GB9825946D0 - Pharmaceutical compounds for the inhibition of hepatitis C virus NS3 protease - Google Patents

Pharmaceutical compounds for the inhibition of hepatitis C virus NS3 protease

Info

Publication number
GB9825946D0
GB9825946D0 GBGB9825946.8A GB9825946A GB9825946D0 GB 9825946 D0 GB9825946 D0 GB 9825946D0 GB 9825946 A GB9825946 A GB 9825946A GB 9825946 D0 GB9825946 D0 GB 9825946D0
Authority
GB
United Kingdom
Prior art keywords
hepatitis
protease
virus
inhibition
pharmaceutical compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
GBGB9825946.8A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Istituto di Ricerche di Biologia Molecolare P Angeletti SpA
Original Assignee
Istituto di Ricerche di Biologia Molecolare P Angeletti SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Istituto di Ricerche di Biologia Molecolare P Angeletti SpA filed Critical Istituto di Ricerche di Biologia Molecolare P Angeletti SpA
Priority to GBGB9825946.8A priority Critical patent/GB9825946D0/en
Publication of GB9825946D0 publication Critical patent/GB9825946D0/en
Priority to PCT/EP1999/009207 priority patent/WO2000031129A1/en
Priority to EP99972641A priority patent/EP1144446A1/en
Priority to CA002352493A priority patent/CA2352493A1/en
Priority to AU13871/00A priority patent/AU764589B2/en
Priority to JP2000583956A priority patent/JP2002530430A/en
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/24011—Flaviviridae
    • C12N2770/24211—Hepacivirus, e.g. hepatitis C virus, hepatitis G virus
    • C12N2770/24222—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
GBGB9825946.8A 1998-11-26 1998-11-26 Pharmaceutical compounds for the inhibition of hepatitis C virus NS3 protease Ceased GB9825946D0 (en)

Priority Applications (6)

Application Number Priority Date Filing Date Title
GBGB9825946.8A GB9825946D0 (en) 1998-11-26 1998-11-26 Pharmaceutical compounds for the inhibition of hepatitis C virus NS3 protease
PCT/EP1999/009207 WO2000031129A1 (en) 1998-11-26 1999-11-24 Pharmaceutical compounds for the inhibition of hepatitis c virus ns3 protease
EP99972641A EP1144446A1 (en) 1998-11-26 1999-11-24 Pharmaceutical compounds for the inhibition of hepatitis c virus ns3 protease
CA002352493A CA2352493A1 (en) 1998-11-26 1999-11-24 Pharmaceutical compounds for the inhibition of hepatitis c virus ns3 protease
AU13871/00A AU764589B2 (en) 1998-11-26 1999-11-24 Pharmaceutical compounds for the inhibition of hepatitis C virus NS3 protease
JP2000583956A JP2002530430A (en) 1998-11-26 1999-11-24 Pharmaceutical composition for inhibiting hepatitis C virus NS3 protease

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB9825946.8A GB9825946D0 (en) 1998-11-26 1998-11-26 Pharmaceutical compounds for the inhibition of hepatitis C virus NS3 protease

Publications (1)

Publication Number Publication Date
GB9825946D0 true GB9825946D0 (en) 1999-01-20

Family

ID=10843111

Family Applications (1)

Application Number Title Priority Date Filing Date
GBGB9825946.8A Ceased GB9825946D0 (en) 1998-11-26 1998-11-26 Pharmaceutical compounds for the inhibition of hepatitis C virus NS3 protease

Country Status (6)

Country Link
EP (1) EP1144446A1 (en)
JP (1) JP2002530430A (en)
AU (1) AU764589B2 (en)
CA (1) CA2352493A1 (en)
GB (1) GB9825946D0 (en)
WO (1) WO2000031129A1 (en)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7119072B2 (en) 2002-01-30 2006-10-10 Boehringer Ingelheim (Canada) Ltd. Macrocyclic peptides active against the hepatitis C virus
US7091184B2 (en) 2002-02-01 2006-08-15 Boehringer Ingelheim International Gmbh Hepatitis C inhibitor tri-peptides
US6642204B2 (en) 2002-02-01 2003-11-04 Boehringer Ingelheim International Gmbh Hepatitis C inhibitor tri-peptides
NZ561851A (en) 2002-04-11 2009-05-31 Vertex Pharma Inhibitors of serine proteases, particularly hepatitis C virus NS3 - NS4 protease
US20050075279A1 (en) 2002-10-25 2005-04-07 Boehringer Ingelheim International Gmbh Macrocyclic peptides active against the hepatitis C virus
PT1654261E (en) 2003-05-21 2008-01-18 Boehringer Ingelheim Int Hepatitis c inhibitor compounds
TW201127828A (en) 2003-09-05 2011-08-16 Vertex Pharma Inhibitors of serine proteases, particularly HCV NS3-NS4A protease
DE602004031645D1 (en) 2003-09-22 2011-04-14 Boehringer Ingelheim Pharma MACROCYCLIC PEPTIDES WITH EFFECT AGAINST HEPATITIS C VIRUS
CA2541634A1 (en) 2003-10-10 2005-04-28 Vertex Pharmaceuticals Incorporated Inhibitors of serine proteases, particularly hcv ns3-ns4a protease
EP1944042A1 (en) 2003-10-27 2008-07-16 Vertex Pharmceuticals Incorporated Combinations for HCV treatment
US8187874B2 (en) 2003-10-27 2012-05-29 Vertex Pharmaceuticals Incorporated Drug discovery method
CA2549851C (en) 2004-01-21 2012-09-11 Boehringer Ingelheim International Gmbh Macrocyclic peptides active against the hepatitis c virus
AU2005212257A1 (en) 2004-02-04 2005-08-25 Vertex Pharmaceuticals Incorporated Inhibitors of serine proteases, particularly HCV NS3-NS4A protease
US20070049593A1 (en) 2004-02-24 2007-03-01 Japan Tobacco Inc. Tetracyclic fused heterocyclic compound and use thereof as HCV polymerase inhibitor
PT1719773E (en) 2004-02-24 2009-06-03 Japan Tobacco Inc Fused heterotetracyclic compounds and use tehreof as hcv polymerase inhibitor
EP1771454B1 (en) 2004-07-20 2011-06-15 Boehringer Ingelheim International GmbH Hepatitis c inhibitor peptide analogs
UY29016A1 (en) 2004-07-20 2006-02-24 Boehringer Ingelheim Int ANALOGS OF INHIBITING DIPEPTIDES OF HEPATITIS C
US7659263B2 (en) 2004-11-12 2010-02-09 Japan Tobacco Inc. Thienopyrrole compound and use thereof as HCV polymerase inhibitor
AU2006275413B2 (en) 2005-08-02 2012-07-19 Vertex Pharmaceuticals Incorporated Inhibitors of serine proteases
EP2357170A1 (en) 2005-08-19 2011-08-17 Vertex Pharmaceuticals Incorporated Processes and intermediates
US8399615B2 (en) 2005-08-19 2013-03-19 Vertex Pharmaceuticals Incorporated Processes and intermediates
AR055395A1 (en) 2005-08-26 2007-08-22 Vertex Pharma INHIBITING COMPOUNDS OF THE ACTIVITY OF SERINA PROTEASA NS3-NS4A OF HEPATITIS C VIRUS
US7655394B2 (en) * 2005-10-28 2010-02-02 Boehringer Ingelheim International Gmbh Hepatitis C virus NS2/3 activity assay
US7705138B2 (en) 2005-11-11 2010-04-27 Vertex Pharmaceuticals Incorporated Hepatitis C virus variants
EP1951748B1 (en) 2005-11-11 2013-07-24 Vertex Pharmaceuticals, Inc. Hepatitis c virus variants
US8017612B2 (en) 2006-04-18 2011-09-13 Japan Tobacco Inc. Piperazine compound and use thereof as a HCV polymerase inhibitor
EP1886685A1 (en) 2006-08-11 2008-02-13 INSERM (Institut National de la Santé et de la Recherche Médicale) Methods, uses and compositions for modulating replication of hcv through the farnesoid x receptor (fxr) activation or inhibition
CN102872461A (en) 2007-05-04 2013-01-16 弗特克斯药品有限公司 Combination therapy for the treatment of hcv infection
WO2012107589A1 (en) 2011-02-11 2012-08-16 INSERM (Institut National de la Santé et de la Recherche Médicale) Methods and pharmaceutical compositions for the treatment and prevention of hcv infections

Also Published As

Publication number Publication date
WO2000031129A1 (en) 2000-06-02
CA2352493A1 (en) 2000-06-02
AU764589B2 (en) 2003-08-21
AU1387100A (en) 2000-06-13
EP1144446A1 (en) 2001-10-17
JP2002530430A (en) 2002-09-17

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Legal Events

Date Code Title Description
AT Applications terminated before publication under section 16(1)