HK1118832A1 - Methods and compositions for detecting a drug resistant egfr mutant egfr - Google Patents
Methods and compositions for detecting a drug resistant egfr mutant egfrInfo
- Publication number
- HK1118832A1 HK1118832A1 HK08112871.1A HK08112871A HK1118832A1 HK 1118832 A1 HK1118832 A1 HK 1118832A1 HK 08112871 A HK08112871 A HK 08112871A HK 1118832 A1 HK1118832 A1 HK 1118832A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- egfr
- compositions
- detecting
- methods
- drug resistant
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/156—Polymorphic or mutational markers
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US65248805P | 2005-02-11 | 2005-02-11 | |
| PCT/US2006/005050 WO2006086777A2 (en) | 2005-02-11 | 2006-02-13 | Methods and compositions for detecting a drug resistant egfr mutant |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HK1118832A1 true HK1118832A1 (en) | 2009-02-20 |
Family
ID=36793833
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HK08112871.1A HK1118832A1 (en) | 2005-02-11 | 2008-11-24 | Methods and compositions for detecting a drug resistant egfr mutant egfr |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US8067175B2 (en) |
| EP (2) | EP2505591A1 (en) |
| JP (2) | JP4898710B2 (en) |
| CN (1) | CN101193905B (en) |
| CA (1) | CA2597673C (en) |
| ES (1) | ES2586410T3 (en) |
| HK (1) | HK1118832A1 (en) |
| WO (1) | WO2006086777A2 (en) |
Families Citing this family (70)
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| CA2597673C (en) * | 2005-02-11 | 2014-07-08 | Harold Varmus | Methods and compositions for detecting a drug resistant egfr mutant |
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| US11351168B1 (en) | 2008-06-27 | 2022-06-07 | Celgene Car Llc | 2,4-disubstituted pyrimidines useful as kinase inhibitors |
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| EP2542692B1 (en) | 2010-03-04 | 2016-08-24 | Carpén, Olli | Method for selecting patients for treatment with an egfr inhibitor |
| CA2767114A1 (en) | 2010-03-25 | 2011-09-29 | Bio-Rad Laboratories, Inc. | Droplet transport system for detection |
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| JP5956999B2 (en) | 2010-11-01 | 2016-07-27 | セルジーン アヴィロミクス リサーチ， インコーポレイテッド | Heteroaryl compounds and uses thereof |
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| ES2665013T3 (en) | 2010-11-10 | 2018-04-24 | Celgene Car Llc | EGFR selective mutant inhibitors and uses thereof |
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| US10260089B2 (en) | 2012-10-29 | 2019-04-16 | The Research Foundation Of The State University Of New York | Compositions and methods for recognition of RNA using triple helical peptide nucleic acids |
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| EP2964781B1 (en) | 2013-03-08 | 2018-01-10 | Roche Diagnostics GmbH | Egfr mutation blood testing |
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| WO2014147631A1 (en) | 2013-03-22 | 2014-09-25 | Natco Pharma Limited | Formulation comprising gefitinib as oral suspension |
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| GB201402996D0 (en) * | 2014-02-20 | 2014-04-09 | Vela Operations Pte Ltd | Variant analysis in high-throughput sequencing applications |
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| CN106498029B (en) * | 2016-06-20 | 2020-05-19 | 格诺思博生物科技南通有限公司 | Method for increasing diagnostic efficiency of T790M mutation of EGFR |
| JP2018088883A (en) * | 2016-12-06 | 2018-06-14 | 東洋紡株式会社 | Method of detecting epidermal growth factor receptor gene mutation |
| CN106811522A (en) * | 2016-12-26 | 2017-06-09 | 北京奥维森基因科技有限公司 | PCR primer group and its application and detection kit for detecting the pharmaceutical relevant gene resistance site with EGFP as target spot |
| US9980967B1 (en) | 2017-03-16 | 2018-05-29 | National Chiao Tung University | Method for overcoming drug resistance of EGFR mutation and cancerous stemness of human non-small cell lung carcinoma |
| CN106906295B (en) * | 2017-03-31 | 2020-12-08 | 天津诺禾致源生物信息科技有限公司 | Method and device for detecting gene point mutation by digital PCR |
| CN108546748A (en) * | 2017-04-05 | 2018-09-18 | 杭州丹威生物科技有限公司 | A kind of method and kit of detection nucleic acid |
| CN109722478A (en) * | 2017-10-31 | 2019-05-07 | 嘉兴雅康博医学检验所有限公司 | For detecting primer, probe and the kit of EGFR gene 2312-2313 mutation |
| CN111615561A (en) | 2018-03-15 | 2020-09-01 | 荣研化学株式会社 | Oligonucleotide probe for detecting single nucleotide polymorphism and cis-trans discrimination method |
| JOP20210233A1 (en) | 2019-02-26 | 2023-01-30 | Janssen Biotech Inc | Combination therapies and patient stratification with bispecific anti-egfr/c-met antibodies |
| CN111748026A (en) * | 2019-03-29 | 2020-10-09 | 天津亨佳生物科技发展有限公司 | Specific T cell receptor aiming at EGFR L858R gene mutation and application thereof |
| JOP20210304A1 (en) | 2019-05-14 | 2023-01-30 | Janssen Biotech Inc | Combination therapies with bispecific anti-egfr/c-met antibodies and third generation egfr tyrosine kinase inhibitors |
| KR20230039608A (en) * | 2020-05-07 | 2023-03-21 | 더 리전츠 오브 더 유니버시티 오브 캘리포니아 | Plasma and Saliva Liquid Biopsy Platform |
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-
2006
- 2006-02-13 CA CA2597673A patent/CA2597673C/en active Active
- 2006-02-13 ES ES06720702.7T patent/ES2586410T3/en active Active
- 2006-02-13 JP JP2007555320A patent/JP4898710B2/en active Active
- 2006-02-13 US US11/815,985 patent/US8067175B2/en active Active
- 2006-02-13 CN CN200680011674.5A patent/CN101193905B/en active Active
- 2006-02-13 WO PCT/US2006/005050 patent/WO2006086777A2/en active Application Filing
- 2006-02-13 EP EP12168082A patent/EP2505591A1/en not_active Ceased
- 2006-02-13 EP EP06720702.7A patent/EP1851339B1/en not_active Revoked
-
2008
- 2008-11-24 HK HK08112871.1A patent/HK1118832A1/en unknown
-
2011
- 2011-10-17 US US13/275,161 patent/US8501413B2/en active Active
- 2011-11-16 JP JP2011250657A patent/JP2012070746A/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| US8067175B2 (en) | 2011-11-29 |
| US20100173285A1 (en) | 2010-07-08 |
| JP2012070746A (en) | 2012-04-12 |
| CA2597673A1 (en) | 2006-08-17 |
| EP1851339B1 (en) | 2016-05-18 |
| ES2586410T3 (en) | 2016-10-14 |
| JP2008529532A (en) | 2008-08-07 |
| EP1851339A2 (en) | 2007-11-07 |
| JP4898710B2 (en) | 2012-03-21 |
| WO2006086777A2 (en) | 2006-08-17 |
| CA2597673C (en) | 2014-07-08 |
| CN101193905B (en) | 2014-06-25 |
| CN101193905A (en) | 2008-06-04 |
| US20120077201A1 (en) | 2012-03-29 |
| WO2006086777A3 (en) | 2007-11-22 |
| EP2505591A1 (en) | 2012-10-03 |
| US8501413B2 (en) | 2013-08-06 |
| EP1851339A4 (en) | 2009-05-27 |
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