HN2009001067A - DIAZEPAN REPLACER ANTAGONISTS REPLACED - Google Patents

DIAZEPAN REPLACER ANTAGONISTS REPLACED

Info

Publication number
HN2009001067A
HN2009001067A HN2009001067A HN2009001067A HN2009001067A HN 2009001067 A HN2009001067 A HN 2009001067A HN 2009001067 A HN2009001067 A HN 2009001067A HN 2009001067 A HN2009001067 A HN 2009001067A HN 2009001067 A HN2009001067 A HN 2009001067A
Authority
HN
Honduras
Prior art keywords
antagonists
diazepan
replacer
replaced
compounds
Prior art date
Application number
HN2009001067A
Other languages
Spanish (es)
Inventor
Bergman Jeffrey
J Breslin Michael
J Coleman Paul
D Cox Christopher
P Mercer Swati
J Roecker Anthony
Original Assignee
Merck Sharp & Dohme
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Sharp & Dohme filed Critical Merck Sharp & Dohme
Publication of HN2009001067A publication Critical patent/HN2009001067A/en

Links

Landscapes

  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

LA PRESENTE INVENCION ESTA DIRIGIDA A COMPUESTOS DE DIAZEPAN SUSTITUIDOS QUE SON ANTAGONISTAS DE RECEPTORES DE OREXINA Y QUE SON UTILES EN EL TRATAMIENTO O LA PREVENCION DE TRASTORNOS O ENFERMEDADES NEUROLOGICAS Y PSIQUIATRICOS EN LOS QUE ESTAN IMPLICADOS LOS RECEPTORES DE OREXINA. LA INVENCION ESTA TAMBIEN DIRIGIDA A COMPOSICIONES FARMACEUTICAS QUE COMPRENDEN ESTOS COMPUESTOS Y AL USO DE ESTOS COMPUESTOS Y COMPOSICIONES EN LA PREVENCION O EL TRATAMIENTO DE DICHAS ENFERMEDADES EN LAS QUE ESTAN IMPLICADOS RECEPTORES DE OREXINATHE PRESENT INVENTION IS AIMED AT SUBSTITUTED DIAZEPAN COMPOUNDS THAT ARE ANTAGONISTS OF OREXIN RECEPTORS AND THAT ARE USEFUL IN THE TREATMENT OR PREVENTION OF NEUROLOGICAL AND PSYCHIATRIC DISORDERS OR IN WHICH THEY ARE INVOLVED OR RECEPTED. THE INVENTION IS ALSO AIMED AT PHARMACEUTICAL COMPOSITIONS THAT INCLUDE THESE COMPOUNDS AND THE USE OF THESE COMPOUNDS AND COMPOSITIONS IN THE PREVENTION OR TREATMENT OF SUCH DISEASES IN WHICH OREXINE RECEPTORS ARE INVOLVED

HN2009001067A 2006-12-01 2009-05-26 DIAZEPAN REPLACER ANTAGONISTS REPLACED HN2009001067A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US87239306P 2006-12-01 2006-12-01

Publications (1)

Publication Number Publication Date
HN2009001067A true HN2009001067A (en) 2011-05-11

Family

ID=41522310

Family Applications (1)

Application Number Title Priority Date Filing Date
HN2009001067A HN2009001067A (en) 2006-12-01 2009-05-26 DIAZEPAN REPLACER ANTAGONISTS REPLACED

Country Status (4)

Country Link
CN (1) CN101627028B (en)
HN (1) HN2009001067A (en)
UA (2) UA100974C2 (en)
ZA (1) ZA200903334B (en)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2890949A1 (en) * 2012-11-12 2014-05-15 Dr. Reddy's Laboratories Limited Polymorphic forms of suvorexant
CN103012293A (en) * 2012-12-13 2013-04-03 同济大学 Synthetic method for anti-sleeplessness medicine MK-4305 intermediate
CN103923068B (en) * 2014-02-13 2016-09-07 武汉珈瑜科技有限公司 For compound preparing suvorexant and preparation method thereof
CN105377840B (en) * 2014-05-28 2017-12-22 杭州普晒医药科技有限公司 The salt and its crystal formation and amorphous article of a kind of diazepan compounds
WO2016020405A1 (en) * 2014-08-04 2016-02-11 Sandoz Ag Novel routes of synthesis for the preparation of suvorexant
CN105461699B (en) * 2014-09-25 2019-07-09 广东东阳光药业有限公司 Substituted heterocyclic compound and its application method and purposes
CN104327061A (en) * 2014-10-19 2015-02-04 湖南华腾制药有限公司 Preparation method of bromobenzo[d]oxazole derivative
CN104649983B (en) * 2014-12-23 2018-01-23 广东东阳光药业有限公司 A kind of sour preparation method
AU2016295693B2 (en) * 2015-07-17 2020-05-21 Sunshine Lake Pharma Co., Ltd. Substituted quinazoline compounds and preparation and uses thereof
AU2016360245B2 (en) * 2015-11-23 2020-07-09 Sunshine Lake Pharma Co., Ltd. Octahydropyrrolo [3, 4-c] pyrrole derivatives and uses thereof
CN106916149A (en) * 2015-12-25 2017-07-04 上海奥博生物医药技术有限公司 A kind of method for preparing Su Woleisheng
CN107021964A (en) * 2016-02-01 2017-08-08 广东东阳光药业有限公司 7-naphthyridine derivatives and application thereof
CN105949203B (en) * 2016-05-24 2018-07-13 广东东阳光药业有限公司 Octahydro pyrrolo- [3,4-c] azole derivatives and its application method and purposes
CN106866632A (en) * 2017-01-19 2017-06-20 成都美域高制药有限公司 A kind of method for preparing Suvorexant intermediates and the like
CN109942563A (en) * 2017-12-21 2019-06-28 上海医药工业研究院 A kind of preparation method of Su Woleisheng midbody compound
CN111943945B (en) * 2020-09-03 2022-07-12 上海应用技术大学 Suvorexant intermediate and preparation method thereof

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS536156B2 (en) * 1972-10-30 1978-03-04
AU3578595A (en) * 1994-11-25 1996-06-19 Nippon Chemiphar Co. Ltd. Quinazoline derivative
JP4563387B2 (en) * 2003-09-09 2010-10-13 エフ．ホフマン−ラ ロシュ アーゲー 1-Benzoyl-piperazine derivatives as glycine uptake inhibitors for the treatment of psychosis

Also Published As

Publication number Publication date
UA106873C2 (en) 2014-10-27
ZA200903334B (en) 2010-04-28
CN101627028A (en) 2010-01-13
UA100974C2 (en) 2013-02-25
CN101627028B (en) 2013-03-27

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