HK1047714A1 - Systems and methods for aerosolizing pharmaceutical formulations - Google Patents

Systems and methods for aerosolizing pharmaceutical formulations

Info

Publication number
HK1047714A1
HK1047714A1 HK02108262A HK02108262A HK1047714A1 HK 1047714 A1 HK1047714 A1 HK 1047714A1 HK 02108262 A HK02108262 A HK 02108262A HK 02108262 A HK02108262 A HK 02108262A HK 1047714 A1 HK1047714 A1 HK 1047714A1
Authority
HK
Hong Kong
Prior art keywords
systems
methods
pharmaceutical formulations
aerosolizing
aerosolizing pharmaceutical
Prior art date
Application number
HK02108262A
Other languages
English (en)
Inventor
Carlos Schuler
Steve Paboojian
Derrick J Tuttle
Adrian E Smith
Dennis R Rasmussen
Aneesh Bakshi
Andrew Clark
Brian R S Ward
William W Alston Jr
Kevin S Nason
Original Assignee
Nektar Therapeutics
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nektar Therapeutics filed Critical Nektar Therapeutics
Publication of HK1047714A1 publication Critical patent/HK1047714A1/xx

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0028Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0001Details of inhalators; Constructional features thereof
    • A61M15/002Details of inhalators; Constructional features thereof with air flow regulating means
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0028Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/003Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using capsules, e.g. to be perforated or broken-up
    • A61M15/0033Details of the piercing or cutting means
    • A61M15/0035Piercing means
    • A61M15/0036Piercing means hollow piercing means
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0028Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/0045Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters
    • A61M15/0046Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters characterized by the type of carrier
    • A61M15/0051Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters characterized by the type of carrier the dosages being arranged on a tape, e.g. strips
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0065Inhalators with dosage or measuring devices
    • A61M15/0068Indicating or counting the number of dispensed doses or of remaining doses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0065Inhalators with dosage or measuring devices
    • A61M15/0068Indicating or counting the number of dispensed doses or of remaining doses
    • A61M15/0083Timers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0091Inhalators mechanically breath-triggered
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0091Inhalators mechanically breath-triggered
    • A61M15/0093Inhalators mechanically breath-triggered without arming or cocking, e.g. acting directly on the delivery valve
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0091Inhalators mechanically breath-triggered
    • A61M15/0096Hindering inhalation before activation of the dispenser
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
    • A61M16/04Tracheal tubes
    • A61M16/0488Mouthpieces; Means for guiding, securing or introducing the tubes
    • A61M16/049Mouthpieces
    • A61M16/0493Mouthpieces with means for protecting the tube from damage caused by the patient's teeth, e.g. bite block
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
    • A61M16/04Tracheal tubes
    • A61M16/0488Mouthpieces; Means for guiding, securing or introducing the tubes
    • A61M16/049Mouthpieces
    • A61M16/0495Mouthpieces with tongue depressors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
    • A61M16/08Bellows; Connecting tubes ; Water traps; Patient circuits
    • A61M16/0866Passive resistors therefor
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
    • A61M16/20Valves specially adapted to medical respiratory devices
    • A61M16/201Controlled valves
    • A61M16/206Capsule valves, e.g. mushroom, membrane valves
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
    • A61M16/20Valves specially adapted to medical respiratory devices
    • A61M16/208Non-controlled one-way valves, e.g. exhalation, check, pop-off non-rebreathing valves
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00Special media to be introduced, removed or treated
    • A61M2202/06Solids
    • A61M2202/064Powder

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Anesthesiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Emergency Medicine (AREA)
  • Biophysics (AREA)
  • Otolaryngology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Containers And Packaging Bodies Having A Special Means To Remove Contents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Cosmetics (AREA)
  • Medicines Containing Plant Substances (AREA)
HK02108262A 1999-06-30 2002-11-14 Systems and methods for aerosolizing pharmaceutical formulations HK1047714A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US14179399P 1999-06-30 1999-06-30
US19806000P 2000-04-18 2000-04-18
PCT/US2000/018084 WO2001000263A2 (en) 1999-06-30 2000-06-29 Systems and methods for aerosolizing pharmaceutical formulations

Publications (1)

Publication Number Publication Date
HK1047714A1 true HK1047714A1 (en) 2003-03-07

Family

ID=26839451

Family Applications (2)

Application Number Title Priority Date Filing Date
HK02108262A HK1047714A1 (en) 1999-06-30 2002-11-14 Systems and methods for aerosolizing pharmaceutical formulations
HK02108960.7A HK1047408A1 (zh) 1999-06-30 2002-12-11 霧化藥物製劑的系統和方法

Family Applications After (1)

Application Number Title Priority Date Filing Date
HK02108960.7A HK1047408A1 (zh) 1999-06-30 2002-12-11 霧化藥物製劑的系統和方法

Country Status (42)

Country Link
US (2) US6606992B1 (no)
EP (1) EP1212111B1 (no)
JP (2) JP2003503117A (no)
KR (2) KR20080081376A (no)
CN (1) CN1217713C (no)
AP (1) AP1611A (no)
AT (1) ATE474615T1 (no)
AU (1) AU771926B2 (no)
BG (1) BG106218A (no)
BR (1) BR0012013A (no)
CA (1) CA2377625C (no)
CO (1) CO5280133A1 (no)
CZ (1) CZ20014723A3 (no)
DE (1) DE60044719D1 (no)
DZ (1) DZ3169A1 (no)
EA (1) EA003153B1 (no)
EE (1) EE04631B1 (no)
ES (1) ES2347410T3 (no)
GE (1) GEP20043258B (no)
HK (2) HK1047714A1 (no)
HR (1) HRP20010936A2 (no)
HU (1) HU225182B1 (no)
IL (2) IL147303A0 (no)
IS (1) IS6197A (no)
LT (1) LT4943B (no)
LV (1) LV12804B (no)
MA (1) MA26800A1 (no)
MX (1) MXPA01012789A (no)
MY (1) MY125534A (no)
NO (1) NO20016277L (no)
NZ (1) NZ516098A (no)
PA (1) PA8497901A1 (no)
PE (1) PE20010356A1 (no)
PL (1) PL205905B1 (no)
PT (1) PT1212111E (no)
RS (1) RS50349B (no)
SG (1) SG135936A1 (no)
TN (1) TNSN00148A1 (no)
TR (3) TR200202521T2 (no)
TW (1) TW470655B (no)
UY (1) UY26232A1 (no)
WO (1) WO2001000263A2 (no)

Families Citing this family (177)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5823179A (en) 1996-02-13 1998-10-20 1263152 Ontario Inc. Nebulizer apparatus and method
US20060165606A1 (en) 1997-09-29 2006-07-27 Nektar Therapeutics Pulmonary delivery particles comprising water insoluble or crystalline active agents
US6217895B1 (en) 1999-03-22 2001-04-17 Control Delivery Systems Method for treating and/or preventing retinal diseases with sustained release corticosteroids
US9006175B2 (en) 1999-06-29 2015-04-14 Mannkind Corporation Potentiation of glucose elimination
US7305986B1 (en) 1999-07-23 2007-12-11 Mannkind Corporation Unit dose capsules for use in a dry powder inhaler
US7464706B2 (en) * 1999-07-23 2008-12-16 Mannkind Corporation Unit dose cartridge and dry powder inhaler
US20010029947A1 (en) * 1999-12-17 2001-10-18 Steve Paboojian Receptacles to facilitate the extraction of powders
US20010035184A1 (en) 1999-12-17 2001-11-01 Carlos Schuler Systems and methods for treating packaged powders
CA2826724C (en) 2000-04-11 2016-02-02 Trudell Medical International Aerosol delivery apparatus with positive expiratory pressure capacity
US6375972B1 (en) 2000-04-26 2002-04-23 Control Delivery Systems, Inc. Sustained release drug delivery devices, methods of use, and methods of manufacturing thereof
US7871598B1 (en) 2000-05-10 2011-01-18 Novartis Ag Stable metal ion-lipid powdered pharmaceutical compositions for drug delivery and methods of use
US6668827B2 (en) * 2000-05-16 2003-12-30 Nektar Therapeutics Systems devices and methods for opening receptacles having a powder to be fluidized
GB0024793D0 (en) * 2000-10-10 2000-11-22 Innovata Biomed Ltd Diaphragm
US6443152B1 (en) * 2001-01-12 2002-09-03 Becton Dickinson And Company Medicament respiratory delivery device
US6722364B2 (en) * 2001-01-12 2004-04-20 Becton, Dickinson And Company Medicament inhalation delivery devices and methods for using the same
US6782887B2 (en) * 2001-01-12 2004-08-31 Becton, Dickinson And Company Medicament respiratory delivery device and cartridge
CA2809180C (en) 2001-03-20 2015-06-02 Trudell Medical International Nebulizer apparatus with an adjustable fluid orifice
US7905230B2 (en) * 2001-05-09 2011-03-15 Novartis Ag Metered dose inhaler with lockout
US6554023B2 (en) 2001-06-13 2003-04-29 Baxter International Inc. Vacuum demand flow valve
US6550493B2 (en) 2001-06-13 2003-04-22 Baxter International Inc. Vacuum demand valve
EP1399210B1 (en) * 2001-06-20 2013-08-21 Novartis AG Aerosolization device
GB2380946A (en) * 2001-08-31 2003-04-23 Medic Aid Ltd Nebuliser arrangement
ATE298600T1 (de) 2001-10-18 2005-07-15 Pari Gmbh Inhalationstherapievorrichtung
PT1458360E (pt) 2001-12-19 2011-07-13 Novartis Ag Derivados de indole como agonistas do recetor s1p1
EP1472140A1 (en) * 2001-12-21 2004-11-03 Nektar Therapeutics Apparatus and method for sealing cavities
US6994083B2 (en) 2001-12-21 2006-02-07 Trudell Medical International Nebulizer apparatus and method
WO2003057593A1 (en) * 2001-12-21 2003-07-17 Nektar Therapeutics Capsule package with moisture barrier
US8116860B2 (en) * 2002-03-11 2012-02-14 Altea Therapeutics Corporation Transdermal porator and patch system and method for using same
DE60318938T2 (de) 2002-03-20 2009-01-22 Mannkind Corp., Valencia Inhalationsgerät
US20030205226A1 (en) 2002-05-02 2003-11-06 Pre Holding, Inc. Aerosol medication inhalation system
US8871241B2 (en) 2002-05-07 2014-10-28 Psivida Us, Inc. Injectable sustained release delivery devices
US6904908B2 (en) 2002-05-21 2005-06-14 Trudell Medical International Visual indicator for an aerosol medication delivery apparatus and system
US7185651B2 (en) * 2002-06-18 2007-03-06 Nektar Therapeutics Flow regulator for aerosol drug delivery and methods
US6941980B2 (en) * 2002-06-27 2005-09-13 Nektar Therapeutics Apparatus and method for filling a receptacle with powder
JP2004195191A (ja) * 2002-10-22 2004-07-15 Akihiko Miyamoto 呼子付喘息治療薬吸入器
WO2004054606A1 (en) * 2002-12-13 2004-07-01 Pfizer Products Inc. Method of decreasing hepatic glucose output in diabetic patients
USD499793S1 (en) 2003-03-17 2004-12-14 Baxter International Inc. Valve
WO2004103445A1 (fr) * 2003-05-21 2004-12-02 Jean-Marc Aiache Dispositif d'inhalation de poudre
AU2003260166A1 (en) * 2003-09-16 2005-04-06 Injet Digital Aerosols Limited Inhaler with air flow regulation
AU2006225241B2 (en) * 2003-09-24 2008-07-17 Tianda Pharmaceuticals (Australia) Pty Limited Medication Holder
AU2004273547B2 (en) * 2003-09-24 2006-07-06 Tianda Pharmaceuticals (Australia) Pty Ltd Medication holder
EP1675636A4 (en) 2003-09-24 2009-12-23 Medi Stream Pty Ltd MEDICATION HOLDER
GB2407042B (en) 2003-10-17 2007-10-24 Vectura Ltd Inhaler
DE10352277A1 (de) * 2003-11-08 2005-06-02 Boehringer Ingelheim Pharma Gmbh & Co. Kg Pulverinhalator
JP4601627B2 (ja) * 2004-01-16 2010-12-22 バイオデル, インコーポレイテッド 舌下薬物送達デバイス
US7723306B2 (en) 2004-05-10 2010-05-25 Boehringer Ingelheim Pharma Gmbh & Co. Kg Spray-dried powder comprising at least one 1,4 O-linked saccharose-derivative and methods for their preparation
US7611709B2 (en) 2004-05-10 2009-11-03 Boehringer Ingelheim Pharma Gmbh And Co. Kg 1,4 O-linked saccharose derivatives for stabilization of antibodies or antibody derivatives
US7727962B2 (en) 2004-05-10 2010-06-01 Boehringer Ingelheim Pharma Gmbh & Co. Kg Powder comprising new compositions of oligosaccharides and methods for their preparation
BE1015883A3 (fr) * 2004-06-08 2005-10-04 Occhio Procede et dispositif de dispersion de poudres seches.
JP4695940B2 (ja) * 2004-08-02 2011-06-08 キヤノン株式会社 吸入装置
DK1786784T3 (da) 2004-08-20 2011-02-14 Mannkind Corp Katalyse af diketopiperazinsyntese
JP4990142B2 (ja) 2004-08-23 2012-08-01 マンカインド コーポレイション 薬物送達のためのジケトピペラジン塩、ジケトモルホリン塩、又はジケトジオキサン塩
FR2877925B1 (fr) * 2004-11-16 2008-09-19 Valois Sas Dispositif de distribution de produit fluide.
GB0427028D0 (en) * 2004-12-09 2005-01-12 Cambridge Consultants Dry powder inhalers
GB0428169D0 (en) * 2004-12-23 2005-01-26 3M Innovative Properties Co Pressurized inhalation devices
FR2881119B1 (fr) * 2005-01-25 2010-07-30 Valois Sas Dispositif de distribution de produit fluide.
US20070012316A1 (en) * 2005-07-14 2007-01-18 Joann Truza Disposable compact rescue inhaler
US10244793B2 (en) 2005-07-19 2019-04-02 Juul Labs, Inc. Devices for vaporization of a substance
US8763605B2 (en) 2005-07-20 2014-07-01 Manta Devices, Llc Inhalation device
US20070023042A1 (en) * 2005-07-28 2007-02-01 Lee Lanny R Demand free air flow inhalator
HUE028691T2 (en) 2005-09-14 2016-12-28 Mannkind Corp A method for formulating a drug based on increasing the affinity of crystalline microparticle surfaces towards active ingredients
CA2623256A1 (en) * 2005-09-29 2007-04-12 Nektar Therapeutics Receptacles and kits, such as for dry powder packaging
AU2007216966C1 (en) 2006-02-22 2014-03-20 Mannkind Corporation A method for improving the pharmaceutic properties of microparticles comprising diketopiperazine and an active agent
GB0611656D0 (en) * 2006-06-13 2006-07-19 Cambridge Consultants Dry powder inhalers
WO2008008021A1 (en) * 2006-07-14 2008-01-17 Astrazeneca Ab Inhalation system and delivery device for the administration of a drug in the form of dry powder.
WO2008051471A2 (en) * 2006-10-19 2008-05-02 Haroutunian Greg G Flow modification device
US9155849B2 (en) 2006-10-19 2015-10-13 G Greg Haroutunian Flow modification device
MY151609A (en) 2006-10-25 2014-06-30 Novartis Ag Powder dispersion apparatus, method of making and using the apparatus, and components that can be used on the apparatus and other devices
CA2675030C (en) 2007-01-09 2015-06-09 Mystic Pharmaceuticals, Inc. Intranasal cartridge devices
WO2008101991A1 (en) * 2007-02-21 2008-08-28 Novo Nordisk A/S Breath actuation mechanism for an aerosol generating device
WO2008101992A1 (en) * 2007-02-21 2008-08-28 Novo Nordisk A/S Aerosol generating device with air flow control
WO2008131412A1 (en) * 2007-04-23 2008-10-30 Goodhealth, Llc Passive treatment device
US9248076B2 (en) 2007-05-16 2016-02-02 Mystic Pharmaceuticals, Inc. Dose dispensing containers
US8683995B2 (en) 2007-05-16 2014-04-01 Mystic Pharmaceuticals, Inc. Dose dispensing containers
CA2688689C (en) 2007-05-16 2015-06-30 Mystic Pharmaceuticals, Inc. Combination unit dose dispensing containers
US11224704B2 (en) 2007-07-06 2022-01-18 Manta Devices, Llc Dose delivery device for inhalation
EP3453418A1 (en) * 2007-07-06 2019-03-13 Manta Devices, LLC Delivery device and related methods
ES2398921T3 (es) * 2007-08-02 2013-03-22 Activaero Gmbh Dispositivo y sistema para dirigir partículas aerosolizadas a un área específica de los pulmones
JP2010538925A (ja) * 2007-09-14 2010-12-16 ミスティック ファーマシューティカルズ, インコーポレイテッド 深絞り容器成形方法
AU2008317307A1 (en) * 2007-10-25 2009-04-30 Novartis Ag Powder conditioning of unit dose drug packages
DE102007056263A1 (de) 2007-11-22 2009-05-28 Siegfried Generics International Ag Dosiervorrichtung zur Inhalierung einer pulverförmigen Substanz
PT2230934E (pt) 2007-12-14 2012-11-20 Aerodesigns Inc Distribuir produtos alimentares aerossolizáveis
GB0802028D0 (en) * 2008-02-05 2008-03-12 Dunne Stephen T Powder inhaler flow regulator
ES2655921T3 (es) 2008-06-13 2018-02-22 Mannkind Corporation Un inhalador de polvo seco y sistema para administración de fármacos
US8485180B2 (en) 2008-06-13 2013-07-16 Mannkind Corporation Dry powder drug delivery system
ES2904623T3 (es) 2008-06-20 2022-04-05 Mannkind Corp Aparato interactivo para establecer un perfil en tiempo real de esfuerzos de inhalación
WO2010011329A2 (en) * 2008-07-23 2010-01-28 Map Pharmaceuticals, Inc. The delivery of powdered drug via inhalation
TWI532497B (zh) 2008-08-11 2016-05-11 曼凱公司 超快起作用胰島素之用途
US8314106B2 (en) 2008-12-29 2012-11-20 Mannkind Corporation Substituted diketopiperazine analogs for use as drug delivery agents
EP2405963B1 (en) 2009-03-11 2013-11-06 MannKind Corporation Apparatus, system and method for measuring resistance of an inhaler
WO2010144789A2 (en) 2009-06-12 2010-12-16 Mannkind Corporation Diketopiperazine microparticles with defined specific surface areas
US8495998B2 (en) 2009-06-17 2013-07-30 British American Tobacco (Investments) Limited Inhaler
EP2283887B1 (de) * 2009-08-06 2012-07-04 Activaero GmbH Vorrichtung zur Flussbegrenzung bei niedrigen Differenzdrücken
WO2011056889A1 (en) 2009-11-03 2011-05-12 Mannkind Corporation An apparatus and method for simulating inhalation efforts
CN102711884B (zh) 2009-12-04 2014-07-16 皇家飞利浦电子股份有限公司 包括用于气雾药物输送的可调节带台阶的管嘴的装置和方法
US8974771B2 (en) * 2010-03-09 2015-03-10 Penn-Century, Inc. Apparatus and method for aerosol delivery to the lungs or other locations of the body
US9044256B2 (en) * 2010-05-19 2015-06-02 Board Of Regents, The University Of Texas System Medical devices, apparatuses, systems, and methods
KR20130117755A (ko) 2010-06-21 2013-10-28 맨카인드 코포레이션 건조 분말 약물 운반 시스템 및 방법
US8689439B2 (en) 2010-08-06 2014-04-08 Abbott Laboratories Method for forming a tube for use with a pump delivery system
US9757528B2 (en) 2010-08-23 2017-09-12 Darren Rubin Nebulizer having different negative pressure threshold settings
CA3071911C (en) 2010-08-23 2023-01-17 Darren Rubin Systems and methods of aerosol delivery with airflow regulation
US8377000B2 (en) 2010-10-01 2013-02-19 Abbott Laboratories Enteral feeding apparatus having a feeding set
US8377001B2 (en) 2010-10-01 2013-02-19 Abbott Laboratories Feeding set for a peristaltic pump system
CN102553038B (zh) * 2010-12-17 2014-07-02 陈庆堂 药粉吸嘴放置盒
PL2654864T3 (pl) 2010-12-22 2021-07-12 Syqe Medical Ltd. System dostarczania leku
CN105667994B (zh) 2011-04-01 2018-04-06 曼金德公司 用于药物药盒的泡罩包装
IN2014CN00024A (no) * 2011-06-06 2015-08-21 Trudell Medical Int
WO2012174472A1 (en) 2011-06-17 2012-12-20 Mannkind Corporation High capacity diketopiperazine microparticles
WO2013063160A1 (en) 2011-10-24 2013-05-02 Mannkind Corporation Methods and compositions for treating pain
CA2859684C (en) * 2011-11-18 2020-02-11 Colin Dunlop A method and apparatus for facilitating delivery of anaesthetic
KR20140103939A (ko) 2011-12-16 2014-08-27 노파르티스 아게 흡입 프로파일-비의존적 약물 전달을 위한 에어로졸화 장치
US9364622B2 (en) 2012-04-20 2016-06-14 Fsc Laboratories, Inc. Inhalation devices and systems and methods including the same
DE102012103482A1 (de) * 2012-04-20 2013-10-24 Alfred Von Schuckmann Vorrichtung zum Inhalieren pulverförmiger Substanzen
CN104470569B (zh) 2012-06-28 2018-04-27 美国政府(由卫生和人类服务部的部长所代表) 用于疫苗和其它治疗试剂的鼻干粉递送***
CN108057154B (zh) 2012-07-12 2021-04-16 曼金德公司 干粉药物输送***和方法
US10159644B2 (en) 2012-10-26 2018-12-25 Mannkind Corporation Inhalable vaccine compositions and methods
JP6523247B2 (ja) 2013-03-15 2019-05-29 マンカインド コーポレイション 微結晶性ジケトピペラジン粒子の製造方法および乾燥粉末組成物の製造方法
EP3021834A1 (en) 2013-07-18 2016-05-25 MannKind Corporation Heat-stable dry powder pharmaceutical compositions and methods
EP3030294B1 (en) 2013-08-05 2020-10-07 MannKind Corporation Insufflation apparatus
US10076139B2 (en) 2013-12-23 2018-09-18 Juul Labs, Inc. Vaporizer apparatus
US10159282B2 (en) 2013-12-23 2018-12-25 Juul Labs, Inc. Cartridge for use with a vaporizer device
USD842536S1 (en) 2016-07-28 2019-03-05 Juul Labs, Inc. Vaporizer cartridge
CN115281387A (zh) 2013-12-23 2022-11-04 尤尔实验室有限公司 蒸发装置***和方法
US20160366947A1 (en) 2013-12-23 2016-12-22 James Monsees Vaporizer apparatus
US10058129B2 (en) 2013-12-23 2018-08-28 Juul Labs, Inc. Vaporization device systems and methods
US10307464B2 (en) 2014-03-28 2019-06-04 Mannkind Corporation Use of ultrarapid acting insulin
EP3137140B1 (en) 2014-05-02 2019-07-10 Manta Devices, LLC Delivery device
CA3219298A1 (en) * 2014-06-30 2016-01-07 Syqe Medical Ltd. Drug dose cartridge for an inhaler device
MX2017000057A (es) 2014-06-30 2017-06-30 Syqe Medical Ltd Procedimiento y dispositivo para vaporizacion e inhalacion de sustancias aisladas.
PL3539599T3 (pl) 2014-06-30 2022-02-21 Syqe Medical Ltd. Wkład z dawką leku dla urządzenia inhalatora
AU2015283594B2 (en) 2014-06-30 2019-07-25 Syqe Medical Ltd. Flow regulating inhaler device
US11298477B2 (en) 2014-06-30 2022-04-12 Syqe Medical Ltd. Methods, devices and systems for pulmonary delivery of active agents
CA160775S (en) 2014-08-11 2015-09-29 Ploom Inc Electronic vaporization device with cartridge
US10561806B2 (en) 2014-10-02 2020-02-18 Mannkind Corporation Mouthpiece cover for an inhaler
EP3283150B1 (en) * 2015-04-15 2021-09-29 Philip Morris Products S.A. Dual resistance dry powder inhaler
US20170028111A1 (en) * 2015-07-29 2017-02-02 Innovative Therapies, Inc. Wound therapy device pressure monitoring and control system
JP6957454B2 (ja) * 2015-11-06 2021-11-02 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング ネブライザと容器とを有するシステム
RU2710563C2 (ru) * 2015-12-04 2019-12-27 Медспрай Бв Распылитель для жидкости
WO2017093966A1 (en) * 2015-12-04 2017-06-08 Trudell Medical International Huff cough simulation device
RS61567B1 (sr) * 2015-12-18 2021-04-29 Jt Int Sa Personalni isparivač
WO2017112748A1 (en) * 2015-12-21 2017-06-29 3M Innovative Properties Company Flow govenors for use in medicinal inhalers
EP3393563B1 (en) * 2015-12-21 2021-06-09 Kindeva Drug Delivery L.P. Flow governor assemblies for use in medicinal inhalers
US11806331B2 (en) 2016-01-06 2023-11-07 Syqe Medical Ltd. Low dose therapeutic treatment
USD861975S1 (en) 2016-02-08 2019-10-01 Juul Labs, Inc. Vaporizer device with cartridges
USD858869S1 (en) 2016-02-08 2019-09-03 Juul Labs, Inc. Vaporizer cartridge
BR112018016402B1 (pt) 2016-02-11 2023-12-19 Juul Labs, Inc Cartuchos de fixação segura para dispositivos vaporizadores
ES2966349T3 (es) 2016-05-19 2024-04-22 Trudell Medical Int Cámara de retención con válvula inteligente
USD849996S1 (en) 2016-06-16 2019-05-28 Pax Labs, Inc. Vaporizer cartridge
USD851830S1 (en) 2016-06-23 2019-06-18 Pax Labs, Inc. Combined vaporizer tamp and pick tool
USD836541S1 (en) 2016-06-23 2018-12-25 Pax Labs, Inc. Charging device
US10881818B2 (en) 2016-07-08 2021-01-05 Trudell Medical International Smart oscillating positive expiratory pressure device
US10786638B2 (en) 2016-07-08 2020-09-29 Trudell Medical International Nebulizer apparatus and method
GB201615603D0 (en) * 2016-09-14 2016-10-26 British American Tobacco Investments Ltd Receptacle section
GB201615602D0 (en) * 2016-09-14 2016-10-26 British American Tobacco Investments Ltd Receptacle Section
GB201615601D0 (en) * 2016-09-14 2016-10-26 British American Tobacco Investments Ltd Receptacle section
US11426539B2 (en) * 2016-12-06 2022-08-30 Heath Rainbow Inhaler housing
CA3036631A1 (en) 2016-12-09 2018-06-14 Trudell Medical International Smart nebulizer
GB201700136D0 (en) 2017-01-05 2017-02-22 British American Tobacco Investments Ltd Aerosol generating device and article
GB201700620D0 (en) 2017-01-13 2017-03-01 British American Tobacco Investments Ltd Aerosol generating device and article
JP7210476B2 (ja) 2017-05-22 2023-01-23 インスメッド インコーポレイテッド リポ‐グリコペプチド可切断性誘導体及びその使用
USD887632S1 (en) 2017-09-14 2020-06-16 Pax Labs, Inc. Vaporizer cartridge
GB201720338D0 (en) 2017-12-06 2018-01-17 British American Tobacco Investments Ltd Component for an aerosol-generating apparatus
AU2019205865A1 (en) 2018-01-04 2020-07-16 Trudell Medical International Inc. Smart oscillating positive expiratory pressure device
CN109224216B (zh) * 2018-10-23 2021-04-13 济南市儿童医院 用于呼吸***的理疗仪
GB2591064B (en) * 2018-11-29 2021-12-22 Kapitex Healthcare Ltd An improved speaking valve
GB2579364B (en) * 2018-11-29 2021-08-18 Kapitex Healthcare Ltd An improved speaking valve
MX2021006339A (es) * 2018-12-07 2021-08-11 Philip Morris Products Sa Cartucho y sistema generador de aerosol con proteccion contra fugas.
USD903192S1 (en) 2019-02-21 2020-11-24 Juul Labs, Inc. Vaporizer accessory
CN110338465A (zh) * 2019-07-16 2019-10-18 深圳麦克韦尔科技有限公司 换气阀及电子雾化装置
US11712175B2 (en) 2019-08-27 2023-08-01 Trudell Medical International Smart oscillating positive expiratory pressure device with feedback indicia
USD943159S1 (en) 2019-11-14 2022-02-08 Juul Labs, Inc. Component for a vaporizer cartridge
USD943158S1 (en) 2019-11-14 2022-02-08 Juul Labs, Inc. Vaporizer cartridge
USD943161S1 (en) 2019-11-14 2022-02-08 Juul Labs, Inc. Vaporizer device
USD943160S1 (en) 2019-11-14 2022-02-08 Juul Labs, Inc. Vaporizer device
USD917093S1 (en) * 2020-01-15 2021-04-20 2334271 Ontario Ltd. Capsule for use in a vaporizer device
FR3115996A1 (fr) * 2020-11-06 2022-05-13 Nemera La Verpilliere Système d’assistance à la distribution de produit
WO2023001685A1 (en) * 2021-07-21 2023-01-26 Jt International Sa Vapour generating device

Family Cites Families (139)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2587215A (en) 1949-04-27 1952-02-26 Frank P Priestly Inhalator
US3788310A (en) 1970-03-25 1974-01-29 Westinghouse Electric Corp Flow control apparatus
NO134730L (no) * 1971-07-19 1900-01-01
GB1392945A (en) 1972-08-23 1975-05-07 Fisons Ltd Inhalation device
US4086918A (en) 1976-02-11 1978-05-02 Chesebrough-Pond's Inc. Inhalation device
US4170228A (en) 1976-11-05 1979-10-09 C. R. Bard, Inc. Variable flow incentive spirometer
US4106503A (en) 1977-03-11 1978-08-15 Richard R. Rosenthal Metering system for stimulating bronchial spasm
GB1598053A (en) 1978-01-31 1981-09-16 Fisons Ltd Pocket inhaler
US4176617A (en) * 1978-03-23 1979-12-04 Pilipski M Low pressure alarm
US4274404A (en) 1979-04-13 1981-06-23 American Safety Flight Systems, Inc. Oxygen supply system controlled by user exhalation
IT1116047B (it) 1979-04-27 1986-02-10 Sigma Tau Ind Farmaceuti Dispositivo per la rapida inalazione di farmaci in polvere da parte di persone sofferenti di asma
US4284083A (en) 1979-05-29 1981-08-18 Lester Victor E Inhalation incentive device
US4259951A (en) 1979-07-30 1981-04-07 Chesebrough-Pond's Inc. Dual valve for respiratory device
DE3023648A1 (de) 1980-06-24 1982-01-21 Jaeger, Erich, 8700 Würzburg Einrichtung zur untersuchung der atemwege auf reizstoff-ueberempfindlichkeit
US4391283A (en) 1981-03-24 1983-07-05 Whitman Medical Corporation Incentive spirometer
US4484577A (en) 1981-07-23 1984-11-27 Key Pharmaceuticals, Inc. Drug delivery method and inhalation device therefor
US4442856A (en) 1981-08-18 1984-04-17 Puritan-Bennett Oxygen regulator and alarm system for an anesthesia machine
US4533137A (en) 1982-01-19 1985-08-06 Healthscan Inc. Pulmonary training method
US4444202A (en) 1982-03-31 1984-04-24 Howard Rubin Breathing exerciser
AU570013B2 (en) 1982-10-08 1988-03-03 Glaxo Group Limited Medicament inhaler
US4778054A (en) 1982-10-08 1988-10-18 Glaxo Group Limited Pack for administering medicaments to patients
US4495944A (en) 1983-02-07 1985-01-29 Trutek Research, Inc. Inhalation therapy apparatus
US4534343A (en) * 1984-01-27 1985-08-13 Trutek Research, Inc. Metered dose inhaler
NZ209900A (en) 1984-10-16 1989-08-29 Univ Auckland Automatic inhaler
US4592348A (en) 1984-12-17 1986-06-03 Waters Iv William C Aerosol inhaler
CA1272917A (en) 1985-07-30 1990-08-21 Paul Kenneth Rand Devices for administering medicaments to patients
SE453566B (sv) 1986-03-07 1988-02-15 Draco Ab Anordning vid pulverinhalatorer
US4926852B1 (en) 1986-06-23 1995-05-23 Univ Johns Hopkins Medication delivery system phase one
ES2051371T3 (es) 1988-10-04 1994-06-16 Univ Johns Hopkins Inhalador de aerosoles.
US5033655A (en) 1989-02-15 1991-07-23 Liquid Molding Systems Inc. Dispensing package for fluid products and the like
US4991745A (en) 1989-04-25 1991-02-12 Liquid Molding Systems, Inc. Dispensing valve with trampoline-like construction
ATE138814T1 (de) 1989-04-28 1996-06-15 Riker Laboratories Inc Inhalationsvorrichtung für trockenpulver
US4955371A (en) 1989-05-08 1990-09-11 Transtech Scientific, Inc. Disposable inhalation activated, aerosol device for pulmonary medicine
GB8919131D0 (en) 1989-08-23 1989-10-04 Riker Laboratories Inc Inhaler
US5201308A (en) 1990-02-14 1993-04-13 Newhouse Michael T Powder inhaler
SG45171A1 (en) * 1990-03-21 1998-01-16 Boehringer Ingelheim Int Atomising devices and methods
US5042467A (en) * 1990-03-28 1991-08-27 Trudell Medical Medication inhaler with fitting having a sonic signalling device
DE4027391A1 (de) 1990-08-30 1992-03-12 Boehringer Ingelheim Kg Treibgasfreies inhalationsgeraet
EP0546009B1 (en) * 1990-08-31 1995-03-29 Minnesota Mining And Manufacturing Company Aerosol actuator providing increased respirable fraction
DE4029183A1 (de) 1990-09-14 1992-03-19 Dieter Kuhn Durchflussregler
GB9021433D0 (en) 1990-10-02 1990-11-14 Atomic Energy Authority Uk Power inhaler
FR2667509B1 (fr) 1990-10-04 1995-08-25 Valois Inhalateur a poudre, dispositif de conditionnement de microdoses de poudre sous forme de bandes adaptees a etre utilisees dans un inhalateur a poudre, et procede de fabrication de ces bandes.
US5042472A (en) 1990-10-15 1991-08-27 Merck & Co., Inc. Powder inhaler device
GB9024760D0 (en) 1990-11-14 1991-01-02 Riker Laboratories Inc Inhalation device and medicament carrier
GB9026025D0 (en) 1990-11-29 1991-01-16 Boehringer Ingelheim Kg Inhalation device
GB9026191D0 (en) 1990-12-01 1991-01-16 Harris Pharma Ltd Breath actuated dispensing device
US5040527A (en) 1990-12-18 1991-08-20 Healthscan Products Inc. Metered dose inhalation unit with slide means
US5186164A (en) * 1991-03-15 1993-02-16 Puthalath Raghuprasad Mist inhaler
AU651882B2 (en) 1991-05-14 1994-08-04 Visiomed Group Limited Aerosol inhalation device
US6055980A (en) 1991-05-20 2000-05-02 Dura Pharmaceuticals, Inc. Dry powder inhaler
ES2284226T3 (es) 1991-07-02 2007-11-01 Nektar Therapeutics Dispositivo para proporcionar medicamentos en aerosol.
US5337740A (en) 1991-08-01 1994-08-16 New England Pharmaceuticals, Inc. Inhalation devices
US5161524A (en) 1991-08-02 1992-11-10 Glaxo Inc. Dosage inhalator with air flow velocity regulating means
US6029661A (en) 1991-08-26 2000-02-29 3M Innovative Properties Company Powder dispenser
EP0601071B1 (en) * 1991-08-26 1999-10-20 Minnesota Mining And Manufacturing Company Powder dispenser
US5167506A (en) 1991-10-24 1992-12-01 Minnesota Mining And Manufacturing Company Inhalation device training system
US5409144A (en) 1991-12-06 1995-04-25 Liquid Molding Systems Inc. Dispensing valve for packaging
US5213236A (en) 1991-12-06 1993-05-25 Liquid Molding Systems, Inc. Dispensing valve for packaging
DE4211475A1 (de) 1991-12-14 1993-06-17 Asta Medica Ag Pulverinhalator
US5320094A (en) 1992-01-10 1994-06-14 The Johns Hopkins University Method of administering insulin
EP0558879B1 (en) 1992-03-04 1997-05-14 Astra Aktiebolag Disposable inhaler
US5639441A (en) 1992-03-06 1997-06-17 Board Of Regents Of University Of Colorado Methods for fine particle formation
US5785049A (en) 1994-09-21 1998-07-28 Inhale Therapeutic Systems Method and apparatus for dispersion of dry powder medicaments
US5284133A (en) 1992-07-23 1994-02-08 Armstrong Pharmaceuticals, Inc. Inhalation device with a dose-timer, an actuator mechanism, and patient compliance monitoring means
US5333106A (en) 1992-10-09 1994-07-26 Circadian, Inc. Apparatus and visual display method for training in the power use of aerosol pharmaceutical inhalers
DE4239402A1 (de) 1992-11-24 1994-05-26 Bayer Ag Pulverinhalator
US5364838A (en) 1993-01-29 1994-11-15 Miris Medical Corporation Method of administration of insulin
US5558085A (en) 1993-01-29 1996-09-24 Aradigm Corporation Intrapulmonary delivery of peptide drugs
EP0681491B1 (en) 1993-01-29 2000-12-13 Aradigm Corporation Intrapulmonary delivery of hormones
US5888477A (en) 1993-01-29 1999-03-30 Aradigm Corporation Use of monomeric insulin as a means for improving the bioavailability of inhaled insulin
US5743250A (en) 1993-01-29 1998-04-28 Aradigm Corporation Insulin delivery enhanced by coached breathing
US5672581A (en) 1993-01-29 1997-09-30 Aradigm Corporation Method of administration of insulin
US5873358A (en) 1993-01-29 1999-02-23 Aradigm Corporation Method of maintaining a diabetic patient's blood glucose level in a desired range
US6012450A (en) * 1993-01-29 2000-01-11 Aradigm Corporation Intrapulmonary delivery of hematopoietic drug
FR2701399B1 (fr) 1993-02-16 1995-03-31 Valois Dispositif portatif de pulvérisation à actionnement déclenché par l'inhalation.
WO1994023772A2 (en) 1993-04-06 1994-10-27 Minnesota Mining And Manufacturing Company Deagglomerators for dry powder inhalers
US5497763A (en) * 1993-05-21 1996-03-12 Aradigm Corporation Disposable package for intrapulmonary delivery of aerosolized formulations
US5533502A (en) * 1993-05-28 1996-07-09 Vortran Medical Technology, Inc. Powder inhaler with aerosolization occurring within each individual powder receptacle
DK0714314T3 (da) 1993-08-18 1999-06-23 Fisons Plc Inhalator med åndedrætsregulering
US5655520A (en) 1993-08-23 1997-08-12 Howe; Harvey James Flexible valve for administering constant flow rates of medicine from a nebulizer
US6062219A (en) * 1993-11-09 2000-05-16 Cprx Llc Apparatus and methods for assisting cardiopulmonary resuscitation
US5692498A (en) * 1993-11-09 1997-12-02 Cprx, Inc. CPR device having valve for increasing the duration and magnitude of negative intrathoracic pressures
ATE192341T1 (de) 1993-12-18 2000-05-15 Merck Patent Gmbh Pulverinhalator
GB9326574D0 (en) 1993-12-31 1994-03-02 King S College London Dry power inhalers
US6102036A (en) 1994-04-12 2000-08-15 Smoke-Stop Breath activated inhaler
US5483954A (en) 1994-06-10 1996-01-16 Mecikalski; Mark B. Inhaler and medicated package
US5509404A (en) 1994-07-11 1996-04-23 Aradigm Corporation Intrapulmonary drug delivery within therapeutically relevant inspiratory flow/volume values
US5653223A (en) * 1994-09-08 1997-08-05 Pruitt; Michael D. Accurately controlled portable nebulizer
ES2302332T3 (es) 1994-09-21 2008-07-01 Nektar Therapeutics Aparato y metodos para dispersar medicamentos en polvo seco.
US5993421A (en) 1994-12-02 1999-11-30 Science Incorporated Medicament dispenser
SE9404439D0 (sv) 1994-12-21 1994-12-21 Astra Ab Inhalation device
US5522380A (en) * 1995-01-18 1996-06-04 Dwork; Paul Metered dose medication adaptor with improved incentive spirometer
ES2145421T3 (es) 1995-01-23 2000-07-01 Direct Haler A S Inhalador.
US5901703A (en) * 1995-02-06 1999-05-11 Unisia Jecs Corporation Medicine administering device for nasal cavities
US5513630A (en) 1995-03-08 1996-05-07 Century; Theodore J. Powder dispenser
US5586550A (en) 1995-08-31 1996-12-24 Fluid Propulsion Technologies, Inc. Apparatus and methods for the delivery of therapeutic liquids to the respiratory system
US5921237A (en) 1995-04-24 1999-07-13 Dura Pharmaceuticals, Inc. Dry powder inhaler
US5622166A (en) * 1995-04-24 1997-04-22 Dura Pharmaceuticals, Inc. Dry powder inhaler delivery system
US5654007A (en) 1995-06-07 1997-08-05 Inhale Therapeutic Systems Methods and system for processing dispersible fine powders
US5826571A (en) 1995-06-08 1998-10-27 Innovative Devices, Llc Device for use with metered dose inhalers (MDIS)
GB9513218D0 (en) * 1995-06-29 1995-09-06 Fisons Plc Inhalation device and method
DE19523516C1 (de) * 1995-06-30 1996-10-31 Asta Medica Ag Inhalator zum Verabreichen von Medikamenten aus Blisterpackungen
US5692496A (en) 1995-08-02 1997-12-02 Innovative Devices, Llc Dry powder medicament inhalator having an inhalation-activated flow diverting means for triggering delivery of medicament
US5988163A (en) 1995-08-02 1999-11-23 Innovative Devices Dry powder medicament inhalator having an inhalation-activated flow diverting means for triggering delivery of delivery of medicament
US5823183A (en) 1995-08-02 1998-10-20 Innovative Devices Dry powder medicament inhalator having an inhalation-activated flow diverting means for triggering delivery of medicament
US6209538B1 (en) * 1995-08-02 2001-04-03 Robert A. Casper Dry powder medicament inhalator having an inhalation-activated flow diverting means for triggering delivery of medicament
FR2738152B1 (fr) * 1995-09-04 1998-01-23 Tebro Dispositif de pre-dosage de produit pulverulent pour un distributeur de produit
US5738087A (en) * 1995-09-21 1998-04-14 King; Russell W. Aerosol medication delivery system
CN1213974A (zh) * 1996-01-03 1999-04-14 葛兰素集团有限公司 吸入器具
US6026809A (en) * 1996-01-25 2000-02-22 Microdose Technologies, Inc. Inhalation device
US5694920A (en) * 1996-01-25 1997-12-09 Abrams; Andrew L. Inhalation device
US5699789A (en) 1996-03-11 1997-12-23 Hendricks; Mark R. Dry powder inhaler
JP3328132B2 (ja) * 1996-03-21 2002-09-24 株式会社ユニシアジェックス 吸入式投薬器
DE19613185A1 (de) 1996-04-02 1997-10-09 Pfeiffer Erich Gmbh & Co Kg Dosiereinrichtung für strömungsfähige Medien wie Pulver/Luft-Dispersionen
US5875776A (en) 1996-04-09 1999-03-02 Vivorx Pharmaceuticals, Inc. Dry powder inhaler
US5826633A (en) 1996-04-26 1998-10-27 Inhale Therapeutic Systems Powder filling systems, apparatus and methods
GB2312848B (en) 1996-04-26 1999-11-17 Bespak Plc Controlled flow inhalers
ATE247948T1 (de) 1996-04-29 2003-09-15 Dura Pharma Inc Verfahren zum inhalieren trockener pulver
US5706830A (en) * 1996-05-06 1998-01-13 South Alabama Medical Science Foundation Liquid ventilator system and use thereof
US5813401A (en) 1996-10-15 1998-09-29 Radcliff; Janet H. Nebulizer automatic control valve
US5906202A (en) * 1996-11-21 1999-05-25 Aradigm Corporation Device and method for directing aerosolized mist to a specific area of the respiratory tract
SE9700422D0 (sv) 1997-02-07 1997-02-07 Astra Ab Single dose inhaler II
US6006747A (en) 1997-03-20 1999-12-28 Dura Pharmaceuticals, Inc. Dry powder inhaler
DE19734022C2 (de) * 1997-08-06 2000-06-21 Pari Gmbh Inhalationstherapiegerät mit einem Ventil zur Begrenzung des Inspirationsflusses
CA2212430A1 (en) 1997-08-07 1999-02-07 George Volgyesi Inhalation device
US6044841A (en) * 1997-08-29 2000-04-04 1263152 Ontario Inc. Breath actuated nebulizer with valve assembly having a relief piston
US5855202A (en) 1997-10-08 1999-01-05 Andrade; Joseph R. Aerosol holding chamber for a metered-dose inhaler
US6116238A (en) * 1997-12-02 2000-09-12 Dura Pharmaceuticals, Inc. Dry powder inhaler
US6237591B1 (en) * 1998-11-02 2001-05-29 Dura Pharmaceuticals, Inc. Turbine dry powder inhaler
US6076523A (en) 1998-01-15 2000-06-20 Nellcor Puritan Bennett Oxygen blending in a piston ventilator
CN1106888C (zh) * 1998-03-10 2003-04-30 瓦卢瓦股份有限公司 容器、容器的灌注方法及容器中流体制品的分配装置
BR9908771A (pt) 1998-03-16 2000-12-12 Inhale Therapeutic Syst Processos para a liberação de um agente ativo e de insulina para os pulmões de um paciente humano, dispositivo para aumentar a biodisponibilidade de um agente ativo, e, dispositivos para a liberação de um agente ativo e de insulina para os pulmões de um paciente humano
US6142146A (en) 1998-06-12 2000-11-07 Microdose Technologies, Inc. Inhalation device
US6234169B1 (en) * 1998-08-14 2001-05-22 Arthur Slutsky Inhaler
UA73924C2 (en) 1998-10-09 2005-10-17 Nektar Therapeutics Device for delivering active agent formulation to lungs of human patient
US6223744B1 (en) * 1999-03-16 2001-05-01 Multi-Vet Ltd. Wearable aerosol delivery apparatus
US6527011B1 (en) * 2000-05-18 2003-03-04 Robert F. Mantz Flexible retainer ring for duck bill valve
US6408847B1 (en) * 2000-08-29 2002-06-25 Marshall L. Nuckols Rebreather system that supplies fresh make-up gas according to a user's respiratory minute volume
US8949406B2 (en) 2008-08-14 2015-02-03 International Business Machines Corporation Method and system for communication between a client system and a server system

Also Published As

Publication number Publication date
BG106218A (bg) 2002-07-31
AU771926B2 (en) 2004-04-08
IL147303A (en) 2010-02-17
TR200202521T2 (tr) 2003-02-21
LT2002008A (en) 2002-06-25
ES2347410T3 (es) 2010-10-29
EE200100714A (et) 2003-04-15
HU225182B1 (en) 2006-07-28
WO2001000263A3 (en) 2001-05-31
CO5280133A1 (es) 2003-05-30
CZ20014723A3 (cs) 2002-06-12
HUP0201726A2 (en) 2002-10-28
NO20016277D0 (no) 2001-12-20
HK1047408A1 (zh) 2003-02-21
CN1217713C (zh) 2005-09-07
KR100885713B1 (ko) 2009-02-26
KR20020016641A (ko) 2002-03-04
BR0012013A (pt) 2002-03-26
JP2006312086A (ja) 2006-11-16
AP2001002366A0 (en) 2001-12-31
TR200103800T2 (tr) 2002-06-21
JP4607834B2 (ja) 2011-01-05
EA003153B1 (ru) 2003-02-27
PE20010356A1 (es) 2001-03-18
NO20016277L (no) 2002-02-28
MY125534A (en) 2006-08-30
GEP20043258B (en) 2004-06-25
PA8497901A1 (es) 2002-10-31
MXPA01012789A (es) 2002-09-18
EA200101252A1 (ru) 2002-06-27
DE60044719D1 (de) 2010-09-02
HRP20010936A2 (en) 2005-06-30
IL147303A0 (en) 2002-08-14
LV12804A (en) 2002-03-20
ATE474615T1 (de) 2010-08-15
WO2001000263A9 (en) 2001-06-21
LV12804B (en) 2002-10-20
KR20080081376A (ko) 2008-09-09
PL205905B1 (pl) 2010-06-30
CA2377625A1 (en) 2001-01-04
TR200202522T2 (tr) 2003-02-21
TW470655B (en) 2002-01-01
RS50349B (sr) 2009-11-10
YU89801A (sh) 2004-07-15
TNSN00148A1 (fr) 2005-11-10
US20050016533A1 (en) 2005-01-27
LT4943B (lt) 2002-08-26
MA26800A1 (fr) 2004-12-20
SG135936A1 (en) 2007-10-29
JP2003503117A (ja) 2003-01-28
EP1212111B1 (en) 2010-07-21
PL352903A1 (en) 2003-09-22
AP1611A (en) 2006-05-17
AU5903500A (en) 2001-01-31
WO2001000263A2 (en) 2001-01-04
CN1365294A (zh) 2002-08-21
DZ3169A1 (fr) 2001-01-04
CA2377625C (en) 2010-08-10
EP1212111A1 (en) 2002-06-12
US6606992B1 (en) 2003-08-19
UY26232A1 (es) 2001-01-31
PT1212111E (pt) 2010-09-21
NZ516098A (en) 2004-04-30
WO2001000263A8 (en) 2002-07-25
IS6197A (is) 2001-12-13
EE04631B1 (et) 2006-06-15

Similar Documents

Publication Publication Date Title
HK1047714A1 (en) Systems and methods for aerosolizing pharmaceutical formulations
IL147756A0 (en) Preserved pharmaceutical formulations
IL139087A0 (en) Pharmaceutical aerosol formulation
AU5326100A (en) Pharmaceutical compositions and methods for use
AU6715600A (en) Pharmaceutical formulations
EP1173216A4 (en) PHARMACEUTICAL FORMULATIONS
GB9924992D0 (en) Pharmaceutical aerosol formulations
GB9909154D0 (en) Pharmaceutical formulation
IL136635A0 (en) Pharmaceutical formulations and processes for their preparation
GB9930578D0 (en) Pharmaceutical formulations
GB9906126D0 (en) Pharmaceutical formulations
GB9926251D0 (en) Pharmaceutical formulation
EG22710A (en) Systems and methods for aerosolizing pharmaceutical formulations
ZA200110214B (en) Systems and methods for aerosolizing pharmaceutical formulations.
GB9905983D0 (en) Pharmaceutical formulations
GB9911826D0 (en) Pharmaceutical formulations
GB9903177D0 (en) Pharmaceutical formulations
GB9921289D0 (en) Pharmaceutical aerosol formulation
SI1124539T1 (en) Pharmaceutical formulation comprising omeprazole
GB9921396D0 (en) Pharmaceutical formulation
GB9927685D0 (en) Pharmaceutical formulation
GB9917777D0 (en) Pharmaceutical formulation
GB9917775D0 (en) Pharmaceutical formulation
GB9917774D0 (en) Pharmaceutical formulation
GB9917772D0 (en) Pharmaceutical formulation

Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20100629