GR1000466B - Μεθοδος παρασκευης νεων φαρμακευτικων μορφων κυκλοσπορινης. - Google Patents
Μεθοδος παρασκευης νεων φαρμακευτικων μορφων κυκλοσπορινης.Info
- Publication number
- GR1000466B GR1000466B GR900100076A GR900100076A GR1000466B GR 1000466 B GR1000466 B GR 1000466B GR 900100076 A GR900100076 A GR 900100076A GR 900100076 A GR900100076 A GR 900100076A GR 1000466 B GR1000466 B GR 1000466B
- Authority
- GR
- Greece
- Prior art keywords
- cyclosporine
- preparation
- pharmaceutical forms
- novel pharmaceutical
- alkylene
- Prior art date
Links
- PMATZTZNYRCHOR-CGLBZJNRSA-N Cyclosporin A Chemical compound CC[C@@H]1NC(=O)[C@H]([C@H](O)[C@H](C)C\C=C\C)N(C)C(=O)[C@H](C(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](C(C)C)NC(=O)[C@H](CC(C)C)N(C)C(=O)CN(C)C1=O PMATZTZNYRCHOR-CGLBZJNRSA-N 0.000 title abstract 2
- 108010036949 Cyclosporine Proteins 0.000 title abstract 2
- 229960001265 ciclosporin Drugs 0.000 title abstract 2
- 229930182912 cyclosporin Natural products 0.000 title abstract 2
- 238000002360 preparation method Methods 0.000 title 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 4
- -1 fatty acid saccharide Chemical class 0.000 abstract 4
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 abstract 2
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 abstract 2
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 abstract 2
- 229920005862 polyol Polymers 0.000 abstract 2
- 239000004480 active ingredient Substances 0.000 abstract 1
- 125000002947 alkylene group Chemical group 0.000 abstract 1
- 235000014113 dietary fatty acids Nutrition 0.000 abstract 1
- 239000003085 diluting agent Substances 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- LYCAIKOWRPUZTN-UHFFFAOYSA-N ethylene glycol Natural products OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 abstract 1
- 229930195729 fatty acid Natural products 0.000 abstract 1
- 239000000194 fatty acid Substances 0.000 abstract 1
- 235000011187 glycerol Nutrition 0.000 abstract 1
- WGCNASOHLSPBMP-UHFFFAOYSA-N hydroxyacetaldehyde Natural products OCC=O WGCNASOHLSPBMP-UHFFFAOYSA-N 0.000 abstract 1
- 239000007788 liquid Substances 0.000 abstract 1
- 229940057995 liquid paraffin Drugs 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 229920001515 polyalkylene glycol Polymers 0.000 abstract 1
- 229920000642 polymer Polymers 0.000 abstract 1
- 150000003077 polyols Chemical class 0.000 abstract 1
Landscapes
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
Abstract
Φαρμακευτικές συνθέσεις οι οποίες περιλαμβάνουν (α) μια κυκλοσπορίνη ως δραστικό συστατικό (β) ένα μονοεστέρα σακχαρίτου λιπαρού οξέος και (γ) ένα αραιωτικό μέσο ή ένα φορέα. Τα συστατικά (γ) συνήθως είναι αιθανόλη, μια αλκυλενογλυκόλη (π.χ. 1,2-προπυλενογλυκόλη), μια αλκυλενοπολυόλη (π.χ. γλυκερίνη), μια πολυαλκυλενογλυκόλη (π.χ. FEG), ένας αλκυλενοπολυολοαιθήρ ή εστήρ (π.χ. προϊόν GELUCIR), υπερυγρά ή υπογρά παραφφίνη ένα πολυμερές οξειδίου οργανοσιλικόνης, ενώ ολιγώτερο προτιμάται η αιθανόλη.ω
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB898901898A GB8901898D0 (en) | 1989-01-28 | 1989-01-28 | Cane protection caps |
| GB898902898A GB8902898D0 (en) | 1989-02-09 | 1989-02-09 | Improvements in or relating to organic compounds |
| GB898902901A GB8902901D0 (en) | 1989-02-09 | 1989-02-09 | Improvements in or relating to organic compounds |
| GB898903147A GB8903147D0 (en) | 1989-02-13 | 1989-02-13 | Improvements in or relating to organic compounds |
| GB898903663A GB8903663D0 (en) | 1989-02-17 | 1989-02-17 | Improvements in or relating to organic compounds |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| GR900100076A GR900100076A (en) | 1991-06-28 |
| GR1000466B true GR1000466B (el) | 1992-07-30 |
Family
ID=27516885
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GR900100076A GR1000466B (el) | 1989-01-28 | 1990-02-07 | Μεθοδος παρασκευης νεων φαρμακευτικων μορφων κυκλοσπορινης. |
Country Status (1)
| Country | Link |
|---|---|
| GR (1) | GR1000466B (el) |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FI65914C (fi) * | 1978-03-07 | 1984-08-10 | Sandoz Ag | Foerfarande foer framstaellning av farmaceutiska kompositionerinnehaollande cyklosporin a |
| NL8600050A (nl) * | 1986-01-13 | 1987-08-03 | Sanico Nv | Farmaceutisch preparaat met vertraagde afgifte van het werkzame bestanddeel en werkwijze voor de bereiding er van. |
| HU205010B (en) * | 1987-09-15 | 1992-03-30 | Sandoz Ag | Process for producing pharmaceutical compositions comprising compounds soluble up to 1 per cent and having medical activity |
| KR0148748B1 (ko) * | 1988-09-16 | 1998-08-17 | 장 크라메르, 한스 루돌프 하우스 | 사이클로스포린을 함유하는 약학조성물 |
-
1990
- 1990-02-07 GR GR900100076A patent/GR1000466B/el not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| GR900100076A (en) | 1991-06-28 |
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Legal Events
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| MA | Right expired |