HK1217433A1 - 使用含有槲皮素的組合物治療血栓性疾病的方法 - Google Patents

使用含有槲皮素的組合物治療血栓性疾病的方法

Info

Publication number
HK1217433A1
HK1217433A1 HK16105413.0A HK16105413A HK1217433A1 HK 1217433 A1 HK1217433 A1 HK 1217433A1 HK 16105413 A HK16105413 A HK 16105413A HK 1217433 A1 HK1217433 A1 HK 1217433A1
Authority
HK
Hong Kong
Prior art keywords
quercetin
containing compositions
thrombotic disorders
treating thrombotic
treating
Prior art date
Application number
HK16105413.0A
Other languages
English (en)
Inventor
托馬斯‧克里斯琴‧萊恩斯
Original Assignee
Quercegen Pharmaceuticals Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Quercegen Pharmaceuticals Llc filed Critical Quercegen Pharmaceuticals Llc
Publication of HK1217433A1 publication Critical patent/HK1217433A1/zh

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • A61K31/375—Ascorbic acid, i.e. vitamin C; Salts thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4365—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system having sulfur as a ring hetero atom, e.g. ticlopidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/455—Nicotinic acids, e.g. niacin; Derivatives thereof, e.g. esters, amides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
HK16105413.0A 2011-10-13 2016-05-11 使用含有槲皮素的組合物治療血栓性疾病的方法 HK1217433A1 (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US13/272,508 US10391096B2 (en) 2011-10-13 2011-10-13 Method for treating thrombotic disorders using quercetin-containing compositions
PCT/US2012/059341 WO2013055679A2 (en) 2011-10-13 2012-10-09 Method for treating thrombotic disorders using quercetin-containing compositions

Publications (1)

Publication Number Publication Date
HK1217433A1 true HK1217433A1 (zh) 2017-01-13

Family

ID=48082728

Family Applications (1)

Application Number Title Priority Date Filing Date
HK16105413.0A HK1217433A1 (zh) 2011-10-13 2016-05-11 使用含有槲皮素的組合物治療血栓性疾病的方法

Country Status (7)

Country Link
US (1) US10391096B2 (zh)
EP (2) EP3964208A1 (zh)
CN (1) CN105101961A (zh)
HK (1) HK1217433A1 (zh)
IN (1) IN2014MN00890A (zh)
RU (1) RU2642983C2 (zh)
WO (1) WO2013055679A2 (zh)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI671014B (zh) 2012-11-26 2019-09-11 美商通路實業集團國際公司 抗氧化膳食增補劑及其相關方法
CN104013964B (zh) * 2014-06-11 2016-08-17 深圳奥萨医药有限公司 含有口服抗凝药和b族维生素的药物组合物及其用途
CA3226825A1 (en) * 2014-06-19 2015-12-23 Quercis Pharma AG Method for treating cancer with a combination of quercetin and a chemotherapy agent
TWI761672B (zh) 2018-04-23 2022-04-21 日商阿爾卑斯藥品工業股份有限公司 O-醣苷基類黃酮之組成物
CN110711191B (zh) * 2018-07-12 2023-05-19 北京奇明达企业管理有限公司 华法林与维生素c的分子复合物,其制备,活性和应用
US11872241B2 (en) 2018-11-30 2024-01-16 Beth Israel Deaconess Medical Center, Inc. Compositions and methods for reducing major thrombotic events in cancer patients
US10617705B1 (en) * 2019-01-24 2020-04-14 Alps Pharmaceutical Ind. Co., Ltd. Isoquercitrin compositions
RU2762945C1 (ru) * 2021-03-02 2021-12-24 Федеральное Государственное Бюджетное Научное Учреждение "Федеральный Научно-Клинический Центр Реаниматологии И Реабилитологии" (Фнкц Рр) Способ антикоагулянтной терапии и профилактики тромботических осложнений у пациентов с тяжелым повреждением головного мозга в хроническом критическом состоянии
EP4370122A1 (en) * 2021-07-16 2024-05-22 Beth Israel Deaconess Medical Center, Inc. Method for treating sickle cell disease using quercetin-containing compositions
CN114767666B (zh) * 2022-03-31 2024-01-23 东北大学 柽柳黄素在制备预防或治疗缺血性脑病药物中的应用

Family Cites Families (19)

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DE69826253D1 (de) 1997-03-20 2004-10-21 Coventry Group Ltd Nährungsergänzungsmittel für kardiovasküläre gesundheit
US6121249A (en) * 1998-07-01 2000-09-19 Donald L. Weissman Treatment and prevention of cardiovascular diseases with help of aspirin, antioxidants, niacin, and certain B vitamins
JP2002523456A (ja) 1998-08-27 2002-07-30 メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフトング アスコルビン酸塩−イソケルセチン組成物
IT1302863B1 (it) 1998-11-13 2000-10-10 Sigma Tau Healthscience Spa Composizione ad attivita' antiossidante e preventiva di alterazionitrombotiche e aterosclerotiche comprendente una carnitina ed un
US20030100493A1 (en) * 2001-07-19 2003-05-29 Sol Weiss Sublingual use of inhibitors in the biosynthesis of cholesterol
US7485298B2 (en) * 2002-05-23 2009-02-03 Michael Powell Diagnosis and treatment of human dormancy-related sequellae
CN100350914C (zh) 2002-12-20 2007-11-28 沈阳华泰药物研究有限公司 解热、镇痛、抗炎、抗血小板聚集的药物组合物及其制备
CN1251693C (zh) 2004-03-17 2006-04-19 甘肃独一味生物制药有限责任公司 一种中西药复方制剂及其制备方法
CN1715277A (zh) * 2004-07-02 2006-01-04 车庆明 一种用于治疗心脑血管疾病的化合物及其制备方法和其在制药领域中的应用
WO2006076681A2 (en) * 2005-01-13 2006-07-20 Sirtris Pharmaceuticals, Inc. Novel compositions for preventing and treating neurodegenerative and blood coagulation disorders
WO2006084142A2 (en) * 2005-02-04 2006-08-10 The Scripps Research Institute Dyslipoproteinemia associated with venous thrombosis
CN1304017C (zh) 2005-05-12 2007-03-14 张兴惠 一种用于治疗脉管炎及血管栓塞性疾病的药物
US7887852B2 (en) * 2005-06-03 2011-02-15 Soft Gel Technologies, Inc. Soft gel capsules containing polymethoxylated flavones and palm oil tocotrienols
US20070248590A1 (en) * 2005-12-02 2007-10-25 Sirtris Pharmaceuticals, Inc. Modulators of CDC2-like kinases (CLKS) and methods of use thereof
CN100581552C (zh) * 2006-05-22 2010-01-20 吴建中 用于治疗心脑血管疾病的药物——复方葛根素
CN1895264B (zh) * 2006-06-16 2012-08-15 周亚球 槲皮素-3-O-β-D-葡萄糖苷的医药用途
US7745486B2 (en) 2006-07-17 2010-06-29 Quercegen Pharma Llc Quercetin-containing compositions
WO2008011364A2 (en) * 2006-07-17 2008-01-24 Thomas Christian Lines Quercetin-containing compositions
CN101554379B (zh) 2008-04-09 2011-04-13 鲁南制药集团股份有限公司 含有氯吡格雷的药物组合物

Also Published As

Publication number Publication date
RU2014118761A (ru) 2015-11-20
IN2014MN00890A (zh) 2015-04-17
CN105101961A (zh) 2015-11-25
RU2642983C2 (ru) 2018-01-29
WO2013055679A2 (en) 2013-04-18
US10391096B2 (en) 2019-08-27
EP2766013A2 (en) 2014-08-20
US20130095095A1 (en) 2013-04-18
EP2766013A4 (en) 2015-06-24
EP3964208A1 (en) 2022-03-09

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