HK1259372A1 - 治療化合物、其組合物及使用方法 - Google Patents

治療化合物、其組合物及使用方法

Info

Publication number
HK1259372A1
HK1259372A1 HK19101740.0A HK19101740A HK1259372A1 HK 1259372 A1 HK1259372 A1 HK 1259372A1 HK 19101740 A HK19101740 A HK 19101740A HK 1259372 A1 HK1259372 A1 HK 1259372A1
Authority
HK
Hong Kong
Prior art keywords
compositions
methods
therapeutic compounds
therapeutic
compounds
Prior art date
Application number
HK19101740.0A
Other languages
English (en)
Inventor
Paul Gibbons
Terry Kellar
Mark Zak
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of HK1259372A1 publication Critical patent/HK1259372A1/zh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
HK19101740.0A 2016-02-18 2019-01-31 治療化合物、其組合物及使用方法 HK1259372A1 (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201662297061P 2016-02-18 2016-02-18
PCT/EP2017/053576 WO2017140825A1 (en) 2016-02-18 2017-02-17 Therapeutic compounds, compositions and methods of use thereof

Publications (1)

Publication Number Publication Date
HK1259372A1 true HK1259372A1 (zh) 2019-11-29

Family

ID=58054137

Family Applications (1)

Application Number Title Priority Date Filing Date
HK19101740.0A HK1259372A1 (zh) 2016-02-18 2019-01-31 治療化合物、其組合物及使用方法

Country Status (6)

Country Link
US (2) US20180354959A1 (zh)
EP (1) EP3416967B1 (zh)
JP (1) JP6936236B2 (zh)
CN (1) CN108473501B (zh)
HK (1) HK1259372A1 (zh)
WO (1) WO2017140825A1 (zh)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2015342887B2 (en) 2014-11-06 2020-09-10 Bial - R&D Investments, S.A. Substituted pyrazolo(1,5-a)pyrimidines and their use in the treatment of medical disorders
MX2018012211A (es) 2016-04-06 2019-03-28 Lysosomal Therapeutics Inc Compuestos de pirazol[1,5-a]pirimidinil carboxamida y su uso en el tratamiento de trastornos médicos.
JP7034935B2 (ja) 2016-04-06 2022-03-14 リソソーマル・セラピューティクス・インコーポレイテッド ピロロ［１，２－ａ］ピリミジニルカルボキサミド化合物および医学的障害の処置におけるその使用
WO2017176961A1 (en) 2016-04-06 2017-10-12 Lysosomal Therapeutics Inc. Imidazo [1,5-a]pyrimidinyl carboxamide compounds and their use in the treatment of medical disorders
CN109311902B (zh) 2016-05-05 2022-07-15 Bial研发投资股份有限公司 取代的咪唑并[1,2-b]哒嗪、咪唑并[1,5-b]哒嗪、相关化合物及其用途
MX2019007339A (es) 2016-12-29 2019-09-06 Hoffmann La Roche Compuestos de pirazolopirimidina y metodos de uso de los mismos.
WO2018166993A2 (en) * 2017-03-14 2018-09-20 F. Hoffmann-La Roche Ag Pyrazolochlorophenyl compounds, compositions and methods of use thereof
TW201902896A (zh) 2017-05-22 2019-01-16 瑞士商赫孚孟拉羅股份公司 治療化合物及組合物及其使用方法
JP7228318B6 (ja) * 2017-05-22 2023-03-10 エフ． ホフマン－ラ ロシュ アーゲー 処置用化合物及び組成物、並びにその使用方法
EP3986901A1 (en) * 2019-06-18 2022-04-27 F. Hoffmann-La Roche AG Pyrazolopyrimidine sulfone inhibitors of jak kinases and uses thereof

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5512665B2 (ja) 2008-06-20 2014-06-04 ジェネンテック， インコーポレイテッド トリアゾロピリジンｊａｋ阻害剤化合物と方法
UA110324C2 (en) 2009-07-02 2015-12-25 Genentech Inc Jak inhibitory compounds based on pyrazolo pyrimidine
US8575336B2 (en) 2011-07-27 2013-11-05 Pfizer Limited Indazoles
ES2666353T3 (es) * 2012-09-06 2018-05-04 Bristol-Myers Squibb Company Inhibidores de JAK3 de imidazopiridazina y su uso para el tratamiento de enfermedades inflamatorias y autoinmunitarias
BR112016010041B1 (pt) * 2013-11-08 2023-04-18 Takeda Pharmaceutical Company Limited Composto heterocíclico com uma ação inibitória de irak-4, composição farmacêutica, e, uso do composto
SI3145929T1 (sl) * 2014-05-23 2021-10-29 Hoffmann La Roche 5-kloro-2-difluorometoksifenil pirazolopirimidinove spojine, ki so zaviralci janusove kinaze

Also Published As

Publication number Publication date
EP3416967A1 (en) 2018-12-26
US20210009599A1 (en) 2021-01-14
WO2017140825A1 (en) 2017-08-24
EP3416967B1 (en) 2022-02-09
CN108473501A (zh) 2018-08-31
JP2019505529A (ja) 2019-02-28
US11795170B2 (en) 2023-10-24
CN108473501B (zh) 2021-07-16
JP6936236B2 (ja) 2021-09-15
US20180354959A1 (en) 2018-12-13

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