HK1245139A1 - 用於在局部給藥位點改進藥物組合物的滯留的組合物和方法 - Google Patents

用於在局部給藥位點改進藥物組合物的滯留的組合物和方法

Info

Publication number
HK1245139A1
HK1245139A1 HK18104837.9A HK18104837A HK1245139A1 HK 1245139 A1 HK1245139 A1 HK 1245139A1 HK 18104837 A HK18104837 A HK 18104837A HK 1245139 A1 HK1245139 A1 HK 1245139A1
Authority
HK
Hong Kong
Prior art keywords
compositions
methods
pharmaceutical composition
local administration
administration site
Prior art date
Application number
HK18104837.9A
Other languages
English (en)
Inventor
T‧R‧泰斯
K‧W‧伯頓
Original Assignee
贏創有限公司
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 贏創有限公司 filed Critical 贏創有限公司
Publication of HK1245139A1 publication Critical patent/HK1245139A1/zh

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1629Organic macromolecular compounds
    • A61K9/1641Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
    • A61K9/1647Polyesters, e.g. poly(lactide-co-glycolide)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0085Brain, e.g. brain implants; Spinal cord
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1629Organic macromolecular compounds
    • A61K9/1652Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S260/00Chemistry of carbon compounds
    • Y10S260/31Ionic cross-link

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Dermatology (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
HK18104837.9A 2010-03-29 2018-05-16 用於在局部給藥位點改進藥物組合物的滯留的組合物和方法 HK1245139A1 (zh)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US31857410P 2010-03-29 2010-03-29

Publications (1)

Publication Number Publication Date
HK1245139A1 true HK1245139A1 (zh) 2018-08-24

Family

ID=44080321

Family Applications (1)

Application Number Title Priority Date Filing Date
HK18104837.9A HK1245139A1 (zh) 2010-03-29 2018-05-16 用於在局部給藥位點改進藥物組合物的滯留的組合物和方法

Country Status (11)

Country Link
US (1) US9504643B2 (zh)
EP (1) EP2552416B1 (zh)
JP (2) JP2013523752A (zh)
CN (2) CN103068371A (zh)
AU (1) AU2011238646B2 (zh)
CA (1) CA2794328C (zh)
ES (1) ES2655592T3 (zh)
HK (1) HK1245139A1 (zh)
IL (1) IL222092B (zh)
RU (1) RU2012145811A (zh)
WO (1) WO2011126839A2 (zh)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10092524B2 (en) 2008-06-11 2018-10-09 Edge Therapeutics, Inc. Compositions and their use to treat complications of aneurysmal subarachnoid hemorrhage
US20120321665A1 (en) * 2009-12-14 2012-12-20 Benaroya Research Institute At Virginia Mason Compositions and methods for treating airway inflammatory diseases
GB2513675A (en) 2011-04-05 2014-11-05 Edge Therapeutics Intraventricular drug delivery system for improving outcome after a brain injury affecting cerebral blood flow
US9399019B2 (en) 2012-05-09 2016-07-26 Evonik Corporation Polymorph compositions, methods of making, and uses thereof
DE102015220583A1 (de) * 2015-10-21 2017-04-27 Tetec Tissue Engineering Technologies Ag Medizinische Zusammensetzung und medizinisches Hydrogel zur Anwendung bei der Vorbeugung und/oder Behandlung einer Erkrankung der Facettengelenke und/oder zur Anwendung beim Ersatz und/oder der Regeneration von Facettengelenkknorpel
WO2018079812A1 (ja) 2016-10-31 2018-05-03 キユーピー株式会社 ゲル組成物及びその製造方法
AU2018240375C1 (en) 2017-03-22 2024-02-01 Ascendis Pharma A/S Hydrogel cross-linked hyaluronic acid prodrug compositions and methods
WO2019050977A1 (en) 2017-09-05 2019-03-14 Torque Therapeutics, Inc. REVERSIBLE LINKS AND THEIR USE
CA3074826A1 (en) 2017-09-05 2019-03-14 Torque Therapeutics, Inc. Therapeutic protein compositions and methods of making and using the same

Family Cites Families (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1476088A (en) * 1975-04-03 1977-06-10 Ici Ltd Carbodiimides
US5324519A (en) * 1989-07-24 1994-06-28 Atrix Laboratories, Inc. Biodegradable polymer composition
JP3283288B2 (ja) * 1991-03-08 2002-05-20 電気化学工業株式会社 生理活性ペプチド製剤
GR920100122A (el) 1991-04-05 1993-03-16 Ethicon Inc Πολυσακχαρίτες οι οποίοι περιέχουν καρβοξύλιο με σταυροειδείς δεσμούς δια την πρόληψιν της προσφύσεως.
US6150581A (en) * 1995-06-07 2000-11-21 United States Surgical Corporation Chitosan/alginate anti-adhesion barrier
JP3898783B2 (ja) * 1996-08-26 2007-03-28 久光製薬株式会社 生体内分解性ヒアルロン酸架橋ゲル組成物及び生体内分解性ヒアルロン酸架橋ゲル製剤
EP1028746B1 (en) * 1997-11-07 2003-02-26 Chiron Corporation Method for producing igf-i sustained-release formulations
US6630457B1 (en) 1998-09-18 2003-10-07 Orthogene Llc Functionalized derivatives of hyaluronic acid, formation of hydrogels in situ using same, and methods for making and using same
US6899889B1 (en) * 1998-11-06 2005-05-31 Neomend, Inc. Biocompatible material composition adaptable to diverse therapeutic indications
GB9902652D0 (en) 1999-02-05 1999-03-31 Fermentech Med Ltd Process
US6352667B1 (en) 1999-08-24 2002-03-05 Absorbable Polymer Technologies, Inc. Method of making biodegradable polymeric implants
US6458387B1 (en) * 1999-10-18 2002-10-01 Epic Therapeutics, Inc. Sustained release microspheres
WO2001047501A1 (en) 1999-12-29 2001-07-05 Nanodelivery, Inc. Drug delivery system exhibiting permeability control
CN1259343C (zh) 2000-02-03 2006-06-14 电气化学工业株式会社 透明质酸凝胶、其制造方法以及含有它的医用材料
ATE425776T1 (de) 2000-04-28 2009-04-15 Fziomed Inc Haemostatische zusammenstellung von polysauren und polyalkylenoxyden und deren verwendungsmethoden
US7008633B2 (en) * 2000-12-18 2006-03-07 Board Of Regents, The University Of Texas System Local regional chemotherapy and radiotherapy using in situ hydrogel
TW200307011A (en) 2002-04-18 2003-12-01 Chugai Pharmaceutical Co Ltd Hyaluronic acid modifier
EP1545461A4 (en) * 2002-09-09 2011-06-22 Endo Pharmaceuticals Inc COMBINED ANALGESIC COMPOSITION WITH IMMEDIATE AND PROLONGED RELEASE
WO2004042068A2 (en) * 2002-10-31 2004-05-21 Northwestern University Injectable and bioadhesive polymeric hydrogels as well as related methods of enzymatic preparation
US7601704B2 (en) 2003-11-03 2009-10-13 University Of North Texas Process for synthesizing oil and surfactant-free hyaluronic acid nanoparticles and microparticles
US20070224278A1 (en) 2003-11-12 2007-09-27 Lyons Robert T Low immunogenicity corticosteroid compositions
US7976858B2 (en) * 2004-01-13 2011-07-12 The Hospital For Special Surgery Drug delivery to a joint
WO2006036681A2 (en) * 2004-09-22 2006-04-06 Cartilix, Inc. Cartilage filling device
MX2007004261A (es) 2004-10-12 2007-06-18 Fmc Biopolymer As Sistemas de alginato auto-gelificantes y usos de los mismos.
JP2008517927A (ja) * 2004-10-21 2008-05-29 ユニバーシティー オブ アイオワ リサーチ ファンデーション insitu制御放出薬剤送達システム
US8303972B2 (en) * 2005-04-19 2012-11-06 Advanced Cardiovascular Systems, Inc. Hydrogel bioscaffoldings and biomedical device coatings
ITPI20050071A1 (it) * 2005-06-20 2006-12-21 Giuseppe Calvosa Composizione biocompatibile per la sostituzione/rigenerazione di tessuti
US20070141160A1 (en) 2005-12-15 2007-06-21 Brown Laura J Method of treatment for osteoarthritis by local intra-articular injection of microparticles
WO2007084460A2 (en) * 2006-01-18 2007-07-26 Qps, Llc Pharmaceutical compositions with enhanced stability
US20080069857A1 (en) * 2006-04-12 2008-03-20 Yoon Yeo Compositions And Methods For Inhibiting Adhesions
JP2010505819A (ja) 2006-10-05 2010-02-25 パナセア バイオテック リミテッド デポ型注射剤組成物とその調製方法

Also Published As

Publication number Publication date
CA2794328A1 (en) 2011-10-13
IL222092B (en) 2019-02-28
ES2655592T3 (es) 2018-02-20
EP2552416A2 (en) 2013-02-06
CN103068371A (zh) 2013-04-24
CN107260684A (zh) 2017-10-20
WO2011126839A3 (en) 2012-05-03
US20110236497A1 (en) 2011-09-29
JP2016011312A (ja) 2016-01-21
JP6203224B2 (ja) 2017-09-27
JP2013523752A (ja) 2013-06-17
US9504643B2 (en) 2016-11-29
WO2011126839A2 (en) 2011-10-13
AU2011238646A1 (en) 2012-10-11
RU2012145811A (ru) 2014-05-10
EP2552416B1 (en) 2017-10-25
AU2011238646B2 (en) 2016-02-04
CA2794328C (en) 2018-01-16

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