GB9919411D0 - Chemical compounds - Google Patents
Chemical compoundsInfo
- Publication number
- GB9919411D0 GB9919411D0 GBGB9919411.0A GB9919411A GB9919411D0 GB 9919411 D0 GB9919411 D0 GB 9919411D0 GB 9919411 A GB9919411 A GB 9919411A GB 9919411 D0 GB9919411 D0 GB 9919411D0
- Authority
- GB
- United Kingdom
- Prior art keywords
- chemical compounds
- compounds
- chemical
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
- C07D215/22—Oxygen atoms attached in position 2 or 4
- C07D215/227—Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
- A61K31/404—Indoles, e.g. pindolol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4704—2-Quinolinones, e.g. carbostyril
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/08—Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
Priority Applications (14)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB9919411.0A GB9919411D0 (en) | 1999-08-18 | 1999-08-18 | Chemical compounds |
IL14782100A IL147821A0 (en) | 1999-08-18 | 2000-08-14 | Benzoic acid derivatives and their use as ppar receptor agonists |
EP00953320A EP1210343A2 (en) | 1999-08-18 | 2000-08-14 | Benzoic acid derivatives and their use as ppar receptor agonists |
KR1020027002019A KR20020020817A (en) | 1999-08-18 | 2000-08-14 | Chemical Compounds |
AU65834/00A AU6583400A (en) | 1999-08-18 | 2000-08-14 | Chemical compounds |
JP2001516533A JP2003507327A (en) | 1999-08-18 | 2000-08-14 | Chemical compound |
CN00814336A CN1379774A (en) | 1999-08-18 | 2000-08-14 | Compounds |
BR0013368-0A BR0013368A (en) | 1999-08-18 | 2000-08-14 | Use of a compound, compound, and pharmaceutical composition |
NZ517059A NZ517059A (en) | 1999-08-18 | 2000-08-14 | Indole derivatives of benzoic acid which act as peroxisome proliferator activated receptor (PPAR) |
PCT/GB2000/003140 WO2001012187A2 (en) | 1999-08-18 | 2000-08-14 | Benzoic acid derivatives and their use as ppar receptor agonists |
CA002380775A CA2380775A1 (en) | 1999-08-18 | 2000-08-14 | Benzoic acid derivatives and their use as ppar receptor agonists |
MXPA02001598A MXPA02001598A (en) | 1999-08-18 | 2000-08-14 | Chemical compounds. |
ZA200200669A ZA200200669B (en) | 1999-08-18 | 2002-01-24 | Benzoic acid derivatives and their use as PPAR receptor agonists. |
NO20020765A NO20020765L (en) | 1999-08-18 | 2002-02-15 | Chemical connections |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB9919411.0A GB9919411D0 (en) | 1999-08-18 | 1999-08-18 | Chemical compounds |
Publications (1)
Publication Number | Publication Date |
---|---|
GB9919411D0 true GB9919411D0 (en) | 1999-10-20 |
Family
ID=10859283
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GBGB9919411.0A Ceased GB9919411D0 (en) | 1999-08-18 | 1999-08-18 | Chemical compounds |
Country Status (14)
Country | Link |
---|---|
EP (1) | EP1210343A2 (en) |
JP (1) | JP2003507327A (en) |
KR (1) | KR20020020817A (en) |
CN (1) | CN1379774A (en) |
AU (1) | AU6583400A (en) |
BR (1) | BR0013368A (en) |
CA (1) | CA2380775A1 (en) |
GB (1) | GB9919411D0 (en) |
IL (1) | IL147821A0 (en) |
MX (1) | MXPA02001598A (en) |
NO (1) | NO20020765L (en) |
NZ (1) | NZ517059A (en) |
WO (1) | WO2001012187A2 (en) |
ZA (1) | ZA200200669B (en) |
Families Citing this family (60)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6495949B1 (en) | 1999-11-03 | 2002-12-17 | Orion Electric Co., Ltd. | Electron tube cathode |
US6503907B2 (en) * | 2000-11-28 | 2003-01-07 | Hoffmann-La Roche Inc. | Indole and dihydroindole derivatives |
EP1911462A3 (en) | 2001-01-26 | 2011-11-30 | Schering Corporation | Compositions comprising a sterol absorption inhibitor |
US7291639B2 (en) | 2001-06-20 | 2007-11-06 | Wyeth | Aryloxy-acetic acid compounds useful as inhibitors of plasminogen activator inhibitor-1 (PAI-1) |
TWI224101B (en) | 2001-06-20 | 2004-11-21 | Wyeth Corp | Substituted naphthyl indole derivatives as inhibitors of plasminogen activator inhibitor type-1 (PAI-1) |
ES2290318T3 (en) | 2001-06-20 | 2008-02-16 | Wyeth | REPLACED DERIVATIVES OF INDOLIC ACID AS INHIBITORS OF THE INHIBITOR OF THE PLASMINOGEN-1 ACTIVATOR (PAI-1). |
WO2003035602A1 (en) * | 2001-10-25 | 2003-05-01 | Sankyo Company, Limited | Lipid modulators |
WO2003066581A1 (en) * | 2002-02-05 | 2003-08-14 | Eli Lilly And Company | Urea linker derivatives for use as ppar modulators |
US7355069B2 (en) | 2002-06-20 | 2008-04-08 | Astrazeneca Ab | Ortho-substituted benzoic acid derivatives for the treatment of insulin resistance |
SE0201937D0 (en) | 2002-06-20 | 2002-06-20 | Astrazeneca Ab | Therapeutic agents |
CA2509170A1 (en) | 2002-12-10 | 2004-06-24 | Wyeth | Substituted 3-alkyl and 3-arylalkyl 1h-indol-1-yl acetic acid derivatives as inhibitors of plasminogen activator inhibitor-1 (pai-1) |
UA80453C2 (en) | 2002-12-10 | 2007-09-25 | Derivatives of substituted dyhydropyranoindol-3,4-dion as inhibitors of plasminogen activator inhibitor-1 (pai-1) | |
JP2006510673A (en) | 2002-12-10 | 2006-03-30 | ワイス | Aryl, aryloxy and alkyloxy substituted 1H-indol-3-ylglyoxylic acid derivatives as inhibitors of plasminogen activator inhibitor 1 (PAI-1) |
CN1726190A (en) | 2002-12-10 | 2006-01-25 | 惠氏公司 | Substituted 3-carbonyl-1h-indol-1-yl acetic acid derivatives as inhibitors of plasminogen activator inhibitor-1 (PAI-1) |
CN1726191A (en) | 2002-12-10 | 2006-01-25 | 惠氏公司 | Substituted indole oxo-acetyl amino acetic acid derivatives as inhibitors of plasminogen activator inhibitor-1 (PAI-1) |
DE10308352A1 (en) * | 2003-02-27 | 2004-09-09 | Aventis Pharma Deutschland Gmbh | Branched side chain arylcycloalkyl derivatives, process for their preparation and their use as medicaments |
TWI289141B (en) | 2003-03-11 | 2007-11-01 | Hoffmann La Roche F. Ag. | Quinolinone derivatives and uses thereof |
US7129264B2 (en) | 2003-04-16 | 2006-10-31 | Bristol-Myers Squibb Company | Biarylmethyl indolines and indoles as antithromboembolic agents |
US20060264496A1 (en) * | 2003-04-25 | 2006-11-23 | H. Lundbeck A/S | Substituted indoline and indole derivatives |
JP4895811B2 (en) | 2003-09-11 | 2012-03-14 | ケミア,インコーポレイテッド | Cytokine inhibitor |
US7163954B2 (en) | 2003-09-25 | 2007-01-16 | Wyeth | Substituted naphthyl benzothiophene acids |
US7442805B2 (en) | 2003-09-25 | 2008-10-28 | Wyeth | Substituted sulfonamide-indoles |
US7268159B2 (en) | 2003-09-25 | 2007-09-11 | Wyeth | Substituted indoles |
US7351726B2 (en) | 2003-09-25 | 2008-04-01 | Wyeth | Substituted oxadiazolidinediones |
US7411083B2 (en) | 2003-09-25 | 2008-08-12 | Wyeth | Substituted acetic acid derivatives |
US7446201B2 (en) | 2003-09-25 | 2008-11-04 | Wyeth | Substituted heteroaryl benzofuran acids |
US7582773B2 (en) | 2003-09-25 | 2009-09-01 | Wyeth | Substituted phenyl indoles |
CN101039936A (en) | 2004-08-23 | 2007-09-19 | 惠氏公司 | Oxazolo-naphthyl acids as plasminogen activator inhibitor type-1(pai-1) modulators useful in the treatment of thrombosis and cardiovascular diseases |
ATE399156T1 (en) * | 2004-10-27 | 2008-07-15 | Hoffmann La Roche | NEW INDOLE OR BENZIMIDAZOLE DERIVATIVES |
DE602006018447D1 (en) * | 2005-04-13 | 2011-01-05 | Neuraxon Inc | SUBSTITUTED INDOL COMPOUNDS WITH NOS-HEMDERING ACTIVITY |
WO2007022321A2 (en) | 2005-08-17 | 2007-02-22 | Wyeth | Substituted indoles and use thereof |
EP1917245A1 (en) | 2005-08-21 | 2008-05-07 | Abbott GmbH & Co. KG | Heterocyclic compounds and their use as binding partners for 5-ht5 receptors |
JP5350219B2 (en) | 2006-04-13 | 2013-11-27 | ニューラクソン,インコーポレーテッド | 1,5 and 3,6-substituted indole compounds having NOS inhibitory activity |
JP2009536954A (en) | 2006-05-11 | 2009-10-22 | ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ | 3,4-Dihydro-2H-benzo [1,4] oxazine and thiazine derivatives as CETP inhibitors |
JP2009536953A (en) | 2006-05-11 | 2009-10-22 | ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ | 1,2,3,4-Tetrahydro-quinoline derivatives as CETP inhibitors |
US7432255B2 (en) * | 2006-05-16 | 2008-10-07 | Hoffmann-La Roche Inc. | 1H-indol-5-yl-piperazin-1-yl-methanone derivatives |
WO2008020302A2 (en) * | 2006-08-17 | 2008-02-21 | Pfizer Products Inc. | Heteroaromatic quinoline-based compounds as phosphodiesterase (pde) inhibitors |
CN101668746A (en) | 2007-03-01 | 2010-03-10 | 詹森药业有限公司 | As histamine H 3The tetrahydro isoquinoline compound of receptor modulators |
US8093265B2 (en) | 2007-03-09 | 2012-01-10 | Renovis, Inc. | Bicycloheteroaryl compounds as P2X7 modulators and uses thereof |
MX2009013946A (en) * | 2007-07-02 | 2010-03-10 | Glaxosmithkline Llc | Farnesoid x receptor agonists. |
FR2921366B1 (en) * | 2007-09-26 | 2009-12-04 | Servier Lab | NOVEL HETEROCYCLIC DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME |
MX356032B (en) | 2007-11-16 | 2018-04-11 | Neuraxon Inc | Indole compounds and methods for treating visceral pain. |
EP2250162B1 (en) * | 2008-02-07 | 2014-03-19 | AbbVie Inc. | Amide derivatives as positive allosteric modulators and methods of use thereof |
WO2012027331A1 (en) | 2010-08-27 | 2012-03-01 | Ironwood Pharmaceuticals, Inc. | Compositions and methods for treating or preventing metabolic syndrome and related diseases and disorders |
CN103228270B (en) | 2010-11-08 | 2016-02-10 | 阿尔比里奥公司 | Containing the drug regimen of ibat inhibitor and bile acid binding agent |
MX338535B (en) | 2010-11-08 | 2016-04-21 | Albireo Ab | Ibat inhibitors for the treatment of liver diseases. |
US9051265B2 (en) * | 2011-06-06 | 2015-06-09 | The Scripps Research Institute | N-benzylindole modulators of PPARG |
WO2012170554A1 (en) | 2011-06-06 | 2012-12-13 | Theodore Mark Kamenecka | N-biphenylmethylindole modulators of pparg |
US20140315881A1 (en) * | 2011-07-29 | 2014-10-23 | Tempero Pharmaceuticals, Inc. | Compounds and methods |
US9309227B2 (en) | 2011-11-22 | 2016-04-12 | The Scripps Research Institute | N-biphenylmethylbenzimidazole modulators of PPARG |
US9567328B2 (en) * | 2011-12-21 | 2017-02-14 | Allergan, Inc. | Compounds acting at multiple prostaglandin receptors giving a general anti-inflammatory response |
US9321750B2 (en) | 2012-04-20 | 2016-04-26 | Innov17 Llc | ROR modulators and their uses |
US9708268B2 (en) | 2012-04-30 | 2017-07-18 | Innov17 Llc | ROR modulators and their uses |
CN104788358A (en) * | 2014-01-20 | 2015-07-22 | 中国科学院上海药物研究所 | N-(3-fluoro-4-chlorobenzyl)indole derivative and use thereof |
KR101585605B1 (en) * | 2014-03-20 | 2016-01-21 | 현대약품 주식회사 | Compounds that binding with PPARG(Peroxisome Proliferator Activated Receptor-Gamma) but not act as an agonist and pharmaceutical composition for diseases related with PPARG containing the same as an active ingredient |
WO2015161108A1 (en) | 2014-04-16 | 2015-10-22 | The Scripps Research Institute | Pparg modulators for treatment of osteoporosis |
CN107176914B (en) * | 2016-03-09 | 2022-06-28 | 浙江旭晨医药科技有限公司 | GVS series compound and its use |
EP3632910A4 (en) * | 2017-05-26 | 2021-02-24 | CSPC Zhongqi Pharmaceutical Technology (Shijiazhuang) Co., Ltd. | Lactam compound as fxr receptor agonist |
KR102242658B1 (en) * | 2018-08-29 | 2021-04-21 | 숙명여자대학교산학협력단 | A substituted indole derivatives, preparation method therof and pharmaceutical composition for use in preventing or treating PPARα, PPARγ and PPARδ related diseases containing the same as an active ingredient |
CN112654619B (en) * | 2018-09-07 | 2022-08-30 | 南京明德新药研发有限公司 | Tricyclic furan substituted piperidine diketone compound |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB8524157D0 (en) * | 1984-10-19 | 1985-11-06 | Ici America Inc | Heterocyclic amides |
US4894386A (en) * | 1987-04-15 | 1990-01-16 | Ici Americas Inc. | Aliphatic carboxamides |
US5902726A (en) * | 1994-12-23 | 1999-05-11 | Glaxo Wellcome Inc. | Activators of the nuclear orphan receptor peroxisome proliferator-activated receptor gamma |
ES2108641B1 (en) * | 1995-07-31 | 1998-08-16 | Menarini Lab | QUINOLONIC SULFONIMIDES WITH ANTAGONIST ACTION OF THE LEUCOTRENEES. |
JPH09176162A (en) * | 1995-12-22 | 1997-07-08 | Toubishi Yakuhin Kogyo Kk | Thiazolidinedione derivative, its production and medicinal composition containing the same |
AU7237998A (en) * | 1997-05-16 | 1998-12-08 | Chugai Seiyaku Kabushiki Kaisha | Indole derivatives and mono- and diazaindole derivatives |
-
1999
- 1999-08-18 GB GBGB9919411.0A patent/GB9919411D0/en not_active Ceased
-
2000
- 2000-08-14 NZ NZ517059A patent/NZ517059A/en unknown
- 2000-08-14 IL IL14782100A patent/IL147821A0/en unknown
- 2000-08-14 AU AU65834/00A patent/AU6583400A/en not_active Abandoned
- 2000-08-14 EP EP00953320A patent/EP1210343A2/en not_active Withdrawn
- 2000-08-14 CA CA002380775A patent/CA2380775A1/en not_active Abandoned
- 2000-08-14 JP JP2001516533A patent/JP2003507327A/en active Pending
- 2000-08-14 BR BR0013368-0A patent/BR0013368A/en not_active IP Right Cessation
- 2000-08-14 KR KR1020027002019A patent/KR20020020817A/en not_active Application Discontinuation
- 2000-08-14 MX MXPA02001598A patent/MXPA02001598A/en unknown
- 2000-08-14 CN CN00814336A patent/CN1379774A/en active Pending
- 2000-08-14 WO PCT/GB2000/003140 patent/WO2001012187A2/en active IP Right Grant
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2002
- 2002-01-24 ZA ZA200200669A patent/ZA200200669B/en unknown
- 2002-02-15 NO NO20020765A patent/NO20020765L/en not_active Application Discontinuation
Also Published As
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NZ517059A (en) | 2004-05-28 |
WO2001012187A2 (en) | 2001-02-22 |
IL147821A0 (en) | 2002-08-14 |
BR0013368A (en) | 2002-05-07 |
CA2380775A1 (en) | 2001-02-22 |
KR20020020817A (en) | 2002-03-15 |
WO2001012187A3 (en) | 2001-06-07 |
AU6583400A (en) | 2001-03-13 |
JP2003507327A (en) | 2003-02-25 |
EP1210343A2 (en) | 2002-06-05 |
MXPA02001598A (en) | 2002-07-02 |
NO20020765L (en) | 2002-04-17 |
ZA200200669B (en) | 2003-06-25 |
NO20020765D0 (en) | 2002-02-15 |
CN1379774A (en) | 2002-11-13 |
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