GR1006794B - Προσδετες των σιγμα υποδοχεων, αντι-αποπτωτικες και προ-αποπτωτικες ιδιοτητες επι των κυτταρικων μηχανισμων, και με πρωτοτυπη κυτταρο-προστατευτικη αλλα και αντικαρκινικη δραση - Google Patents
Προσδετες των σιγμα υποδοχεων, αντι-αποπτωτικες και προ-αποπτωτικες ιδιοτητες επι των κυτταρικων μηχανισμων, και με πρωτοτυπη κυτταρο-προστατευτικη αλλα και αντικαρκινικη δρασηInfo
- Publication number
- GR1006794B GR1006794B GR20090100115A GR20090100115A GR1006794B GR 1006794 B GR1006794 B GR 1006794B GR 20090100115 A GR20090100115 A GR 20090100115A GR 20090100115 A GR20090100115 A GR 20090100115A GR 1006794 B GR1006794 B GR 1006794B
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- Prior art keywords
- apoptotic
- metastatic
- chronic
- pro
- cancer
- Prior art date
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
- A61K31/341—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide not condensed with another ring, e.g. ranitidine, furosemide, bufetolol, muscarine
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
- A61K31/343—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide condensed with a carbocyclic ring, e.g. coumaran, bufuralol, befunolol, clobenfurol, amiodarone
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/365—Lactones
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/429—Thiazoles condensed with heterocyclic ring systems
- A61K31/43—Compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula, e.g. penicillins, penems
- A61K31/431—Compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula, e.g. penicillins, penems containing further heterocyclic rings, e.g. ticarcillin, azlocillin, oxacillin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4453—Non condensed piperidines, e.g. piperocaine only substituted in position 1, e.g. propipocaine, diperodon
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/4525—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with oxygen as a ring hetero atom
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
- A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
- A61K31/5415—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with carbocyclic ring systems, e.g. phenothiazine, chlorpromazine, piroxicam
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/64—Sulfonylureas, e.g. glibenclamide, tolbutamide, chlorpropamide
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Emergency Medicine (AREA)
- Oncology (AREA)
- Virology (AREA)
- Communicable Diseases (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Η εφεύρεση αφορά νέους και πρωτότυπους συνδέτες των υποδοχέων σίγμα : (Μονό - ή δι-αλκύλαμινόαλκυλ) γ - βουτυρολακτόνες, τα ανάλογα τους αμινοτετραϋδροφουράνια, οι (1 - αδαμαντύλ) φαινύλ αλκυλαμίνες, οι Ν, Ν Διαλκυλ α-[(αδαμαντυλ - 1) βενζυλοξύ - 2] αλκυλαμίνες και οι 3 - κυκλοπεντύλ αδαμαντύλ -αμίνες ή - αλκυλαμίνες ή - αλκύλ φαινυλαμίνες, τα εναντιομερή τους ή τα διαστερεοϊσομερή τους και τα φαρμακευτικώς αποδεκτά τους άλατα, με προ-αποπτωτικές και αντι-αποπτωτικές ιδιότητες επί των κυτταρικών βιοχημικών μηχανισμών, και με αντικαρκινική, αντιμεταστατική, αντί-(χρονιό) φλεγμονική, νευροπροστατευτική, αντισπασμωδική, αντικαταθλιπτική, κυτταρο-προστατευτική κατά των κυτταρο-εκφυλιστικών ασθενειών και αναλγητική κατά του νευροπαθητικού πόνου.
Priority Applications (7)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GR20090100115A GR1006794B (el) | 2009-02-26 | 2009-02-26 | Προσδετες των σιγμα υποδοχεων, αντι-αποπτωτικες και προ-αποπτωτικες ιδιοτητες επι των κυτταρικων μηχανισμων, και με πρωτοτυπη κυτταρο-προστατευτικη αλλα και αντικαρκινικη δραση |
PCT/GR2010/000009 WO2010097641A1 (en) | 2009-02-26 | 2010-02-17 | SIGMA(σ) RECEPTORS LIGANDS WITH ANTI-APOPTOTIC AND/OR PRO-APOPTOTIC PROPERTIES, OVER CELLULAR MECHANISMS, EXHIBITING PROTOTYPICAL CYTOPROTECTIVE AND ALSO ANTICANCER ACTIVITY |
CN2010800090296A CN102325529A (zh) | 2009-02-26 | 2010-02-17 | 显示原型细胞保护活性并且还显示抗癌活性的在细胞机制方面具有促凋亡和/或抗凋亡特性的西格玛(σ)受体 |
RU2011131708/04A RU2011131708A (ru) | 2009-02-26 | 2010-02-17 | Лиганды сигма рецепторов с противоапоптическими и/или проапоптическими свойствами за счет клеточных механизмов, проявляющие прототипную цитопротекторную, а также противораковую активность |
EP10706348A EP2400965A1 (en) | 2009-02-26 | 2010-02-17 | Sigma( ) receptors ligands with anti-apoptotic and/or pro-apoptotic properties, over cellular mechanisms, exhibiting prototypical cytoprotective and also anticancer activity |
US13/201,271 US20110301154A1 (en) | 2009-02-26 | 2010-02-17 | Sigma receptors ligands with anti-apoptotic and/or pro-apoptotic properties, over cellular mechanisms, exhibiting prototypical cytoprotective and also anticancer activity |
US14/205,637 US9180106B2 (en) | 2009-02-26 | 2014-03-12 | Sigma receptors ligands with anti-apoptotic and/or pro-apoptotic properties, over cellular mechanisms, exhibiting prototypical cytoprotective and also anti-cancer activity |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GR20090100115A GR1006794B (el) | 2009-02-26 | 2009-02-26 | Προσδετες των σιγμα υποδοχεων, αντι-αποπτωτικες και προ-αποπτωτικες ιδιοτητες επι των κυτταρικων μηχανισμων, και με πρωτοτυπη κυτταρο-προστατευτικη αλλα και αντικαρκινικη δραση |
Publications (1)
Publication Number | Publication Date |
---|---|
GR1006794B true GR1006794B (el) | 2010-06-04 |
Family
ID=42083964
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GR20090100115A GR1006794B (el) | 2009-02-26 | 2009-02-26 | Προσδετες των σιγμα υποδοχεων, αντι-αποπτωτικες και προ-αποπτωτικες ιδιοτητες επι των κυτταρικων μηχανισμων, και με πρωτοτυπη κυτταρο-προστατευτικη αλλα και αντικαρκινικη δραση |
Country Status (6)
Country | Link |
---|---|
US (2) | US20110301154A1 (el) |
EP (1) | EP2400965A1 (el) |
CN (1) | CN102325529A (el) |
GR (1) | GR1006794B (el) |
RU (1) | RU2011131708A (el) |
WO (1) | WO2010097641A1 (el) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GR1009143B (el) * | 2016-07-14 | 2017-10-20 | Αλεξανδρος Δημητριου Βαμβακιδης | Πρωτοτυπη θεραπευτικη δραση επιλεγμενων αμινοτετραϋδροφουρανιων κατα των νευροεκφυλιστικων και των διαχυτων νευροαναπτυξιακων ασθενειων |
US10888543B2 (en) | 2016-01-26 | 2021-01-12 | Anavex Life Sciences Corp. | Neurodevelopmental disorder therapy |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GR1007322B (el) * | 2010-03-09 | 2011-06-22 | Βαμβακιδης, Αλεξανδρος Δημητριου | Συνθεση της 1-μεθυλο-4-[4,4-διφαινυλο-4-(1-αδαμαντυλο-βουτυλο] πιπεραζινης και δομικων της αναλογων με αντικαρκινικες ιδιοτητες |
GR1007686B (el) * | 2011-07-08 | 2012-09-12 | Αλεξανδρος Δημητριου Βαμβακιδης | Συνθεση των (+) και (-) 1-(5,5-διφαινυλοτετραϋδροφουραν-3-υλ)-ν,ν-διμεθυλομεθυλαμινης, (+) και (-) 1-(2,2-διφαινυλοτετραϋδροφουραν-3-υλ)-ν,ν-διμεθυλομεθυλαμινης και (+) και (-) 1-(2,2-διφαινυλοτετραϋδροφουραν-3-υλ)-ν-μεθυλομεθυλαμινης |
CA2904045C (en) | 2013-03-13 | 2022-03-29 | Tris Pharma, Inc. | Benzonatate modified release solid tablets and capsules |
JP7304043B2 (ja) * | 2015-07-22 | 2023-07-06 | アナベックス ライフ サイエンシズ コーポレイション | テトラヒドロ-n,n-ジメチル-2,2-ジフェニル-3-フランメタンアミンヒドロクロリドの結晶形態、かかる形態の作製方法およびその薬学的組成物 |
US11938224B1 (en) | 2016-04-08 | 2024-03-26 | Tris Pharma Inc | Benzonatate modified release solid tablets and capsules |
US10195192B2 (en) * | 2016-11-01 | 2019-02-05 | Anavex Life Sciences Corp. | Analgesic therapeutic and method, 1-(3-4(((1R,3S,5S)-adamantan-1-yl)(phenyl)methyl)propyl)-4-methylpiperazine and salts thereof |
US11548893B2 (en) | 2017-07-15 | 2023-01-10 | Arisan Therapeutics Inc. | Enantiomerically pure adamantane carboxamides for the treatment of filovirus infection |
WO2024094156A1 (zh) * | 2022-11-04 | 2024-05-10 | 石药集团中奇制药技术(石家庄)有限公司 | 胺类化合物及其用途 |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9323399D0 (en) * | 1993-11-12 | 1994-01-05 | Univ Newcastle Ventures Ltd | Pharmaceutical formulations |
GR1002616B (el) | 1996-02-21 | 1997-02-20 | Συνθεση και μεθοδος συνθεσης μοριου: τετραυδρο-ν,ν-διμεθυλο-2,2-διφαινυλο-3-φουρανομεθαναμινης (αε 37), αντισπασμωδικης, αντικαταθλιπτικης και νοοτροπικης δρασης. | |
FR2794742B1 (fr) * | 1999-06-11 | 2005-06-03 | Sanofi Synthelabo | Nouveaux derives du benzene, un procede pour leur preparation et les compositions pharmaceutiques les contenant |
GR1004208B (en) * | 2001-10-15 | 2003-04-04 | Αλεξανδρος Βαμβακιδης | Aminotetrahydrofuran derivatives, muscarinic/sigma/sodium channel ligands, with synergic sigma/muscarinic (neuroactivating) and sigma/sodium channel (neuroprotective) components, as prototypical activating - neuroprotectors and neuroregenerative drugs |
GR1004868B (el) | 2003-04-22 | 2005-04-26 | Αλεξανδρος Βαμβακιδης | Αμινοτετραυδροφουρανικα παραγωγα με τριπλη χημικη συγγενεια (μουσκαρινικη/σιγμα/υποδοχεων/ διαυλων νατριου) με ορθο- και αλλοστeρικη δραση σαν πρωτοτυπα νευρορυθμιστικα και νευροαναενωτικα φαρμακα. |
WO2006012419A2 (en) * | 2004-07-20 | 2006-02-02 | Cleveland Clinic Foundation | Inhibition of nf-kb |
US20060019968A1 (en) * | 2004-07-24 | 2006-01-26 | Laboratorios Dr. Esteve S.A. | Use of compounds active on the sigma receptor for the treatment of neuropathic pain |
US20090325975A1 (en) * | 2005-07-15 | 2009-12-31 | Helmut H Buschmann | Use of compounds binding to the sigma receptor for the treatment of diabetes-associated pain |
FR2897535B1 (fr) * | 2006-02-21 | 2012-07-20 | Alexandre Vamvakides | Les sigma ligands : (mono- ou di-alkylaminoalkyl)-y- butyrolactones, leurs analogues aminotetrodrafuranes et les (1-adamantyl) benzene(s) alkylamines en tant que modulateurs prototypiques des recepteurs cellulaires |
GR1005865B (el) * | 2007-01-17 | 2008-04-07 | Anavex Life Sciences Corp. | Νεοι συνδετες των σιγμα υποδοχεων με αντι-αποπτωτικες και/η προ-αποπτωτικες ιδιοτητες επι των κυτταρικων βιοχημικων μηχανισμων, με νευρο-προστατευτικη, αντικαρκινικη, αντι-μεταστατικη και αντι- αντι-(χρονιο)φλεγμονικη δραση. |
US20090326895A1 (en) | 2008-06-30 | 2009-12-31 | Beasley Craig J | Technique and system for seismic source separation |
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2009
- 2009-02-26 GR GR20090100115A patent/GR1006794B/el not_active IP Right Cessation
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2010
- 2010-02-17 CN CN2010800090296A patent/CN102325529A/zh active Pending
- 2010-02-17 WO PCT/GR2010/000009 patent/WO2010097641A1/en active Application Filing
- 2010-02-17 EP EP10706348A patent/EP2400965A1/en not_active Withdrawn
- 2010-02-17 US US13/201,271 patent/US20110301154A1/en not_active Abandoned
- 2010-02-17 RU RU2011131708/04A patent/RU2011131708A/ru not_active Application Discontinuation
-
2014
- 2014-03-12 US US14/205,637 patent/US9180106B2/en active Active
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US10888543B2 (en) | 2016-01-26 | 2021-01-12 | Anavex Life Sciences Corp. | Neurodevelopmental disorder therapy |
US11446275B2 (en) | 2016-01-26 | 2022-09-20 | Anavex Life Sciences Corp. | Neurodevelopmental disorder therapy |
US11839600B2 (en) | 2016-01-26 | 2023-12-12 | Anavex Life Sciences Corp. | Neurodevelopmental disorder therapy |
GR1009143B (el) * | 2016-07-14 | 2017-10-20 | Αλεξανδρος Δημητριου Βαμβακιδης | Πρωτοτυπη θεραπευτικη δραση επιλεγμενων αμινοτετραϋδροφουρανιων κατα των νευροεκφυλιστικων και των διαχυτων νευροαναπτυξιακων ασθενειων |
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CN102325529A (zh) | 2012-01-18 |
US20140228375A1 (en) | 2014-08-14 |
US20110301154A1 (en) | 2011-12-08 |
WO2010097641A1 (en) | 2010-09-02 |
EP2400965A1 (en) | 2012-01-04 |
RU2011131708A (ru) | 2013-04-10 |
US9180106B2 (en) | 2015-11-10 |
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