GB979073A - Process for preparing 5-inosinic acid - Google Patents
Process for preparing 5-inosinic acidInfo
- Publication number
- GB979073A GB979073A GB2884961A GB2884961A GB979073A GB 979073 A GB979073 A GB 979073A GB 2884961 A GB2884961 A GB 2884961A GB 2884961 A GB2884961 A GB 2884961A GB 979073 A GB979073 A GB 979073A
- Authority
- GB
- United Kingdom
- Prior art keywords
- inosinic acid
- salt
- staphylococcus
- aqueous solution
- nitrophenyl phosphate
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/26—Preparation of nitrogen-containing carbohydrates
- C12P19/28—N-glycosides
- C12P19/30—Nucleotides
- C12P19/32—Nucleotides having a condensed ring system containing a six-membered ring having two N-atoms in the same ring, e.g. purine nucleotides, nicotineamide-adenine dinucleotide
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Microbiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Abstract
A process for producing 51-inosinic acid comprises preparing an aqueous solution containing inosine and p-nitrophenyl phosphate or a salt thereof, adding to the solution an enzyme source contained in or derived from microorganisms of the genus Flavobacterium, Serratia or Staphylococcus, culturing the resulting medium at a pH of from 3.0 to 5.5 at a temperature of from 30 to 45 DEG C., and thereafter recovering the accumulated 51-inosinic acid. A copper salt and/or sodium fluoride may be added to the medium. The aqueous solution may be prepared by mixing the p-nitrophenyl phosphate or salt thereof with a cultured broth containing inosine produced by fermentation. The enzyme source may be in the form of a cell suspension, dry cells, acetone powder, crude extractor or partially purified enzyme. Some 31- and 21-inosinic acid may be formed when a Staphylococcus is used. The product may be isolated as the sodium salt.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP3410160 | 1960-08-09 | ||
| JP1911461 | 1961-06-02 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB979073A true GB979073A (en) | 1965-01-01 |
Family
ID=26355931
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB2884961A Expired GB979073A (en) | 1960-08-09 | 1961-08-09 | Process for preparing 5-inosinic acid |
Country Status (2)
| Country | Link |
|---|---|
| CH (1) | CH409976A (en) |
| GB (1) | GB979073A (en) |
-
1961
- 1961-08-03 CH CH911761A patent/CH409976A/en unknown
- 1961-08-09 GB GB2884961A patent/GB979073A/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| CH409976A (en) | 1966-03-31 |
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