HK1256304A1 - 用於生成單克隆抗體的方法和試劑 - Google Patents
用於生成單克隆抗體的方法和試劑Info
- Publication number
- HK1256304A1 HK1256304A1 HK18115369.1A HK18115369A HK1256304A1 HK 1256304 A1 HK1256304 A1 HK 1256304A1 HK 18115369 A HK18115369 A HK 18115369A HK 1256304 A1 HK1256304 A1 HK 1256304A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- reagents
- methods
- monoclonal antibodies
- creating monoclonal
- creating
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
- C07K16/081—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from DNA viruses
- C07K16/082—Hepadnaviridae, e.g. hepatitis B virus
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/44—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material not provided for elsewhere, e.g. haptens, metals, DNA, RNA, amino acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161450922P | 2011-03-09 | 2011-03-09 | |
| US201161560006P | 2011-11-15 | 2011-11-15 | |
| US201161566876P | 2011-12-05 | 2011-12-05 | |
| US201261594729P | 2012-02-03 | 2012-02-03 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HK1256304A1 true HK1256304A1 (zh) | 2019-09-20 |
Family
ID=45922811
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HK18115369.1A HK1256304A1 (zh) | 2011-03-09 | 2018-11-30 | 用於生成單克隆抗體的方法和試劑 |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US9920110B2 (zh) |
| EP (2) | EP2683736B1 (zh) |
| JP (3) | JP6211931B2 (zh) |
| KR (3) | KR101938343B1 (zh) |
| CN (2) | CN103842379A (zh) |
| AU (3) | AU2012225310B2 (zh) |
| CA (1) | CA2829606C (zh) |
| DK (1) | DK2683736T3 (zh) |
| ES (1) | ES2666301T3 (zh) |
| HK (1) | HK1256304A1 (zh) |
| HU (1) | HUE037095T2 (zh) |
| WO (1) | WO2012122484A1 (zh) |
Families Citing this family (46)
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| DK3059337T3 (da) | 2009-01-15 | 2019-07-22 | Adaptive Biotechnologies Corp | Adaptive immunity profiling og metoder til frembringelse af monoklonale antibodier |
| EP2783214A2 (en) | 2011-11-23 | 2014-10-01 | The Board of Regents of The University of Texas System | Proteomic identification of antibodies |
| EP2823060B1 (en) | 2012-03-05 | 2018-02-14 | Adaptive Biotechnologies Corporation | Determining paired immune receptor chains from frequency matched subunits |
| JP5756247B1 (ja) | 2012-05-08 | 2015-07-29 | アダプティブ バイオテクノロジーズ コーポレイション | マルチプレックスｐｃｒ反応における増幅バイアスを測定し校正する組成物及び方法 |
| CA2875695C (en) | 2012-06-15 | 2022-11-15 | The Board Of Regents Of The University Of Texas System | High throughput sequencing of multiple transcripts of a single cell |
| US10150996B2 (en) | 2012-10-19 | 2018-12-11 | Adaptive Biotechnologies Corp. | Quantification of adaptive immune cell genomes in a complex mixture of cells |
| US20160024493A1 (en) * | 2013-03-15 | 2016-01-28 | Adaptive Biotechnologies Corporation | Uniquely tagged rearranged adaptive immune receptor genes in a complex gene set |
| US9708657B2 (en) | 2013-07-01 | 2017-07-18 | Adaptive Biotechnologies Corp. | Method for generating clonotype profiles using sequence tags |
| US10208125B2 (en) | 2013-07-15 | 2019-02-19 | University of Pittsburgh—of the Commonwealth System of Higher Education | Anti-mucin 1 binding agents and uses thereof |
| JP5924455B2 (ja) * | 2013-09-09 | 2016-05-25 | 株式会社島津製作所 | ペプチド断片の調製方法およびそれに用いられるペプチド断片調製用キット、ならびに分析方法 |
| GB201316644D0 (en) * | 2013-09-19 | 2013-11-06 | Kymab Ltd | Expression vector production & High-Throughput cell screening |
| US10066265B2 (en) | 2014-04-01 | 2018-09-04 | Adaptive Biotechnologies Corp. | Determining antigen-specific t-cells |
| WO2015200626A1 (en) * | 2014-06-25 | 2015-12-30 | The Rockefeller University | Compositions and methods for rapid production of versatile nanobody repertoires |
| CN105277638A (zh) * | 2014-07-22 | 2016-01-27 | 沈鹤霄 | 一种单克隆抗体IgG质谱测序方法 |
| WO2016069886A1 (en) | 2014-10-29 | 2016-05-06 | Adaptive Biotechnologies Corporation | Highly-multiplexed simultaneous detection of nucleic acids encoding paired adaptive immune receptor heterodimers from many samples |
| US10246701B2 (en) | 2014-11-14 | 2019-04-02 | Adaptive Biotechnologies Corp. | Multiplexed digital quantitation of rearranged lymphoid receptors in a complex mixture |
| CN104560979B (zh) * | 2015-01-20 | 2017-04-05 | 中国人民解放军第三军医大学 | 基于高通量测序构建鼠bcr重链文库的多重pcr引物和方法 |
| CN104560980B (zh) * | 2015-01-20 | 2017-04-05 | 中国人民解放军第三军医大学 | 基于高通量测序构建鼠BCR轻链Lamda文库的多重PCR引物和方法 |
| WO2016138122A1 (en) | 2015-02-24 | 2016-09-01 | Adaptive Biotechnologies Corp. | Methods for diagnosing infectious disease and determining hla status using immune repertoire sequencing |
| CN107646089B (zh) | 2015-03-06 | 2020-12-08 | 英国质谱公司 | 光谱分析 |
| EP3265820B1 (en) | 2015-03-06 | 2023-12-13 | Micromass UK Limited | Spectrometric analysis of microbes |
| EP3726562B1 (en) | 2015-03-06 | 2023-12-20 | Micromass UK Limited | Ambient ionization mass spectrometry imaging platform for direct mapping from bulk tissue |
| CN108700590B (zh) | 2015-03-06 | 2021-03-02 | 英国质谱公司 | 细胞群体分析 |
| KR102092047B1 (ko) | 2015-03-06 | 2020-03-24 | 마이크로매스 유케이 리미티드 | 생체내 내시경 조직 식별 도구 |
| US11289320B2 (en) | 2015-03-06 | 2022-03-29 | Micromass Uk Limited | Tissue analysis by mass spectrometry or ion mobility spectrometry |
| US10026599B2 (en) * | 2015-03-06 | 2018-07-17 | Micromass Uk Limited | Rapid evaporative ionisation mass spectrometry (“REIMS”) and desorption electrospray ionisation mass spectrometry (“DESI-MS”) analysis of swabs and biopsy samples |
| US10513733B2 (en) | 2015-03-23 | 2019-12-24 | Board Of Regents, The University Of Texas System | High throughout sequencing of paired VH and VL transcripts from B cells secreting antigen-specific antibodies |
| AU2016242967B2 (en) | 2015-04-01 | 2021-07-01 | Adaptive Biotechnologies Corp. | Method of identifying human compatible T cell receptors specific for an antigenic target |
| EP3346912A4 (en) * | 2015-09-09 | 2019-08-21 | Ubiome Inc. | METHOD AND SYSTEM FOR MICROBIAL-DERIVED DIAGNOSTICS AND THERAPEUTIC FOR DISEASES RELATED TO CEREBRO-KRANIOFAZIAL HEALTH |
| US11454611B2 (en) | 2016-04-14 | 2022-09-27 | Micromass Uk Limited | Spectrometric analysis of plants |
| CN106047857B (zh) * | 2016-06-01 | 2020-04-03 | 苏州金唯智生物科技有限公司 | 一种发掘特异性功能抗体的方法 |
| CN107525934A (zh) * | 2016-06-21 | 2017-12-29 | 张效龙 | 一种测定血液中抗体氨基酸序列的方法 |
| US10428325B1 (en) | 2016-09-21 | 2019-10-01 | Adaptive Biotechnologies Corporation | Identification of antigen-specific B cell receptors |
| WO2018162376A1 (en) * | 2017-03-07 | 2018-09-13 | F. Hoffmann-La Roche Ag | Method for discovery of alternative antigen specific antibody variants |
| WO2019016411A1 (en) * | 2017-07-21 | 2019-01-24 | Novimmune Sa | GENERATION OF MULTISPECIFIC ANTIBODY MIXTURES AND METHODS OF USE |
| CN109425662A (zh) * | 2017-08-23 | 2019-03-05 | 深圳华大基因研究院 | 一种鉴定蛋白的方法及*** |
| WO2019084538A1 (en) | 2017-10-27 | 2019-05-02 | Board Of Regents, The University Of Texas System | TUMOR SPECIFIC ANTIBODIES, T CELL RECEPTORS AND METHODS OF IDENTIFICATION THEREOF |
| US11254980B1 (en) | 2017-11-29 | 2022-02-22 | Adaptive Biotechnologies Corporation | Methods of profiling targeted polynucleotides while mitigating sequencing depth requirements |
| EP3769083A1 (en) | 2018-03-21 | 2021-01-27 | Waters Technologies Corporation | Non-antibody high-affinity-based sample preparation, sorbents, devices and methods |
| JP2020514681A (ja) * | 2018-03-29 | 2020-05-21 | 深▲セン▼▲達▼▲闥▼科技控股有限公司Ｃｌｏｕｄｍｉｎｄｓ （Ｓｈｅｎｚｈｅｎ） Ｈｏｌｄｉｎｇｓ Ｃｏ．， Ｌｔｄ． | 物質検出方法、装置、電子機器、およびコンピュータ可読記憶媒体 |
| CN108530533B (zh) * | 2018-04-13 | 2020-09-04 | 吉林大学 | 猪瘟病毒单克隆抗体hk24及医用用途 |
| EP3894867A4 (en) * | 2018-12-11 | 2022-09-28 | Merck Sharp & Dohme Corp. | PROCEDURE FOR IDENTIFICATION OF HIGH-AFFINITY MONOCLONAL ANTIBODIES OF HEAVY AND LIGHT CHAIN FROM HIGH-THROUGHPUT SCREENS OF B-CELL AND HYBRIDOME LIBRARIES |
| CN110452296A (zh) * | 2019-07-16 | 2019-11-15 | 福州精锐生物技术有限公司 | 一种兔单克隆抗体制备方法 |
| WO2022216795A1 (en) * | 2021-04-09 | 2022-10-13 | Abterra Biosciences, Inc. | Method for antibody identification from protein mixtures |
| IT202100019334A1 (it) * | 2021-07-21 | 2023-01-21 | Univ Degli Studi Di Pavia | Metodo per l’identificazione dell’intera sequenza della regione variabile delle catene pesanti e leggere di immunoglobuline |
| CN115894687A (zh) * | 2022-03-31 | 2023-04-04 | 台州恩泽医疗中心(集团) | 一种抗hla-g1，-g2，-g5及hla-g6异构体分子的单克隆抗体及其用途 |
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-
2012
- 2012-03-09 ES ES12711501.2T patent/ES2666301T3/es active Active
- 2012-03-09 JP JP2013557906A patent/JP6211931B2/ja active Active
- 2012-03-09 KR KR1020137026647A patent/KR101938343B1/ko active IP Right Grant
- 2012-03-09 EP EP12711501.2A patent/EP2683736B1/en active Active
- 2012-03-09 WO PCT/US2012/028501 patent/WO2012122484A1/en unknown
- 2012-03-09 CN CN201280021326.1A patent/CN103842379A/zh active Pending
- 2012-03-09 KR KR1020197000660A patent/KR20190006083A/ko not_active Application Discontinuation
- 2012-03-09 HU HUE12711501A patent/HUE037095T2/hu unknown
- 2012-03-09 CA CA2829606A patent/CA2829606C/en active Active
- 2012-03-09 AU AU2012225310A patent/AU2012225310B2/en active Active
- 2012-03-09 US US13/416,582 patent/US9920110B2/en active Active
- 2012-03-09 KR KR1020197026655A patent/KR20190107761A/ko not_active Application Discontinuation
- 2012-03-09 EP EP17196465.3A patent/EP3345922A1/en not_active Withdrawn
- 2012-03-09 DK DK12711501.2T patent/DK2683736T3/en active
- 2012-03-09 CN CN201810154961.6A patent/CN108220297A/zh active Pending
-
2017
- 2017-09-13 JP JP2017175320A patent/JP6557709B2/ja not_active Expired - Fee Related
- 2017-10-12 AU AU2017245395A patent/AU2017245395B2/en active Active
-
2018
- 2018-01-19 US US15/875,615 patent/US20190002532A1/en not_active Abandoned
- 2018-11-30 HK HK18115369.1A patent/HK1256304A1/zh unknown
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2019
- 2019-07-11 JP JP2019128863A patent/JP2019195335A/ja active Pending
- 2019-08-14 AU AU2019216660A patent/AU2019216660A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| EP2683736A1 (en) | 2014-01-15 |
| US20120308555A1 (en) | 2012-12-06 |
| US9920110B2 (en) | 2018-03-20 |
| CN103842379A (zh) | 2014-06-04 |
| KR20190006083A (ko) | 2019-01-16 |
| ES2666301T3 (es) | 2018-05-03 |
| AU2012225310B2 (en) | 2017-08-03 |
| CA2829606A1 (en) | 2012-09-13 |
| JP2018027090A (ja) | 2018-02-22 |
| KR20140010436A (ko) | 2014-01-24 |
| JP6557709B2 (ja) | 2019-08-07 |
| WO2012122484A1 (en) | 2012-09-13 |
| CA2829606C (en) | 2020-06-02 |
| AU2017245395B2 (en) | 2019-05-16 |
| JP6211931B2 (ja) | 2017-10-11 |
| EP3345922A1 (en) | 2018-07-11 |
| AU2017245395A2 (en) | 2017-11-23 |
| JP2019195335A (ja) | 2019-11-14 |
| AU2017245395A1 (en) | 2017-11-02 |
| JP2014509853A (ja) | 2014-04-24 |
| CN108220297A (zh) | 2018-06-29 |
| KR20190107761A (ko) | 2019-09-20 |
| US20190002532A1 (en) | 2019-01-03 |
| AU2012225310A1 (en) | 2013-09-26 |
| AU2019216660A1 (en) | 2019-09-05 |
| KR101938343B1 (ko) | 2019-01-14 |
| HUE037095T2 (hu) | 2018-08-28 |
| EP2683736B1 (en) | 2018-01-17 |
| DK2683736T3 (en) | 2018-04-23 |
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