HK1214558A1 - Circuit based optoelectronic tweezers - Google Patents

Circuit based optoelectronic tweezers

Info

Publication number
HK1214558A1
HK1214558A1 HK16102624.2A HK16102624A HK1214558A1 HK 1214558 A1 HK1214558 A1 HK 1214558A1 HK 16102624 A HK16102624 A HK 16102624A HK 1214558 A1 HK1214558 A1 HK 1214558A1
Authority
HK
Hong Kong
Prior art keywords
circuit based
based optoelectronic
optoelectronic tweezers
tweezers
circuit
Prior art date
Application number
HK16102624.2A
Other languages
Chinese (zh)
Inventor
W Short Steven
C Wu Ming
Original Assignee
Berkeley Lights Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Berkeley Lights Inc filed Critical Berkeley Lights Inc
Publication of HK1214558A1 publication Critical patent/HK1214558A1/en

Links

Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B03SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03CMAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C5/00Separating dispersed particles from liquids by electrostatic effect
    • B03C5/005Dielectrophoresis, i.e. dielectric particles migrating towards the region of highest field strength
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502761Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip specially adapted for handling suspended solids or molecules independently from the bulk fluid flow, e.g. for trapping or sorting beads, for physically stretching molecules
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B03SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03CMAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C5/00Separating dispersed particles from liquids by electrostatic effect
    • B03C5/02Separators
    • B03C5/022Non-uniform field separators
    • B03C5/026Non-uniform field separators using open-gradient differential dielectric separation, i.e. using electrodes of special shapes for non-uniform field creation, e.g. Fluid Integrated Circuit [FIC]
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00Moving or stopping fluids
    • B01L2400/04Moving fluids with specific forces or mechanical means
    • B01L2400/0403Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0415Moving fluids with specific forces or mechanical means specific forces electrical forces, e.g. electrokinetic
    • B01L2400/0424Dielectrophoretic forces
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B03SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03CMAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C2201/00Details of magnetic or electrostatic separation
    • B03C2201/26Details of magnetic or electrostatic separation for use in medical applications

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Microelectronics & Electronic Packaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Electrochemistry (AREA)
  • Molecular Biology (AREA)
  • Fluid Mechanics (AREA)
  • Physics & Mathematics (AREA)
  • Dispersion Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Hematology (AREA)
  • Clinical Laboratory Science (AREA)
  • Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
  • Mechanical Light Control Or Optical Switches (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Electronic Switches (AREA)
  • Light Receiving Elements (AREA)
  • Solid State Image Pick-Up Elements (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
HK16102624.2A 2012-11-08 2016-03-08 Circuit based optoelectronic tweezers HK1214558A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261724168P 2012-11-08 2012-11-08
US14/051,004 US9403172B2 (en) 2012-11-08 2013-10-10 Circuit based optoelectronic tweezers
PCT/US2013/067564 WO2014074367A1 (en) 2012-11-08 2013-10-30 Circuit based optoelectronic tweezers

Publications (1)

Publication Number Publication Date
HK1214558A1 true HK1214558A1 (en) 2016-07-29

Family

ID=50621363

Family Applications (3)

Application Number Title Priority Date Filing Date
HK18104724.5A HK1245185A1 (en) 2012-11-08 2016-02-03 Circuit based optoelectronic tweezers
HK16101269.4A HK1213218A1 (en) 2012-11-08 2016-02-03 Circuit based optoelectronic tweezers
HK16102624.2A HK1214558A1 (en) 2012-11-08 2016-03-08 Circuit based optoelectronic tweezers

Family Applications Before (2)

Application Number Title Priority Date Filing Date
HK18104724.5A HK1245185A1 (en) 2012-11-08 2016-02-03 Circuit based optoelectronic tweezers
HK16101269.4A HK1213218A1 (en) 2012-11-08 2016-02-03 Circuit based optoelectronic tweezers

Country Status (11)

Country Link
US (2) US9403172B2 (en)
EP (1) EP2916954B1 (en)
JP (1) JP6293160B2 (en)
KR (1) KR102141261B1 (en)
CN (2) CN104955574B (en)
CA (2) CA3101130C (en)
DK (1) DK2916954T3 (en)
HK (3) HK1245185A1 (en)
IL (1) IL238451B (en)
SG (1) SG11201600581SA (en)
WO (1) WO2014074367A1 (en)

Families Citing this family (54)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102113377B1 (en) 2013-10-22 2020-05-21 버클리 라잇츠, 인크. Microfluidic devices having isolation pens and methods of testing biological micro-objects with same
EP3060912B1 (en) 2013-10-22 2020-07-15 Berkeley Lights, Inc. Method and microfluidic device for assaying biological activity
US9889445B2 (en) 2013-10-22 2018-02-13 Berkeley Lights, Inc. Micro-fluidic devices for assaying biological activity
US20150166326A1 (en) 2013-12-18 2015-06-18 Berkeley Lights, Inc. Capturing Specific Nucleic Acid Materials From Individual Biological Cells In A Micro-Fluidic Device
US11192107B2 (en) 2014-04-25 2021-12-07 Berkeley Lights, Inc. DEP force control and electrowetting control in different sections of the same microfluidic apparatus
US20150306599A1 (en) 2014-04-25 2015-10-29 Berkeley Lights, Inc. Providing DEP Manipulation Devices And Controllable Electrowetting Devices In The Same Microfluidic Apparatus
US20150346148A1 (en) * 2014-05-28 2015-12-03 Agilent Technologies, Inc. Method and Apparatus for Manipulating Samples Using Optoelectronic Forces
KR102425337B1 (en) * 2014-08-15 2022-07-25 더 리전트 오브 더 유니버시티 오브 캘리포니아 Self-locking optoelectronic tweezer and its fabrication
AU2015360849B2 (en) 2014-12-08 2018-10-11 Berkeley Lights, Inc. Microfluidic device comprising lateral/vertical transistor structures and process of making and using same
CN107249742B (en) 2014-12-08 2019-12-06 伯克利之光生命科技公司 Directional flow actuated microfluidic structures in microfluidic devices and methods of using the same
EP3919892A1 (en) 2014-12-09 2021-12-08 Berkeley Lights, Inc. Automated detection and repositioning of micro-objects in microfluidic devices
JP2018508743A (en) 2014-12-10 2018-03-29 バークレー ライツ,インコーポレイテッド System for operating an electrokinetic device
WO2016094715A2 (en) 2014-12-10 2016-06-16 Berkeley Lights, Inc. Movement and selection of micro-objects in a microfluidic apparatus
EP3286298A1 (en) 2015-04-22 2018-02-28 Berkeley Lights, Inc. Culturing station for microfluidic device
IL284235B (en) 2015-04-22 2022-07-01 Berkeley Lights Inc Kits and methods for preparing microfluidic devices for cell culture
US10101250B2 (en) 2015-04-22 2018-10-16 Berkeley Lights, Inc. Manipulation of cell nuclei in a micro-fluidic device
CN107810059B (en) 2015-04-22 2021-03-23 伯克利之光生命科技公司 Freezing and archiving cells on a microfluidic device
EP3096134B1 (en) * 2015-05-21 2019-07-24 Nokia Technologies Oy An apparatus and method for providing a time varying voltage
TWI781484B (en) 2015-10-27 2022-10-21 美商伯克利之光生命科技公司 Microfluidic apparatus having an optimized electrowetting surface and related systems and methods
US10799865B2 (en) 2015-10-27 2020-10-13 Berkeley Lights, Inc. Microfluidic apparatus having an optimized electrowetting surface and related systems and methods
CN108495712A (en) 2015-11-23 2018-09-04 伯克利之光生命科技公司 Generated in-situ microfluid isolation structure, kit and its application method
KR102466814B1 (en) 2015-12-08 2022-11-11 버클리 라잇츠, 인크. Microfluidic devices and kits and methods for their use
CN108698814A (en) 2015-12-30 2018-10-23 伯克利之光生命科技公司 Microfluidic device, kit and its method of convection current and displacement for optical drive
WO2017117521A1 (en) 2015-12-31 2017-07-06 Berkeley Lights, Inc. Tumor infilitrating cells engineered to express a pro-inflammatory polypeptide
TWI756199B (en) 2016-01-15 2022-03-01 美商伯克利之光生命科技公司 Methods of producing patient-specific anti-cancer therapeutics and methods of treatment therefor
WO2017160991A1 (en) 2016-03-16 2017-09-21 Lavieu Gregory G Methods, systems and devices for selection and generation of genome edited clones
SG11201808022WA (en) 2016-03-17 2018-10-30 Berkeley Lights Inc Selection and cloning of t lymphocytes in a microfluidic device
DK3436469T3 (en) 2016-03-31 2022-03-21 Berkeley Lights Inc NUCLEIC ACID STABILIZATION REAGENTS, KITS AND METHODS OF USING IT
US10675625B2 (en) 2016-04-15 2020-06-09 Berkeley Lights, Inc Light sequencing and patterns for dielectrophoretic transport
KR102421818B1 (en) 2016-04-15 2022-07-15 버클리 라잇츠, 인크. Methods, systems and kits for in-pen assays
SG11201809539RA (en) 2016-05-26 2018-12-28 Berkeley Lights Inc Covalently modified surfaces, kits, and methods of preparation and use
JP7038100B2 (en) 2016-07-21 2022-03-17 バークレー ライツ,インコーポレイテッド Sorting of T lymphocytes with a microfluidic device
CA3038535A1 (en) 2016-10-01 2018-04-05 Berkeley Lights, Inc. Dna barcode compositions and methods of in situ identification in a microfluidic device
EP3529611B1 (en) 2016-10-23 2022-11-23 Berkeley Lights, Inc. Methods for screening b cell lymphocytes
CN116894976A (en) 2016-12-01 2023-10-17 伯克利之光生命科技公司 Automated detection and repositioning of micro-objects in a microfluidic device
KR102551430B1 (en) 2016-12-01 2023-07-05 버클리 라잇츠, 인크. Apparatuses, systems and methods for imaging micro-objects
CA3046827A1 (en) 2016-12-12 2018-06-21 xCella Biosciences, Inc. Methods and systems for screening using microcapillary arrays
WO2018126205A1 (en) 2016-12-30 2018-07-05 The Regents Of The University Of California Methods for selection and generation of genome edited t cells
WO2018226900A2 (en) 2017-06-06 2018-12-13 Zymergen Inc. A htp genomic engineering platform for improving fungal strains
SG11202000425QA (en) 2017-07-21 2020-02-27 Berkeley Lights Inc Antigen-presenting synthetic surfaces, covalently functionalized surfaces, activated t cells, and uses thereof
WO2019075476A2 (en) 2017-10-15 2019-04-18 Berkeley Lights, Inc. Methods, systems and kits for in-pen assays
CN112204380A (en) 2018-05-31 2021-01-08 伯克利之光生命科技公司 Automatic detection and characterization of micro-objects in microfluidic devices
WO2019236848A1 (en) 2018-06-06 2019-12-12 Zymergen Inc. Manipulation of genes involved in signal transduction to control fungal morphology during fermentation and production
KR20210063362A (en) 2018-09-21 2021-06-01 버클리 라잇츠, 인크. Functionalized Well Plates, Methods of Making and Using the Same
WO2020106646A1 (en) 2018-11-19 2020-05-28 Berkeley Lights, Inc. Microfluidic device with programmable switching elements
CN109622085B (en) 2019-01-31 2021-12-24 京东方科技集团股份有限公司 Driving method and device of micro-fluidic chip and micro-fluidic system
WO2020168258A1 (en) * 2019-02-15 2020-08-20 Berkeley Lights, Inc. Laser-assisted repositioning of a micro-object and culturing of an attachment-dependent cell in a microfluidic environment
EP3962652A4 (en) 2019-04-30 2023-01-18 Berkeley Lights, Inc. Methods for encapsulating and assaying cells
CN114829626A (en) 2019-10-10 2022-07-29 1859公司 Methods and systems for microfluidic screening
KR20220113683A (en) 2019-11-17 2022-08-16 버클리 라잇츠, 인크. Systems and methods for analysis of biological samples
US11479779B2 (en) 2020-07-31 2022-10-25 Zymergen Inc. Systems and methods for high-throughput automated strain generation for non-sporulating fungi
GB202109967D0 (en) * 2021-07-09 2021-08-25 Lightcast Discovery Ltd Improvements in or relating to imaging microdroplets in a microfluidic device
US20240050948A1 (en) * 2022-08-10 2024-02-15 Cytoaurora Biotechnologies, Inc. Contactless selection device, light sensing structure thereof, and biological particle selection apparatus
JP2024049813A (en) 2022-09-29 2024-04-10 横河電機株式会社 Dielectrophoresis Apparatus

Family Cites Families (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE366418T1 (en) 1996-04-25 2007-07-15 Bioarray Solutions Ltd LIGHT-REGULATED, ELECTROKINETIC COMPOSITION OF PARTICLES ON SURFACES
US6294063B1 (en) 1999-02-12 2001-09-25 Board Of Regents, The University Of Texas System Method and apparatus for programmable fluidic processing
US6942776B2 (en) 1999-05-18 2005-09-13 Silicon Biosystems S.R.L. Method and apparatus for the manipulation of particles by means of dielectrophoresis
AU2427301A (en) * 1999-12-01 2001-06-12 Regents Of The University Of California, The Electric-field-assisted fluidic assembly of inorganic and organic materials, molecules and like small things including living cells
GB2389260B (en) * 2002-05-31 2006-03-29 Leo Electron Microscopy Ltd Transresistance amplifier for a charged particle detector
US6958132B2 (en) 2002-05-31 2005-10-25 The Regents Of The University Of California Systems and methods for optical actuation of microfluidics based on opto-electrowetting
JP4039201B2 (en) * 2002-08-20 2008-01-30 ソニー株式会社 Hybridization detection unit, sensor chip, and hybridization method
JP4328168B2 (en) * 2003-10-02 2009-09-09 ソニー株式会社 Detection unit for interaction between substances using capillary phenomenon, method using the detection unit, and substrate for bioassay
EP1735428A4 (en) * 2004-04-12 2010-11-10 Univ California Optoelectronic tweezers for microparticle and cell manipulation
JP3952042B2 (en) * 2004-06-07 2007-08-01 ソニー株式会社 Hybridization detection unit including an electrode having a concave portion and a DNA chip including the detection unit
US7088116B1 (en) 2005-02-09 2006-08-08 Haian Lin Optoelectronic probe
ITBO20050646A1 (en) * 2005-10-26 2007-04-27 Silicon Biosystem S R L METHOD AND APPARATUS FOR CHARACTERIZATION AND COUNTING OF PARTICLES
EP1951742A4 (en) 2005-10-27 2011-06-01 Life Technologies Corp Optoelectronic separation of biomolecules
WO2008072166A1 (en) * 2006-12-12 2008-06-19 Koninklijke Philips Electronics N.V. Method and apparatus for cell analysis
WO2008119066A1 (en) * 2007-03-28 2008-10-02 The Regents Of The University Of California Single-sided lateral-field and phototransistor-based optoelectronic tweezers
CN101135680B (en) * 2007-07-13 2011-04-20 东南大学 Light-induction dielectrophoresis auxiliary unicellular dielectric spectrum automatic test equipment and testing method
WO2009032087A1 (en) * 2007-08-29 2009-03-12 Canon U.S. Life Sciences, Inc. Microfluidic devices with integrated resistive heater electrodes
JP2009158570A (en) * 2007-12-25 2009-07-16 Seiko Instruments Inc Photodetection semiconductor device, photodetector, and image display device
FR2933315B1 (en) * 2008-07-07 2012-02-10 Commissariat Energie Atomique MICROFLUIDIC DEVICE FOR DISPLACING LIQUID
KR100991752B1 (en) 2008-07-15 2010-11-03 한국과학기술원 Apparatus and Method for Microparticle Manipulation Using Single Planar Optoelectronic Device
CN101344518B (en) * 2008-08-15 2012-04-11 东南大学 Multi-mode set integration dielectric characterization apparatus and method of micro-nano biological particle
WO2010115167A2 (en) 2009-04-03 2010-10-07 The Regents Of The University Of California Methods and devices for sorting cells and other biological particulates
JP5184634B2 (en) * 2009-11-19 2013-04-17 パナソニック株式会社 Display panel device, display device and control method thereof
US9533306B2 (en) 2010-08-02 2017-01-03 The Regents Of The University Of California Single sided continuous optoelectrowetting (SCEOW) device for droplet manipulation with light patterns
US9227200B2 (en) 2011-06-03 2016-01-05 The Regents Of The University Of California Microfluidic devices with flexible optically transparent electrodes
US8980075B2 (en) * 2011-07-29 2015-03-17 The Texas A & M University System Digital microfluidic platform for actuating and heating individual liquid droplets
CN102764676B (en) * 2012-07-23 2014-08-06 西安交通大学 Microfluidic chip with non-contact light drive-bipolar electrode (BPE)
US20150166326A1 (en) * 2013-12-18 2015-06-18 Berkeley Lights, Inc. Capturing Specific Nucleic Acid Materials From Individual Biological Cells In A Micro-Fluidic Device

Also Published As

Publication number Publication date
CN107252733A (en) 2017-10-17
CA2890352C (en) 2021-01-26
EP2916954A4 (en) 2016-06-29
EP2916954A1 (en) 2015-09-16
CN104955574A (en) 2015-09-30
US20140124370A1 (en) 2014-05-08
HK1245185A1 (en) 2018-08-24
DK2916954T3 (en) 2019-04-08
CN107252733B (en) 2020-12-01
EP2916954B1 (en) 2019-01-02
JP6293160B2 (en) 2018-03-14
IL238451A0 (en) 2015-06-30
HK1213218A1 (en) 2016-06-30
US9403172B2 (en) 2016-08-02
WO2014074367A1 (en) 2014-05-15
JP2016505349A (en) 2016-02-25
US9895699B2 (en) 2018-02-20
CA2890352A1 (en) 2014-05-15
SG11201600581SA (en) 2016-03-30
CA3101130A1 (en) 2014-05-15
CN104955574B (en) 2017-05-17
CA3101130C (en) 2023-03-14
US20160318038A1 (en) 2016-11-03
IL238451B (en) 2018-04-30
KR102141261B1 (en) 2020-08-05
KR20150083890A (en) 2015-07-20

Similar Documents

Publication Publication Date Title
HK1214558A1 (en) Circuit based optoelectronic tweezers
ZA201604518B (en) Optoelectronic device
GB2562626B (en) Integrated circuit structure
PT3336866T (en) Optoelectronic device
SG10201508450UA (en) Opto-electronic module
EP2881787A4 (en) Light receiving circuit
EP2845220A4 (en) Techniques for forming optoelectronic devices
SG11201404918YA (en) Etching composition
EP2699065A4 (en) Circuit substrate
GB201220965D0 (en) Light-projecting devices
EP2802914A4 (en) Optical connections
ZA201302862B (en) Light adjusting circuit
HK1176106A1 (en) Lens
GB201216605D0 (en) Optoelectronic device
EP2908158A4 (en) Optical circuit
EP2923383A4 (en) Photodetection
TWM476276U (en) Lens structure
EP2810109C0 (en) Planar optical branching circuit
HK1208918A1 (en) Thermocompensated timepiece circuit
AP00445S1 (en) Substrate
GB201211785D0 (en) Lens
GB2498528B (en) Multifunctional light
GB201214413D0 (en) Festivalstand (festistand)
GB201216763D0 (en) Blokprintz (wallblocks)
GB201203779D0 (en) (LASERComfortSET)