HK1217201A1 - 種核苷類似物及其中間體的製備方法 - Google Patents

種核苷類似物及其中間體的製備方法

Info

Publication number
HK1217201A1
HK1217201A1 HK16105220.3A HK16105220A HK1217201A1 HK 1217201 A1 HK1217201 A1 HK 1217201A1 HK 16105220 A HK16105220 A HK 16105220A HK 1217201 A1 HK1217201 A1 HK 1217201A1
Authority
HK
Hong Kong
Prior art keywords
nucleoside analogue
preparing nucleoside
preparing
analogue
nucleoside
Prior art date
Application number
HK16105220.3A
Other languages
English (en)
Inventor
魏用剛
邱關鵬
盧泳華
祝國智
Original Assignee
Sichuan Haisco Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sichuan Haisco Pharmaceutical Co Ltd filed Critical Sichuan Haisco Pharmaceutical Co Ltd
Publication of HK1217201A1 publication Critical patent/HK1217201A1/zh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6561—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
HK16105220.3A 2014-04-21 2016-05-08 種核苷類似物及其中間體的製備方法 HK1217201A1 (zh)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
CN201410160622 2014-04-21
CN201410160634 2014-04-21
CN201410300520 2014-06-27
PCT/CN2015/077078 WO2015161781A1 (zh) 2014-04-21 2015-04-21 一种核苷类似物及其中间体的制备方法

Publications (1)

Publication Number Publication Date
HK1217201A1 true HK1217201A1 (zh) 2016-12-30

Family

ID=54331749

Family Applications (1)

Application Number Title Priority Date Filing Date
HK16105220.3A HK1217201A1 (zh) 2014-04-21 2016-05-08 種核苷類似物及其中間體的製備方法

Country Status (3)

Country Link
CN (2) CN105518011B (zh)
HK (1) HK1217201A1 (zh)
WO (2) WO2015161781A1 (zh)

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CN105518011B (zh) * 2014-04-21 2018-07-27 四川海思科制药有限公司 氨基磷酸酯类衍生物制备方法及其中间体和中间体的制备方法
CN105330700A (zh) * 2015-12-17 2016-02-17 中国药科大学 富马酸替诺福韦艾拉酚胺杂质的制备方法
EP3515923A1 (en) * 2016-09-23 2019-07-31 Katholieke Universiteit Leuven Prodrugs of fluorinated acyclic nucleoside phosphonates
CN106632484B (zh) * 2017-01-05 2020-06-12 上海厚璞生物科技有限公司 一种替诺福韦艾拉酚胺的制备方法
CN107021984B (zh) * 2017-04-28 2019-05-10 福建广生堂药业股份有限公司 一种taf核苷衍生物的制备方法及其中间体
CN107098936B (zh) * 2017-04-28 2020-09-08 福建广生堂药业股份有限公司 一种taf核苷衍生物的制备方法
CN107266499B (zh) * 2017-06-05 2019-07-02 珠海优润医药科技有限公司 一种抗病毒化合物及其制备方法
CN108409788B (zh) * 2018-03-12 2020-05-08 科兴生物制药股份有限公司 一种富马酸替诺福韦艾拉酚胺的制备方法
CN108586532B (zh) * 2018-04-03 2020-05-08 科兴生物制药股份有限公司 一种富马酸替诺福韦二吡呋酯的制备方法
CN108409789A (zh) * 2018-04-03 2018-08-17 山东科兴生物制品有限公司 一种替诺福韦二吡呋酯的制备方法
CN108299500A (zh) * 2018-04-04 2018-07-20 安徽安科恒益药业有限公司 一种富马酸替诺福韦艾拉酚胺原料药及其生产工艺
CN108822149B (zh) * 2018-06-01 2020-08-11 成都苑东生物制药股份有限公司 一种富马酸替诺福韦艾拉酚胺关键中间体的制备方法
CN111484527A (zh) * 2019-01-25 2020-08-04 上海清松制药有限公司 一种替诺福韦艾拉酚胺中间体的制备方法
CN110272455A (zh) * 2019-04-15 2019-09-24 浙江车头制药股份有限公司 一种半富马酸替诺福韦艾拉酚胺关键中间体的制备方法
CN110256494A (zh) * 2019-05-10 2019-09-20 成都倍特药业有限公司 替诺福韦艾拉酚胺系列杂质及其合成方法
CN114163471A (zh) * 2020-09-11 2022-03-11 南京华狮新材料有限公司 一种长链高丝氨酸衍生物的制备方法
CN115873258B (zh) * 2023-02-24 2023-05-26 开贝科技(苏州)有限公司 一种改性聚磷酸酯及其制备方法和应用

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CN103665043B (zh) * 2012-08-30 2017-11-10 江苏豪森药业集团有限公司 一种替诺福韦前药及其在医药上的应用
CN105518011B (zh) * 2014-04-21 2018-07-27 四川海思科制药有限公司 氨基磷酸酯类衍生物制备方法及其中间体和中间体的制备方法

Also Published As

Publication number Publication date
CN105531281A (zh) 2016-04-27
WO2015161785A1 (zh) 2015-10-29
WO2015161781A1 (zh) 2015-10-29
CN105518011A (zh) 2016-04-20
CN105518011B (zh) 2018-07-27
CN105531281B (zh) 2017-12-15

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Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20230424