HK1003869A1 - Compositions containing at least one glucocorticoid in combination with a pulmon ary surfactant for the treatment of irds and ards - Google Patents

Compositions containing at least one glucocorticoid in combination with a pulmon ary surfactant for the treatment of irds and ards

Info

Publication number
HK1003869A1
HK1003869A1 HK98103100A HK98103100A HK1003869A1 HK 1003869 A1 HK1003869 A1 HK 1003869A1 HK 98103100 A HK98103100 A HK 98103100A HK 98103100 A HK98103100 A HK 98103100A HK 1003869 A1 HK1003869 A1 HK 1003869A1
Authority
HK
Hong Kong
Prior art keywords
treatment
irds
ards
surfactant
pulmon
Prior art date
Application number
HK98103100A
Other languages
English (en)
Inventor
Paul-Georg Germann
Klaus Eistetter
Ulrich Kilian
Dietrich Haefner
Original Assignee
Altana Pharm Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Altana Pharm Ag filed Critical Altana Pharm Ag
Publication of HK1003869A1 publication Critical patent/HK1003869A1/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/42—Respiratory system, e.g. lungs, bronchi or lung cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/16—Central respiratory analeptics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
    • A61P5/44—Glucocorticosteroids; Drugs increasing or potentiating the activity of glucocorticosteroids

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Zoology (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Cell Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biotechnology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Virology (AREA)
  • Physiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biomedical Technology (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Processes Of Treating Macromolecular Substances (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Steroid Compounds (AREA)
HK98103100A 1994-09-28 1998-04-15 Compositions containing at least one glucocorticoid in combination with a pulmon ary surfactant for the treatment of irds and ards HK1003869A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE4434629A DE4434629C1 (de) 1994-09-28 1994-09-28 Zusammensetzungen zur Behandlung von IRDS und ARDS
PCT/EP1995/003816 WO1996009831A2 (de) 1994-09-28 1995-09-27 Zusammensetzungen zur behandlung von irds und ards, die mindestens ein glucocorticosteroid in kombination mit einem lungen surfactant enthalten

Publications (1)

Publication Number Publication Date
HK1003869A1 true HK1003869A1 (en) 1998-11-13

Family

ID=6529394

Family Applications (1)

Application Number Title Priority Date Filing Date
HK98103100A HK1003869A1 (en) 1994-09-28 1998-04-15 Compositions containing at least one glucocorticoid in combination with a pulmon ary surfactant for the treatment of irds and ards

Country Status (26)

Country Link
US (1) US5891844A (xx)
EP (1) EP0783314B1 (xx)
JP (1) JP4425991B2 (xx)
KR (1) KR100365030B1 (xx)
CN (1) CN1100542C (xx)
AT (1) ATE241372T1 (xx)
AU (1) AU705099B2 (xx)
BG (1) BG62556B1 (xx)
CA (1) CA2201377C (xx)
CZ (1) CZ292846B6 (xx)
DE (2) DE4434629C1 (xx)
DK (1) DK0783314T3 (xx)
EE (1) EE03422B1 (xx)
ES (1) ES2201120T3 (xx)
FI (1) FI118886B (xx)
HK (1) HK1003869A1 (xx)
HU (1) HU226958B1 (xx)
MX (1) MX9702303A (xx)
NO (1) NO313405B1 (xx)
NZ (1) NZ294587A (xx)
PL (1) PL187496B1 (xx)
PT (1) PT783314E (xx)
RU (1) RU2157222C2 (xx)
SK (1) SK284446B6 (xx)
UA (1) UA43378C2 (xx)
WO (1) WO1996009831A2 (xx)

Families Citing this family (39)

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US6039932A (en) * 1996-09-27 2000-03-21 3M Innovative Properties Company Medicinal inhalation aerosol formulations containing budesonide
EA001758B1 (ru) * 1997-02-17 2001-08-27 Бык Гульден Ломберг Хемише Фабрик Гмбх Композиции для лечения респираторного дистресс-синдрома взрослых или респираторного дистресс-синдрома новорожденных, содержащие 3-(циклопропилметокси)-n-(3,5-дихлор-4-пиридинил)-4-(дифторметокси)бензамид и легочное поверхностно-активное вещество
US7122344B2 (en) 1997-05-28 2006-10-17 Claragen, Inc. Methods for the production of purified recombinant human uteroglobin for the treatment of inflammatory and fibrotic conditions
US20060281681A1 (en) 1997-05-28 2006-12-14 Pilon Aprile L Methods and compositions for the reduction of neutrophil influx and for the treatment of bronchpulmonary dysplasia, respiratory distress syndrome, chronic lung disease, pulmonary fibrosis, asthma and chronic obstructive pulmonary disease
US20060165606A1 (en) 1997-09-29 2006-07-27 Nektar Therapeutics Pulmonary delivery particles comprising water insoluble or crystalline active agents
US6309623B1 (en) 1997-09-29 2001-10-30 Inhale Therapeutic Systems, Inc. Stabilized preparations for use in metered dose inhalers
US6946117B1 (en) * 1997-09-29 2005-09-20 Nektar Therapeutics Stabilized preparations for use in nebulizers
US6433040B1 (en) 1997-09-29 2002-08-13 Inhale Therapeutic Systems, Inc. Stabilized bioactive preparations and methods of use
US6565885B1 (en) 1997-09-29 2003-05-20 Inhale Therapeutic Systems, Inc. Methods of spray drying pharmaceutical compositions
US20020017295A1 (en) * 2000-07-07 2002-02-14 Weers Jeffry G. Phospholipid-based powders for inhalation
CN1194833A (zh) * 1997-10-08 1998-10-07 刘柏宏 肺活素
US6858223B2 (en) 1998-06-23 2005-02-22 Altana Pharma Ag Compositions comprising phenylaminothiophenacetic acid derivatives for the treatment of acute or adult respiratory distress syndrome (ARDS) and infant respiratory distress syndrome (IRDS)
AU5400000A (en) * 1999-06-11 2001-01-02 Byk Gulden Lomberg Chemische Fabrik Gmbh Pharmaceutical preparation containing modifications of surfactant protein b (sp-b) and surfactant protein c (sp-c)
AU6083899A (en) * 1999-09-16 2001-04-17 Aventis Behring Gmbh Combination of c1-inh and lung surfactant for the treatment of respiratory disorders
DE19957898A1 (de) * 1999-12-01 2001-06-07 Byk Gulden Lomberg Chem Fab Neue Verwendung von Lungensurfactant
DE10018022A1 (de) * 2000-04-12 2001-10-31 Byk Gulden Lomberg Chem Fab Neue Verwendung von Lungensurfactant zur Prophylaxe oder Frühbehandlung von akuten Lungenerkrankungen
US20040254112A1 (en) * 2000-04-12 2004-12-16 Dietrich Hafner Use of pulmonary surfactant for the early treatment of acute pulmonary diseases
ATE323505T1 (de) * 2000-04-12 2006-05-15 Altana Pharma Ag Verwendung von rekombinantem lungensurfactant zur frühbehandlung von akuten lungenerkrankungen
PT1280520E (pt) * 2000-05-10 2014-12-16 Novartis Ag Pós à base de fosfolípidos para administração de fármacos
US7871598B1 (en) 2000-05-10 2011-01-18 Novartis Ag Stable metal ion-lipid powdered pharmaceutical compositions for drug delivery and methods of use
US8404217B2 (en) 2000-05-10 2013-03-26 Novartis Ag Formulation for pulmonary administration of antifungal agents, and associated methods of manufacture and use
DE10132307A1 (de) * 2001-07-06 2003-01-30 Aventis Behring Gmbh Arzneizubereitung zur Inhalation von Antithrombin bei entzündlichen Lungenerkrankungen und ARDS
US20030099601A1 (en) * 2001-11-27 2003-05-29 Gordon Marc S. Inhalation lung surfactant therapy
WO2003053455A1 (en) * 2001-12-12 2003-07-03 Penn State Research Foundation Surfactant prevention of lung complications from cancer chemotherapy
TWI324518B (en) 2001-12-19 2010-05-11 Nektar Therapeutics Pulmonary delivery of aminoglycosides
US20040023935A1 (en) * 2002-08-02 2004-02-05 Dey, L.P. Inhalation compositions, methods of use thereof, and process for preparation of same
US20040109826A1 (en) * 2002-12-06 2004-06-10 Dey, L.P. Stabilized albuterol compositions and method of preparation thereof
CA2529007C (en) 2003-06-16 2012-03-27 Altana Pharma Ag Composition comprising a pulmonary surfactant and a pde5 inhibitor for the treatment of lung diseases
ES2452691T5 (es) * 2003-09-16 2022-09-14 Covis Pharma Gmbh Uso de ciclesonida para el tratamiento de enfermedades respiratorias
US7582312B2 (en) 2004-11-15 2009-09-01 Discovery Laboratories, Inc. Methods to produce lung surfactant formulations via lyophilization and formulations and uses thereof
US7464012B2 (en) * 2004-12-10 2008-12-09 L'air Liquide, Societe Anonyme A Directoire Et Conseil De Surveillance Pour L'etude Et L'exploitation Des Procedes Georges Claude Simplified process simulator
PL1841458T3 (pl) 2005-01-06 2012-05-31 Discovery Lab Inc Schemat stosowania środka powierzchniowo czynnego do leczenia lub zapobiegania dysplazji oskrzelowo-płucnej
KR100891595B1 (ko) 2005-02-28 2009-04-03 주식회사 케이티앤지 혈액 단백질의 삼출을 감소시키는 조성물
ZA200902487B (en) * 2006-09-19 2010-07-28 Discovery Lab Inc Pulmonary surfactant formulations and methods for promoting mucus clearance
EP2022798A1 (en) * 2007-08-09 2009-02-11 CHIESI FARMACEUTICI S.p.A. Synthetic pulmonary surfactant peptides
WO2012077127A1 (en) * 2010-12-10 2012-06-14 Indian Institute Of Technology, Bombay A protein free surfactant composition for pulmonary diseases and a process for preparing the same
WO2013188016A2 (en) 2012-05-04 2013-12-19 Discovery Laboratories, Inc. Surfactant therapy for exposure to ionizing radiation
CN106310280A (zh) * 2016-08-18 2017-01-11 滨州医学院 地瑞那韦增强糖皮质激素抗炎作用的医药新用途
KR102470549B1 (ko) * 2016-12-22 2022-11-25 키에시 파르마슈티시 엣스. 피. 에이. 발달하는 bpd의 치료를 위한 폐 계면활성제 및 스테로이드를 포함하는 치료 조합물

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4944941A (en) * 1987-08-07 1990-07-31 Genentech, Inc. Methods and compositions for the treatment of lung conditions
US5006343A (en) * 1988-12-29 1991-04-09 Benson Bradley J Pulmonary administration of pharmaceutically active substances

Also Published As

Publication number Publication date
CZ292846B6 (cs) 2003-12-17
CA2201377C (en) 2008-07-29
AU705099B2 (en) 1999-05-13
CN1100542C (zh) 2003-02-05
EP0783314B1 (de) 2003-05-28
EE03422B1 (et) 2001-06-15
JPH10506119A (ja) 1998-06-16
CA2201377A1 (en) 1996-04-04
EP0783314A2 (de) 1997-07-16
KR100365030B1 (ko) 2003-03-10
DK0783314T3 (da) 2003-12-01
SK284446B6 (sk) 2005-04-01
NO971403D0 (no) 1997-03-25
DE4434629C1 (de) 1996-06-27
ES2201120T3 (es) 2004-03-16
BG101441A (en) 1997-09-30
FI971277A (fi) 1997-05-27
NO971403L (no) 1997-04-17
FI118886B (fi) 2008-04-30
WO1996009831A3 (de) 1996-05-23
SK40197A3 (en) 1998-02-04
PL187496B1 (pl) 2004-07-30
FI971277A0 (fi) 1997-03-26
AU3742895A (en) 1996-04-19
DE59510705D1 (de) 2003-07-03
MX9702303A (es) 1997-06-28
PL319608A1 (en) 1997-08-18
NZ294587A (en) 1998-07-28
WO1996009831A2 (de) 1996-04-04
EE9700084A (et) 1997-10-15
JP4425991B2 (ja) 2010-03-03
UA43378C2 (uk) 2001-12-17
CN1163571A (zh) 1997-10-29
NO313405B1 (no) 2002-09-30
HU226958B1 (en) 2010-03-29
US5891844A (en) 1999-04-06
BG62556B1 (bg) 2000-02-29
HUT77931A (hu) 1998-11-30
PT783314E (pt) 2003-10-31
KR970706006A (ko) 1997-11-03
CZ94097A3 (en) 1997-09-17
ATE241372T1 (de) 2003-06-15
RU2157222C2 (ru) 2000-10-10

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Legal Events

Date Code Title Description
PF Patent in force
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20140927