GB988331A - 5,12-dihydro-5,7,12,14-tetraazapentacene sulphonic acids, salts thereof, and processes for the production thereof - Google Patents

5,12-dihydro-5,7,12,14-tetraazapentacene sulphonic acids, salts thereof, and processes for the production thereof

Info

Publication number
GB988331A
GB988331A GB3192262A GB3192262A GB988331A GB 988331 A GB988331 A GB 988331A GB 3192262 A GB3192262 A GB 3192262A GB 3192262 A GB3192262 A GB 3192262A GB 988331 A GB988331 A GB 988331A
Authority
GB
United Kingdom
Prior art keywords
tetraazapentacene
dihydro
salts
sulphonic acids
processes
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB3192262A
Inventor
Chikatoyo Naito
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Zeria Kagaku KK
Original Assignee
Zeria Kagaku KK
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zeria Kagaku KK filed Critical Zeria Kagaku KK
Priority to GB3192262A priority Critical patent/GB988331A/en
Publication of GB988331A publication Critical patent/GB988331A/en
Expired legal-status Critical Current

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

The invention comprises 5,12-dihydro-5,7,12, 14 - tetraazapentacene - 2 - or 9 - sulphonic or 2,9-disulphonic acids, their sodium and potassium salts, the preparation thereof by reacting 5,12 - dihydro - 5,7,12,14 - tetraazapentacene with fuming sulphuric acid or with chlorosulphonic acid in the presence of mercuric oxide or mercuric sulphate as a catalyst and if desired refining and separating a mixture of mono- and di-sulphonic acids by column chromatography, and pharmaceutical compositions containing them. The process involves the formation and subsequent hydrolysis of the sulphonyl chloride when chlorosulphonic acid is used. Pharmaceutical compositions useful in the treatment of cataract are in the form of eye drops or solutions for injection and comprise the compounds of the invention together with a suitable carrier.
GB3192262A 1962-08-20 1962-08-20 5,12-dihydro-5,7,12,14-tetraazapentacene sulphonic acids, salts thereof, and processes for the production thereof Expired GB988331A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
GB3192262A GB988331A (en) 1962-08-20 1962-08-20 5,12-dihydro-5,7,12,14-tetraazapentacene sulphonic acids, salts thereof, and processes for the production thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB3192262A GB988331A (en) 1962-08-20 1962-08-20 5,12-dihydro-5,7,12,14-tetraazapentacene sulphonic acids, salts thereof, and processes for the production thereof

Publications (1)

Publication Number Publication Date
GB988331A true GB988331A (en) 1965-04-07

Family

ID=10330390

Family Applications (1)

Application Number Title Priority Date Filing Date
GB3192262A Expired GB988331A (en) 1962-08-20 1962-08-20 5,12-dihydro-5,7,12,14-tetraazapentacene sulphonic acids, salts thereof, and processes for the production thereof

Country Status (1)

Country Link
GB (1) GB988331A (en)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3522257A (en) * 1967-02-28 1970-07-28 Ciba Ltd Tetrazapentacene dyestuffs
WO2009083532A2 (en) * 2007-12-28 2009-07-09 Universite De La Mediterranee Aix-Marseille Ii Novel method for the preparation of derivatives of dihydrotetraazapentacenes, products such as obtained, and uses thereof
US9120803B2 (en) 2012-06-07 2015-09-01 Signa S.A. De C.V. Processes for the preparation of sodium 5,14-dihydrotetraazapentacene polysulfonate, and intermediates thereof

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3522257A (en) * 1967-02-28 1970-07-28 Ciba Ltd Tetrazapentacene dyestuffs
WO2009083532A2 (en) * 2007-12-28 2009-07-09 Universite De La Mediterranee Aix-Marseille Ii Novel method for the preparation of derivatives of dihydrotetraazapentacenes, products such as obtained, and uses thereof
EP2078720A1 (en) * 2007-12-28 2009-07-15 Université de la Méditerranée - Aix-Marseille II Novel method for the preparation of derivatives of dihydrotetraazapentacenes, products such as obtained and uses thereof
WO2009083532A3 (en) * 2007-12-28 2009-11-12 Universite De La Mediterranee Aix-Marseille Ii Novel method for the preparation of derivatives of dihydrotetraazapentacenes, products such as obtained, and uses thereof
US9120803B2 (en) 2012-06-07 2015-09-01 Signa S.A. De C.V. Processes for the preparation of sodium 5,14-dihydrotetraazapentacene polysulfonate, and intermediates thereof

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