HK1194977A1 - 奈妥比坦與帕洛諾司瓊的具療效的組合 - Google Patents
奈妥比坦與帕洛諾司瓊的具療效的組合Info
- Publication number
- HK1194977A1 HK1194977A1 HK14108329.9A HK14108329A HK1194977A1 HK 1194977 A1 HK1194977 A1 HK 1194977A1 HK 14108329 A HK14108329 A HK 14108329A HK 1194977 A1 HK1194977 A1 HK 1194977A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- netupitant
- palonosetron
- therapeutic combinations
- therapeutic
- combinations
- Prior art date
Links
- QBADKJRRVGKRHP-JLXQGRKUSA-N (3as)-2-[(3s)-1-azabicyclo[2.2.2]octan-3-yl]-3a,4,5,6-tetrahydro-3h-benzo[de]isoquinolin-1-one;2-[3,5-bis(trifluoromethyl)phenyl]-n,2-dimethyl-n-[6-(4-methylpiperazin-1-yl)-4-[(3z)-penta-1,3-dien-3-yl]pyridin-3-yl]propanamide Chemical compound C1N(CC2)CCC2[C@@H]1N1C(=O)C(C=CC=C2CCC3)=C2[C@H]3C1.C\C=C(\C=C)C1=CC(N2CCN(C)CC2)=NC=C1N(C)C(=O)C(C)(C)C1=CC(C(F)(F)F)=CC(C(F)(F)F)=C1 QBADKJRRVGKRHP-JLXQGRKUSA-N 0.000 title 1
- 230000001225 therapeutic effect Effects 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/473—Quinolines; Isoquinolines ortho- or peri-condensed with carbocyclic ring systems, e.g. acridines, phenanthridines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4748—Quinolines; Isoquinolines forming part of bridged ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4808—Preparations in capsules, e.g. of gelatin, of chocolate characterised by the form of the capsule or the structure of the filling; Capsules containing small tablets; Capsules with outer layer for immediate drug release
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4816—Wall or shell material
- A61K9/4825—Proteins, e.g. gelatin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4858—Organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4866—Organic macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/10—Laxatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/12—Antidiarrhoeals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A61P31/22—Antivirals for DNA viruses for herpes viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201161548514P | 2011-10-18 | 2011-10-18 | |
PCT/IB2012/002013 WO2013057554A2 (en) | 2011-10-18 | 2012-10-10 | Therapeutic combinations of netupitant and palonosetron |
Publications (1)
Publication Number | Publication Date |
---|---|
HK1194977A1 true HK1194977A1 (zh) | 2014-10-31 |
Family
ID=47178220
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK14110976.1A HK1198121A1 (zh) | 2011-10-18 | 2014-08-14 | 奈妥比坦與帕洛諾司瓊的具療效的組合 |
HK14108329.9A HK1194977A1 (zh) | 2011-10-18 | 2014-08-14 | 奈妥比坦與帕洛諾司瓊的具療效的組合 |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK14110976.1A HK1198121A1 (zh) | 2011-10-18 | 2014-08-14 | 奈妥比坦與帕洛諾司瓊的具療效的組合 |
Country Status (11)
Country | Link |
---|---|
US (1) | US9358228B2 (zh) |
EP (2) | EP2744497B1 (zh) |
JP (1) | JP2014530249A (zh) |
CN (3) | CN105412110B (zh) |
DK (1) | DK2744497T3 (zh) |
ES (1) | ES2579616T3 (zh) |
HK (2) | HK1198121A1 (zh) |
HU (1) | HUE030811T2 (zh) |
PL (1) | PL2744497T3 (zh) |
PT (1) | PT2744497T (zh) |
WO (1) | WO2013057554A2 (zh) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN108721214B (zh) * | 2017-04-14 | 2020-06-16 | 和龙 | 奈妥吡坦和帕洛诺司琼复方纳米粒溶液、纳米粒及制备方法和用途 |
Family Cites Families (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IL96486A (en) | 1989-11-28 | 1995-03-30 | Syntex Inc | Preparation tricyclic compounds and pharmaceutical preparations containing them |
US5510486A (en) | 1994-07-26 | 1996-04-23 | Syntex (U.S.A.) Inc. | Process for preparing 2-(1-azabicyclo 2.2.2!oct-3-yl)-2,3,3A,4,5,6-hexahydro-1H-benz de!isoquinolin-1-one |
GB9721139D0 (en) * | 1997-10-07 | 1997-12-03 | Glaxo Group Ltd | Medicaments |
JP2002537245A (ja) * | 1999-02-18 | 2002-11-05 | ノバルティス アクチエンゲゼルシャフト | 5−ht3レセプターアンタゴニストの使用 |
DK1394150T3 (da) | 1999-02-24 | 2011-03-21 | Hoffmann La Roche | 4-phenylpyridinderivater og deres anvendelse som NK-1-receptorantagonister |
KR100501608B1 (ko) | 2000-07-14 | 2005-07-18 | 에프. 호프만-라 로슈 아게 | 4-페닐-피리딘 유도체의 nk1 수용체의 길항성선구약물로서의 n-산화물 |
ES2272408T3 (es) | 2000-12-14 | 2007-05-01 | F. Hoffmann-La Roche Ag | Matriz lipidica autoemulsificante (selm). |
BRPI0406749A (pt) * | 2003-01-13 | 2005-12-20 | Dynogen Pharmaceuticals Inc | Métodos relacionados ao tratamento de distúrbios fincionais do intestino e composição farmacêutica |
JO2735B1 (en) | 2003-01-30 | 2013-09-15 | هيلسين هيلث كير أس ايه. | Liquid pharmaceutical formations of balloonosterone |
JO2676B1 (en) * | 2004-04-06 | 2012-06-17 | جانسين فارماسوتيكا ان. في | Derivatives of second-aza-spiro- (5,4) -dikan and their use as antihistamines |
EP3269713A1 (en) | 2004-07-01 | 2018-01-17 | OPKO Health, Inc. | Piperidine derivatives as nk1 antagonists |
WO2007128056A1 (en) * | 2006-05-03 | 2007-11-15 | Cnsbio Pty Ltd | Methods and composition for treatment of inflammatory pain |
RS50842B (sr) | 2006-10-24 | 2010-08-31 | Helsinn Healthcare S.A. | Meke kapsule koje sadrže palonosetron hlorovodonik koji ima poboljšanu stabilnost i bioraspoloživost |
US20100316678A1 (en) | 2007-06-28 | 2010-12-16 | Cnsbio Pty Ltd. | Combination methods and compositions for treatment of neuropathic pain |
CN106512010A (zh) * | 2009-11-18 | 2017-03-22 | 赫尔辛医疗股份公司 | 用于治疗中枢介导的恶心及呕吐的组合物及方法 |
-
2012
- 2012-10-10 EP EP12784677.2A patent/EP2744497B1/en active Active
- 2012-10-10 PT PT127846772T patent/PT2744497T/pt unknown
- 2012-10-10 JP JP2014536344A patent/JP2014530249A/ja active Pending
- 2012-10-10 HU HUE12784677A patent/HUE030811T2/hu unknown
- 2012-10-10 CN CN201510670710.XA patent/CN105412110B/zh active Active
- 2012-10-10 PL PL12784677.2T patent/PL2744497T3/pl unknown
- 2012-10-10 CN CN201610834008.7A patent/CN106974912A/zh active Pending
- 2012-10-10 DK DK12784677.2T patent/DK2744497T3/en active
- 2012-10-10 EP EP14165604.1A patent/EP2759298B1/en active Active
- 2012-10-10 ES ES12784677.2T patent/ES2579616T3/es active Active
- 2012-10-10 US US14/351,113 patent/US9358228B2/en active Active
- 2012-10-10 CN CN201280051509.8A patent/CN103889423B/zh active Active
- 2012-10-10 WO PCT/IB2012/002013 patent/WO2013057554A2/en active Application Filing
-
2014
- 2014-08-14 HK HK14110976.1A patent/HK1198121A1/zh unknown
- 2014-08-14 HK HK14108329.9A patent/HK1194977A1/zh not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
WO2013057554A3 (en) | 2013-07-11 |
EP2744497A2 (en) | 2014-06-25 |
EP2759298B1 (en) | 2018-01-17 |
PT2744497T (pt) | 2016-07-18 |
EP2759298A1 (en) | 2014-07-30 |
HK1198121A1 (zh) | 2015-03-13 |
CN105412110A (zh) | 2016-03-23 |
CN106974912A (zh) | 2017-07-25 |
JP2014530249A (ja) | 2014-11-17 |
CN105412110B (zh) | 2018-05-25 |
CN103889423B (zh) | 2016-10-19 |
WO2013057554A2 (en) | 2013-04-25 |
EP2744497B1 (en) | 2016-04-06 |
DK2744497T3 (en) | 2016-08-01 |
HUE030811T2 (hu) | 2017-05-29 |
US20140256737A1 (en) | 2014-09-11 |
ES2579616T3 (es) | 2016-08-12 |
CN103889423A (zh) | 2014-06-25 |
PL2744497T3 (pl) | 2016-10-31 |
US9358228B2 (en) | 2016-06-07 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
IL285985B1 (en) | Therapeutic nuclease preparations and methods | |
EP2804851A4 (en) | THERAPEUTICALLY ACTIVE COMPOUNDS AND METHODS OF USE | |
EP2800743A4 (en) | THERAPEUTIC ACTIVE SUBSTANCES AND METHOD FOR THEIR USE | |
EP2804850A4 (en) | THERAPEUTIC ACTIVE SUBSTANCES AND METHOD FOR THEIR USE | |
EP2884984A4 (en) | THERAPEUTIC COMPOSITIONS AND METHOD | |
HK1201454A1 (zh) | 治療劑及其用途 | |
EP2852397A4 (en) | HUWENTOXIN IV VARIANTS AND METHODS OF USE | |
IL232135A0 (en) | Therapeutic combinations and methods for treating melanoma | |
HK1212225A1 (zh) | 治療性製劑和治療方法 | |
EP2726079A4 (en) | METHOD OF ADMINISTRATION AND TREATMENT | |
EP2750508A4 (en) | COMPOUNDS AND THERAPEUTIC METHODS | |
EP2895186A4 (en) | THERAPEUTIC COMPOSITIONS AND RELATED METHODS | |
EP2710017A4 (en) | MACROCYCLIC THERAPEUTIC AGENTS AND METHODS OF TREATMENT | |
HK1194977A1 (zh) | 奈妥比坦與帕洛諾司瓊的具療效的組合 | |
GB201102213D0 (en) | Inventions and therapy | |
GB201102239D0 (en) | Inventions and therapy | |
GB201102238D0 (en) | Inventions and therapy | |
GB201102236D0 (en) | Inventions and therapy | |
GB201102234D0 (en) | Inventions and therapy | |
GB201102232D0 (en) | Inventions and therapy | |
GB201102231D0 (en) | Inventions and therapy | |
GB201102228D0 (en) | Inventions and therapy | |
GB201102227D0 (en) | Inventions and therapy | |
GB201102226D0 (en) | Inventions and therapy | |
GB201102222D0 (en) | Inventions and therapy |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PC | Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee) |
Effective date: 20201015 |