GB996253A - Substituted hydrazides - Google Patents
Substituted hydrazidesInfo
- Publication number
- GB996253A GB996253A GB31605/63A GB3160563A GB996253A GB 996253 A GB996253 A GB 996253A GB 31605/63 A GB31605/63 A GB 31605/63A GB 3160563 A GB3160563 A GB 3160563A GB 996253 A GB996253 A GB 996253A
- Authority
- GB
- United Kingdom
- Prior art keywords
- inhibiting
- thioxanthenyl
- chlorobenzhydryl
- benzhydryl
- radical
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/22—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with hetero atoms directly attached to ring nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/22—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with hetero atoms directly attached to ring nitrogen atoms
- C07D295/28—Nitrogen atoms
- C07D295/32—Nitrogen atoms acylated with carboxylic or carbonic acids, or their nitrogen or sulfur analogues
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/78—Ring systems having three or more relevant rings
- C07D311/80—Dibenzopyrans; Hydrogenated dibenzopyrans
- C07D311/82—Xanthenes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2603/00—Systems containing at least three condensed rings
- C07C2603/02—Ortho- or ortho- and peri-condensed systems
- C07C2603/04—Ortho- or ortho- and peri-condensed systems containing three rings
- C07C2603/06—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members
- C07C2603/10—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members containing five-membered rings
- C07C2603/12—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members containing five-membered rings only one five-membered ring
- C07C2603/18—Fluorenes; Hydrogenated fluorenes
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
The invention comprises compounds of formula <FORM:0996253/C2/1> wherein Ar2CH is a benzhydryl, ar-chlorobenzhydryl, 9-fluorenyl, 9,10-dihydro-9-anthryl, 9-xanthenyl, 9-thioxanthenyl or chloro-9-thioxanthenyl radical and Z is an alkyl, hydroxyalkyl, benzyl, ar-methylbenzene, ar-methoxybenzyl, ar-halobenzyl, benzhydryl or ar-chlorobenzhydryl radical, the alkyl groups in Z having up to 6 carbon atoms, non-toxic acid addition salts thereof, and their preparation by reacting the appropriate acid chloride or bromide with a 4 - substituted - 1 - amino - piperazine in an inert solvent, followed by hydrolysis of any esterified hydroxyalkyl group Z. The compounds of the invention have appetite-inhibiting, pepsin-inhibiting, anti-ulcer, diuretic, anti-algal and germination-inhibiting activity.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US21885062A | 1962-08-23 | 1962-08-23 |
Publications (1)
Publication Number | Publication Date |
---|---|
GB996253A true GB996253A (en) | 1965-06-23 |
Family
ID=22816747
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB31605/63A Expired GB996253A (en) | 1962-08-23 | 1963-08-09 | Substituted hydrazides |
Country Status (4)
Country | Link |
---|---|
BE (1) | BE636430A (en) |
BR (1) | BR6352174D0 (en) |
FR (1) | FR3365M (en) |
GB (1) | GB996253A (en) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5250528A (en) * | 1989-08-02 | 1993-10-05 | Fujisawa Pharmaceutical Co., Ltd. | New aminopiperazine derivatives |
EP1043320A1 (en) * | 1997-10-09 | 2000-10-11 | Fujisawa Pharmaceutical Co., Ltd. | New process for producing aminopiperazine derivatives |
-
0
- BE BE636430D patent/BE636430A/xx unknown
-
1963
- 1963-08-09 GB GB31605/63A patent/GB996253A/en not_active Expired
- 1963-08-21 FR FR945262A patent/FR3365M/en active Active
- 1963-08-22 BR BR152174/63A patent/BR6352174D0/en unknown
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5250528A (en) * | 1989-08-02 | 1993-10-05 | Fujisawa Pharmaceutical Co., Ltd. | New aminopiperazine derivatives |
EP1043320A1 (en) * | 1997-10-09 | 2000-10-11 | Fujisawa Pharmaceutical Co., Ltd. | New process for producing aminopiperazine derivatives |
EP1043320A4 (en) * | 1997-10-09 | 2000-12-06 | Fujisawa Pharmaceutical Co | New process for producing aminopiperazine derivatives |
Also Published As
Publication number | Publication date |
---|---|
BR6352174D0 (en) | 1973-07-17 |
FR3365M (en) | 1965-06-08 |
BE636430A (en) |
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