HK1114387A1 - Pyrimidine derivatives for use as anticancer agents - Google Patents

Pyrimidine derivatives for use as anticancer agents

Info

Publication number
HK1114387A1
HK1114387A1 HK08104308.1A HK08104308A HK1114387A1 HK 1114387 A1 HK1114387 A1 HK 1114387A1 HK 08104308 A HK08104308 A HK 08104308A HK 1114387 A1 HK1114387 A1 HK 1114387A1
Authority
HK
Hong Kong
Prior art keywords
anticancer agents
pyrimidine derivatives
substituents
man
text
Prior art date
Application number
HK08104308.1A
Other languages
English (en)
Inventor
Andrew Peter Thomas
Thorsten Nowak
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB0506883A external-priority patent/GB0506883D0/en
Priority claimed from GB0525953A external-priority patent/GB0525953D0/en
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of HK1114387A1 publication Critical patent/HK1114387A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
HK08104308.1A 2005-04-05 2008-04-16 Pyrimidine derivatives for use as anticancer agents HK1114387A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB0506883A GB0506883D0 (en) 2005-04-05 2005-04-05 Chemical compounds
GB0525953A GB0525953D0 (en) 2005-12-21 2005-12-21 Chemical compounds
PCT/GB2006/001195 WO2006106307A1 (en) 2005-04-05 2006-03-31 Pyrimidine derivatives for use as anticancer agents

Publications (1)

Publication Number Publication Date
HK1114387A1 true HK1114387A1 (en) 2008-10-31

Family

ID=36641343

Family Applications (1)

Application Number Title Priority Date Filing Date
HK08104308.1A HK1114387A1 (en) 2005-04-05 2008-04-16 Pyrimidine derivatives for use as anticancer agents

Country Status (19)

Country Link
US (1) US20080167297A1 (xx)
EP (1) EP1869032B8 (xx)
JP (1) JP2008534662A (xx)
KR (1) KR20070116994A (xx)
AT (1) ATE404554T1 (xx)
AU (1) AU2006231116A1 (xx)
BR (1) BRPI0609965A2 (xx)
CA (1) CA2602372A1 (xx)
DE (1) DE602006002271D1 (xx)
DK (1) DK1869032T3 (xx)
ES (1) ES2310406T3 (xx)
HK (1) HK1114387A1 (xx)
HR (1) HRP20080505T3 (xx)
IL (1) IL186034A0 (xx)
MX (1) MX2007012345A (xx)
NO (1) NO20074869L (xx)
PT (1) PT1869032E (xx)
SI (1) SI1869032T1 (xx)
WO (1) WO2006106307A1 (xx)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20110131302A (ko) * 2009-03-23 2011-12-06 엠에스디 가부시키가이샤 오로라 ａ 선택적 억제 작용을 갖는 신규한 아미노피리딘 유도체
AU2010229140A1 (en) * 2009-03-24 2011-11-10 Msd K.K. Novel aminopyridine derivatives having Aurora A selective inhibitory action
US20110053916A1 (en) 2009-08-14 2011-03-03 Vertex Pharmaceuticals Incorporated Pyrimidine compounds as tuberculosis inhibitors
AU2012299080B2 (en) * 2011-08-25 2016-03-17 Merck Sharp & Dohme Llc Pyrimidine PDE10 inhibitors
WO2023164611A1 (en) * 2022-02-25 2023-08-31 Nalo Therapeutics Modulators of myc family proto-oncogene protein
WO2023163712A1 (en) * 2022-02-25 2023-08-31 Nalo Therapeutics Modulators of myc family proto-oncogene protein

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2426180A1 (de) * 1974-05-29 1975-12-18 Bayer Ag Verfahren zum faerben von polyurethankunststoffen
DE60120193T2 (de) * 2000-09-15 2007-03-29 Vertex Pharmaceuticals Inc., Cambridge Pyrazolverbindungen als protein-kinasehemmer
ATE528303T1 (de) * 2000-12-21 2011-10-15 Vertex Pharma Pyrazoleverbindungen als proteinkinasehemmer
US6939874B2 (en) * 2001-08-22 2005-09-06 Amgen Inc. Substituted pyrimidinyl derivatives and methods of use
CA2507100C (en) * 2002-11-21 2012-10-09 Chiron Corporation 2,4,6-trisubstituted pyrimidines as phosphotidylinositol (pi) 3-kinase inhibitors and their use in the treatment of cancer
AU2004283137A1 (en) * 2003-10-17 2005-05-06 Astrazeneca Ab 4-(pyrazol-3-ylamino) pyrimidine derivatives for use in the treatment of cancer

Also Published As

Publication number Publication date
IL186034A0 (en) 2008-02-09
WO2006106307A1 (en) 2006-10-12
EP1869032B1 (en) 2008-08-13
CA2602372A1 (en) 2006-10-12
EP1869032B8 (en) 2009-03-25
BRPI0609965A2 (pt) 2011-10-11
AU2006231116A1 (en) 2006-10-12
ATE404554T1 (de) 2008-08-15
PT1869032E (pt) 2008-10-21
DK1869032T3 (da) 2008-11-10
SI1869032T1 (sl) 2008-12-31
DE602006002271D1 (de) 2008-09-25
KR20070116994A (ko) 2007-12-11
ES2310406T3 (es) 2009-01-01
JP2008534662A (ja) 2008-08-28
NO20074869L (no) 2007-11-02
US20080167297A1 (en) 2008-07-10
EP1869032A1 (en) 2007-12-26
MX2007012345A (es) 2007-11-23
HRP20080505T3 (en) 2008-11-30

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Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20130331