GB969851A - Acid-addition salts of dialkylaminoalkylguanidines - Google Patents
Acid-addition salts of dialkylaminoalkylguanidinesInfo
- Publication number
- GB969851A GB969851A GB39691/60A GB3969160A GB969851A GB 969851 A GB969851 A GB 969851A GB 39691/60 A GB39691/60 A GB 39691/60A GB 3969160 A GB3969160 A GB 3969160A GB 969851 A GB969851 A GB 969851A
- Authority
- GB
- United Kingdom
- Prior art keywords
- acid addition
- compound
- addition salt
- formula
- emulsions
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C277/00—Preparation of guanidine or its derivatives, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
- C07C277/08—Preparation of guanidine or its derivatives, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups of substituted guanidines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
- C07C279/04—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
- C07C279/04—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton
- C07C279/14—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton being further substituted by carboxyl groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C281/00—Derivatives of carbonic acid containing functional groups covered by groups C07C269/00 - C07C279/00 in which at least one nitrogen atom of these functional groups is further bound to another nitrogen atom not being part of a nitro or nitroso group
- C07C281/16—Compounds containing any of the groups, e.g. aminoguanidine
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
The invention comprises non-toxic, pharmaceutically-acceptable acid addition salts of compounds of the general formula <FORM:0969851/C1/1> (wherein R1 and R2, which may be the same or different, represent alkyl radicals of not more than four carbon atoms and n is 2 or 3), pharmaceutical preparations containing them, and their preparation by heating a compound of the formula <FORM:0969851/C1/2> or an acid addition salt thereof, with a compound of the formula: <FORM:0969851/C1/3> (wherein Alk represents an alkyl radical of not more than six carbon atoms), or an acid addition salt thereof and, if necessary, converting the compound so obtained into a non-toxic, pharmaceutically-acceptabl acid addition salt. The compounds of the invention possess hypotensive properties and may be administered orally or parenterally in the form of pharmaceutical preparations (e.g. tablets, capsules, pills, dispersible powders, granules, emulsions, suspensions, syrups, elixirs and sterile aqueous or non-aqueous solutions, suspensions and emulsions) containing them in admixture with an inert diluent or carrier. According to the Provisional Specification, n may represent 2 to 5.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB39691/60A GB969851A (en) | 1960-11-18 | 1960-11-18 | Acid-addition salts of dialkylaminoalkylguanidines |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB39691/60A GB969851A (en) | 1960-11-18 | 1960-11-18 | Acid-addition salts of dialkylaminoalkylguanidines |
Publications (1)
Publication Number | Publication Date |
---|---|
GB969851A true GB969851A (en) | 1964-09-16 |
Family
ID=10410943
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB39691/60A Expired GB969851A (en) | 1960-11-18 | 1960-11-18 | Acid-addition salts of dialkylaminoalkylguanidines |
Country Status (1)
Country | Link |
---|---|
GB (1) | GB969851A (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2418789A1 (en) * | 1978-03-02 | 1979-09-28 | Goldschmidt Ag Th | NEW GUANIDINE SALTS, PROCESS ALLOWING THEIR PRODUCTION AND MICROBICIDE PREPARATIONS CONTAINING THEM |
-
1960
- 1960-11-18 GB GB39691/60A patent/GB969851A/en not_active Expired
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2418789A1 (en) * | 1978-03-02 | 1979-09-28 | Goldschmidt Ag Th | NEW GUANIDINE SALTS, PROCESS ALLOWING THEIR PRODUCTION AND MICROBICIDE PREPARATIONS CONTAINING THEM |
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