HK1206987A1 - 放射線損害的預防和/或治療劑 - Google Patents

放射線損害的預防和/或治療劑

Info

Publication number
HK1206987A1
HK1206987A1 HK15107650.9A HK15107650A HK1206987A1 HK 1206987 A1 HK1206987 A1 HK 1206987A1 HK 15107650 A HK15107650 A HK 15107650A HK 1206987 A1 HK1206987 A1 HK 1206987A1
Authority
HK
Hong Kong
Prior art keywords
prophylactic
therapeutic agent
radiation damage
radiation
damage
Prior art date
Application number
HK15107650.9A
Other languages
English (en)
Inventor
田中徹
中島元夫
安部史紀
伊東秀典
高橋究
松島綱治
上羽悟史
阿部淳
Original Assignee
Univ Tokyo
Sbi Pharmaceuticals Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Tokyo, Sbi Pharmaceuticals Co Ltd filed Critical Univ Tokyo
Publication of HK1206987A1 publication Critical patent/HK1206987A1/zh

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/235—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group
    • A61K31/24—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group having an amino or nitro group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/555—Heterocyclic compounds containing heavy metals, e.g. hemin, hematin, melarsoprol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A61K33/26—Iron; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Emergency Medicine (AREA)
  • Inorganic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Toxicology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
HK15107650.9A 2012-07-23 2015-08-08 放射線損害的預防和/或治療劑 HK1206987A1 (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2012163110 2012-07-23
PCT/JP2013/004292 WO2014017046A1 (ja) 2012-07-23 2013-07-11 放射線障害の予防及び／又は治療剤

Publications (1)

Publication Number Publication Date
HK1206987A1 true HK1206987A1 (zh) 2016-01-22

Family

ID=49996874

Family Applications (2)

Application Number Title Priority Date Filing Date
HK15106310.3A HK1205687A1 (zh) 2012-07-23 2015-07-02 輻射損害的預防和/或治療劑
HK15107650.9A HK1206987A1 (zh) 2012-07-23 2015-08-08 放射線損害的預防和/或治療劑

Family Applications Before (1)

Application Number Title Priority Date Filing Date
HK15106310.3A HK1205687A1 (zh) 2012-07-23 2015-07-02 輻射損害的預防和/或治療劑

Country Status (7)

Country Link
US (1) US9895331B2 (zh)
EP (1) EP2875812B1 (zh)
JP (1) JP5920902B2 (zh)
CN (1) CN104487066B (zh)
HK (2) HK1205687A1 (zh)
TW (1) TWI637743B (zh)
WO (1) WO2014017046A1 (zh)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2004245567B2 (en) 2003-06-03 2011-06-23 Oxford University Innovation Limited Nutritional supplements and therapeutic compositions comprising (R)-3-hydroxybutyrate derivatives
US8642654B2 (en) 2009-04-16 2014-02-04 Isis Innovation Limited Hydroxybutyrate ester and medical use thereof
CA2922223C (en) * 2012-11-05 2021-11-09 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services And Human Services Ketone bodies to protect tissues from damage by ionizing radiation
GB201304467D0 (en) 2013-03-12 2013-04-24 Tdeltas Ltd Compound for use in protecting skin
GB2515603B (en) 2013-03-14 2015-10-14 Isis Innovation Process for producing (R)-3-Hydroxybutyl (R)-3-Hydroxybutyrate
JP6923164B2 (ja) 2016-12-27 2021-08-18 ＭｉＺ株式会社 放射線障害防御剤
CN111060697A (zh) * 2019-02-24 2020-04-24 中国疾病预防控制中心辐射防护与核安全医学所 一种利用hmgb1的小肠放射性损伤标记方法

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5079262A (en) * 1989-07-28 1992-01-07 Queen's University At Kingston Method of detection and treatment of malignant and non-malignant lesions utilizing 5-aminolevulinic acid
JPH0539218A (ja) 1991-08-05 1993-02-19 Sanwa Kagaku Kenkyusho Co Ltd 放射線障害治療剤
JP3170364B2 (ja) 1992-11-05 2001-05-28 中外製薬株式会社 放射線障害防護剤
JPH07165602A (ja) 1993-12-16 1995-06-27 Kirin Brewery Co Ltd 放射線障害防護剤
AT407833B (de) 1995-06-01 2001-06-25 Nowicky Wassyl Dr Mittel zur behandlung von strahlenschäden
JP2003335674A (ja) 2002-03-12 2003-11-25 Mitsubishi Pharma Corp 放射線障害の予防剤および治療剤
JP2004043391A (ja) 2002-07-15 2004-02-12 Eisai Co Ltd 放射線障害軽減剤
EP1694322A2 (en) 2003-11-26 2006-08-30 Arqule, Inc. Use of beta-lapachone for protecting against radiation injury
WO2006033412A1 (ja) 2004-09-24 2006-03-30 Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo 放射線障害軽減剤
JP2007302640A (ja) 2006-05-15 2007-11-22 Natl Inst Of Radiological Sciences 抗放射線被ばく障害剤
EP2305237B1 (en) 2008-05-14 2014-04-30 SBI Pharmaceuticals Co., Ltd. Therapeutic agent for male sterility
JP5295652B2 (ja) 2008-06-16 2013-09-18 Ｓｂｉファーマ株式会社 光障害の軽減剤
EP2340821B1 (en) 2008-10-27 2017-01-25 SBI Pharmaceuticals Co., Ltd. Prophylactic/ameliorating agent for adult diseases comprising 5-aminolevulinic acid, derivative of 5-aminolevulinic acid, or salt of 5-aminolevulinic acid or the derivative of 5-aminolevulinic acid as active ingredient
JP5611548B2 (ja) * 2009-07-08 2014-10-22 Ｓｂｉファーマ株式会社 ５−アミノレブリン酸若しくはその誘導体、又はそれらの塩を有効成分とするがんの予防・改善剤
JP5553306B2 (ja) 2010-03-30 2014-07-16 国立大学法人福井大学 放射線障害防護剤
US9469598B2 (en) * 2011-10-12 2016-10-18 Sbi Pharmaceuticals Co., Ltd. Erythropoietin production-promoting agent

Also Published As

Publication number Publication date
HK1205687A1 (zh) 2015-12-24
JPWO2014017046A1 (ja) 2016-07-07
TWI637743B (zh) 2018-10-11
CN104487066B (zh) 2020-06-09
WO2014017046A1 (ja) 2014-01-30
TW201412307A (zh) 2014-04-01
JP5920902B2 (ja) 2016-05-18
EP2875812A4 (en) 2016-02-24
US20150190356A1 (en) 2015-07-09
CN104487066A (zh) 2015-04-01
EP2875812B1 (en) 2019-09-04
EP2875812A1 (en) 2015-05-27
US9895331B2 (en) 2018-02-20

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