GB9918912D0 - New stilbenes with vascular damaging activity - Google Patents

New stilbenes with vascular damaging activity

Info

Publication number
GB9918912D0
GB9918912D0 GBGB9918912.8A GB9918912A GB9918912D0 GB 9918912 D0 GB9918912 D0 GB 9918912D0 GB 9918912 A GB9918912 A GB 9918912A GB 9918912 D0 GB9918912 D0 GB 9918912D0
Authority
GB
United Kingdom
Prior art keywords
stilbenes
new
vascular damaging
damaging activity
activity
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
GBGB9918912.8A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Angiogene Pharmaceuticals Ltd
Original Assignee
Angiogene Pharmaceuticals Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Angiogene Pharmaceuticals Ltd filed Critical Angiogene Pharmaceuticals Ltd
Priority to GBGB9918912.8A priority Critical patent/GB9918912D0/en
Publication of GB9918912D0 publication Critical patent/GB9918912D0/en
Priority to CA002379544A priority patent/CA2379544A1/en
Priority to EP00951727A priority patent/EP1206429A2/en
Priority to NZ517069A priority patent/NZ517069A/en
Priority to PCT/GB2000/003067 priority patent/WO2001012579A2/en
Priority to JP2001516880A priority patent/JP2003507356A/en
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C43/00—Ethers; Compounds having groups, groups or groups
    • C07C43/02—Ethers
    • C07C43/20—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring
    • C07C43/23—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring containing hydroxy or O-metal groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/52—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an inorganic compound, e.g. an inorganic ion that is complexed with the active ingredient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/06—Phosphorus compounds without P—C bonds
    • C07F9/08—Esters of oxyacids of phosphorus
    • C07F9/09—Esters of phosphoric acids
    • C07F9/12—Esters of phosphoric acids with hydroxyaryl compounds

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Inorganic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
GBGB9918912.8A 1999-08-12 1999-08-12 New stilbenes with vascular damaging activity Ceased GB9918912D0 (en)

Priority Applications (6)

Application Number Priority Date Filing Date Title
GBGB9918912.8A GB9918912D0 (en) 1999-08-12 1999-08-12 New stilbenes with vascular damaging activity
CA002379544A CA2379544A1 (en) 1999-08-12 2000-08-09 New stilbenes with vascular damaging activity
EP00951727A EP1206429A2 (en) 1999-08-12 2000-08-09 Stilbenes with vascular damaging activity
NZ517069A NZ517069A (en) 1999-08-12 2000-08-09 New stilbenes with vascular damaging activity
PCT/GB2000/003067 WO2001012579A2 (en) 1999-08-12 2000-08-09 New stilbenes with vascular damaging activity
JP2001516880A JP2003507356A (en) 1999-08-12 2000-08-09 New stilbenes with vascular damage activity

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB9918912.8A GB9918912D0 (en) 1999-08-12 1999-08-12 New stilbenes with vascular damaging activity

Publications (1)

Publication Number Publication Date
GB9918912D0 true GB9918912D0 (en) 1999-10-13

Family

ID=10858950

Family Applications (1)

Application Number Title Priority Date Filing Date
GBGB9918912.8A Ceased GB9918912D0 (en) 1999-08-12 1999-08-12 New stilbenes with vascular damaging activity

Country Status (6)

Country Link
EP (1) EP1206429A2 (en)
JP (1) JP2003507356A (en)
CA (1) CA2379544A1 (en)
GB (1) GB9918912D0 (en)
NZ (1) NZ517069A (en)
WO (1) WO2001012579A2 (en)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69931766T2 (en) * 1998-04-03 2007-05-31 Ajinomoto Co., Inc. ANTITUMORAL AGENTS
GB0019944D0 (en) * 2000-08-15 2000-09-27 Angiogene Pharm Ltd Compositions with vascular damaging activity
CA2432640A1 (en) 2000-12-21 2002-06-27 Cancer Research Technology Limited Substituted stilbenes, their reactions and anticancer activity
FR2838437B1 (en) 2002-04-11 2004-06-04 Aventis Pharma Sa PROCESSES FOR THE PREPARATION OF COMBRETASTATINS
GB0306908D0 (en) * 2003-03-26 2003-04-30 Angiogene Pharm Ltd Bioreductively activated stilbene prodrugs
EP1631540A4 (en) * 2003-12-16 2006-10-04 Gtx Inc Prodrugs of selective androgen receptor modulators and methods of use thereof
CN1723884A (en) 2004-07-21 2006-01-25 中国人民解放军军事医学科学院放射医学研究所 Cis-1, the diphenyl ethylene derivatives that 2-replaces are used to prepare the purposes of the medicine of treatment or prevent diabetes
CN101085743B (en) * 2006-06-06 2012-02-15 浙江大德药业集团有限公司 Fluorine-containing alkoxy combretastatin derivative, preparation method and use thereof
SI2219451T1 (en) 2007-11-21 2015-02-27 Oxigene, Inc. Method for treating hematopoietic neoplasms
JP2011016777A (en) * 2009-07-10 2011-01-27 Nipro Corp New cysteine derivative
WO2012025638A1 (en) 2010-08-27 2012-03-01 Universität des Saarlandes Selective 17beta-hydroxysteroid dehydrogenase type 1 inhibitors
US9353150B2 (en) 2012-12-04 2016-05-31 Massachusetts Institute Of Technology Substituted pyrazino[1′,2′:1 ,5]pyrrolo[2,3-b]-indole-1,4-diones for cancer treatment
AU2014228822A1 (en) 2013-03-15 2015-10-01 Memorial Sloan-Kettering Cancer Center HSP90-targeted cardiac imaging and therapy
US11419934B2 (en) 2015-08-18 2022-08-23 Oncotelic Therapeutics, Inc. Use of VDAS to enhance immunomodulating therapies against tumors
WO2017197045A1 (en) 2016-05-11 2017-11-16 Movassaghi Mohammad Convergent and enantioselective total synthesis of communesin analogs
US11932650B2 (en) 2017-05-11 2024-03-19 Massachusetts Institute Of Technology Potent agelastatin derivatives as modulators for cancer invasion and metastasis
US10640508B2 (en) 2017-10-13 2020-05-05 Massachusetts Institute Of Technology Diazene directed modular synthesis of compounds with quaternary carbon centers
CN113227398A (en) 2018-10-29 2021-08-06 塞弗德公司 Exponential-base-3 nucleic acid amplification with nested overlapping primers at reduced amplification time
US11535634B2 (en) 2019-06-05 2022-12-27 Massachusetts Institute Of Technology Compounds, conjugates, and compositions of epipolythiodiketopiperazines and polythiodiketopiperazines and uses thereof

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9106177D0 (en) * 1991-03-22 1991-05-08 Aston Molecules Ltd Substituted diphenylethylenes and analogues or derivatives thereof
TW325458B (en) * 1993-09-08 1998-01-21 Ajinomoto Kk Stilbene derivatives and pharmaceutical compositions comprising the same for anti-cancer
US5561122A (en) * 1994-12-22 1996-10-01 Arizona Board Of Regents Acting On Behalf Of Arizona State University Combretastatin A-4 prodrug
GB9903403D0 (en) * 1999-02-16 1999-04-07 Angiogene Pharm Ltd Substituted stilbene compounds with vascular damaging activity

Also Published As

Publication number Publication date
WO2001012579A3 (en) 2001-10-11
NZ517069A (en) 2004-04-30
EP1206429A2 (en) 2002-05-22
WO2001012579A2 (en) 2001-02-22
CA2379544A1 (en) 2001-02-22
JP2003507356A (en) 2003-02-25

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Legal Events

Date Code Title Description
AT Applications terminated before publication under section 16(1)