5997168B2 (hr)
KR (1) KR101889995B1 (hr)
CN (2) CN105251003B (hr)
AU (1) AU2011322581B2 (hr)
CA (1) CA2815119C (hr)
CL (1) CL2013001138A1 (hr)
CR (1) CR20130245A (hr)
CY (3) CY1117155T1 (hr)
DK (3) DK2632954T4 (hr)
EA (1) EA032139B1 (hr)
ES (3) ES2675299T3 (hr)
HK (1) HK1188229A1 (hr)
HR (2) HRP20151444T4 (hr)
HU (3) HUE037786T2 (hr)
IL (3) IL225924A (hr)
LT (2) LT3412687T (hr)
MA (1) MA34619B1 (hr)
ME (1) ME02311B (hr)
MY (1) MY163057A (hr)
NZ (2) NZ609201A (hr)
PL (3) PL3018145T3 (hr)
PT (3) PT2632954E (hr)
RS (3) RS60094B1 (hr)
SG (1) SG189869A1 (hr)
SI (3) SI2632954T2 (hr)
SM (1) SMT201600050B (hr)
TR (1) TR201808019T4 (hr)
UA (1) UA111175C2 (hr)
WO (1) WO2012055961A1 (hr)

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WO2006114115A1 (de) 2005-04-26 2006-11-02 Trion Pharma Gmbh Kombination von antikörpern mit glukokortikoiden zur behandlung von krebs
PT2632954E (pt) * 2010-10-27 2016-02-03 Amgen Res Munich Gmbh Meios e métodos para tratar dlbcl
ES2842937T3 (es) * 2010-11-10 2021-07-15 Amgen Res Munich Gmbh Prevención de efectos adversos provocados por dominios de unión específicos de CD3
JO3529B1 (ar) * 2013-02-08 2020-07-05 Amgen Res Munich Gmbh مضاد التصاق خلايا الدم البيض من أجل التخفيف من الاثار السلبية الممكنة الناتجة عن مجالات ارتباط cd3- المحدد
KR102339240B1 (ko) 2013-10-15 2021-12-15 더 스크립스 리서치 인스티튜트 펩타이드 키메라 항원 수용체 t 세포 스위치 및 이의 용도
WO2016154621A1 (en) 2015-03-26 2016-09-29 The California Institute For Biomedical Research SWITCHABLE NON-scFv CHIMERIC RECEPTORS, SWITCHES, AND USES THEREOF
EP3283113A4 (en) 2015-04-15 2018-12-05 The California Institute for Biomedical Research Optimized pne-based chimeric receptor t cell switches and uses thereof
FI3298033T4 (fi) 2015-05-18 2023-09-22 Tcr2 Therapeutics Inc Koostumuksia ja lääkinnällisiä käyttöjä fuusioproteiineja käyttävälle tcr:n uudelleenohjelmoinnille
JP2019532017A (ja) 2016-07-14 2019-11-07 フレッド ハッチンソン キャンサー リサーチ センター がんを治療するための異なるエピトープ結合を示す複数の二重特異性結合ドメイン構築物
CN109715668A (zh) 2016-08-02 2019-05-03 T细胞受体治疗公司 用于使用融合蛋白进行tcr重编程的组合物和方法
GB2564823B8 (en) 2016-10-07 2022-06-29 Tcr2 Therapeutics Inc Compositions and methods for TCR reprogramming using fusion proteins
JP7149935B2 (ja) 2016-10-19 2022-10-07 ザ スクリプス リサーチ インスティテュート ヒト化された標的化部分および/または最適化されたキメラ抗原受容体相互作用ドメインを有する、キメラ抗原受容体エフェクター細胞スイッチ、ならびにその使用
JP7291396B2 (ja) 2016-11-22 2023-06-15 ティーシーアール2 セラピューティクス インク. 融合タンパク質を用いたtcrの再プログラミングのための組成物及び方法
US10537585B2 (en) 2017-12-18 2020-01-21 Dexcel Pharma Technologies Ltd. Compositions comprising dexamethasone
US11865081B2 (en) 2017-12-29 2024-01-09 Virogin Biotech Canada Ltd. Oncolytic viral delivery of therapeutic polypeptides
WO2020099513A1 (en) * 2018-11-13 2020-05-22 Lipoxen Technologies Limited Glycopolysialylation of blinatumomab
EP3962490A4 (en) * 2019-05-03 2023-01-25 Kite Pharma, Inc. CHEMERA ANTIGEN RECEPTOR IMMUNOTHERAPY ADMINISTRATION METHODS
WO2020232247A1 (en) 2019-05-14 2020-11-19 Provention Bio, Inc. Methods and compositions for preventing type 1 diabetes
JP2023551559A (ja) * 2020-12-04 2023-12-08 モルフォシス・アーゲー 抗cd19併用療法
JP2024506831A (ja) 2021-01-28 2024-02-15 リジェネロン・ファーマシューティカルズ・インコーポレイテッド サイトカイン放出症候群を治療するための組成物及び方法
WO2023201226A1 (en) 2022-04-11 2023-10-19 Regeneron Pharmaceuticals, Inc. Compositions and methods for universal tumor cell killing

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE243754T1 (de) 1987-05-21 2003-07-15 Micromet Ag Multifunktionelle proteine mit vorbestimmter zielsetzung
JP4169478B2 (ja) 1998-04-21 2008-10-22 マイクロメット アーゲー Cd19×cd3特異的ポリペプチドおよびその使用
CA2522586C (en) 2003-05-31 2017-02-21 Micromet Ag Pharmaceutical compositions comprising bispecific anti-cd3, anti-cd19 antibody constructs for the treatment of b-cell related disorders
EP2186527A1 (en) 2003-11-28 2010-05-19 Micromet AG Compositions comprising polypeptides
HUE025945T2 (en) 2005-02-15 2016-07-28 Univ Duke Anti-CD19 antibodies and their applications in oncology
WO2006114115A1 (de) * 2005-04-26 2006-11-02 Trion Pharma Gmbh Kombination von antikörpern mit glukokortikoiden zur behandlung von krebs
CN101331151A (zh) * 2005-12-16 2008-12-24 麦克罗梅特股份公司 ***性疾病的方式和方法
EP1976886B1 (en) * 2005-12-16 2014-12-17 Amgen Research (Munich) GmbH Means and methods for the treatment of tumorous diseases
KR101456728B1 (ko) 2006-09-08 2014-10-31 메디뮨 엘엘씨 인간화 항-cd19 항체, 및 이것의 종양학, 이식 및 자가면역 질환의 치료에서의 용도
AU2008234020B2 (en) 2007-04-03 2013-02-07 Amgen Research (Munich) Gmbh Cross-species-specific CD3-epsilon binding domain
ME02363B (me) * 2008-11-07 2016-06-20 Amgen Res Munich Gmbh Liječenje akutne limfoblastične leukemije
HUE025759T2 (en) 2009-10-27 2016-04-28 Amgen Res (Munich) Gmbh Dosage system for administering CD19xCD3 bispecific antibody
PT2632954E (pt) * 2010-10-27 2016-02-03 Amgen Res Munich Gmbh Meios e métodos para tratar dlbcl

Also Published As

Publication number Publication date
HUE037786T2 (hu) 2018-09-28
EP3018145B1 (en) 2018-04-04
EP3412687A1 (en) 2018-12-12
HRP20180882T1 (hr) 2018-07-27
KR101889995B1 (ko) 2018-08-20
EP2632954A1 (en) 2013-09-04
MY163057A (en) 2017-08-15
SMT201600050B (it) 2016-04-29
CY1117155T1 (el) 2017-04-05
JP2016164192A (ja) 2016-09-08
IL260774B (en) 2019-02-28
CY1120227T1 (el) 2018-12-12
CN103459425B (zh) 2015-11-25
SI2632954T2 (sl) 2021-11-30
AU2011322581B2 (en) 2015-04-23
NZ701715A (en) 2016-05-27
EP3412687B1 (en) 2020-03-18
TR201808019T4 (tr) 2018-06-21
JP6254220B2 (ja) 2017-12-27
HK1188229A1 (en) 2014-04-25
SI2632954T1 (sl) 2016-02-29
DK3412687T3 (da) 2020-05-11
EA201390387A1 (ru) 2013-10-30
SG189869A1 (en) 2013-06-28
CN105251003A (zh) 2016-01-20
US10696744B2 (en) 2020-06-30
AU2011322581A1 (en) 2013-05-09
HRP20151444T4 (hr) 2021-08-20
PL2632954T3 (pl) 2016-05-31
PT3018145T (pt) 2018-05-17
PL3018145T3 (pl) 2018-09-28
CR20130245A (es) 2013-09-20
US20130287778A1 (en) 2013-10-31
ES2675299T3 (es) 2018-07-10
UA111175C2 (uk) 2016-04-11
PT3412687T (pt) 2020-04-03
HUE048639T2 (hu) 2020-08-28
PL2632954T5 (pl) 2021-11-02
ME02311B (me) 2016-06-20
SI3018145T1 (en) 2018-08-31
KR20140019298A (ko) 2014-02-14
CL2013001138A1 (es) 2014-11-14
CN103459425A (zh) 2013-12-18
CN105251003B (zh) 2019-08-02
RS60094B1 (sr) 2020-05-29
RS54525B2 (sr) 2021-08-31
WO2012055961A1 (en) 2012-05-03
EA032139B1 (ru) 2019-04-30
RS54525B1 (en) 2016-06-30
DK2632954T4 (da) 2021-08-09
CA2815119A1 (en) 2012-05-03
RS57260B1 (sr) 2018-08-31
SI3412687T1 (sl) 2020-07-31
IL256110B (en) 2018-08-30
IL256110A (en) 2018-02-28
IL225924A0 (en) 2013-06-27
ES2563439T3 (es) 2016-03-15
EP2632954B2 (en) 2021-07-07
CY1123251T1 (el) 2021-10-29
PL3412687T3 (pl) 2020-07-27
NZ719768A (en) 2021-07-30
PT2632954E (pt) 2016-02-03
LT3018145T (lt) 2018-05-10
CA2815119C (en) 2023-01-10
JP2013540799A (ja) 2013-11-07
US20160208001A1 (en) 2016-07-21
US9192665B2 (en) 2015-11-24
JP5997168B2 (ja) 2016-09-28
NZ609201A (en) 2015-01-30
DK3018145T3 (en) 2018-05-28
IL225924A (en) 2017-12-31
ES2563439T5 (es) 2022-02-04
HUE027678T2 (en) 2016-11-28
ES2787044T3 (es) 2020-10-14
EP3018145A1 (en) 2016-05-11
MA34619B1 (fr) 2013-10-02
LT3412687T (lt) 2020-07-27
JP6522722B2 (ja) 2019-05-29
EP2632954B1 (en) 2015-11-25
DK2632954T3 (en) 2016-02-01
JP2018039838A (ja) 2018-03-15

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