GR1006568B - Method and system for recording of, and aiding in, the regeneration of a peripheral nerve. - Google Patents
Method and system for recording of, and aiding in, the regeneration of a peripheral nerve.Info
- Publication number
- GR1006568B GR1006568B GR20080100282A GR20080100282A GR1006568B GR 1006568 B GR1006568 B GR 1006568B GR 20080100282 A GR20080100282 A GR 20080100282A GR 20080100282 A GR20080100282 A GR 20080100282A GR 1006568 B GR1006568 B GR 1006568B
- Authority
- GR
- Greece
- Prior art keywords
- regeneration
- nerve
- recording
- electronic unit
- aiding
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/326—Applying electric currents by contact electrodes alternating or intermittent currents for promoting growth of cells, e.g. bone cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/02—Details
- A61N1/04—Electrodes
- A61N1/05—Electrodes for implantation or insertion into the body, e.g. heart electrode
- A61N1/0551—Spinal or peripheral nerve electrodes
- A61N1/0556—Cuff electrodes
Abstract
Method and system for the recording of, and aiding in, the regeneration of peripheral nerves after injury, which comprise a stimulation electrode which can be implanted in the central part of the nerve, at least one recording electrode which can beimplanted in the peripheral part of the nerve, an implantable electronic unit, an implantable device that releases regeneration-stimulating agents, such as a micro-pump, and a computational unit which is preferably positioned extra-corporeally for the transmission of data and energy to the electronic unit. The electric signals produced by the peripheral part of the injured nerve, after suitable electric stimulation of the central part thereof, are recorded on various time moments. The analysis of the recorded electric signals is used for the evaluation of the state and progress of the axons under regeneration, from which evaluation various control parameters are determined. The said parameters are used by the electronic unit in order to adjust the release of the stimulating agents so that the therapy is effective, maintaining at the same time the administration of agents at safe levels.
Priority Applications (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GR20080100282A GR1006568B (en) | 2008-04-22 | 2008-04-22 | Method and system for recording of, and aiding in, the regeneration of a peripheral nerve. |
PCT/GR2009/000024 WO2009130515A2 (en) | 2008-04-22 | 2009-04-15 | Method and system for recording and promoting peripheral nerve regeneration |
EP09734126A EP2307090A2 (en) | 2008-04-22 | 2009-04-15 | Method and system for recording and promoting peripheral nerve regeneration |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GR20080100282A GR1006568B (en) | 2008-04-22 | 2008-04-22 | Method and system for recording of, and aiding in, the regeneration of a peripheral nerve. |
Publications (1)
Publication Number | Publication Date |
---|---|
GR1006568B true GR1006568B (en) | 2009-10-13 |
Family
ID=40585045
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GR20080100282A GR1006568B (en) | 2008-04-22 | 2008-04-22 | Method and system for recording of, and aiding in, the regeneration of a peripheral nerve. |
Country Status (3)
Country | Link |
---|---|
EP (1) | EP2307090A2 (en) |
GR (1) | GR1006568B (en) |
WO (1) | WO2009130515A2 (en) |
Families Citing this family (28)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US10588524B2 (en) * | 2011-05-13 | 2020-03-17 | Saluda Medical Pty Ltd | Method and apparatus for measurement of neural response |
JP6243328B2 (en) | 2011-05-13 | 2017-12-06 | サルーダ・メディカル・ピーティーワイ・リミテッド | Method and apparatus for controlling neural stimulation |
US9872990B2 (en) | 2011-05-13 | 2018-01-23 | Saluda Medical Pty Limited | Method and apparatus for application of a neural stimulus |
US10568559B2 (en) | 2011-05-13 | 2020-02-25 | Saluda Medical Pty Ltd | Method and apparatus for measurement of neural response |
CN103648583B (en) | 2011-05-13 | 2016-01-20 | 萨鲁达医疗有限公司 | For measuring method and the instrument of nerves reaction-A |
US9974455B2 (en) | 2011-05-13 | 2018-05-22 | Saluda Medical Pty Ltd. | Method and apparatus for estimating neural recruitment |
US9155892B2 (en) | 2011-05-13 | 2015-10-13 | Saluda Medical Pty Limited | Method and apparatus for application of a neural stimulus |
DK2908904T3 (en) | 2012-11-06 | 2020-12-14 | Saluda Medical Pty Ltd | SYSTEM FOR CONTROLING THE ELECTRICAL CONDITION OF TISSUE |
WO2015070281A1 (en) | 2013-11-15 | 2015-05-21 | Saluda Medical Pty Ltd | Monitoring brain neural potentials |
AU2014353891B2 (en) | 2013-11-22 | 2020-02-06 | Saluda Medical Pty Ltd | Method and device for detecting a neural response in a neural measurement |
US10368762B2 (en) | 2014-05-05 | 2019-08-06 | Saluda Medical Pty Ltd. | Neural measurement |
DK3171929T3 (en) | 2014-07-25 | 2021-05-25 | Saluda Medical Pty Ltd | DOSAGE FOR NERVE STIMULATION |
US10597636B2 (en) | 2014-09-19 | 2020-03-24 | University Of Florida Research Foundation, Inc. | Electroactive polymeric scaffolds and method for delivering nerve growth factor to nerve tissue |
EP3215216A4 (en) | 2014-11-17 | 2018-08-22 | Saluda Medical Pty Ltd | Method and device for detecting a neural response in neural measurements |
AU2015362075B2 (en) | 2014-12-11 | 2021-03-11 | Saluda Medical Pty Ltd | Implantable electrode positioning |
EP4285985A3 (en) | 2014-12-11 | 2024-01-17 | Saluda Medical Pty Ltd | Method and device for feedback control of neural stimulation |
AU2016208972B2 (en) | 2015-01-19 | 2021-06-24 | Saluda Medical Pty Ltd | Method and device for neural implant communication |
US10894158B2 (en) | 2015-04-09 | 2021-01-19 | Saluda Medical Pty Ltd | Electrode to nerve distance estimation |
CA2983336A1 (en) | 2015-05-31 | 2016-12-08 | Saluda Medical Pty Ltd | Monitoring brain neural activity |
WO2016191807A1 (en) | 2015-05-31 | 2016-12-08 | Saluda Medical Pty Ltd | Brain neurostimulator electrode fitting |
CA2980482C (en) | 2015-06-01 | 2023-09-26 | Saluda Medical Pty Ltd | Motor fibre neuromodulation |
US11191966B2 (en) | 2016-04-05 | 2021-12-07 | Saluda Medical Pty Ltd | Feedback control of neuromodulation |
US11179091B2 (en) | 2016-06-24 | 2021-11-23 | Saluda Medical Pty Ltd | Neural stimulation for reduced artefact |
WO2018232145A1 (en) * | 2017-06-14 | 2018-12-20 | Wichita State University | Apparatus and method for neural regeneration |
AU2018354250A1 (en) | 2017-10-25 | 2020-06-11 | Epineuron Technologies Inc. | Systems and methods for delivering neuroregenerative therapy |
US10589089B2 (en) | 2017-10-25 | 2020-03-17 | Epineuron Technologies Inc. | Systems and methods for delivering neuroregenerative therapy |
EP3784338A4 (en) | 2018-04-27 | 2022-01-19 | Saluda Medical Pty Ltd | Neurostimulation of mixed nerves |
US11364381B2 (en) | 2019-10-01 | 2022-06-21 | Epineuron Technologies Inc. | Methods for delivering neuroregenerative therapy and reducing post-operative and chronic pain |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20060089751A1 (en) * | 1997-01-27 | 2006-04-27 | Ewa Herbst | Electronic delivery systems and methods with feedback |
US20060194724A1 (en) * | 2005-02-25 | 2006-08-31 | Whitehurst Todd K | Methods and systems for nerve regeneration |
WO2006108262A2 (en) * | 2005-04-15 | 2006-10-19 | Lozano Andres M | Regulation of neurotrophins |
WO2008005843A2 (en) * | 2006-06-30 | 2008-01-10 | Cyberkinetics Neurotechnology Systems, Inc. | Nerve regeneration system and lead devices associated therewith |
-
2008
- 2008-04-22 GR GR20080100282A patent/GR1006568B/en not_active IP Right Cessation
-
2009
- 2009-04-15 WO PCT/GR2009/000024 patent/WO2009130515A2/en active Application Filing
- 2009-04-15 EP EP09734126A patent/EP2307090A2/en not_active Withdrawn
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20060089751A1 (en) * | 1997-01-27 | 2006-04-27 | Ewa Herbst | Electronic delivery systems and methods with feedback |
US20060194724A1 (en) * | 2005-02-25 | 2006-08-31 | Whitehurst Todd K | Methods and systems for nerve regeneration |
WO2006108262A2 (en) * | 2005-04-15 | 2006-10-19 | Lozano Andres M | Regulation of neurotrophins |
WO2008005843A2 (en) * | 2006-06-30 | 2008-01-10 | Cyberkinetics Neurotechnology Systems, Inc. | Nerve regeneration system and lead devices associated therewith |
Also Published As
Publication number | Publication date |
---|---|
WO2009130515A3 (en) | 2010-04-01 |
EP2307090A2 (en) | 2011-04-13 |
WO2009130515A2 (en) | 2009-10-29 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PG | Patent granted | ||
ML | Lapse due to non-payment of fees |
Effective date: 20131104 |