GR1006042B - Μεθοδος για την κατασκευη μικροσυστοιχιας - Google Patents

Μεθοδος για την κατασκευη μικροσυστοιχιας

Info

Publication number
GR1006042B
GR1006042B GR20070100394A GR20070100394A GR1006042B GR 1006042 B GR1006042 B GR 1006042B GR 20070100394 A GR20070100394 A GR 20070100394A GR 20070100394 A GR20070100394 A GR 20070100394A GR 1006042 B GR1006042 B GR 1006042B
Authority
GR
Greece
Prior art keywords
mikroarray
making
biomolecule
selective
microarrrays
Prior art date
Application number
GR20070100394A
Other languages
English (en)
Inventor
Αγγελικη Τσερεπη
Ευαγγελος Γογγολιδης
Σωτηριος Κακαμπακος
Παναγιωτα Πετρου
Πηνελοπη Μπαγιατη
Ευρυμαχος Ματρωζος
Original Assignee
Εθνικο Κεντρο Ερευνας Φυσικων Επιστημων (Ε.Κ.Ε.Φ.Ε.)-Δημοκριτος
Αγγελικη Τσερεπη
Ευαγγελος Γογγολιδης
Σωτηριος Κακαμπακος
Παναγιωτα Πετρου
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Εθνικο Κεντρο Ερευνας Φυσικων Επιστημων (Ε.Κ.Ε.Φ.Ε.)-Δημοκριτος, Αγγελικη Τσερεπη, Ευαγγελος Γογγολιδης, Σωτηριος Κακαμπακος, Παναγιωτα Πετρου filed Critical Εθνικο Κεντρο Ερευνας Φυσικων Επιστημων (Ε.Κ.Ε.Φ.Ε.)-Δημοκριτος
Priority to GR20070100394A priority Critical patent/GR1006042B/el
Priority to EP08762641.2A priority patent/EP2173474B1/en
Priority to PCT/GR2008/000048 priority patent/WO2008155585A1/en
Priority to US12/665,817 priority patent/US20100248993A1/en
Publication of GR1006042B publication Critical patent/GR1006042B/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B40/00—Libraries per se, e.g. arrays, mixtures
    • C40B40/04—Libraries containing only organic compounds
    • C40B40/06—Libraries containing nucleotides or polynucleotides, or derivatives thereof
    • C40B40/08—Libraries containing RNA or DNA which encodes proteins, e.g. gene libraries
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J19/0046—Sequential or parallel reactions, e.g. for the synthesis of polypeptides or polynucleotides; Apparatus and devices for combinatorial chemistry or for making molecular arrays
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M1/00—Apparatus for enzymology or microbiology
    • C12M1/16—Apparatus for enzymology or microbiology containing, or adapted to contain, solid media
    • C12M1/18—Multiple fields or compartments
    • C12M1/20—Horizontal planar fields
    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B40/00—Libraries per se, e.g. arrays, mixtures
    • C40B40/04—Libraries containing only organic compounds
    • C40B40/10—Libraries containing peptides or polypeptides, or derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B50/00—Methods of creating libraries, e.g. combinatorial synthesis
    • C40B50/14—Solid phase synthesis, i.e. wherein one or more library building blocks are bound to a solid support during library creation; Particular methods of cleavage from the solid support
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277—Apparatus
    • B01J2219/00351—Means for dispensing and evacuation of reagents
    • B01J2219/00427—Means for dispensing and evacuation of reagents using masks
    • B01J2219/00432—Photolithographic masks
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277—Apparatus
    • B01J2219/00497—Features relating to the solid phase supports
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277—Apparatus
    • B01J2219/00497—Features relating to the solid phase supports
    • B01J2219/00527—Sheets
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583—Features relative to the processes being carried out
    • B01J2219/00585—Parallel processes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583—Features relative to the processes being carried out
    • B01J2219/00596—Solid-phase processes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583—Features relative to the processes being carried out
    • B01J2219/00603—Making arrays on substantially continuous surfaces
    • B01J2219/00605—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583—Features relative to the processes being carried out
    • B01J2219/00603—Making arrays on substantially continuous surfaces
    • B01J2219/00659—Two-dimensional arrays
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583—Features relative to the processes being carried out
    • B01J2219/00603—Making arrays on substantially continuous surfaces
    • B01J2219/00664—Three-dimensional arrays
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583—Features relative to the processes being carried out
    • B01J2219/00603—Making arrays on substantially continuous surfaces
    • B01J2219/00677—Ex-situ synthesis followed by deposition on the substrate
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/0068—Means for controlling the apparatus of the process
    • B01J2219/00686—Automatic
    • B01J2219/00691—Automatic using robots
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00718—Type of compounds synthesised
    • B01J2219/0072—Organic compounds
    • B01J2219/00722—Nucleotides
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00718—Type of compounds synthesised
    • B01J2219/0072—Organic compounds
    • B01J2219/00725—Peptides
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00718—Type of compounds synthesised
    • B01J2219/0072—Organic compounds
    • B01J2219/00734—Lipids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Structural Engineering (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Sustainable Development (AREA)
  • General Engineering & Computer Science (AREA)
  • Clinical Laboratory Science (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Peptides Or Proteins (AREA)

Abstract

Αυτή η ευρεσιτεχνία παρέχει μια μέθοδο για σχηματοποίηση πρωτεϊνών και κατασκευή πρωτεϊνικών μικροσυστοιχιών, βασισμένη στην επιλεκτική πρωτεϊνική προσρόφηση σε υδρόφιλες έναντι υδρόφοβων δομών που δημιουργούνται με επιλεκτική εναπόθεση φθορανθρακικού υμενίου στο πλάσμα.
GR20070100394A 2007-06-20 2007-06-20 Μεθοδος για την κατασκευη μικροσυστοιχιας GR1006042B (el)

Priority Applications (4)

Application Number Priority Date Filing Date Title
GR20070100394A GR1006042B (el) 2007-06-20 2007-06-20 Μεθοδος για την κατασκευη μικροσυστοιχιας
EP08762641.2A EP2173474B1 (en) 2007-06-20 2008-06-20 Method for making a microarray
PCT/GR2008/000048 WO2008155585A1 (en) 2007-06-20 2008-06-20 Method for making a microarray
US12/665,817 US20100248993A1 (en) 2007-06-20 2008-06-20 Method for making a microarray

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GR20070100394A GR1006042B (el) 2007-06-20 2007-06-20 Μεθοδος για την κατασκευη μικροσυστοιχιας

Publications (1)

Publication Number Publication Date
GR1006042B true GR1006042B (el) 2008-09-03

Family

ID=38941943

Family Applications (1)

Application Number Title Priority Date Filing Date
GR20070100394A GR1006042B (el) 2007-06-20 2007-06-20 Μεθοδος για την κατασκευη μικροσυστοιχιας

Country Status (4)

Country Link
US (1) US20100248993A1 (el)
EP (1) EP2173474B1 (el)
GR (1) GR1006042B (el)
WO (1) WO2008155585A1 (el)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20110105366A1 (en) 2007-06-18 2011-05-05 Illumina, Inc. Microfabrication methods for the optimal patterning of substrates
CN102351569B (zh) * 2011-07-08 2013-03-27 中国科学院物理研究所 一种硅表面抗反射纳米阵列结构的制备方法
US8987174B2 (en) * 2011-10-28 2015-03-24 Prognosys Biosciences, Inc. Methods for manufacturing molecular arrays
CN103482564A (zh) * 2013-08-27 2014-01-01 西安交通大学 基于纳米粒子掩膜刻蚀的图形化亲疏复合表面制备工艺
KR101529528B1 (ko) * 2014-01-06 2015-06-18 한국과학기술연구원 저반사성 초소수 또는 초발수 유리 및 그 제조방법
WO2015118843A1 (ja) * 2014-02-04 2015-08-13 パナソニックＩｐマネジメント株式会社 試料検出プレート、これを用いた蛍光検出システム及び蛍光検出方法
GB2535969A (en) * 2014-09-19 2016-09-07 P2I Ltd Solid Phase Synthesis and Products Obtained thereby
CN104357917A (zh) * 2014-09-24 2015-02-18 中国科学院天津工业生物技术研究所 一种用于微阵列生物芯片的载体、其制备方法及微阵列生物芯片
US10300485B2 (en) * 2015-10-23 2019-05-28 The Royal Institution For The Advancement Of Learning/Mcgill University Nanoarray-in-microarray multiplexed analysis methods and systems
CN105776125B (zh) * 2016-03-31 2017-06-09 东南大学 一种楔形图案化超浸润性表面及其制备方法
EP3415230A1 (en) * 2017-06-16 2018-12-19 Danmarks Tekniske Universitet Regulation of droplet size on an element post fabrication
CN113105263A (zh) * 2021-04-09 2021-07-13 电子科技大学 一种具有纳米级亲水位点的超疏水表面的制备方法
WO2024099959A1 (en) * 2022-11-07 2024-05-16 Gnothis Holding Ag Selective-area coated protein resistant surface

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030082587A1 (en) * 2001-12-28 2003-05-01 Michael Seul Arrays of microparticles and methods of preparation thereof
US6565813B1 (en) * 1998-02-04 2003-05-20 Merck & Co., Inc. Virtual wells for use in high throughput screening assays
EP1364702A2 (en) * 2002-05-15 2003-11-26 Samsung Electronics Co., Ltd. Process for producing array plate for biomolecules having hydrophilic and hydrophobic regions
US20050130226A1 (en) * 2003-09-26 2005-06-16 The University Of Cincinnati Fully integrated protein lab-on-a-chip with smart microfluidics for spot array generation

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040235008A1 (en) * 2002-11-14 2004-11-25 Affymetrix, Inc. Methods and compositions for profiling transcriptionally active sites of the genome

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6565813B1 (en) * 1998-02-04 2003-05-20 Merck & Co., Inc. Virtual wells for use in high throughput screening assays
US20030082587A1 (en) * 2001-12-28 2003-05-01 Michael Seul Arrays of microparticles and methods of preparation thereof
EP1364702A2 (en) * 2002-05-15 2003-11-26 Samsung Electronics Co., Ltd. Process for producing array plate for biomolecules having hydrophilic and hydrophobic regions
US20050130226A1 (en) * 2003-09-26 2005-06-16 The University Of Cincinnati Fully integrated protein lab-on-a-chip with smart microfluidics for spot array generation

Also Published As

Publication number Publication date
US20100248993A1 (en) 2010-09-30
EP2173474B1 (en) 2015-08-05
EP2173474A1 (en) 2010-04-14
WO2008155585A1 (en) 2008-12-24

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