HK1046648B - 包括最少兩個不同變應原蛋白的含雜種多肽疫苗 - Google Patents
包括最少兩個不同變應原蛋白的含雜種多肽疫苗Info
- Publication number
- HK1046648B HK1046648B HK02108362.1A HK02108362A HK1046648B HK 1046648 B HK1046648 B HK 1046648B HK 02108362 A HK02108362 A HK 02108362A HK 1046648 B HK1046648 B HK 1046648B
- Authority
- HK
- Hong Kong
- Prior art keywords
- hybrid polypeptides
- allergenic proteins
- vaccines containing
- polypeptides consisting
- containing hybrid
- Prior art date
Links
- 230000002009 allergenic effect Effects 0.000 title abstract 3
- 229920001184 polypeptide Polymers 0.000 title abstract 3
- 102000004196 processed proteins & peptides Human genes 0.000 title abstract 3
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 3
- 102000004169 proteins and genes Human genes 0.000 title abstract 3
- 108090000623 proteins and genes Proteins 0.000 title abstract 3
- 229960005486 vaccine Drugs 0.000 title abstract 2
- 239000012634 fragment Substances 0.000 abstract 2
- 150000001413 amino acids Chemical class 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 102000040430 polynucleotide Human genes 0.000 abstract 1
- 108091033319 polynucleotide Proteins 0.000 abstract 1
- 239000002157 polynucleotide Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/415—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from plants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/62—DNA sequences coding for fusion proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/53—DNA (RNA) vaccination
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/20—Fusion polypeptide containing a tag with affinity for a non-protein ligand
- C07K2319/21—Fusion polypeptide containing a tag with affinity for a non-protein ligand containing a His-tag
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/40—Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Zoology (AREA)
- Biophysics (AREA)
- Biotechnology (AREA)
- Medicinal Chemistry (AREA)
- General Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Biochemistry (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Physics & Mathematics (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Plant Pathology (AREA)
- Microbiology (AREA)
- Public Health (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Botany (AREA)
- Gastroenterology & Hepatology (AREA)
- Pulmonology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP00128660A EP1221317A1 (en) | 2000-12-28 | 2000-12-28 | Vaccines containing hybrid polypeptides consisting of at least two different allergenic proteins |
Publications (2)
Publication Number | Publication Date |
---|---|
HK1046648A1 HK1046648A1 (en) | 2003-01-24 |
HK1046648B true HK1046648B (zh) | 2007-10-26 |
Family
ID=8170854
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK02108362.1A HK1046648B (zh) | 2000-12-28 | 2002-11-19 | 包括最少兩個不同變應原蛋白的含雜種多肽疫苗 |
Country Status (8)
Country | Link |
---|---|
US (2) | US7862828B2 (zh) |
EP (2) | EP1221317A1 (zh) |
AT (1) | ATE367826T1 (zh) |
DE (1) | DE60129528T2 (zh) |
DK (1) | DK1219301T3 (zh) |
ES (1) | ES2287067T3 (zh) |
HK (1) | HK1046648B (zh) |
PT (1) | PT1219301E (zh) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE60301944T2 (de) | 2003-01-21 | 2006-06-01 | Biomay Produktions- Und Handels-Aktiengesellschaft | Verfahren zur Vorbereitung von hypoallergenen Mosaikproteinen# |
US8709435B2 (en) | 2003-01-21 | 2014-04-29 | Biomay Ag | Hypallergenic mosaic antigens and methods of making same |
ITRM20030247A1 (it) * | 2003-05-20 | 2004-11-21 | Bonura Angela | Varianti ipoallergeniche degli allergeni maggiori |
US20070122417A1 (en) * | 2003-09-30 | 2007-05-31 | Patrick Holt | Immunotherapy method |
DE10351471A1 (de) * | 2003-11-04 | 2005-06-09 | Ursula Prof. Dr. Wiedermann-Schmidt | Polyvalente Allergievakzine |
DK1868642T3 (da) * | 2005-03-18 | 2013-06-24 | Cytos Biotechnology Ag | Katte-allergenfusionsproteiner og anvendelser deraf |
US20070065468A1 (en) * | 2005-08-29 | 2007-03-22 | National University Of Singapore | Chimeric allergens for immunotherapy |
ES2307381B1 (es) * | 2006-04-12 | 2009-10-23 | Bial Industrial Farmaceutica S.A. | Proteinas quimericas hipoalergenicas pertenecientes a la familia de transportadoras de lipidos de parietaria judaica utiles para el tratami ento de alergias. |
AT503690A1 (de) * | 2006-06-09 | 2007-12-15 | Biomay Ag | Hypoallergene moleküle |
MX2010010353A (es) | 2008-03-25 | 2010-10-05 | Bial Ind Farmaceutica S A | Proteinas hibridas hipoalergenicas de los alergenos mayoritarios de acaros pertenecientes a los grupos 1 y 2 utiles para su utilizacion en el tratamiento de alergias. |
EP2295076A1 (en) | 2009-09-10 | 2011-03-16 | Biomay Ag | Hypoallergenic hybrid polypeptides for the treatment of allergy |
ITMI20112301A1 (it) * | 2011-12-19 | 2013-06-20 | Lofarma Spa | Varianti ipoallergeniche dell'allergene maggiore phl p 5 di phleum pratense |
US9163069B2 (en) | 2012-09-20 | 2015-10-20 | Universidad De Cartagena | Fusion proteins representing different allergens and a vaccine against allergy to mites |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5116612A (en) * | 1987-06-23 | 1992-05-26 | Allergy Immuno Technologies, Inc. | Immunotherapy agents for treatment of IgE mediated allergies |
JP2596466B2 (ja) * | 1990-03-03 | 1997-04-02 | アサヒビール株式会社 | ダニの主要アレルゲンの還伝情報を有するdnaおよび該アレルゲンの製造方法 |
US5736362A (en) * | 1990-10-26 | 1998-04-07 | The University Of Melbourne | Ryegrass pollen allergen |
NZ299122A (en) | 1991-10-16 | 2005-02-25 | Immulogic Pharma Corp | Detecting and treating allergies using peptides with T-cell stimulating activity |
US5968526A (en) * | 1994-04-14 | 1999-10-19 | Immulogic Pharamaceutical Corporation | T cell epitopes of the major allergens from Dermatophagoides (house dust mite) |
SE9402089D0 (sv) * | 1994-06-14 | 1994-06-14 | Rudolf Valenta | Recombinant allergen, fragments thereof, corresponding recombinant DNA molecules, vectors and hosts containing the DNA molecules, diagnostic and therapeutic uses of said allergens and fragments |
GB9516293D0 (en) | 1995-08-09 | 1995-10-11 | Immunova Ltee | Novel peptides and their use as vaccines |
GB9516760D0 (en) * | 1995-08-16 | 1995-10-18 | Sandoz Ltd | Organic compounds |
US5804201A (en) * | 1996-03-11 | 1998-09-08 | The Rockefeller University | Immunomodulatory peptides of vespid antigen 5 |
-
2000
- 2000-12-28 EP EP00128660A patent/EP1221317A1/en not_active Withdrawn
-
2001
- 2001-12-20 AT AT01130292T patent/ATE367826T1/de not_active IP Right Cessation
- 2001-12-20 DK DK01130292T patent/DK1219301T3/da active
- 2001-12-20 ES ES01130292T patent/ES2287067T3/es not_active Expired - Lifetime
- 2001-12-20 EP EP01130292A patent/EP1219301B1/en not_active Expired - Lifetime
- 2001-12-20 PT PT01130292T patent/PT1219301E/pt unknown
- 2001-12-20 DE DE60129528T patent/DE60129528T2/de not_active Expired - Lifetime
- 2001-12-27 US US10/026,914 patent/US7862828B2/en not_active Expired - Fee Related
-
2002
- 2002-11-19 HK HK02108362.1A patent/HK1046648B/zh not_active IP Right Cessation
-
2010
- 2010-11-26 US US12/954,821 patent/US20110150920A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
US20020173625A1 (en) | 2002-11-21 |
ATE367826T1 (de) | 2007-08-15 |
DE60129528D1 (de) | 2007-09-06 |
US7862828B2 (en) | 2011-01-04 |
EP1219301A1 (en) | 2002-07-03 |
EP1221317A1 (en) | 2002-07-10 |
PT1219301E (pt) | 2007-09-04 |
DE60129528T2 (de) | 2008-04-10 |
HK1046648A1 (en) | 2003-01-24 |
US20110150920A1 (en) | 2011-06-23 |
EP1219301B1 (en) | 2007-07-25 |
DK1219301T3 (da) | 2007-10-22 |
ES2287067T3 (es) | 2007-12-16 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PC | Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee) |
Effective date: 20111220 |