HK1058665A1 - Optically pure camptothecin analogues. - Google Patents

Optically pure camptothecin analogues.

Info

Publication number
HK1058665A1
HK1058665A1 HK04101371A HK04101371A HK1058665A1 HK 1058665 A1 HK1058665 A1 HK 1058665A1 HK 04101371 A HK04101371 A HK 04101371A HK 04101371 A HK04101371 A HK 04101371A HK 1058665 A1 HK1058665 A1 HK 1058665A1
Authority
HK
Hong Kong
Prior art keywords
optically pure
camptothecin analogues
pure camptothecin
analogues
optically
Prior art date
Application number
HK04101371A
Inventor
Jean-Bernard Cazaux
Olivier Lavergne
Christine Le Breton
Eric Manginot
Dennis Bigg
Original Assignee
Conseil De Rech S Et D Applica
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Conseil De Rech S Et D Applica filed Critical Conseil De Rech S Et D Applica
Publication of HK1058665A1 publication Critical patent/HK1058665A1/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D491/00Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/22Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains four or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D491/00Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Steroid Compounds (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
HK04101371A 1997-08-29 2004-02-25 Optically pure camptothecin analogues. HK1058665A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9710785A FR2768431B1 (en) 1997-08-29 1997-08-29 NOVEL OPTICALLY PURE CAMPTOTHECIN ANALOGS, A NEW OPTICALLY PURE SYNTHESIS INTERMEDIATE AND PROCESS FOR PREPARING THE SAME

Publications (1)

Publication Number Publication Date
HK1058665A1 true HK1058665A1 (en) 2004-05-28

Family

ID=9510590

Family Applications (2)

Application Number Title Priority Date Filing Date
HK01102373A HK1031732A1 (en) 1997-08-29 2001-04-03 Optically pure camptothecin analogues, optically pure synthesis intermediate and method for preparing same
HK04101371A HK1058665A1 (en) 1997-08-29 2004-02-25 Optically pure camptothecin analogues.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
HK01102373A HK1031732A1 (en) 1997-08-29 2001-04-03 Optically pure camptothecin analogues, optically pure synthesis intermediate and method for preparing same

Country Status (26)

Country Link
EP (2) EP1378512A1 (en)
JP (1) JP2001514261A (en)
KR (1) KR100570254B1 (en)
CN (3) CN1195758C (en)
AR (1) AR016856A1 (en)
AT (1) ATE253069T1 (en)
AU (1) AU760863B2 (en)
BR (1) BR9811405A (en)
CA (1) CA2301739C (en)
CZ (1) CZ297896B6 (en)
DE (1) DE69819340T2 (en)
DK (1) DK1007527T3 (en)
ES (1) ES2209196T3 (en)
FR (1) FR2768431B1 (en)
HK (2) HK1031732A1 (en)
HR (1) HRP20000110A2 (en)
HU (1) HUP0003429A3 (en)
IL (2) IL134437A0 (en)
NO (1) NO324882B1 (en)
NZ (1) NZ502862A (en)
PL (1) PL195289B1 (en)
PT (1) PT1007527E (en)
RU (1) RU2233283C2 (en)
TW (1) TW419479B (en)
WO (1) WO1999011646A1 (en)
ZA (1) ZA987445B (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2790261B1 (en) * 1999-02-26 2004-09-10 Sod Conseils Rech Applic NOVEL OPTICALLY PURE CAMPTOTHECIN ANALOGS AND PROCESSES FOR THEIR PREPARATION
US6207832B1 (en) 1999-04-09 2001-03-27 University Of Pittsburgh Camptothecin analogs and methods of preparation thereof
US6372906B1 (en) 2001-04-12 2002-04-16 University Of Pittsburgh Synthesis of silyl camptothecins and silyl homocamptothecins
US6723853B2 (en) 2001-08-27 2004-04-20 University Of Pittsburgh Intermediates and methods of preparation of intermediates in the enantiomeric synthesis of (20R)homocamptothecins and the enantiomeric synthesis of (20R)homocamptothecins
CN100408582C (en) * 2004-02-12 2008-08-06 中国人民解放军第二军医大学 Homocamptoth-ecine compounds, their preparation process and use
CA2580747A1 (en) * 2004-09-21 2006-03-30 Societe De Conseils De Recherches Et D'applications Scientifiques (S.C.R .A.S.) Novel processes for the production of useful intermediates
CN100465175C (en) * 2005-11-29 2009-03-04 中国人民解放军第二军医大学 7-bit substituted comptothecine kind compound and pharmaceutical use thereof

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5459269A (en) * 1992-06-18 1995-10-17 North Carolina State University 14-halo-camptothecins
EP0835258B1 (en) * 1995-06-21 2002-09-25 Societe De Conseils De Recherches Et D'applications Scientifiques (S.C.R.A.S.) Novel camptothecin analogues, preparation methods therefor, use thereof as drugs, and pharmaceutical compositions containing said analogues

Also Published As

Publication number Publication date
FR2768431A1 (en) 1999-03-19
EP1378512A1 (en) 2004-01-07
DE69819340D1 (en) 2003-12-04
KR20010023394A (en) 2001-03-26
NO324882B1 (en) 2007-12-27
CA2301739A1 (en) 1999-03-11
CZ2000711A3 (en) 2000-08-16
ES2209196T3 (en) 2004-06-16
HK1031732A1 (en) 2001-06-22
NO20000995L (en) 2000-02-28
RU2233283C2 (en) 2004-07-27
FR2768431B1 (en) 2000-03-24
DK1007527T3 (en) 2004-03-08
CN1440973A (en) 2003-09-10
AR016856A1 (en) 2001-08-01
IL134437A (en) 2006-08-01
ATE253069T1 (en) 2003-11-15
AU8989698A (en) 1999-03-22
CN1268948A (en) 2000-10-04
WO1999011646A1 (en) 1999-03-11
PT1007527E (en) 2004-03-31
ZA987445B (en) 1999-02-17
IL134437A0 (en) 2001-04-30
CA2301739C (en) 2009-11-17
PL195289B1 (en) 2007-08-31
PL338835A1 (en) 2000-11-20
AU760863B2 (en) 2003-05-22
NO20000995D0 (en) 2000-02-28
CN1195758C (en) 2005-04-06
NZ502862A (en) 2002-10-25
HRP20000110A2 (en) 2001-02-28
DE69819340T2 (en) 2004-08-19
BR9811405A (en) 2000-08-29
JP2001514261A (en) 2001-09-11
TW419479B (en) 2001-01-21
CN1440972A (en) 2003-09-10
HUP0003429A1 (en) 2001-07-30
CN1104434C (en) 2003-04-02
EP1007527A1 (en) 2000-06-14
EP1007527B1 (en) 2003-10-29
CZ297896B6 (en) 2007-04-25
KR100570254B1 (en) 2006-04-12
HUP0003429A3 (en) 2002-11-28

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Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20110807