GB983073A - Absorbable hemostat - Google Patents
Absorbable hemostatInfo
- Publication number
- GB983073A GB983073A GB11405/61A GB1140561A GB983073A GB 983073 A GB983073 A GB 983073A GB 11405/61 A GB11405/61 A GB 11405/61A GB 1140561 A GB1140561 A GB 1140561A GB 983073 A GB983073 A GB 983073A
- Authority
- GB
- United Kingdom
- Prior art keywords
- trichlorotrifluoroethane
- remove
- isopropyl alcohol
- regenerated cellulose
- oxidized
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 239000002874 hemostatic agent Substances 0.000 title 1
- KFZMGEQAYNKOFK-UHFFFAOYSA-N Isopropanol Chemical compound CC(C)O KFZMGEQAYNKOFK-UHFFFAOYSA-N 0.000 abstract 12
- WFPZPJSADLPSON-UHFFFAOYSA-N dinitrogen tetraoxide Chemical compound [O-][N+](=O)[N+]([O-])=O WFPZPJSADLPSON-UHFFFAOYSA-N 0.000 abstract 8
- 239000000463 material Substances 0.000 abstract 7
- BOSAWIQFTJIYIS-UHFFFAOYSA-N 1,1,1-trichloro-2,2,2-trifluoroethane Chemical compound FC(F)(F)C(Cl)(Cl)Cl BOSAWIQFTJIYIS-UHFFFAOYSA-N 0.000 abstract 4
- 229920000297 Rayon Polymers 0.000 abstract 4
- 239000004627 regenerated cellulose Substances 0.000 abstract 4
- VZGDMQKNWNREIO-UHFFFAOYSA-N tetrachloromethane Chemical compound ClC(Cl)(Cl)Cl VZGDMQKNWNREIO-UHFFFAOYSA-N 0.000 abstract 4
- WSFSSNUMVMOOMR-UHFFFAOYSA-N Formaldehyde Chemical compound O=C WSFSSNUMVMOOMR-UHFFFAOYSA-N 0.000 abstract 3
- 239000000853 adhesive Substances 0.000 abstract 2
- 230000001070 adhesive effect Effects 0.000 abstract 2
- 125000002791 glucosyl group Chemical group C1([C@H](O)[C@@H](O)[C@H](O)[C@H](O1)CO)* 0.000 abstract 2
- 230000003647 oxidation Effects 0.000 abstract 2
- 238000007254 oxidation reaction Methods 0.000 abstract 2
- 238000006116 polymerization reaction Methods 0.000 abstract 2
- 239000002964 rayon Substances 0.000 abstract 2
- 238000005406 washing Methods 0.000 abstract 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 2
- 229920000742 Cotton Polymers 0.000 abstract 1
- 229940030225 antihemorrhagics Drugs 0.000 abstract 1
- 230000000025 haemostatic effect Effects 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 230000001954 sterilising effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/22—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing macromolecular materials
- A61L15/28—Polysaccharides or their derivatives
-
- A61F13/01034—
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/42—Use of materials characterised by their function or physical properties
- A61L15/64—Use of materials characterised by their function or physical properties specially adapted to be resorbable inside the body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F13/00—Bandages or dressings; Absorbent pads
- A61F2013/00089—Wound bandages
- A61F2013/00238—Wound bandages characterised by way of knitting or weaving
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F13/00—Bandages or dressings; Absorbent pads
- A61F2013/00361—Plasters
- A61F2013/00365—Plasters use
- A61F2013/00463—Plasters use haemostatic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F13/00—Bandages or dressings; Absorbent pads
- A61F2013/00361—Plasters
- A61F2013/00365—Plasters use
- A61F2013/00463—Plasters use haemostatic
- A61F2013/00472—Plasters use haemostatic with chemical means
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2400/00—Materials characterised by their function or physical properties
- A61L2400/04—Materials for stopping bleeding
Abstract
A haemostatic dressing material which is absorbable by the body is made of oxidized regenerated cellulose filaments having a denier of 1 to 9, a degree of polymerization prior to oxidation of not more than about 400 glucose units and containing 12 to 25% COOH radical by weight. Chemically crimped carded viscose rayon fibres, which may be needled or knitted rayon fibres, are wrapped around a perforated core and oxidized in a reactor by a solution of dinitrogen tetroxide in trichlorotrifluoroethane for 15 1/2 hours at 24 DEG C. The oxidized regenerated cellulose is then washed three times in carbon tetrachloride or trichlorotrifluoroethane, to remove the dinitrogen tetroxide, followed by washing in 50% aqueous isopropyl alcohol and in 99% isopropyl alcohol, to remove the water. The material is then p dried at room temperature, packaged and sterilized by heat and formaldehyde vapour or other sterilizing process. The material may be used alone in thin layers or with a gauze pad or adhesive dressing or may be combined with cotton to form such a pad or adhesive dressing. The material may be used internally or externally and is gradually absorbed by the body.ALSO:Fibrous web material is made of oxidized regenerated cellulose filaments having a denier of 1 to 9, a degree of polymerization prior to oxidation of not more than about 400 glucose units and containing 12% to 25% COOH radical by weight. Chemically crimped carded viscose rayon fibres, which may be needled or knitted rayon fibres, are wrapped around a perforated core and oxidized in a reactor by a solution of dinitrogen tetroxide in trichlorotrifluoroethane for 15 1/2 hrs at 24 DEG C. The oxidised regenerated cellulose is then washed three times in carbon tetrachloride or trichlorotrifluoroethane to remove the dinitrogen tetroxide, followed by washing in 50% aqueous isopropyl alcohol and in 99% isopropyl alcohol to remove the water. The material is dried at room temperature. The material may be used in thin layers.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US1784060A | 1960-03-28 | 1960-03-28 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB983073A true GB983073A (en) | 1965-02-10 |
Family
ID=21784826
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB11405/61A Expired GB983073A (en) | 1960-03-28 | 1961-03-28 | Absorbable hemostat |
Country Status (7)
| Country | Link |
|---|---|
| BR (1) | BR6127940D0 (en) |
| CH (1) | CH430049A (en) |
| FI (1) | FI41060B (en) |
| FR (1) | FR1071M (en) |
| GB (1) | GB983073A (en) |
| NL (1) | NL262878A (en) |
| SE (1) | SE301213B (en) |
Cited By (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0468114A2 (en) * | 1990-07-24 | 1992-01-29 | CHINA NATIONAL CHEMICALS IMPORT & EXPORT CORPORATION | Soluble haemostatic fabric |
| EP1156765A1 (en) * | 1998-11-12 | 2001-11-28 | Polymer Biosciences, Inc. | Hemostatic polymer useful for rapid blood coagulation and hemostasis |
| EP1378255A2 (en) * | 2002-06-28 | 2004-01-07 | Ethicon, Inc. | Hemostatic wound dressing and method of making same |
| EP1462122A1 (en) * | 2003-03-25 | 2004-09-29 | Ethicon, Inc. | Hemostatic wound dressings and methods of making same |
| US7019191B2 (en) | 2003-03-25 | 2006-03-28 | Ethicon, Inc. | Hemostatic wound dressings and methods of making same |
| WO2007095005A1 (en) * | 2006-02-10 | 2007-08-23 | Z-Medica Corporation | Agents and devices for providing blood clotting functions to wounds |
| WO2007117237A1 (en) * | 2006-04-10 | 2007-10-18 | Ethicon, Inc. | A reinforced absorbable multilayered hemostatic wound dressing and method of making |
| WO2007117238A1 (en) * | 2006-04-10 | 2007-10-18 | Ethicon, Inc. | A reinforced absorbable multilayered fabric for use in medical devices and method of manufacture |
| WO2007143024A2 (en) * | 2006-06-01 | 2007-12-13 | Z-Medica Corporation | Hemostatic device with oxidized cellulose pad |
| WO2008010947A2 (en) * | 2006-07-18 | 2008-01-24 | Z-Medica Corporation | Device for treating wound gaps |
| US7666803B2 (en) | 2004-10-20 | 2010-02-23 | Ethicon, Inc. | Reinforced absorbable multilayered fabric for use in medical devices |
| US8017074B2 (en) | 2004-01-07 | 2011-09-13 | Noxilizer, Inc. | Sterilization system and device |
| US8425837B2 (en) | 2009-02-23 | 2013-04-23 | Noxilizer, Inc. | Device and method for gas sterilization |
| US8703066B2 (en) | 2004-01-07 | 2014-04-22 | Noxilizer, Inc. | Sterilization system and method |
| US8709463B2 (en) | 2003-06-25 | 2014-04-29 | Ethicon, Inc. | Hemostatic devices and methods of making same |
| EP2170412B1 (en) | 2007-07-26 | 2015-03-25 | Symatese | Method for preparing an oxidised cellulose compress |
| US9439997B2 (en) | 2004-10-20 | 2016-09-13 | Ethicon, Inc. | Reinforced absorbable multilayered hemostatis wound dressing |
| EP3148597A4 (en) * | 2014-05-28 | 2018-01-10 | Highland Industries, Inc. | Hemostatic textile |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114010834A (en) * | 2021-10-29 | 2022-02-08 | 上海纳米技术及应用国家工程研究中心有限公司 | Acetyl-containing oxidized regenerated cellulose hemostatic dressing |
-
0
- NL NL262878D patent/NL262878A/xx unknown
-
1961
- 1961-03-27 FR FR856961A patent/FR1071M/en active Active
- 1961-03-27 FI FI0572/61A patent/FI41060B/fi active
- 1961-03-27 BR BR127940/61A patent/BR6127940D0/en unknown
- 1961-03-28 SE SE3306/61A patent/SE301213B/xx unknown
- 1961-03-28 GB GB11405/61A patent/GB983073A/en not_active Expired
- 1961-03-28 CH CH373661A patent/CH430049A/en unknown
Cited By (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0468114A3 (en) * | 1990-07-24 | 1992-03-18 | China National Chemicals Import & Export Corporation | Soluble haemostatic fabric |
| EP0468114A2 (en) * | 1990-07-24 | 1992-01-29 | CHINA NATIONAL CHEMICALS IMPORT & EXPORT CORPORATION | Soluble haemostatic fabric |
| EP1156765A1 (en) * | 1998-11-12 | 2001-11-28 | Polymer Biosciences, Inc. | Hemostatic polymer useful for rapid blood coagulation and hemostasis |
| EP1156765A4 (en) * | 1998-11-12 | 2002-08-07 | Polymer Biosciences Inc | Hemostatic polymer useful for rapid blood coagulation and hemostasis |
| US7279177B2 (en) | 2002-06-28 | 2007-10-09 | Ethicon, Inc. | Hemostatic wound dressings and methods of making same |
| EP1378255A2 (en) * | 2002-06-28 | 2004-01-07 | Ethicon, Inc. | Hemostatic wound dressing and method of making same |
| EP1378255A3 (en) * | 2002-06-28 | 2004-01-28 | Ethicon, Inc. | Hemostatic wound dressing and method of making same |
| CN100548249C (en) * | 2002-06-28 | 2009-10-14 | 伊西康公司 | Hemostatic wound dressing and preparation method thereof |
| US7252837B2 (en) | 2002-06-28 | 2007-08-07 | Ethicon, Inc. | Hemostatic wound dressing and method of making same |
| EP1462122A1 (en) * | 2003-03-25 | 2004-09-29 | Ethicon, Inc. | Hemostatic wound dressings and methods of making same |
| US7019191B2 (en) | 2003-03-25 | 2006-03-28 | Ethicon, Inc. | Hemostatic wound dressings and methods of making same |
| AU2003204989B2 (en) * | 2003-03-25 | 2008-12-11 | Ethicon, Inc. | Hemostatic wound dressings and methods of making same |
| US8709463B2 (en) | 2003-06-25 | 2014-04-29 | Ethicon, Inc. | Hemostatic devices and methods of making same |
| US8017074B2 (en) | 2004-01-07 | 2011-09-13 | Noxilizer, Inc. | Sterilization system and device |
| US8703066B2 (en) | 2004-01-07 | 2014-04-22 | Noxilizer, Inc. | Sterilization system and method |
| US9180217B2 (en) | 2004-01-07 | 2015-11-10 | Noxilizer, Inc. | Sterilization system and device |
| US8808622B2 (en) | 2004-01-07 | 2014-08-19 | Noxilizer, Inc. | Sterilization system and device |
| US9439997B2 (en) | 2004-10-20 | 2016-09-13 | Ethicon, Inc. | Reinforced absorbable multilayered hemostatis wound dressing |
| US7666803B2 (en) | 2004-10-20 | 2010-02-23 | Ethicon, Inc. | Reinforced absorbable multilayered fabric for use in medical devices |
| US7749204B2 (en) | 2004-10-20 | 2010-07-06 | Ethicon, Inc. | Reinforced absorbable multilayered fabric for use in tissue repair and regeneration |
| WO2007095005A1 (en) * | 2006-02-10 | 2007-08-23 | Z-Medica Corporation | Agents and devices for providing blood clotting functions to wounds |
| WO2007117238A1 (en) * | 2006-04-10 | 2007-10-18 | Ethicon, Inc. | A reinforced absorbable multilayered fabric for use in medical devices and method of manufacture |
| WO2007117237A1 (en) * | 2006-04-10 | 2007-10-18 | Ethicon, Inc. | A reinforced absorbable multilayered hemostatic wound dressing and method of making |
| WO2007143024A2 (en) * | 2006-06-01 | 2007-12-13 | Z-Medica Corporation | Hemostatic device with oxidized cellulose pad |
| WO2007143024A3 (en) * | 2006-06-01 | 2008-03-20 | Raymond J Huey | Hemostatic device with oxidized cellulose pad |
| WO2008010947A2 (en) * | 2006-07-18 | 2008-01-24 | Z-Medica Corporation | Device for treating wound gaps |
| WO2008010947A3 (en) * | 2006-07-18 | 2008-07-10 | Z Medica Corp | Device for treating wound gaps |
| EP2170412B1 (en) | 2007-07-26 | 2015-03-25 | Symatese | Method for preparing an oxidised cellulose compress |
| US8425837B2 (en) | 2009-02-23 | 2013-04-23 | Noxilizer, Inc. | Device and method for gas sterilization |
| US8721984B2 (en) | 2009-02-23 | 2014-05-13 | Noxilizer, Inc. | Device and method for gas sterilization |
| EP3148597A4 (en) * | 2014-05-28 | 2018-01-10 | Highland Industries, Inc. | Hemostatic textile |
Also Published As
| Publication number | Publication date |
|---|---|
| NL262878A (en) | |
| BR6127940D0 (en) | 1973-05-31 |
| CH430049A (en) | 1967-02-15 |
| FR1071M (en) | 1962-01-22 |
| SE301213B (en) | 1968-05-27 |
| FI41060B (en) | 1969-04-30 |
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