GR20020100196A - Method and kit for the quantitave measurement of serum levels of clusterin/apolipoprotein j - Google Patents
Method and kit for the quantitave measurement of serum levels of clusterin/apolipoprotein jInfo
- Publication number
- GR20020100196A GR20020100196A GR20020100196A GR2002100196A GR20020100196A GR 20020100196 A GR20020100196 A GR 20020100196A GR 20020100196 A GR20020100196 A GR 20020100196A GR 2002100196 A GR2002100196 A GR 2002100196A GR 20020100196 A GR20020100196 A GR 20020100196A
- Authority
- GR
- Greece
- Prior art keywords
- serum levels
- enzyme
- clusterin
- apolipoprotein
- kit
- Prior art date
Links
Landscapes
- Investigating Or Analysing Biological Materials (AREA)
Abstract
his invention combines various technologies and renders the relative quantitative measurement of the of serum levels of Clusterin/Apolipoprotein J. It concerns a variation - adaptation of the ELISA methodology using two antibodies of which the second is conjugated chemically to the enzyme horseradish peroxidase (HRP, tracing enzyme) via which, by chromatic reaction, the serum levels of ApoJ are detected. Alternatively, it is possible that the second antibody does not bear the HRP enzyme conjugated to it, in which case, a third antibody is used against the Fc region of the species where the second antibody against ApoJ has been developed, which bears the HRP enzyme conjugated to it. The kit may be used for the prognosis in patients with diabetes type II or heart coronary disease, for the detection of vascular damage.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GR20020100196A GR1004477B (en) | 2002-04-23 | 2002-04-23 | Method and kit for the quantitave measurement of serum levels of clusterin/apolipoprotein j |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GR20020100196A GR1004477B (en) | 2002-04-23 | 2002-04-23 | Method and kit for the quantitave measurement of serum levels of clusterin/apolipoprotein j |
Publications (2)
Publication Number | Publication Date |
---|---|
GR20020100196A true GR20020100196A (en) | 2003-12-22 |
GR1004477B GR1004477B (en) | 2004-03-08 |
Family
ID=29764772
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GR20020100196A GR1004477B (en) | 2002-04-23 | 2002-04-23 | Method and kit for the quantitave measurement of serum levels of clusterin/apolipoprotein j |
Country Status (1)
Country | Link |
---|---|
GR (1) | GR1004477B (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN104280552A (en) * | 2013-07-12 | 2015-01-14 | 张曼 | Application of urine apolipoprotein J precursor protein |
Citations (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4722893A (en) * | 1983-07-06 | 1988-02-02 | Shiraimatsu Shinyaku Kabushiki Kaisha | Reagents for enzyme immunoassay for apolipoprotein B |
EP0301667A1 (en) * | 1987-07-28 | 1989-02-01 | Istituto Sieroterapico Milanese "S. Belfanti" | Method for the immunoassay of apolipoproteins |
JPH0244253A (en) * | 1988-08-04 | 1990-02-14 | Tosoh Corp | Measurement of apolipoprotein a-i |
EP0621284A1 (en) * | 1992-08-14 | 1994-10-26 | Shino-Test Corporation | PEPTIDES CONTAINING RESPECTIVE AMINO ACID SEQUENCES SELECTED FROM AMONG THOSE OF LIPOPROTEIN(a) AND APOLIPOPROTEIN(a), ANTIBODIES RESPECTIVELY RECOGNIZING THESE AMINO ACID SEQUENCES, AND METHOD OF ASSAYING WITH THESE ANTIBODIES |
WO1996032502A1 (en) * | 1995-04-11 | 1996-10-17 | The Trustees Of Columbia University In The City Of New York | Reagent specific for apolipoprotein-j polymorphisms and uses thereof |
WO1999004260A1 (en) * | 1997-07-15 | 1999-01-28 | Bioprobes, Inc. | Determining alcohol intake using sialic acid/apo j |
US6197596B1 (en) * | 1997-12-04 | 2001-03-06 | Mcgill University | Monitoring and/or prognostic of antibody-mediated autoimmune diseases |
-
2002
- 2002-04-23 GR GR20020100196A patent/GR1004477B/en unknown
Patent Citations (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4722893A (en) * | 1983-07-06 | 1988-02-02 | Shiraimatsu Shinyaku Kabushiki Kaisha | Reagents for enzyme immunoassay for apolipoprotein B |
EP0301667A1 (en) * | 1987-07-28 | 1989-02-01 | Istituto Sieroterapico Milanese "S. Belfanti" | Method for the immunoassay of apolipoproteins |
JPH0244253A (en) * | 1988-08-04 | 1990-02-14 | Tosoh Corp | Measurement of apolipoprotein a-i |
EP0621284A1 (en) * | 1992-08-14 | 1994-10-26 | Shino-Test Corporation | PEPTIDES CONTAINING RESPECTIVE AMINO ACID SEQUENCES SELECTED FROM AMONG THOSE OF LIPOPROTEIN(a) AND APOLIPOPROTEIN(a), ANTIBODIES RESPECTIVELY RECOGNIZING THESE AMINO ACID SEQUENCES, AND METHOD OF ASSAYING WITH THESE ANTIBODIES |
WO1996032502A1 (en) * | 1995-04-11 | 1996-10-17 | The Trustees Of Columbia University In The City Of New York | Reagent specific for apolipoprotein-j polymorphisms and uses thereof |
WO1999004260A1 (en) * | 1997-07-15 | 1999-01-28 | Bioprobes, Inc. | Determining alcohol intake using sialic acid/apo j |
US6197596B1 (en) * | 1997-12-04 | 2001-03-06 | Mcgill University | Monitoring and/or prognostic of antibody-mediated autoimmune diseases |
Non-Patent Citations (1)
Title |
---|
PATENT ABSTRACTS OF JAPAN vol. 014, no. 204 (P - 1042) 25 April 1990 (1990-04-25) * |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN104280552A (en) * | 2013-07-12 | 2015-01-14 | 张曼 | Application of urine apolipoprotein J precursor protein |
Also Published As
Publication number | Publication date |
---|---|
GR1004477B (en) | 2004-03-08 |
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