HK1041480A1 - Quinoline derivatives - Google Patents

Quinoline derivatives

Info

Publication number
HK1041480A1
HK1041480A1 HK02101212.8A HK02101212A HK1041480A1 HK 1041480 A1 HK1041480 A1 HK 1041480A1 HK 02101212 A HK02101212 A HK 02101212A HK 1041480 A1 HK1041480 A1 HK 1041480A1
Authority
HK
Hong Kong
Prior art keywords
quinoline derivatives
quinoline
derivatives
Prior art date
Application number
HK02101212.8A
Other languages
Chinese (zh)
Inventor
Mary Gaster Laramie
Daniel Heightman Tom
Original Assignee
Smithkline Beecham Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Plc filed Critical Smithkline Beecham Plc
Publication of HK1041480A1 publication Critical patent/HK1041480A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/14—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/22—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed systems contains four or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
HK02101212.8A 1998-12-17 2002-02-19 Quinoline derivatives HK1041480A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9827882.3A GB9827882D0 (en) 1998-12-17 1998-12-17 Novel compounds
PCT/EP1999/009564 WO2000035919A2 (en) 1998-12-17 1999-12-03 Quinoline derivatives

Publications (1)

Publication Number Publication Date
HK1041480A1 true HK1041480A1 (en) 2002-07-12

Family

ID=10844468

Family Applications (1)

Application Number Title Priority Date Filing Date
HK02101212.8A HK1041480A1 (en) 1998-12-17 2002-02-19 Quinoline derivatives

Country Status (17)

Country Link
EP (1) EP1140946A2 (en)
JP (1) JP2002532501A (en)
KR (1) KR20010108028A (en)
CN (1) CN1335850A (en)
AU (1) AU3036000A (en)
BR (1) BR9916307A (en)
CA (1) CA2355234A1 (en)
CO (1) CO5150146A1 (en)
CZ (1) CZ20012151A3 (en)
GB (1) GB9827882D0 (en)
HK (1) HK1041480A1 (en)
HU (1) HUP0104662A2 (en)
IL (1) IL143782A0 (en)
NO (1) NO20013003L (en)
PL (1) PL353156A1 (en)
TR (1) TR200101764T2 (en)
WO (1) WO2000035919A2 (en)

Families Citing this family (60)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9926303D0 (en) * 1999-11-05 2000-01-12 Smithkline Beecham Plc Novel compounds
EP1844771A3 (en) * 2001-06-20 2007-11-07 Wyeth Substituted indole acid derivatives as inhibitors of plasminogen activator inhibitor-1 (PAI-1)
TWI224101B (en) 2001-06-20 2004-11-21 Wyeth Corp Substituted naphthyl indole derivatives as inhibitors of plasminogen activator inhibitor type-1 (PAI-1)
DK1397130T3 (en) 2001-06-20 2007-11-12 Wyeth Corp Substituted Indole Acid Derivatives as Inhibitors of Plasminogen Activator Inhibitor-1 (PAI-1)
WO2003045313A2 (en) 2001-11-27 2003-06-05 Merck & Co. Inc. 2-aminoquinoline compounds
CN1723198A (en) 2002-12-10 2006-01-18 惠氏公司 Aryl, aryloxy, and alkyloxy substituted 1h-indol-3-yl glyoxylic acid derivatives as inhibitors of plasminogen activator inhibitor-1 (PAI-1)
EP1569899B1 (en) 2002-12-10 2006-06-28 Wyeth Substituted 3-alkyl- and 3-arylalkyl-1h-indol-1-yl-acetic acid derivatives as inhibitors of plasminogen activator inhibitor-1 (pai-1)
CN1726191A (en) 2002-12-10 2006-01-25 惠氏公司 Substituted indole oxo-acetyl amino acetic acid derivatives as inhibitors of plasminogen activator inhibitor-1 (PAI-1)
DK1569900T3 (en) 2002-12-10 2006-10-23 Wyeth Corp Substituted 3-carbonyl-1-yl acetic acid derivatives as inhibitors of plasminogen activator inhibitor-1 (PAI-1)
UA80453C2 (en) 2002-12-10 2007-09-25 Derivatives of substituted dyhydropyranoindol-3,4-dion as inhibitors of plasminogen activator inhibitor-1 (pai-1)
US7582773B2 (en) 2003-09-25 2009-09-01 Wyeth Substituted phenyl indoles
US7351726B2 (en) 2003-09-25 2008-04-01 Wyeth Substituted oxadiazolidinediones
US7268159B2 (en) 2003-09-25 2007-09-11 Wyeth Substituted indoles
US7446201B2 (en) 2003-09-25 2008-11-04 Wyeth Substituted heteroaryl benzofuran acids
US7332521B2 (en) 2003-09-25 2008-02-19 Wyeth Substituted indoles
US7141592B2 (en) 2003-09-25 2006-11-28 Wyeth Substituted oxadiazolidinediones
US7163954B2 (en) 2003-09-25 2007-01-16 Wyeth Substituted naphthyl benzothiophene acids
US7442805B2 (en) 2003-09-25 2008-10-28 Wyeth Substituted sulfonamide-indoles
US7265148B2 (en) 2003-09-25 2007-09-04 Wyeth Substituted pyrrole-indoles
BRPI0418102A (en) 2003-12-23 2007-04-27 Pfizer quinoline derivatives
UY30892A1 (en) 2007-02-07 2008-09-02 Smithkline Beckman Corp AKT ACTIVITY INHIBITORS
CN105360131A (en) 2010-11-03 2016-03-02 陶氏益农公司 Pesticidal Compositions and Processes Related Thereto
CA2852688C (en) 2011-10-26 2021-06-29 Dow Agrosciences Llc Pesticidal compositions and processes related thereto
BR112014026746A2 (en) 2012-04-27 2017-06-27 Dow Agrosciences Llc pesticide compositions and processes related thereto
US9708288B2 (en) 2012-04-27 2017-07-18 Dow Agrosciences Llc Pesticidal compositions and processes related thereto
US9282739B2 (en) 2012-04-27 2016-03-15 Dow Agrosciences Llc Pesticidal compositions and processes related thereto
US10092574B2 (en) 2012-09-26 2018-10-09 Valorisation-Recherche, Limited Partnership Inhibitors of polynucleotide repeat-associated RNA foci and uses thereof
US9102655B2 (en) 2013-10-17 2015-08-11 Dow Agrosciences Llc Processes for the preparation of pesticidal compounds
CN105636444B (en) 2013-10-17 2018-04-27 美国陶氏益农公司 The method for preparing Pesticidal compound
KR20160072154A (en) 2013-10-17 2016-06-22 다우 아그로사이언시즈 엘엘씨 Processes for the preparation of pesticidal compounds
MX2016004941A (en) 2013-10-17 2016-06-28 Dow Agrosciences Llc Processes for the preparation of pesticidal compounds.
CN105636440A (en) 2013-10-17 2016-06-01 美国陶氏益农公司 Processes for the preparation of pesticidal compounds
KR20160074542A (en) 2013-10-17 2016-06-28 다우 아그로사이언시즈 엘엘씨 Processes for the preparation of pesticidal compounds
US9174962B2 (en) 2013-10-17 2015-11-03 Dow Agrosciences Llc Processes for the preparation of pesticidal compounds
AU2014340443B2 (en) 2013-10-22 2017-06-08 Dow Agrosciences Llc Synergistic pesticidal compositions and related methods
JP2016538265A (en) 2013-10-22 2016-12-08 ダウ アグロサイエンシィズ エルエルシー Synergistic pest control compositions and related methods
NZ719688A (en) 2013-10-22 2017-06-30 Dow Agrosciences Llc Pesticidal compositions and related methods
US9549560B2 (en) 2013-10-22 2017-01-24 Dow Agrosciences Llc Pesticidal compositions and related methods
AR098097A1 (en) 2013-10-22 2016-05-04 Dow Agrosciences Llc SYNERGIC PESTICIATED COMPOSITIONS AND RELATED METHODS
RU2016119569A (en) 2013-10-22 2017-11-28 ДАУ АГРОСАЙЕНСИЗ ЭлЭлСи SYNERGETIC PESTICIDE COMPOSITIONS AND WAYS RELATED TO THEM
EP3062619B1 (en) 2013-10-22 2019-07-24 Dow AgroSciences LLC Pesticidal compositions and related methods
CN105848482A (en) 2013-10-22 2016-08-10 美国陶氏益农公司 Synergistic pesticidal compositions and related methods
MX2016005325A (en) 2013-10-22 2016-08-08 Dow Agrosciences Llc Synergistic pesticidal compositions and related methods.
KR20160074628A (en) 2013-10-22 2016-06-28 다우 아그로사이언시즈 엘엘씨 Synergistic pesticidal compositions and related methods
JP2016535025A (en) 2013-10-22 2016-11-10 ダウ アグロサイエンシィズ エルエルシー Synergistic pest control compositions and related methods
WO2015061163A1 (en) 2013-10-22 2015-04-30 Dow Agrosciences Llc Pesticidal compositions and related methods
MX2016005317A (en) 2013-10-22 2016-08-12 Dow Agrosciences Llc Pesticidal compositions and related methods.
CA2926647A1 (en) 2013-10-22 2015-04-30 Dow Agrosciences Llc Pesticidal compositions and related methods
AR098092A1 (en) 2013-10-22 2016-05-04 Dow Agrosciences Llc SYNERGIC PESTICIDE COMPOSITIONS AND RELATED METHODS
AR098088A1 (en) 2013-10-22 2016-05-04 Dow Agrosciences Llc SYNERGIC PESTICIATED COMPOSITIONS AND RELATED METHODS
KR20160074620A (en) 2013-10-22 2016-06-28 다우 아그로사이언시즈 엘엘씨 Synergistic pesticidal compositions and related methods
JP2017522306A (en) 2014-07-31 2017-08-10 ダウ アグロサイエンシィズ エルエルシー Method for producing 3- (3-chloro-1H-pyrazol-1-yl) pyridine
AR098110A1 (en) 2014-07-31 2016-05-04 Dow Agrosciences Llc PROCESS FOR THE PREPARATION OF 3- (3-CHLORINE-1H-PIRAZOL-1-IL) PIRIDINE
EP3174856A4 (en) 2014-07-31 2018-01-10 Dow AgroSciences LLC Process for the preparation of 3-(3-chloro-1h-pyrazol-1-yl)pyridine
KR20170042714A (en) 2014-08-19 2017-04-19 다우 아그로사이언시즈 엘엘씨 Process for the preparation of 3-(3-chloro-1h-pyrazol-1-yl)pyridine
CA2960985A1 (en) 2014-09-12 2016-03-17 Dow Agrosciences Llc Process for the preparation of 3-(3-chloro-1h-pyrazol-1-yl)pyridine
CN110325036B (en) 2016-12-29 2021-10-26 美国陶氏益农公司 Process for preparing pesticidal compounds
JP2020503336A (en) 2016-12-29 2020-01-30 ダウ アグロサイエンシィズ エルエルシー Method for preparing pesticidal compounds
CN108570450A (en) * 2017-03-11 2018-09-25 华中科技大学鄂州工业技术研究院 A kind of application of cell model and its construction and screening Serotonin receptor target active substance
CN106883192B (en) * 2017-03-30 2019-05-14 苏州汉德创宏生化科技有限公司 The synthetic method of the benzoic acid derivative of nitrogenous class heterocyclic antineoplastic pharmaceutical actives oxazolyl modification

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0716656A1 (en) * 1993-09-03 1996-06-19 Smithkline Beecham Plc Amide derivatives as 5ht1d receptor antagonists
WO1998047868A1 (en) * 1997-04-18 1998-10-29 Smithkline Beecham Plc Heterocycle-containing urea derivatives as 5ht1a, 5ht1b and 5ht1d receptor antagonists
WO1998050358A1 (en) * 1997-04-18 1998-11-12 Smithkline Beecham Plc Indole derivatives having combined 5ht1a, 5ht1b and 5ht1d receptor antagonist activity
JP2002508366A (en) * 1997-12-12 2002-03-19 スミスクライン・ビーチャム・パブリック・リミテッド・カンパニー Quinoline piperazine and quinoline piperidine derivatives, methods for their preparation, and their use as complex 5-HT1A, 5-HT1B and 5-HT1D receptor antagonists

Also Published As

Publication number Publication date
IL143782A0 (en) 2002-04-21
PL353156A1 (en) 2003-10-20
EP1140946A2 (en) 2001-10-10
HUP0104662A2 (en) 2002-04-29
WO2000035919A2 (en) 2000-06-22
WO2000035919A3 (en) 2000-10-26
TR200101764T2 (en) 2001-10-22
CN1335850A (en) 2002-02-13
NO20013003D0 (en) 2001-06-15
CZ20012151A3 (en) 2001-12-12
BR9916307A (en) 2002-01-15
CA2355234A1 (en) 2000-06-22
NO20013003L (en) 2001-07-25
GB9827882D0 (en) 1999-02-10
JP2002532501A (en) 2002-10-02
CO5150146A1 (en) 2002-04-29
AU3036000A (en) 2000-07-03
KR20010108028A (en) 2001-12-07

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