GR1001151B - Novel pharmaceutical use - Google Patents

Novel pharmaceutical use

Info

Publication number
GR1001151B
GR1001151B GR900100679A GR900100679A GR1001151B GR 1001151 B GR1001151 B GR 1001151B GR 900100679 A GR900100679 A GR 900100679A GR 900100679 A GR900100679 A GR 900100679A GR 1001151 B GR1001151 B GR 1001151B
Authority
GR
Greece
Prior art keywords
pharmaceutical use
novel pharmaceutical
novel
thioredoxin
malignancies
Prior art date
Application number
GR900100679A
Other languages
Greek (el)
Other versions
GR900100679A (en
Inventor
Anders Rosen
Original Assignee
Astra Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astra Ab filed Critical Astra Ab
Publication of GR900100679A publication Critical patent/GR900100679A/en
Publication of GR1001151B publication Critical patent/GR1001151B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0012—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7)
    • C12N9/0036—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on NADH or NADPH (1.6)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/20—Interleukins [IL]
    • A61K38/2013—IL-2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/44—Oxidoreductases (1)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y108/00—Oxidoreductases acting on sulfur groups as donors (1.8)
    • C12Y108/01—Oxidoreductases acting on sulfur groups as donors (1.8) with NAD+ or NADP+ as acceptor (1.8.1)
    • C12Y108/01008—Protein-disulfide reductase (1.8.1.8), i.e. thioredoxin

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Oncology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Η χρήση θειορεδοξίνης στη θεραπεία Β λεμφοκυτταρικής λευχαιμίας και ορισμένων άλλων κακοηθών νόσων. ωThe use of thioredoxin in the treatment of B lymphocytic leukemia and some other malignancies. ω

GR900100679A 1989-09-12 1990-09-10 Novel pharmaceutical use GR1001151B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE8903003A SE8903003D0 (en) 1989-09-12 1989-09-12 NOVEL MEDICAL USE

Publications (2)

Publication Number Publication Date
GR900100679A GR900100679A (en) 1992-01-20
GR1001151B true GR1001151B (en) 1993-05-24

Family

ID=20376862

Family Applications (1)

Application Number Title Priority Date Filing Date
GR900100679A GR1001151B (en) 1989-09-12 1990-09-10 Novel pharmaceutical use

Country Status (12)

Country Link
EP (1) EP0489113A1 (en)
JP (1) JPH05500216A (en)
AU (1) AU641942B2 (en)
CA (1) CA2065454A1 (en)
DD (1) DD298056A5 (en)
FI (1) FI921058A0 (en)
GR (1) GR1001151B (en)
HU (1) HUT62932A (en)
IE (1) IE903233A1 (en)
PT (1) PT95284A (en)
SE (1) SE8903003D0 (en)
WO (1) WO1991004320A1 (en)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2091684T3 (en) 1992-11-13 1996-11-01 Idec Pharma Corp THERAPEUTIC APPLICATION OF CHEMICAL AND RADIO-MARKED ANTIBODIES AGAINST THE RESTRICTED DIFFERENTIATION ANTIGEN OF HUMAN B-LYMPHOCYTES FOR THE TREATMENT OF B-CELL LYMPHOMA.
US7744877B2 (en) 1992-11-13 2010-06-29 Biogen Idec Inc. Expression and use of anti-CD20 Antibodies
WO1998000160A1 (en) * 1996-06-28 1998-01-08 Nat Jewish Ct Immun & Respirat USE OF THIOREDOXIN-LIKE MOLECULES FOR INDUCTION OF MnSOD TO TREAT OXIDATIVE DAMAGE
US6689775B2 (en) 1999-06-03 2004-02-10 Arizona Board Of Regents, Acting On Behalf Of The University Of Arizona Uses of thioredoxin
CA2274116C (en) * 1996-12-06 2009-05-05 Garth Powis Use, of an inhibitor of thioredoxin, for inhibiting tumor growth
US5919657A (en) * 1997-04-09 1999-07-06 Incyte Pharmaceuticals, Inc. Nucleic acids encoding human thioredoxin protein; related reagents
US7585645B2 (en) 1997-05-27 2009-09-08 Sembiosys Genetics Inc. Thioredoxin and thioredoxin reductase containing oil body based products
EP1049772A1 (en) 1998-01-30 2000-11-08 Genesense Technologies, Inc. Oligonucleotide sequences complementary to thioredoxin or thioredoxin reductase genes and methods of using same to modulate cell growth
DK1974747T3 (en) 1998-08-11 2012-09-17 Biogen Idec Inc Combination therapies for B-cell lymphomas comprising administration of anti-CD20 antibody
PT2055313E (en) 1998-11-09 2015-08-25 Biogen Idec Inc Treatment of hematologic malignancies associated with circulating tumor cells using chimeric anti-cd20 antibody
US8557244B1 (en) 1999-08-11 2013-10-15 Biogen Idec Inc. Treatment of aggressive non-Hodgkins lymphoma with anti-CD20 antibody
EP1332212A2 (en) * 2000-08-25 2003-08-06 Curagen Corporation Proteins and nucleic acids encoding same
WO2004024868A2 (en) 2002-09-10 2004-03-25 National Jewish Medical And Research Center Product and process for liquefaction of mucus or sputum
US9168290B2 (en) 2013-03-15 2015-10-27 Orpro Therapeutics, Inc. Product and process for mucus viscosity normalization

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2633295B2 (en) * 1987-06-12 1997-07-23 味の素株式会社 Gene encoding human ADF

Also Published As

Publication number Publication date
AU6433690A (en) 1991-04-18
WO1991004320A1 (en) 1991-04-04
GR900100679A (en) 1992-01-20
AU641942B2 (en) 1993-10-07
JPH05500216A (en) 1993-01-21
HU9200821D0 (en) 1992-05-28
HUT62932A (en) 1993-06-28
FI921058A0 (en) 1992-03-11
SE8903003D0 (en) 1989-09-12
DD298056A5 (en) 1992-02-06
PT95284A (en) 1991-08-14
CA2065454A1 (en) 1991-03-13
EP0489113A1 (en) 1992-06-10
IE903233A1 (en) 1991-03-27

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