HK1246360A1 - Method and kit for super-high-sensitivity measurement of protein and nucleic acid, and novel enzyme substrate - Google Patents

Method and kit for super-high-sensitivity measurement of protein and nucleic acid, and novel enzyme substrate

Info

Publication number
HK1246360A1
HK1246360A1 HK18105590.3A HK18105590A HK1246360A1 HK 1246360 A1 HK1246360 A1 HK 1246360A1 HK 18105590 A HK18105590 A HK 18105590A HK 1246360 A1 HK1246360 A1 HK 1246360A1
Authority
HK
Hong Kong
Prior art keywords
super
kit
protein
nucleic acid
enzyme substrate
Prior art date
Application number
HK18105590.3A
Other languages
Chinese (zh)
Inventor
Etsuro Ito
Original Assignee
Etsuro Ito
Watabe Satoshi
Miura Toshiaki
Yoshimura Teruki
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Etsuro Ito, Watabe Satoshi, Miura Toshiaki, Yoshimura Teruki filed Critical Etsuro Ito
Publication of HK1246360A1 publication Critical patent/HK1246360A1/en

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G01N21/77—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
    • G01N21/78—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator producing a change of colour
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/008—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions for determining co-enzymes or co-factors, e.g. NAD, ATP
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/26—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase
    • C12Q1/28—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase involving peroxidase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
    • C12Q1/42—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving phosphatase
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/25—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/902—Oxidoreductases (1.)
    • G01N2333/90209—Oxidoreductases (1.) acting on NADH or NADPH (1.6), e.g. those with a heme protein as acceptor (1.6.2) (general), Cytochrome-b5 reductase (1.6.2.2) or NADPH-cytochrome P450 reductase (1.6.2.4)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/914—Hydrolases (3)
    • G01N2333/916—Hydrolases (3) acting on ester bonds (3.1), e.g. phosphatases (3.1.3), phospholipases C or phospholipases D (3.1.4)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/914—Hydrolases (3)
    • G01N2333/924—Hydrolases (3) acting on glycosyl compounds (3.2)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Plasma & Fusion (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
HK18105590.3A 2011-03-23 2018-04-30 Method and kit for super-high-sensitivity measurement of protein and nucleic acid, and novel enzyme substrate HK1246360A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2011063559 2011-03-23

Publications (1)

Publication Number Publication Date
HK1246360A1 true HK1246360A1 (en) 2018-09-07

Family

ID=46879477

Family Applications (2)

Application Number Title Priority Date Filing Date
HK16109783.4A HK1221743A1 (en) 2011-03-23 2016-08-16 Method and kit for super-high-sensitivity measurement of protein and nucleic acid, and novel enzyme substrate
HK18105590.3A HK1246360A1 (en) 2011-03-23 2018-04-30 Method and kit for super-high-sensitivity measurement of protein and nucleic acid, and novel enzyme substrate

Family Applications Before (1)

Application Number Title Priority Date Filing Date
HK16109783.4A HK1221743A1 (en) 2011-03-23 2016-08-16 Method and kit for super-high-sensitivity measurement of protein and nucleic acid, and novel enzyme substrate

Country Status (6)

Country Link
US (2) US9851309B2 (en)
EP (3) EP2987866B1 (en)
JP (1) JP5265816B2 (en)
ES (3) ES2657986T3 (en)
HK (2) HK1221743A1 (en)
WO (1) WO2012128338A1 (en)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3572417A3 (en) 2011-10-14 2020-03-25 Sage Therapeutics, Inc. 3,3 disubstituted 19-nor pregnane compounds, compositions, and uses thereof
TR201808616T4 (en) 2012-12-18 2018-07-23 Sage Therapeutics Inc Neuroactive 19-alkoxy-17-substituted steroids, their prodrugs and methods of treatment using them.
JP2014124165A (en) * 2012-12-27 2014-07-07 Bl:Kk High-sensitivity measuring method and kit of protein and nucleic acid, and enzyme composition
WO2014169836A1 (en) 2013-04-17 2014-10-23 Sage Therapeutics, Inc. 19-nor neuroactive steroids and methods of use thereof
PL2986624T3 (en) 2013-04-17 2020-11-16 Sage Therapeutics, Inc. 19-nor neuroactive steroids for methods of treatment
US9512165B2 (en) 2013-04-17 2016-12-06 Sage Therapeutics, Inc. 19-nor C3, 3-disubstituted C21-N-pyrazolyl steroids and methods of use thereof
US9725481B2 (en) 2013-04-17 2017-08-08 Sage Therapeutics, Inc. 19-nor C3, 3-disubstituted C21-C-bound heteroaryl steroids and methods of use thereof
CA2918735C (en) 2013-07-19 2023-08-01 Sage Therapeutics, Inc. Neuroactive steroids, compositions, and uses thereof
EP3035940B1 (en) 2013-08-23 2018-10-17 Sage Therapeutics, Inc. Neuroactive steroids, compositions, and uses thereof
WO2015195962A1 (en) 2014-06-18 2015-12-23 Sage Therapeutics, Inc. Neuroactive steroids, compositions, and uses thereof
NZ769042A (en) 2014-10-16 2023-12-22 Sage Therapeutics Inc Compositions and methods for treating cns disorders
CN117024501A (en) 2014-10-16 2023-11-10 萨奇治疗股份有限公司 Compositions and methods for targeting CNS disorders
PT3224269T (en) 2014-11-27 2020-06-01 Sage Therapeutics Inc Compositions and methods for treating cns disorders
SI3250210T1 (en) 2015-01-26 2021-07-30 Sage Therapeutics, Inc. Compositions and methods for treating cns disorders
WO2016134301A2 (en) 2015-02-20 2016-08-25 Sage Therapeutics, Inc. Neuroactive steroids, compositions, and uses thereof
JP6960210B2 (en) 2016-03-30 2021-11-05 悦朗 伊藤 Ultra-sensitive measurement method for proteins and nucleic acids
AU2017296295B2 (en) 2016-07-11 2022-02-24 Sage Therapeutics, Inc. C7, C12, and C16 substituted neuroactive steroids and their methods of use
CN109689673B (en) 2016-07-11 2023-03-14 萨奇治疗股份有限公司 C17, C20 and C21 substituted neuroactive steroids and methods of use thereof
BR112021024033A2 (en) 2019-05-31 2022-02-08 Sage Therapeutics Inc Neuroactive steroids and their compositions

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR83554E (en) 1961-07-21 1964-09-04 Roussel Uclaf Process for the preparation of etiocholane derivatives
US6011023A (en) * 1997-08-27 2000-01-04 Alcon Laboratories, Inc. Angiostatic steroids
JP5500985B2 (en) * 2007-03-28 2014-05-21 悦朗 伊藤 Ultrasensitive measurement method of protein and nucleic acid
JP4904298B2 (en) * 2008-03-03 2012-03-28 学校法人村崎学園 徳島文理大学 Method for measuring steroid 5α-reductase activity and kit used therefor
JP6960210B2 (en) * 2016-03-30 2021-11-05 悦朗 伊藤 Ultra-sensitive measurement method for proteins and nucleic acids

Also Published As

Publication number Publication date
ES2613619T3 (en) 2017-05-24
EP3296405B1 (en) 2019-10-09
EP2695948A1 (en) 2014-02-12
EP2695948A4 (en) 2015-04-08
US9851309B2 (en) 2017-12-26
JP5265816B2 (en) 2013-08-14
EP2987866A3 (en) 2016-06-15
ES2657986T3 (en) 2018-03-07
HK1221743A1 (en) 2017-06-09
EP3296405A1 (en) 2018-03-21
JPWO2012128338A1 (en) 2014-07-24
EP2987866A2 (en) 2016-02-24
WO2012128338A1 (en) 2012-09-27
EP2695948B1 (en) 2016-12-28
US20180106727A1 (en) 2018-04-19
EP2987866B1 (en) 2017-12-06
US20140017675A1 (en) 2014-01-16
ES2762098T3 (en) 2020-05-22
US11221299B2 (en) 2022-01-11

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