GR1000483B - Μεθοδος παρασκευης διδεοξυινοσινης με ενζυματικη απαμινωση διδεοξυαδενοσινης. - Google Patents

Μεθοδος παρασκευης διδεοξυινοσινης με ενζυματικη απαμινωση διδεοξυαδενοσινης.

Info

Publication number
GR1000483B
GR1000483B GR880100455A GR880100455A GR1000483B GR 1000483 B GR1000483 B GR 1000483B GR 880100455 A GR880100455 A GR 880100455A GR 880100455 A GR880100455 A GR 880100455A GR 1000483 B GR1000483 B GR 1000483B
Authority
GR
Greece
Prior art keywords
desamination
dideoxyadenosine
dideoxyinosine
enzymatic
preparation
Prior art date
Application number
GR880100455A
Other languages
English (en)
Other versions
GR880100455A (en
Inventor
A Daniel Benigni
R Paul Brodfuehrer
Vittorio Farina
Original Assignee
Bristol Myers Scuibb Company
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Scuibb Company filed Critical Bristol Myers Scuibb Company
Publication of GR880100455A publication Critical patent/GR880100455A/el
Publication of GR1000483B publication Critical patent/GR1000483B/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/26—Preparation of nitrogen-containing carbohydrates
    • C12P19/28—N-glycosides
    • C12P19/30—Nucleotides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/26—Preparation of nitrogen-containing carbohydrates
    • C12P19/28—N-glycosides
    • C12P19/38—Nucleosides
    • C12P19/40—Nucleosides having a condensed ring system containing a six-membered ring having two nitrogen atoms in the same ring, e.g. purine nucleosides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Saccharide Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Αποκαλύπτεται νέα μέθοδος για να παράγεται εκλεκτικά β-2, 3-διδεοξυϊνοσίνη σε υψηλές αποδόσεις. Η β-2, 3- διδεοξυϊνοσίνη που παράγεται με τον τρόπο αυτό είναι χρήσιμη σαν αντιϊογενής και αντιβιοτικός παράγων. ω
GR880100455A 1987-07-17 1988-07-08 Μεθοδος παρασκευης διδεοξυινοσινης με ενζυματικη απαμινωση διδεοξυαδενοσινης. GR1000483B (el)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US7484487A 1987-07-17 1987-07-17

Publications (2)

Publication Number Publication Date
GR880100455A GR880100455A (en) 1989-04-12
GR1000483B true GR1000483B (el) 1992-07-30

Family

ID=22122017

Family Applications (1)

Application Number Title Priority Date Filing Date
GR880100455A GR1000483B (el) 1987-07-17 1988-07-08 Μεθοδος παρασκευης διδεοξυινοσινης με ενζυματικη απαμινωση διδεοξυαδενοσινης.

Country Status (8)

Country Link
KR (1) KR930005870B1 (el)
AT (1) AT395977B (el)
CA (1) CA1335187C (el)
ES (1) ES2007532A6 (el)
FI (1) FI92602C (el)
GR (1) GR1000483B (el)
LU (1) LU87280A1 (el)
PT (1) PT88017B (el)

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH07116042B2 (ja) * 1985-05-15 1995-12-13 ザ ウエルカム フアウンデ−シヨン リミテツド ヌクレオシド化合物
EP0285884A3 (en) * 1987-03-20 1990-07-04 Bristol-Myers Squibb Company process to produce 2', 3'-dideoxynucleosides

Also Published As

Publication number Publication date
ATA173088A (de) 1992-09-15
FI92602B (fi) 1994-08-31
CA1335187C (en) 1995-04-11
KR900001858A (ko) 1990-02-27
KR930005870B1 (ko) 1993-06-25
GR880100455A (en) 1989-04-12
FI883339A (fi) 1989-01-18
FI92602C (fi) 1994-12-12
LU87280A1 (fr) 1989-03-08
ES2007532A6 (es) 1989-06-16
PT88017A (pt) 1989-06-30
AT395977B (de) 1993-04-26
PT88017B (pt) 1995-03-01
FI883339A0 (fi) 1988-07-13

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