HK1223858A1 - 用於評估蛋白質的特性和穩定性的方法 - Google Patents

用於評估蛋白質的特性和穩定性的方法

Info

Publication number
HK1223858A1
HK1223858A1 HK16112336.0A HK16112336A HK1223858A1 HK 1223858 A1 HK1223858 A1 HK 1223858A1 HK 16112336 A HK16112336 A HK 16112336A HK 1223858 A1 HK1223858 A1 HK 1223858A1
Authority
HK
Hong Kong
Prior art keywords
stability
protein identity
assessing protein
assessing
identity
Prior art date
Application number
HK16112336.0A
Other languages
English (en)
Inventor
John Brian Mumm
Vlasselaer Peter Van
Original Assignee
Armo Biosciences Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Armo Biosciences Inc filed Critical Armo Biosciences Inc
Publication of HK1223858A1 publication Critical patent/HK1223858A1/zh

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6863—Cytokines, i.e. immune system proteins modifying a biological response such as cell growth proliferation or differentiation, e.g. TNF, CNF, GM-CSF, lymphotoxin, MIF or their receptors
    • G01N33/6869—Interleukin
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6848—Methods of protein analysis involving mass spectrometry
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6848—Methods of protein analysis involving mass spectrometry
    • G01N33/6851—Methods of protein analysis involving laser desorption ionisation mass spectrometry
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/88—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86
    • G01N2030/8809—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86 analysis specially adapted for the sample
    • G01N2030/8813—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86 analysis specially adapted for the sample biological materials
    • G01N2030/8831—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86 analysis specially adapted for the sample biological materials involving peptides or proteins
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/52—Assays involving cytokines
    • G01N2333/54—Interleukins [IL]
    • G01N2333/5428—IL-10
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2496/00—Reference solutions for assays of biological material
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2560/00—Chemical aspects of mass spectrometric analysis of biological material
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/416—Systems
    • G01N27/447—Systems using electrophoresis
HK16112336.0A 2013-06-17 2016-10-27 用於評估蛋白質的特性和穩定性的方法 HK1223858A1 (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201361836034P 2013-06-17 2013-06-17
PCT/US2014/042399 WO2014204816A2 (en) 2013-06-17 2014-06-13 Method for assessing protein identity and stability

Publications (1)

Publication Number Publication Date
HK1223858A1 true HK1223858A1 (zh) 2017-08-11

Family

ID=52105481

Family Applications (1)

Application Number Title Priority Date Filing Date
HK16112336.0A HK1223858A1 (zh) 2013-06-17 2016-10-27 用於評估蛋白質的特性和穩定性的方法

Country Status (8)

Country Link
US (2) US9823255B2 (zh)
EP (2) EP3434277A1 (zh)
JP (1) JP2016528879A (zh)
AU (1) AU2014281828B2 (zh)
CA (1) CA2914837A1 (zh)
ES (1) ES2688206T3 (zh)
HK (1) HK1223858A1 (zh)
WO (1) WO2014204816A2 (zh)

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CA2914837A1 (en) 2013-06-17 2014-12-24 Armo Biosciences, Inc. Method for assessing protein identity and stability
US10010588B2 (en) * 2013-08-30 2018-07-03 Armo Biosciences, Inc. Methods of using pegylated interleukin-10 for treating hyperlipidemia
WO2015070060A1 (en) 2013-11-11 2015-05-14 Armo Biosciences, Inc. Methods of using interleukin-10 for treating diseases and disorders
CN106573072A (zh) 2014-06-02 2017-04-19 阿尔莫生物科技股份有限公司 降低血清胆固醇的方法
CN107106655A (zh) 2014-10-22 2017-08-29 阿尔莫生物科技股份有限公司 使用白细胞介素‑10治疗疾病和病症的方法
WO2016126615A1 (en) 2015-02-03 2016-08-11 Armo Biosciences, Inc. Methods of using interleukin-10 for treating diseases and disorders
EP3302547A1 (en) 2015-05-28 2018-04-11 Armo Biosciences, Inc. Pegylated interleukin-10 for use in treating cancer
CN104931637B (zh) * 2015-06-25 2017-03-29 吉林大学 一种生物样本中peg含量的测定方法
AU2016312510A1 (en) 2015-08-25 2018-03-08 Armo Biosciences, Inc. Methods of using Interleukin-10 for treating diseases and disorders
US20190339286A1 (en) * 2016-12-20 2019-11-07 Treat4Life Ab Method to determine braf mutations and wild type braf protein by mass spectrometry
EP3864418A1 (en) * 2018-10-08 2021-08-18 Applied Photophysics Limited System and method for analysing the composition of a quenched flow reaction liquid
CN113366015A (zh) * 2018-10-19 2021-09-07 Ambrx公司 白细胞介素-10多肽缀合物、其二聚体及其用途
KR20210091170A (ko) * 2018-11-08 2021-07-21 신톡스, 인크. 인터류킨 10 접합체 및 이의 용도

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Publication number Publication date
WO2014204816A2 (en) 2014-12-24
US20160123991A1 (en) 2016-05-05
US10209261B2 (en) 2019-02-19
CA2914837A1 (en) 2014-12-24
AU2014281828A1 (en) 2016-01-07
US9823255B2 (en) 2017-11-21
EP3010527B1 (en) 2018-08-08
ES2688206T3 (es) 2018-10-31
EP3010527A4 (en) 2017-01-11
JP2016528879A (ja) 2016-09-23
AU2014281828B2 (en) 2019-05-09
US20180031570A1 (en) 2018-02-01
WO2014204816A3 (en) 2015-08-13
EP3010527A2 (en) 2016-04-27
EP3434277A1 (en) 2019-01-30

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