HK1217735A1 - 用於單分子分析的方法 - Google Patents

用於單分子分析的方法

Info

Publication number
HK1217735A1
HK1217735A1 HK16105786.9A HK16105786A HK1217735A1 HK 1217735 A1 HK1217735 A1 HK 1217735A1 HK 16105786 A HK16105786 A HK 16105786A HK 1217735 A1 HK1217735 A1 HK 1217735A1
Authority
HK
Hong Kong
Prior art keywords
methods
molecule analysis
molecule
analysis
Prior art date
Application number
HK16105786.9A
Other languages
English (en)
Inventor
曹涵
肖明
亞曆克斯.
.黑斯蒂
邁克爾.
.薩比尼
亨利.
.薩多夫斯基
Original Assignee
Bionano Genomics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bionano Genomics Inc filed Critical Bionano Genomics Inc
Publication of HK1217735A1 publication Critical patent/HK1217735A1/zh

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6809Methods for determination or identification of nucleic acids involving differential detection
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6869Methods for sequencing
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6806Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Analytical Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Genetics & Genomics (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
HK16105786.9A 2013-02-05 2016-05-20 用於單分子分析的方法 HK1217735A1 (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201361761189P 2013-02-05 2013-02-05
PCT/US2014/014501 WO2014123822A1 (en) 2013-02-05 2014-02-03 Methods for single-molecule analysis

Publications (1)

Publication Number Publication Date
HK1217735A1 true HK1217735A1 (zh) 2017-01-20

Family

ID=51259712

Family Applications (1)

Application Number Title Priority Date Filing Date
HK16105786.9A HK1217735A1 (zh) 2013-02-05 2016-05-20 用於單分子分析的方法

Country Status (8)

Country Link
US (2) US20140221218A1 (zh)
EP (1) EP2954069B1 (zh)
JP (1) JP6475171B2 (zh)
CN (1) CN105143462A (zh)
AU (2) AU2014215586A1 (zh)
CA (1) CA2900054A1 (zh)
HK (1) HK1217735A1 (zh)
WO (1) WO2014123822A1 (zh)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2007338862B2 (en) 2006-07-19 2014-02-06 Bionano Genomics, Inc. Nanonozzle device arrays: their preparation and use for macromolecular analysis
EP2136922B1 (en) 2007-03-28 2012-12-05 BioNano Genomics, Inc. Methods of macromolecular analysis using nanochannel arrays
JP5730762B2 (ja) 2008-06-30 2015-06-10 バイオナノ ジェノミックス、インク. 単一分子全ゲノム解析のための方法及び装置
AU2009316628B2 (en) 2008-11-18 2016-06-16 Bionano Genomics, Inc. Polynucleotide mapping and sequencing
US10844424B2 (en) 2013-02-20 2020-11-24 Bionano Genomics, Inc. Reduction of bias in genomic coverage measurements
WO2015130696A1 (en) 2014-02-25 2015-09-03 Bionano Genomics, Inc. Reduction of bias in genomic coverage measurements
CN105229168B (zh) 2013-02-20 2020-07-17 生物纳米基因有限公司 纳米流体中分子的表征
WO2015126840A1 (en) * 2014-02-18 2015-08-27 Bionano Genomics, Inc. Improved methods of determining nucleic acid structural information
EP3497239A4 (en) * 2016-08-10 2020-02-26 Ramot at Tel-Aviv University Ltd. METHYLATION STATUS ANALYSIS AND COPY NUMBER
EP3662079A4 (en) * 2017-07-31 2021-04-14 Technion Research & Development Foundation Limited METHODS OF DETECTION OF MODIFIED AND NON-MODIFIED DNA
WO2019099081A1 (en) * 2017-11-16 2019-05-23 New England Biolabs, Inc. Mapping the location, type and strand of damaged and/or mismatched nucleotides in double-stranded dna
US11180796B2 (en) 2018-06-13 2021-11-23 International Business Machines Corporation Detection of mutations regarding one or more deoxyribonucleic acid sequences using deterministic lateral displacement arrays
US11149298B2 (en) 2018-06-13 2021-10-19 International Business Machines Corporation Detection of nucleic acid sequences using deterministic lateral displacement arrays
JP2023530751A (ja) 2020-06-25 2023-07-19 ペルセウス バイオミクス サンプル中のウイルスを特徴付けるためのキット及び方法

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US4521509A (en) * 1982-11-24 1985-06-04 Research Corporation Method for degrading DNA
US5736334A (en) * 1993-04-12 1998-04-07 Abbott Laboratories Nucleotide sequences and process for amplifying and detection of hepatitis B viral DNA
FR2716263B1 (fr) * 1994-02-11 1997-01-17 Pasteur Institut Procédé d'alignement de macromolécules par passage d'un ménisque et applications dans un procédé de mise en évidence, séparation et/ou dosage d'une macromolécule dans un échantillon.
US7270958B2 (en) * 1998-09-10 2007-09-18 The Regents Of The University Of Michigan Compositions and methods for analysis of nucleic acids
JP2005517382A (ja) * 2001-06-08 2005-06-16 ユー.エス. ジェノミクス, インコーポレイテッド ニックトランスレーションを使用する、核酸を分析するための方法および生成物
US6613523B2 (en) * 2001-06-29 2003-09-02 Agilent Technologies, Inc. Method of DNA sequencing using cleavable tags
WO2003055975A2 (en) * 2001-08-23 2003-07-10 New England Biolabs, Inc. A method for engineering strand-specific, sequence-specific, dna-nicking enzymes
US7393635B2 (en) * 2002-05-16 2008-07-01 Dna Polymerase Technology, Inc. Ribocloning: recombinant DNA construction using primers with ribo bases
US20050019784A1 (en) * 2002-05-20 2005-01-27 Xing Su Method and apparatus for nucleic acid sequencing and identification
US8158388B2 (en) * 2004-10-21 2012-04-17 New England Biolabs, Inc. Repair of nucleic acids for improved amplification
US7960105B2 (en) * 2005-11-29 2011-06-14 National Institutes Of Health Method of DNA analysis using micro/nanochannel
US20070148674A1 (en) * 2005-12-23 2007-06-28 Wisconsin Alumni Research Foundation (Warf) Optical fingerprinting of nucleic acid sequences
AU2007338862B2 (en) * 2006-07-19 2014-02-06 Bionano Genomics, Inc. Nanonozzle device arrays: their preparation and use for macromolecular analysis
US7862999B2 (en) * 2007-01-17 2011-01-04 Affymetrix, Inc. Multiplex targeted amplification using flap nuclease
EP2136922B1 (en) * 2007-03-28 2012-12-05 BioNano Genomics, Inc. Methods of macromolecular analysis using nanochannel arrays
US9689031B2 (en) * 2007-07-14 2017-06-27 Ionian Technologies, Inc. Nicking and extension amplification reaction for the exponential amplification of nucleic acids
US8951731B2 (en) * 2007-10-15 2015-02-10 Complete Genomics, Inc. Sequence analysis using decorated nucleic acids
US7771944B2 (en) * 2007-12-14 2010-08-10 The Board Of Trustees Of The University Of Illinois Methods for determining genetic haplotypes and DNA mapping
US9533879B2 (en) * 2008-06-02 2017-01-03 Bionano Genomics, Inc. Integrated analysis devices and related fabrication methods and analysis techniques
WO2011050147A1 (en) * 2009-10-21 2011-04-28 Bionanomatrix, Inc . Methods and related devices for single molecule whole genome analysis
JP5730762B2 (ja) * 2008-06-30 2015-06-10 バイオナノ ジェノミックス、インク. 単一分子全ゲノム解析のための方法及び装置
CN102150037B (zh) * 2008-07-11 2014-06-04 康奈尔大学 集成电荷传感器的纳米流体通道及基于该纳米流体通道的方法
US9597687B2 (en) * 2008-10-10 2017-03-21 Jonas Tegenfeldt Method for the mapping of the local AT/GC ratio along DNA
US8017328B2 (en) * 2008-11-21 2011-09-13 Agilent Technologies, Inc. Genome partitioning using a nicking endonuclease
US20100330557A1 (en) * 2009-06-30 2010-12-30 Zohar Yakhini Genomic coordinate system
US20100330556A1 (en) * 2009-06-30 2010-12-30 Brian Jon Peter Genome analysis using a nicking endonuclease
EP3940084A1 (en) * 2011-02-09 2022-01-19 Bio-Rad Laboratories, Inc. Analysis of nucleic acids
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WO2013019361A1 (en) * 2011-07-07 2013-02-07 Life Technologies Corporation Sequencing methods

Also Published As

Publication number Publication date
CA2900054A1 (en) 2014-08-14
EP2954069A1 (en) 2015-12-16
EP2954069A4 (en) 2016-09-14
US20150368706A1 (en) 2015-12-24
JP6475171B2 (ja) 2019-02-27
AU2020201280B2 (en) 2022-04-07
AU2014215586A1 (en) 2015-08-20
AU2020201280A1 (en) 2020-03-12
CN105143462A (zh) 2015-12-09
WO2014123822A1 (en) 2014-08-14
EP2954069B1 (en) 2020-11-11
JP2016507239A (ja) 2016-03-10
US20140221218A1 (en) 2014-08-07

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