GB995367A - New benzofuran derivatives and method of preparing the same - Google Patents

New benzofuran derivatives and method of preparing the same

Info

Publication number
GB995367A
GB995367A GB41643/62A GB4164362A GB995367A GB 995367 A GB995367 A GB 995367A GB 41643/62 A GB41643/62 A GB 41643/62A GB 4164362 A GB4164362 A GB 4164362A GB 995367 A GB995367 A GB 995367A
Authority
GB
United Kingdom
Prior art keywords
methyl
hydrogen
preparing
same
benzofuran derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB41643/62A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Societe Belge de lAzote et des Produits Chimiques du Marly SA
Original Assignee
Societe Belge de lAzote et des Produits Chimiques du Marly SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Societe Belge de lAzote et des Produits Chimiques du Marly SA filed Critical Societe Belge de lAzote et des Produits Chimiques du Marly SA
Publication of GB995367A publication Critical patent/GB995367A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • C07D307/80—Radicals substituted by oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The invention comprises compounds of the general formula <FORM:0995367/C2/1> wherein R1 is alkyl (1-6C), R2 is hydrogen or methyl, R3 and R4 are methyl, ethyl or propyl, or join in a piperidino, pyrrolidino or morpholino group, and Y is hydrogen, iodine or bromine; and their pharmaceutically acceptable acid addition salts; and their preparation by reacting an alkali metal salt of a corresponding 3 - (p - hydroxy - benzoyl) - benzofuran with a compound X-CHR2-CH2-NR3R4 where X is a halogen atom in a solvent immiscible with water. Pharmaceutical compositions comprises compounds and salts of the invention with diluents and excipients. Forms for oral (tablets) and parenteral (solution) administration are mentioned. The compounds act on the vascular system.
GB41643/62A 1961-11-24 1962-11-02 New benzofuran derivatives and method of preparing the same Expired GB995367A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DES76824A DE1246755B (en) 1961-11-24 1961-11-24 Process for the preparation of substituted coumarones

Publications (1)

Publication Number Publication Date
GB995367A true GB995367A (en) 1965-06-16

Family

ID=7506391

Family Applications (1)

Application Number Title Priority Date Filing Date
GB41643/62A Expired GB995367A (en) 1961-11-24 1962-11-02 New benzofuran derivatives and method of preparing the same

Country Status (10)

Country Link
AT (1) AT241447B (en)
BE (1) BE625039A (en)
BR (1) BR6243846D0 (en)
CH (1) CH415677A (en)
DE (1) DE1246755B (en)
FR (1) FR1339389A (en)
GB (1) GB995367A (en)
NL (1) NL284505A (en)
OA (1) OA01076A (en)
SE (1) SE311166B (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2583754B1 (en) * 1985-06-25 1987-10-23 Sanofi Sa MOLECULAR COMPLEXES FORMED FROM A BENZOFURAN DERIVATIVE AND ALUMINUM CHLORIDE, THEIR PREPARATION AND THEIR USE

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1080114B (en) * 1956-12-21 1960-04-21 Lab Labaz Soc D Process for the preparation of substituted coumarones

Also Published As

Publication number Publication date
DE1246755C2 (en) 1968-05-30
DE1246755B (en) 1967-08-10
SE311166B (en) 1969-06-02
OA01076A (en) 1968-08-07
BR6243846D0 (en) 1973-05-24
CH415677A (en) 1966-06-30
AT241447B (en) 1965-07-26
BE625039A (en) 1963-05-20
NL284505A (en)
FR1339389A (en) 1963-10-04

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