HK1029916A1 - Use of inosine for the manufacture of a medicamentfor stimulating axonal outgrowth of central nervous system neurons. - Google Patents

Use of inosine for the manufacture of a medicamentfor stimulating axonal outgrowth of central nervous system neurons.

Info

Publication number
HK1029916A1
HK1029916A1 HK00108201A HK00108201A HK1029916A1 HK 1029916 A1 HK1029916 A1 HK 1029916A1 HK 00108201 A HK00108201 A HK 00108201A HK 00108201 A HK00108201 A HK 00108201A HK 1029916 A1 HK1029916 A1 HK 1029916A1
Authority
HK
Hong Kong
Prior art keywords
inosine
nervous system
central nervous
medicamentfor
manufacture
Prior art date
Application number
HK00108201A
Other languages
English (en)
Inventor
Larry I Benowitz
Original Assignee
Childrens Medical Center
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Childrens Medical Center filed Critical Childrens Medical Center
Publication of HK1029916A1 publication Critical patent/HK1029916A1/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
    • A61K31/7076—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines containing purines, e.g. adenosine, adenylic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52—Purines, e.g. adenine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
    • A61K31/7076—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines containing purines, e.g. adenosine, adenylic acid
    • A61K31/708—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines containing purines, e.g. adenosine, adenylic acid having oxo groups directly attached to the purine ring system, e.g. guanosine, guanylic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Medicinal Preparation (AREA)
HK00108201A 1997-09-02 2000-12-19 Use of inosine for the manufacture of a medicamentfor stimulating axonal outgrowth of central nervous system neurons. HK1029916A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/921,902 US6440455B1 (en) 1997-09-02 1997-09-02 Methods for modulating the axonal outgrowth of central nervous system neurons
PCT/US1998/003001 WO1999011274A1 (en) 1997-09-02 1998-02-20 Use of purine nucleosides for modulating the axonal outgrowth of central nervous system neurons

Publications (1)

Publication Number Publication Date
HK1029916A1 true HK1029916A1 (en) 2001-04-20

Family

ID=25446158

Family Applications (1)

Application Number Title Priority Date Filing Date
HK00108201A HK1029916A1 (en) 1997-09-02 2000-12-19 Use of inosine for the manufacture of a medicamentfor stimulating axonal outgrowth of central nervous system neurons.

Country Status (13)

Country Link
US (8) US6440455B1 (de)
EP (2) EP1466606A3 (de)
JP (1) JP4601816B2 (de)
KR (1) KR100564789B1 (de)
CN (1) CN1286632A (de)
AT (1) ATE271874T1 (de)
AU (1) AU748961B2 (de)
CA (1) CA2302156C (de)
DE (1) DE69825292T2 (de)
HK (1) HK1029916A1 (de)
NZ (1) NZ503073A (de)
RU (1) RU2212241C2 (de)
WO (1) WO1999011274A1 (de)

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US7172871B1 (en) * 2000-09-07 2007-02-06 Children's Medical Center Corporation Methods and compositions for modulating axonal outgrowth of central nervous system neurons
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BRPI0714173A2 (pt) * 2006-07-12 2012-12-25 Elan Pharma Int Ltd composiÇço nanoparticulada estÁvel,mÉtodos para preparar a composiÇço, para prevenir e/ou tratar estados de doenÇas, sintomas, sÍndromes e condiÇÕes do sistema nervoso central, para melhorar ou manter a biodisponibilidade de modafinil, e para tratar distérbio com base neurolàgica, composiÇço farmacÊutica, e forma de dosagem
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EP2259677A4 (de) * 2008-02-29 2011-11-02 Alseres Pharmaceuticals Inc Systemische purinverabreichung zur modulation des axonalen wachstums des zentralnervensystems
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LT2807192T (lt) 2012-01-27 2018-07-25 AbbVie Deutschland GmbH & Co. KG Kompozicijos ir būdai, skirti ligų, susijusių su neuritų degeneracija, diagnostikai ir gydymui
US20140179741A1 (en) * 2012-10-10 2014-06-26 Massachusetts Institute Of Technology Use of chelators of divalent cations to promote nerve regeneration
WO2014096958A1 (en) * 2012-11-02 2014-06-26 Academisch Medisch Centrum Inosine monophosphate and salts thereof for use in the treatment of complement-related disorders
RU2517117C2 (ru) * 2012-11-26 2014-05-27 Государственное бюджетное образовательное учреждение высшего профессионального образования "Казанский государственный медицинский университет" Министерства здравоохранения и социального развития Российской Федерации (ГБОУ ВПО Казанский ГМУ Минздравсоцразвития России) Способ стимулирования регенерации нерва с помощью наноструктурированного матрикса и генетических конструкций
US10682372B2 (en) 2015-08-26 2020-06-16 Stagen Co., Ltd. Intracellular ATP enhancer
WO2020140730A1 (zh) * 2018-12-30 2020-07-09 广州君赫生物科技有限公司 硫鸟嘌呤在制备治疗adsl缺陷症药物中应用
EP3797764A1 (de) 2019-09-27 2021-03-31 Janusz Chupty Contissi Pharmakologische zusammensetzung zur behandlung von dysfunktion des nervengewebes, insbesondere der viralen latenz, und die verwendung von substanzen der gruppe j05 atc zur behandlung von dysfunktion des nervengewebes, insbesondere der viralen latenz
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Also Published As

Publication number Publication date
US20050277614A1 (en) 2005-12-15
AU6656898A (en) 1999-03-22
JP4601816B2 (ja) 2010-12-22
US20020042390A1 (en) 2002-04-11
EP1466606A2 (de) 2004-10-13
US20020137721A1 (en) 2002-09-26
ATE271874T1 (de) 2004-08-15
RU2000108443A (ru) 2002-02-10
US20020055484A1 (en) 2002-05-09
US20020128223A1 (en) 2002-09-12
US20040014710A1 (en) 2004-01-22
EP1009412A1 (de) 2000-06-21
NZ503073A (en) 2002-11-26
JP2001516695A (ja) 2001-10-02
CA2302156C (en) 2006-11-21
KR100564789B1 (ko) 2006-03-28
RU2212241C2 (ru) 2003-09-20
DE69825292T2 (de) 2005-05-25
US7935680B2 (en) 2011-05-03
US6551612B2 (en) 2003-04-22
CN1286632A (zh) 2001-03-07
KR20010023578A (ko) 2001-03-26
WO1999011274A1 (en) 1999-03-11
US7338666B2 (en) 2008-03-04
DE69825292D1 (de) 2004-09-02
EP1009412B1 (de) 2004-07-28
CA2302156A1 (en) 1999-03-11
AU748961B2 (en) 2002-06-13
US6440455B1 (en) 2002-08-27
US20070213294A1 (en) 2007-09-13
EP1466606A3 (de) 2004-11-24

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PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20130220