HK1215436A1 - 取代的 -甲基氨基甲酰基- -氟苯基氨基 四氫呋喃- -甲酸 變體 和其酯,其製備方法和用途 - Google Patents

取代的 -甲基氨基甲酰基- -氟苯基氨基 四氫呋喃- -甲酸 變體 和其酯,其製備方法和用途

Info

Publication number
HK1215436A1
HK1215436A1 HK16103440.2A HK16103440A HK1215436A1 HK 1215436 A1 HK1215436 A1 HK 1215436A1 HK 16103440 A HK16103440 A HK 16103440A HK 1215436 A1 HK1215436 A1 HK 1215436A1
Authority
HK
Hong Kong
Prior art keywords
fluorophenylam
methylcarbamoyl
variants
ester
substituted
Prior art date
Application number
HK16103440.2A
Other languages
English (en)
Inventor
亞歷山大‧瓦西裡耶維奇‧伊瓦切恩科
‧米季金
‧克拉夫琴科
‧沃羅比約夫
‧特裡菲倫科夫
Original Assignee
Ltd Liability Company Avionco (Avionco Llc)
Andrey Alexandrovich Ivashchenko
Nikolay Filippovich Savchuk
Alexandre Vasilievich Ivachtchenko
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ltd Liability Company Avionco (Avionco Llc), Andrey Alexandrovich Ivashchenko, Nikolay Filippovich Savchuk, Alexandre Vasilievich Ivachtchenko filed Critical Ltd Liability Company Avionco (Avionco Llc)
Publication of HK1215436A1 publication Critical patent/HK1215436A1/zh

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/04Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D307/18Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/24Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D491/00Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/10Spiro-condensed systems
    • C07D491/107Spiro-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00Compounds containing elements of Groups 4 or 14 of the Periodic System
    • C07F7/02Silicon compounds
    • C07F7/08Compounds having one or more C—Si linkages
    • C07F7/0803Compounds with Si-C or Si-Si linkages
    • C07F7/081Compounds with Si-C or Si-Si linkages comprising at least one atom selected from the elements N, O, halogen, S, Se or Te
    • C07F7/0812Compounds with Si-C or Si-Si linkages comprising at least one atom selected from the elements N, O, halogen, S, Se or Te comprising a heterocyclic ring
HK16103440.2A 2013-02-27 2016-03-23 取代的 -甲基氨基甲酰基- -氟苯基氨基 四氫呋喃- -甲酸 變體 和其酯,其製備方法和用途 HK1215436A1 (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
RU2013108672/04A RU2520134C1 (ru) 2013-02-27 2013-02-27 Замещенные (r)-3-(4-метилкарбамоил-3-фторфениламино)-тетрагидро-фуран-3-енкарбоновые кислоты и их эфиры, способ их получения и применения
PCT/RU2014/000122 WO2014133416A2 (ru) 2013-02-27 2014-02-26 Замещенная (r)-3-(4-метилкарбамоил-3-фторфениламино)тетрагидрофуран-3-енкарбоновая кислота (варианты) и ее эфир, способ получения и применения

Publications (1)

Publication Number Publication Date
HK1215436A1 true HK1215436A1 (zh) 2016-08-26

Family

ID=51216931

Family Applications (1)

Application Number Title Priority Date Filing Date
HK16103440.2A HK1215436A1 (zh) 2013-02-27 2016-03-23 取代的 -甲基氨基甲酰基- -氟苯基氨基 四氫呋喃- -甲酸 變體 和其酯,其製備方法和用途

Country Status (11)

Country Link
US (1) US20160016925A1 (zh)
EP (1) EP2963026B1 (zh)
JP (1) JP6341939B2 (zh)
KR (1) KR102204267B1 (zh)
CN (2) CN105008340A (zh)
AU (1) AU2014221468B2 (zh)
CA (1) CA2901107C (zh)
EA (1) EA027369B1 (zh)
HK (1) HK1215436A1 (zh)
RU (1) RU2520134C1 (zh)
WO (1) WO2014133416A2 (zh)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2557235C1 (ru) * 2014-07-08 2015-07-20 Александр Васильевич Иващенко Замещенные 2-тиоксо-имидазолидин-4-оны и их спироаналоги, противораковый активный компонент, фармацевтическая композиция, лекарственный препарат, способ лечения рака простаты

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101431407B1 (ko) * 2005-05-13 2014-08-18 더 리전트 오브 더 유니버시티 오브 캘리포니아 디아릴히단토인 화합물
AU2007245022A1 (en) * 2006-03-29 2007-11-08 The Regents Of The University Of California Diarylthiohydantoin compounds
PE20081834A1 (es) * 2006-12-31 2009-01-16 Boehringer Ingelheim Int Proceso para la sintesis de derivados de acido 3-amino-tetrahidrofuran-3-carboxilico y uso de los mismos como medicamentos
WO2008119015A2 (en) * 2007-03-27 2008-10-02 Sloan-Kettering Institute For Cancer Research Synthesis of thiohydantoins
EP2416657A4 (en) * 2009-04-09 2012-09-05 Medivation Prostate Therapeutics Inc COMPOUNDS COMPRISING SUBSTITUTED DI-ARYLHYDANTOIDS AND DI-ARYLTHIOHYDANTOINES AND METHODS OF USE THEREOF
ES2671343T3 (es) 2010-02-24 2018-06-06 Medivation Prostate Therapeutics Llc Procesos para la síntesis de compuestos de diariltiohidantoína y diarilhidantoína
RU2434851C1 (ru) * 2010-07-22 2011-11-27 Александр Васильевич Иващенко Циклические n, n'-диарилтиомочевины или n, n'-диарилмочевины - антагонисты андрогенных рецепторов, противораковое средство, способ получения и применения

Also Published As

Publication number Publication date
CN105008340A (zh) 2015-10-28
WO2014133416A3 (ru) 2014-12-18
JP2016510025A (ja) 2016-04-04
CA2901107A1 (en) 2014-09-04
EP2963026A4 (en) 2016-08-03
KR20150130327A (ko) 2015-11-23
EP2963026B1 (en) 2020-04-29
WO2014133416A2 (ru) 2014-09-04
RU2520134C1 (ru) 2014-06-20
WO2014133416A8 (ru) 2015-09-11
KR102204267B1 (ko) 2021-01-18
EA201500754A1 (ru) 2016-01-29
CN110669027A (zh) 2020-01-10
US20160016925A1 (en) 2016-01-21
EP2963026A2 (en) 2016-01-06
JP6341939B2 (ja) 2018-06-13
CA2901107C (en) 2020-10-27
AU2014221468A1 (en) 2015-09-24
EA027369B1 (ru) 2017-07-31
AU2014221468B2 (en) 2018-05-17
CN110669027B (zh) 2021-07-06

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