HK1172931A1 - 可用於檢測 突變的方法、引物、探針和試劑盒 - Google Patents

可用於檢測 突變的方法、引物、探針和試劑盒

Info

Publication number
HK1172931A1
HK1172931A1 HK13100094.0A HK13100094A HK1172931A1 HK 1172931 A1 HK1172931 A1 HK 1172931A1 HK 13100094 A HK13100094 A HK 13100094A HK 1172931 A1 HK1172931 A1 HK 1172931A1
Authority
HK
Hong Kong
Prior art keywords
braf
primers
probes
detection
methods
Prior art date
Application number
HK13100094.0A
Other languages
English (en)
Inventor
Craig Stephens
Kathleen Danenberg
Original Assignee
應答遺傳公司
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 應答遺傳公司 filed Critical 應答遺傳公司
Publication of HK1172931A1 publication Critical patent/HK1172931A1/zh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6827—Hybridisation assays for detection of mutation or polymorphism
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/112—Disease subtyping, staging or classification
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Pathology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Oncology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Paints Or Removers (AREA)
HK13100094.0A 2009-08-11 2013-01-04 可用於檢測 突變的方法、引物、探針和試劑盒 HK1172931A1 (zh)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US23305409P 2009-08-11 2009-08-11
US23707809P 2009-08-26 2009-08-26
US30179010P 2010-02-05 2010-02-05
PCT/US2010/044997 WO2011019704A2 (en) 2009-08-11 2010-08-10 Methods, primers, probes and kits useful for the detection of braf mutations

Publications (1)

Publication Number Publication Date
HK1172931A1 true HK1172931A1 (zh) 2013-05-03

Family

ID=43586772

Family Applications (1)

Application Number Title Priority Date Filing Date
HK13100094.0A HK1172931A1 (zh) 2009-08-11 2013-01-04 可用於檢測 突變的方法、引物、探針和試劑盒

Country Status (13)

Country Link
US (1) US20140248614A1 (zh)
EP (1) EP2464751B1 (zh)
JP (1) JP2013501523A (zh)
KR (1) KR20120099630A (zh)
CN (1) CN102575295B (zh)
AR (1) AR077844A1 (zh)
AU (1) AU2010282632A1 (zh)
CA (1) CA2770716A1 (zh)
HK (1) HK1172931A1 (zh)
IL (1) IL218021A0 (zh)
NZ (1) NZ598166A (zh)
TW (1) TW201111517A (zh)
WO (1) WO2011019704A2 (zh)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6153758B2 (ja) * 2012-04-20 2017-06-28 アークレイ株式会社 多型検出用プローブ、多型検出方法、薬効判定方法及び多型検出用キット
US10077474B2 (en) 2012-05-29 2018-09-18 Abbott Molecular, Inc. Method of designing primers, method of detecting single nucleotide polymorphisms (SNPs), method of distinguishing SNPs, and related primers, detectable oligonucleotides, and kits
CN102816851A (zh) * 2012-08-29 2012-12-12 苏州旷远生物分子技术有限公司 用于检测braf基因v600e突变的引物、探针、试剂盒及方法
CN102876784B (zh) * 2012-09-13 2014-11-19 周宏灏 焦磷酸测序法检测B-raf基因多态性的试剂盒及方法
EP2711432A1 (en) * 2012-09-21 2014-03-26 Genomica S.A.U. Method for detection of BRAF and PI3K mutations
WO2014105966A2 (en) 2012-12-27 2014-07-03 Quest Diagnostics Investments Incorporated Ddr2 mutations as targetable features of melanoma or basal cell carcinoma
CN103103269B (zh) * 2013-01-18 2015-07-15 陕西佰美基因股份有限公司 一种基于探针熔解技术准确检测braf基因突变的方法
CN105431550A (zh) * 2013-03-15 2016-03-23 雅培分子公司 多重等位基因检测
KR101378920B1 (ko) * 2013-04-18 2014-03-27 주식회사 현일바이오 Ｂｒａｆ 돌연변이의 선택적 검출 방법 및 이를 이용한 키트
JP2016527899A (ja) * 2013-08-14 2016-09-15 キアゲン マンスフィールド インコーポレイテッド Ｎｒａｓ核酸およびｂｒａｆ核酸のマルチプレックス解析のための組成物および方法
CN104017887A (zh) * 2014-06-18 2014-09-03 广州好芝生物科技有限公司 人类braf基因突变检测引物对和探针及其试剂盒
CN106796238B (zh) * 2014-07-11 2019-08-09 爱科谱迅病理研究公司 针对丝氨酸/苏氨酸蛋白激酶B-raf(BRAF)的SRM/MRM测定
CN105400900A (zh) * 2015-12-29 2016-03-16 杭州迪安生物技术有限公司 焦磷酸测序技术检测braf基因v600e微量突变试剂盒及其应用
CN105861691A (zh) * 2016-05-06 2016-08-17 北京晋祺生物科技有限公司 一种braf基因突变检测的引物组合物、试剂盒及方法
US20200360537A1 (en) * 2017-06-29 2020-11-19 Korea Advanced Institute Of Science And Technology A ganglioglioma-induced animal model and a method for diagnosing and treating ganglioglioma and related diseases
KR20190038464A (ko) * 2017-09-29 2019-04-08 (재)록원바이오융합연구재단 Ras/braf 돌연변이 검출용 조성물 및 이를 포함하는 키트
CN109161594A (zh) * 2018-08-17 2019-01-08 中山大学达安基因股份有限公司 一种检测braf基因突变的方法及其试剂盒
WO2022119423A1 (ko) * 2020-12-04 2022-06-09 주식회사 제노픽스 폐암 유전자 돌연변이 초고감도 선택적 증폭 방법 및 이를 위한 조성물

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2004337120A (ja) * 2003-05-19 2004-12-02 Chang Gung Univ 膀胱癌再発検査方法
US7745125B2 (en) * 2004-06-28 2010-06-29 Roche Molecular Systems, Inc. 2′-terminator related pyrophosphorolysis activated polymerization
CN101487051B (zh) * 2009-02-24 2011-07-20 广州益善生物技术有限公司 Braf基因突变的检测探针、液相芯片及其检测方法

Also Published As

Publication number Publication date
WO2011019704A3 (en) 2011-07-07
CN102575295B (zh) 2016-02-17
CA2770716A1 (en) 2011-02-17
WO2011019704A2 (en) 2011-02-17
JP2013501523A (ja) 2013-01-17
IL218021A0 (en) 2012-04-30
AR077844A1 (es) 2011-09-28
NZ598166A (en) 2014-03-28
KR20120099630A (ko) 2012-09-11
TW201111517A (en) 2011-04-01
US20140248614A1 (en) 2014-09-04
EP2464751A4 (en) 2013-07-03
AU2010282632A1 (en) 2012-03-08
EP2464751A2 (en) 2012-06-20
EP2464751B1 (en) 2017-05-24
CN102575295A (zh) 2012-07-11

Similar Documents

Publication Publication Date Title
HK1172931A1 (zh) 可用於檢測 突變的方法、引物、探針和試劑盒
HK1215300A1 (zh) 用於整合的樣品製備、反應和檢測的器械和方法
EP2569447A4 (en) ANALYZES FOR DETECTION OF GENOTYPE, MUTATIONS, AND / OR ANEUPLOIDIE
EP2547795A4 (en) COMPOSITIONS AND METHODS FOR SEARCHING GENOMIC CHARACTERISTICS
EP2430446A4 (en) METHOD AND COMPOSITIONS FOR DETECTING ANALYTES
ZA201106432B (en) Probes and primers for detection of chikungunya
EP2657706A4 (en) BIOMARKER FOR DISEASES RELATED TO COGNITIVE DYSFUNCTION AND METHOD FOR DETECTING DISEASES CONNECTED WITH COGNITIVE DYSFUNCTION THROUGH THIS BIOMARKER
EP2406613A4 (en) METHOD AND SYSTEM FOR MEASURING / DETECTING CHEMICAL LEAVES
EP2596343A4 (en) BIOSENSOR DEVICES AND METHOD THEREFOR
HK1184199A1 (zh) 生物傳感器測試元件以及其製造方法
EP2609429A4 (en) METHOD FOR DETECTING ANTI-HE4 ANTIBODIES AND METHODS FOR DIAGNOSIS AND / OR FORECASTING SUFFERING ASSOCIATED WITH HE4-EXPRESSING CELLS
EP2464737A4 (en) METHODS, KITS AND COMPOSITIONS FOR DETECTION OF NUCLEIC ACIDS WITH A SINGLE PROBE AT MULTIPLE TEMPERATURES
GB0915869D0 (en) Composition and assay method for the detection of patogenic bacteria
ZA201307104B (en) Compositions, methods, and kits for detecting and indentifying mycobactetia
EP2410052A4 (en) IN VITRO METHOD FOR THE DETECTION OF CANDIDA GLABRATA, DIAGNOSIS KIT AND USE THEREOF
HK1180726A1 (zh) 引物和探針
EP2257648A4 (en) OPTIMIZED PROBES AND PRIMERS AND METHOD FOR THEIR USE TO DETECT AND QUANTIFY THE BK VIRUS
EP2540838A4 (en) KITS FOR THE QUANTITATIVE DETECTION OF BRAF MUTATIONS
EP2567233A4 (en) METHOD AND KITS FOR DETERMINING THE RESISTANCE OF CELLS AGAINST SEVERAL ACTIVE SUBSTANCES
EP2520660A4 (en) KITS FOR THE QUANTITATIVE DETECTION OF K-RAS MUTATIONS
EP2495318A4 (en) PROBE FOR DETECTION OF POLYMORPHISM OF THE MPL GENE AND USE THEREOF
SG10201403780WA (en) Method and/or primers for the detection of mycobacterium tuberculosis
SG173803A1 (en) Probes and primers for detection of malaria
GB0806431D0 (en) Rapid detection of mycobacteria
HK1157395A1 (en) Primer and probe for detection of mycobacterium intracellulare, and method for detection of mycobacterium intracellulare using the primer or the probe

Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20200806