GR78044B - - Google Patents

Info

Publication number
GR78044B
GR78044B GR69335A GR820169335A GR78044B GR 78044 B GR78044 B GR 78044B GR 69335 A GR69335 A GR 69335A GR 820169335 A GR820169335 A GR 820169335A GR 78044 B GR78044 B GR 78044B
Authority
GR
Greece
Prior art keywords
carbon atoms
alkyl
group
aralkyl
aryl
Prior art date
Application number
GR69335A
Other languages
English (en)
Inventor
Wilfred R Tully
Robert Westwood
David A Rowlands
Stephen Clements-Jewery
Original Assignee
Roussel Uclaf
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roussel Uclaf filed Critical Roussel Uclaf
Publication of GR78044B publication Critical patent/GR78044B/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72—Quinazolines; Hydrogenated quinazolines
    • C07D239/95—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in positions 2 and 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72—Quinazolines; Hydrogenated quinazolines
    • C07D239/95—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in positions 2 and 4
    • C07D239/96—Two oxygen atoms

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pulmonology (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Treatments For Attaching Organic Compounds To Fibrous Goods (AREA)
  • Cosmetics (AREA)
GR69335A 1981-09-24 1982-09-22 GR78044B (el)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB8128875 1981-09-24

Publications (1)

Publication Number Publication Date
GR78044B true GR78044B (el) 1984-09-26

Family

ID=10524710

Family Applications (1)

Application Number Title Priority Date Filing Date
GR69335A GR78044B (el) 1981-09-24 1982-09-22

Country Status (18)

Country Link
US (1) US4472400A (el)
EP (1) EP0076199B1 (el)
JP (1) JPS5865292A (el)
AT (1) ATE24509T1 (el)
AU (1) AU554959B2 (el)
CA (1) CA1193597A (el)
DE (1) DE3274860D1 (el)
DK (1) DK160308C (el)
ES (1) ES515904A0 (el)
FI (1) FI73435C (el)
GB (1) GB2108495B (el)
GR (1) GR78044B (el)
HU (1) HU186975B (el)
IE (1) IE53858B1 (el)
IL (1) IL66835A (el)
MA (1) MA19604A1 (el)
PT (1) PT75602B (el)
ZA (1) ZA826891B (el)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5442062A (en) * 1991-10-24 1995-08-15 The Upjohn Company Imidazole derivatives and pharmaceutical compositions containing the same
US5688803A (en) * 1994-05-24 1997-11-18 Hoffmann-La Roche Inc. Tricyclic dicarbonyl derivatives
US5756502A (en) * 1994-08-08 1998-05-26 Warner-Lambert Company Quinazolinone derivatives as cholyecystokinin (CCK) ligands
US6897213B1 (en) 1995-11-21 2005-05-24 Warner-Lambert Company Heterocycles as cholecystokinin (CCK) ligands
CA2319435A1 (en) * 1998-12-04 2000-06-15 Toray Industries, Inc. Triazolo derivatives and chemokine inhibitors containing the same as effective component
FR2792938B1 (fr) * 1999-04-28 2001-07-06 Warner Lambert Co NOUVELLES 1-AMINO TRIAZOLO [4,3-a] QUINAZOLINE-5-ONES INHIBITRICES DE PHOSPHODIESTERASES IV
PA8539501A1 (es) * 2001-02-14 2002-09-30 Warner Lambert Co Compuestos triazolo como inhibidores de mmp
EP1285922A1 (en) 2001-08-13 2003-02-26 Warner-Lambert Company 1-Alkyl or 1-cycloalkyltriazolo[4,3-a]quinazolin-5-ones as phosphodiesterase inhibitors
FR2832711B1 (fr) 2001-11-26 2004-01-30 Warner Lambert Co Derives de triazolo [4,3-a] pyrido [2,3-d] pyrimidin-5-ones, compositions les contenant, procede de preparation et utilisation
CN1891704A (zh) * 2005-07-08 2007-01-10 中国科学院上海药物研究所 一类二肽酶四抑制剂及其制备方法和用途
CN115197225B (zh) * 2021-09-03 2023-04-11 贵州大学 一种五元杂环并喹唑啉酮类化合物及其制备方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS50116498A (el) * 1974-02-27 1975-09-11
US4145419A (en) * 1976-05-21 1979-03-20 Roussel Uclaf Novel imidazobenzoxazines
GB1596652A (en) * 1977-01-20 1981-08-26 Roussel Lab Ltd Imidazo (1,2-a) quinoline-2-carboxylic acid and derivatives
GB1576077A (en) * 1977-04-13 1980-10-01 Roussel Lab Ltd 4,5-dihydro-4-oxophyrrolo(1,2-)-quinoxaline-2-carboxylic acids and derivatives
SE444319B (sv) * 1977-11-18 1986-04-07 Roussel Uclaf Nya imidazobensoxazinderivat, forfarande for framstellning derav och farmaceutiska kompositioner innehallande dessa foreningar
SE439308B (sv) * 1978-08-02 1985-06-10 Roussel Uclaf Imidazo(1,2-a)kinoxaliner och farmaceutiska kompositioner derav
DD139715A1 (de) * 1978-09-29 1980-01-16 Karl Kottke Verfahren zur herstellung von 1-substituierten 4-aryl-s-triazolo(4,3-a)chinazolonen-(5)
IL59104A (en) * 1979-02-09 1984-02-29 Roussel Uclaf Heterotricyclic derivatives,process for their preparation and pharmaceutical compositions incorporating them
FR2448541A1 (fr) * 1979-02-09 1980-09-05 Roussel Uclaf Nouveaux derives de l'oxoimidazoquinoxaline et leurs sels, leur procede de preparation, leur application comme medicaments et les compositions pharmaceutiques les renfermant
ZA81708B (en) * 1980-02-14 1982-06-30 Roussel Uclaf Triazoloquinazolinone derivatives

Also Published As

Publication number Publication date
DK160308B (da) 1991-02-25
DK420682A (da) 1983-03-25
AU554959B2 (en) 1986-09-11
IE53858B1 (en) 1989-03-29
FI73435C (fi) 1987-10-09
IL66835A (en) 1988-05-31
US4472400A (en) 1984-09-18
HU186975B (en) 1985-10-28
CA1193597A (fr) 1985-09-17
PT75602A (fr) 1982-10-01
GB2108495A (en) 1983-05-18
EP0076199B1 (fr) 1986-12-30
DK160308C (da) 1991-07-29
ES8400440A1 (es) 1983-10-16
EP0076199A3 (en) 1984-03-21
JPS5865292A (ja) 1983-04-18
ZA826891B (en) 1983-10-26
FI73435B (fi) 1987-06-30
AU8862382A (en) 1983-03-31
ES515904A0 (es) 1983-10-16
DE3274860D1 (en) 1987-02-05
EP0076199A2 (fr) 1983-04-06
IE822310L (en) 1983-03-24
MA19604A1 (fr) 1983-04-01
ATE24509T1 (de) 1987-01-15
JPH0322389B2 (el) 1991-03-26
IL66835A0 (en) 1982-12-31
FI823278L (fi) 1983-03-25
PT75602B (fr) 1985-12-09
FI823278A0 (fi) 1982-09-23
GB2108495B (en) 1985-07-24

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