GR77769B - - Google Patents
Info
- Publication number
- GR77769B GR77769B GR69959A GR820169959A GR77769B GR 77769 B GR77769 B GR 77769B GR 69959 A GR69959 A GR 69959A GR 820169959 A GR820169959 A GR 820169959A GR 77769 B GR77769 B GR 77769B
- Authority
- GR
- Greece
- Prior art keywords
- disarrangements
- diazacyclopent
- dichlorophenoxy
- ene
- nervous
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D233/20—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D233/22—Radicals substituted by oxygen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Anesthesiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19813149010 DE3149010A1 (de) | 1981-12-10 | 1981-12-10 | (+)-2-(1-(2,6-dichlorphenoxy)-ethyl)-1,3- diazacyclopent-2-en, dessen herstellung und seine verwendung in pharamazeutischen praeparaten |
Publications (1)
Publication Number | Publication Date |
---|---|
GR77769B true GR77769B (el) | 1984-09-25 |
Family
ID=6148419
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GR69959A GR77769B (el) | 1981-12-10 | 1982-12-02 |
Country Status (9)
Country | Link |
---|---|
US (1) | US4443464A (el) |
EP (1) | EP0082364B1 (el) |
JP (1) | JPS58105969A (el) |
AT (1) | ATE19397T1 (el) |
DE (2) | DE3149010A1 (el) |
DK (1) | DK548082A (el) |
GR (1) | GR77769B (el) |
IE (1) | IE54221B1 (el) |
ZA (1) | ZA828744B (el) |
Families Citing this family (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4801617A (en) * | 1987-04-06 | 1989-01-31 | Leclerc Gerard | Iminoimidazolidines useful in lowering intraocular pressure |
US20050282879A1 (en) * | 2004-06-17 | 2005-12-22 | Foad Salehani | Methods and composition for treatment of migraine and symptoms thereof |
CA2691082A1 (en) * | 2007-07-02 | 2009-01-08 | F. Hoffmann-La Roche Ag | 2 -imidazolines having a good affinity to the trace amine associated receptors (taars) |
WO2010016844A1 (en) * | 2008-08-08 | 2010-02-11 | Agean Llc | Lofexidine enantiomers for use as a treatment for cns disease and pathologies and its chiral synthesis |
HRP20171415T4 (hr) | 2009-06-25 | 2023-03-03 | Alkermes Pharma Ireland Limited | Heterociklični spojevi za liječenje neuroloških i psiholoških poremećaja |
WO2010151711A1 (en) | 2009-06-25 | 2010-12-29 | Alkermes, Inc. | Prodrugs of nh-acidic compounds |
US9034867B2 (en) | 2011-03-18 | 2015-05-19 | Alkermes Pharma Ireland Limited | Pharmaceutical compositions comprising sorbitan esters |
NZ722096A (en) | 2011-12-15 | 2016-11-25 | Alkermes Pharma Ireland Ltd | Prodrugs of secondary amine compounds |
JP6471089B2 (ja) | 2012-03-19 | 2019-02-13 | アルカームス ファーマ アイルランド リミテッド | 脂肪酸エステルを含む医薬組成物 |
JP6219918B2 (ja) | 2012-03-19 | 2017-10-25 | アルカームス ファーマ アイルランド リミテッド | グリセロールエステルを含む医薬組成物 |
CA2867137C (en) | 2012-03-19 | 2020-12-08 | Alkermes Pharma Ireland Limited | Pharmaceutical compositions comprising aripiprazole prodrugs and benzyl alcohol |
ES2792149T3 (es) | 2012-09-19 | 2020-11-10 | Alkermes Pharma Ireland Ltd | Composiciones farmacéuticas que tienen estabilidad de almacenamiento mejorada |
MX2016012041A (es) | 2014-03-20 | 2017-01-19 | Alkermes Pharma Ireland Ltd | Formulaciones de aripiprazol que tienen mayores velocidades de inyeccion. |
JP7384812B2 (ja) | 2018-03-05 | 2023-11-21 | アルカームス ファーマ アイルランド リミテッド | アリピプラゾール投与戦略 |
IT201900009777A1 (it) | 2019-06-21 | 2020-12-21 | Procos Spa | Processo per la sintesi di lofexidina |
EP4136075B1 (en) | 2020-04-17 | 2024-06-05 | Medichem, S.A. | Process for the synthesis of lofexidine |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3966757A (en) * | 1967-02-23 | 1976-06-29 | A. Nattermann & Cie Gmbh | Imidazoline derivatives and processes for the production thereof |
DE1695555A1 (de) * | 1967-02-23 | 1970-07-16 | Nordmark Werke Gmbh | Neue Aryloxy-isoalkyl-delta2-imidazoline und deren Saeureadditionssalze sowie Verfahren zu ihrer Herstellung |
JPS5855129B2 (ja) * | 1974-11-21 | 1983-12-08 | 株式会社クラレ | 2−置換または無置換のゲラニル酢酸エステル類の製造方法 |
DE2818367A1 (de) * | 1977-04-29 | 1978-11-02 | Ciba Geigy Ag | Ektoparasitizide |
-
1981
- 1981-12-10 DE DE19813149010 patent/DE3149010A1/de not_active Withdrawn
-
1982
- 1982-04-13 US US06/367,944 patent/US4443464A/en not_active Expired - Fee Related
- 1982-11-25 IE IE2811/82A patent/IE54221B1/en unknown
- 1982-11-26 ZA ZA828744A patent/ZA828744B/xx unknown
- 1982-12-01 AT AT82111097T patent/ATE19397T1/de not_active IP Right Cessation
- 1982-12-01 EP EP82111097A patent/EP0082364B1/de not_active Expired
- 1982-12-01 DE DE8282111097T patent/DE3270806D1/de not_active Expired
- 1982-12-02 GR GR69959A patent/GR77769B/el unknown
- 1982-12-09 JP JP57214752A patent/JPS58105969A/ja active Pending
- 1982-12-09 DK DK548082A patent/DK548082A/da not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
IE822811L (en) | 1983-06-10 |
DE3270806D1 (en) | 1986-05-28 |
ATE19397T1 (de) | 1986-05-15 |
US4443464A (en) | 1984-04-17 |
EP0082364B1 (de) | 1986-04-23 |
EP0082364A3 (en) | 1984-04-04 |
DE3149010A1 (de) | 1983-07-07 |
DK548082A (da) | 1983-06-11 |
JPS58105969A (ja) | 1983-06-24 |
ZA828744B (en) | 1983-09-28 |
IE54221B1 (en) | 1989-07-19 |
EP0082364A2 (de) | 1983-06-29 |
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