HRP20070582T3 - Method for preparing para-phenyl alkynyl benzaldehydes - Google Patents
Method for preparing para-phenyl alkynyl benzaldehydesInfo
- Publication number
- HRP20070582T3 HRP20070582T3 HR20070582T HRP20070582T HRP20070582T3 HR P20070582 T3 HRP20070582 T3 HR P20070582T3 HR 20070582 T HR20070582 T HR 20070582T HR P20070582 T HRP20070582 T HR P20070582T HR P20070582 T3 HRP20070582 T3 HR P20070582T3
- Authority
- HR
- Croatia
- Prior art keywords
- compound
- formula
- alkyl
- heteroaryl
- aryl
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 3
- 150000001875 compounds Chemical class 0.000 abstract 8
- 125000004400 (C1-C12) alkyl group Chemical group 0.000 abstract 3
- 125000006710 (C2-C12) alkenyl group Chemical group 0.000 abstract 3
- 125000006711 (C2-C12) alkynyl group Chemical group 0.000 abstract 2
- 238000006243 chemical reaction Methods 0.000 abstract 2
- 239000003795 chemical substances by application Substances 0.000 abstract 2
- 125000006552 (C3-C8) cycloalkyl group Chemical group 0.000 abstract 1
- 150000001263 acyl chlorides Chemical class 0.000 abstract 1
- 150000004996 alkyl benzenes Chemical class 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 238000003379 elimination reaction Methods 0.000 abstract 1
- 150000004820 halides Chemical class 0.000 abstract 1
- 230000002140 halogenating effect Effects 0.000 abstract 1
- 125000001072 heteroaryl group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
- C07C49/84—Ketones containing a keto group bound to a six-membered aromatic ring containing ether groups, groups, groups, or groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C17/00—Preparation of halogenated hydrocarbons
- C07C17/093—Preparation of halogenated hydrocarbons by replacement by halogens
- C07C17/18—Preparation of halogenated hydrocarbons by replacement by halogens of oxygen atoms of carbonyl groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C17/00—Preparation of halogenated hydrocarbons
- C07C17/25—Preparation of halogenated hydrocarbons by splitting-off hydrogen halides from halogenated hydrocarbons
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C25/00—Compounds containing at least one halogen atom bound to a six-membered aromatic ring
- C07C25/24—Halogenated aromatic hydrocarbons with unsaturated side chains
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/004—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reaction with organometalhalides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/45—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by condensation
- C07C45/46—Friedel-Crafts reactions
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/56—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds
- C07C45/562—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds with nitrogen as the only hetero atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C47/00—Compounds having —CHO groups
- C07C47/52—Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings
- C07C47/548—Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings having unsaturation outside the six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C47/00—Compounds having —CHO groups
- C07C47/52—Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings
- C07C47/55—Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings containing halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C47/00—Compounds having —CHO groups
- C07C47/52—Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings
- C07C47/575—Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings containing ether groups, groups, groups, or groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
- C07C49/80—Ketones containing a keto group bound to a six-membered aromatic ring containing halogen
- C07C49/813—Ketones containing a keto group bound to a six-membered aromatic ring containing halogen polycyclic
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Abstract
Postupak za pripravu spojeva formule (I): naznačen time da jeR C1-C12-alkil, C1-C12-alkil aril, C1-C12-alkil heteroaril, C2-C12-aikenil, C2-C12-alkenil aril, C2-C12-alkenil heteroaril, C2-C12-alkinil, C2-C12-alkinil aril, C2-C12-alkinil heteroaril, C1-C12-alkil-C3-C8-cikloalkil, C3-C8-cikloalkil, C1-C12-aloksi skupina; aril, heteroaril, halidi; navedeni proces sadrži korake: korak 1: reakcija acil klorida formule (III) s alkil benzenom formule (IV) da se dobije odgovarajući spoj (V): u čemu je OS odlazna skupina; korak 2: pretvorba spoja formule (V) u spoj formule (VI) uporabom pogodnog sredstva za halogeniranje: korak 3: podvrgavanje spoja (VI) reakciji eliminacije da se dobije spoj formule (VII): korak 4: podvrgavanje spoja (VII) ili njegova aktiviranog oblika reakciji s formilirajućim agensom (VIII) da se dobije spoj (I): Patent sadrži još 7 patentnih zahtjeva.Process for the preparation of compounds of formula (I): wherein R is C1-C12-alkyl, C1-C12-alkyl aryl, C1-C12-alkyl heteroaryl, C2-C12-alkenyl, C2-C12-alkenyl aryl, C2-C12- alkenyl heteroaryl, C2-C12-alkynyl, C2-C12-alkynyl aryl, C2-C12-alkynyl heteroaryl, C1-C12-alkyl-C3-C8-cycloalkyl, C3-C8-cycloalkyl, C1-C12-alloxy group; aryl, heteroaryl, halides; said process comprising the steps of: step 1: reacting an acyl chloride of formula (III) with an alkyl benzene of formula (IV) to give the corresponding compound (V): wherein OS is a leaving group; step 2: conversion of the compound of formula (V) into a compound of formula (VI) using a suitable halogenating agent: step 3: subjecting the compound (VI) to an elimination reaction to give a compound of formula (VII): step 4: subjecting the compound (VII) or its of the activated form by reaction with a formylating agent (VIII) to give compound (I): The patent contains 7 more claims.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP03103780 | 2003-10-13 | ||
PCT/EP2004/052515 WO2005037758A1 (en) | 2003-10-13 | 2004-10-12 | Method for preparing para-phenyl alkynyl benzaldehydes |
Publications (1)
Publication Number | Publication Date |
---|---|
HRP20070582T3 true HRP20070582T3 (en) | 2008-01-31 |
Family
ID=34443013
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HR20070582T HRP20070582T3 (en) | 2003-10-13 | 2007-12-27 | Method for preparing para-phenyl alkynyl benzaldehydes |
Country Status (16)
Country | Link |
---|---|
US (1) | US7479575B2 (en) |
EP (1) | EP1675813B1 (en) |
JP (1) | JP4625009B2 (en) |
AT (1) | ATE381529T1 (en) |
AU (1) | AU2004281985B2 (en) |
CA (1) | CA2539155C (en) |
CY (1) | CY1107863T1 (en) |
DE (1) | DE602004010833T2 (en) |
DK (1) | DK1675813T3 (en) |
ES (1) | ES2295943T3 (en) |
HR (1) | HRP20070582T3 (en) |
IL (1) | IL175022A (en) |
NO (1) | NO20062163L (en) |
PL (1) | PL1675813T3 (en) |
PT (1) | PT1675813E (en) |
WO (1) | WO2005037758A1 (en) |
Families Citing this family (25)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7838708B2 (en) | 2001-06-20 | 2010-11-23 | Grt, Inc. | Hydrocarbon conversion process improvements |
US20050171393A1 (en) | 2003-07-15 | 2005-08-04 | Lorkovic Ivan M. | Hydrocarbon synthesis |
WO2005021468A1 (en) | 2003-07-15 | 2005-03-10 | Grt, Inc. | Hydrocarbon synthesis |
US20080275284A1 (en) | 2004-04-16 | 2008-11-06 | Marathon Oil Company | Process for converting gaseous alkanes to liquid hydrocarbons |
US20060100469A1 (en) | 2004-04-16 | 2006-05-11 | Waycuilis John J | Process for converting gaseous alkanes to olefins and liquid hydrocarbons |
US7674941B2 (en) | 2004-04-16 | 2010-03-09 | Marathon Gtf Technology, Ltd. | Processes for converting gaseous alkanes to liquid hydrocarbons |
US8173851B2 (en) | 2004-04-16 | 2012-05-08 | Marathon Gtf Technology, Ltd. | Processes for converting gaseous alkanes to liquid hydrocarbons |
US8642822B2 (en) | 2004-04-16 | 2014-02-04 | Marathon Gtf Technology, Ltd. | Processes for converting gaseous alkanes to liquid hydrocarbons using microchannel reactor |
US7244867B2 (en) | 2004-04-16 | 2007-07-17 | Marathon Oil Company | Process for converting gaseous alkanes to liquid hydrocarbons |
WO2007044270A1 (en) * | 2005-10-06 | 2007-04-19 | Albemarle Corporation | Process for producing high purity ketones by friedel-crafts acylation at low temperature |
EP1993979A4 (en) | 2006-02-03 | 2011-07-06 | Grt Inc | Continuous process for converting natural gas to liquid hydrocarbons |
UA95943C2 (en) | 2006-02-03 | 2011-09-26 | ДжиАрТи, ИНК. | Separation of light gases from halogens |
EA017699B1 (en) | 2007-05-24 | 2013-02-28 | Грт, Инк. | Zone reactor incorporating reversible hydrogen halide capture and release |
US8282810B2 (en) | 2008-06-13 | 2012-10-09 | Marathon Gtf Technology, Ltd. | Bromine-based method and system for converting gaseous alkanes to liquid hydrocarbons using electrolysis for bromine recovery |
SG192538A1 (en) | 2008-07-18 | 2013-08-30 | Grt Inc | Continuous process for converting natural gas to liquid hydrocarbons |
US8198495B2 (en) | 2010-03-02 | 2012-06-12 | Marathon Gtf Technology, Ltd. | Processes and systems for the staged synthesis of alkyl bromides |
US8367884B2 (en) | 2010-03-02 | 2013-02-05 | Marathon Gtf Technology, Ltd. | Processes and systems for the staged synthesis of alkyl bromides |
CN103153962A (en) | 2010-09-29 | 2013-06-12 | 纳幕尔杜邦公司 | Fungicidal imidazoles |
US8815050B2 (en) | 2011-03-22 | 2014-08-26 | Marathon Gtf Technology, Ltd. | Processes and systems for drying liquid bromine |
US8436220B2 (en) | 2011-06-10 | 2013-05-07 | Marathon Gtf Technology, Ltd. | Processes and systems for demethanization of brominated hydrocarbons |
US8829256B2 (en) | 2011-06-30 | 2014-09-09 | Gtc Technology Us, Llc | Processes and systems for fractionation of brominated hydrocarbons in the conversion of natural gas to liquid hydrocarbons |
US8802908B2 (en) | 2011-10-21 | 2014-08-12 | Marathon Gtf Technology, Ltd. | Processes and systems for separate, parallel methane and higher alkanes' bromination |
US9193641B2 (en) | 2011-12-16 | 2015-11-24 | Gtc Technology Us, Llc | Processes and systems for conversion of alkyl bromides to higher molecular weight hydrocarbons in circulating catalyst reactor-regenerator systems |
EP3010908A1 (en) | 2013-02-20 | 2016-04-27 | E. I. du Pont de Nemours and Company | Fungicidal pyrazoles |
CN103420823B (en) * | 2013-07-19 | 2016-06-08 | 南京欧信医药技术有限公司 | The synthetic method of ��-chloro-4 fluorophenyl benzyl ketones |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
HU172938B (en) * | 1976-05-25 | 1979-01-28 | Chinoin Gyogyszer Es Vegyeszet | Process for producing substituted phenyl-acethylenes |
JPH07138196A (en) * | 1993-11-19 | 1995-05-30 | Takeda Chem Ind Ltd | Trifluoromethyl-substituted vinyl compound, its production, liquid crystal composition containing the same compound and liquid crystal light-modulating apparatus using the same composition |
EA012260B1 (en) | 2002-01-29 | 2009-08-28 | Лаборатуар Сероно Са | Substituted methylene amide derivatives as modulators of protein tyrosine phosphatases (ptps) |
-
2004
- 2004-10-12 PL PL04791207T patent/PL1675813T3/en unknown
- 2004-10-12 JP JP2006530287A patent/JP4625009B2/en not_active Expired - Fee Related
- 2004-10-12 AU AU2004281985A patent/AU2004281985B2/en not_active Ceased
- 2004-10-12 DE DE602004010833T patent/DE602004010833T2/en active Active
- 2004-10-12 WO PCT/EP2004/052515 patent/WO2005037758A1/en active IP Right Grant
- 2004-10-12 ES ES04791207T patent/ES2295943T3/en active Active
- 2004-10-12 US US10/575,266 patent/US7479575B2/en not_active Expired - Fee Related
- 2004-10-12 DK DK04791207T patent/DK1675813T3/en active
- 2004-10-12 EP EP04791207A patent/EP1675813B1/en active Active
- 2004-10-12 AT AT04791207T patent/ATE381529T1/en active
- 2004-10-12 PT PT04791207T patent/PT1675813E/en unknown
- 2004-10-12 CA CA2539155A patent/CA2539155C/en not_active Expired - Fee Related
-
2006
- 2006-04-20 IL IL175022A patent/IL175022A/en not_active IP Right Cessation
- 2006-05-12 NO NO20062163A patent/NO20062163L/en not_active Application Discontinuation
-
2007
- 2007-12-27 HR HR20070582T patent/HRP20070582T3/en unknown
-
2008
- 2008-01-18 CY CY20081100081T patent/CY1107863T1/en unknown
Also Published As
Publication number | Publication date |
---|---|
AU2004281985B2 (en) | 2010-09-16 |
US20080108849A1 (en) | 2008-05-08 |
PT1675813E (en) | 2008-01-10 |
DK1675813T3 (en) | 2008-03-03 |
JP4625009B2 (en) | 2011-02-02 |
DE602004010833T2 (en) | 2009-01-08 |
CA2539155C (en) | 2012-08-07 |
EP1675813A1 (en) | 2006-07-05 |
CA2539155A1 (en) | 2005-04-28 |
CY1107863T1 (en) | 2012-05-23 |
ES2295943T3 (en) | 2008-04-16 |
US7479575B2 (en) | 2009-01-20 |
IL175022A0 (en) | 2006-08-20 |
IL175022A (en) | 2010-12-30 |
AU2004281985A1 (en) | 2005-04-28 |
WO2005037758A1 (en) | 2005-04-28 |
EP1675813B1 (en) | 2007-12-19 |
DE602004010833D1 (en) | 2008-01-31 |
JP2007508277A (en) | 2007-04-05 |
NO20062163L (en) | 2006-06-26 |
ATE381529T1 (en) | 2008-01-15 |
PL1675813T3 (en) | 2008-05-30 |
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