GB9623833D0 - Chemical compound - Google Patents
Chemical compoundInfo
- Publication number
- GB9623833D0 GB9623833D0 GBGB9623833.2A GB9623833A GB9623833D0 GB 9623833 D0 GB9623833 D0 GB 9623833D0 GB 9623833 A GB9623833 A GB 9623833A GB 9623833 D0 GB9623833 D0 GB 9623833D0
- Authority
- GB
- United Kingdom
- Prior art keywords
- chemical compound
- chemical
- compound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
- A61K31/222—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin with compounds having aromatic groups, e.g. dipivefrine, ibopamine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
- A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/235—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
- C07C235/42—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton
- C07C235/44—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton with carbon atoms of carboxamide groups and singly-bound oxygen atoms bound to carbon atoms of the same non-condensed six-membered aromatic ring
- C07C235/56—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton with carbon atoms of carboxamide groups and singly-bound oxygen atoms bound to carbon atoms of the same non-condensed six-membered aromatic ring having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a six-membered aromatic ring
Priority Applications (8)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9623833.2A GB9623833D0 (en) | 1996-11-16 | 1996-11-16 | Chemical compound |
| EP97912325A EP0941084A1 (en) | 1996-11-16 | 1997-11-12 | Raf kinase inhibitors |
| PCT/GB1997/003102 WO1998022103A1 (en) | 1996-11-16 | 1997-11-12 | Raf kinase inhibitors |
| AU49562/97A AU4956297A (en) | 1996-11-16 | 1997-11-12 | Raf kinase inhibitors |
| CA002267782A CA2267782A1 (en) | 1996-11-16 | 1997-11-12 | Raf kinase inhibitors |
| JP52331698A JP2001504478A (en) | 1996-11-16 | 1997-11-12 | RAF kinase inhibitor |
| ZA9710314A ZA9710314B (en) | 1996-11-16 | 1997-11-14 | Chemical compounds. |
| NO992336A NO992336L (en) | 1996-11-16 | 1999-05-14 | Raf kinase inhibitors |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9623833.2A GB9623833D0 (en) | 1996-11-16 | 1996-11-16 | Chemical compound |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB9623833D0 true GB9623833D0 (en) | 1997-01-08 |
Family
ID=10803023
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GBGB9623833.2A Pending GB9623833D0 (en) | 1996-11-16 | 1996-11-16 | Chemical compound |
Country Status (8)
| Country | Link |
|---|---|
| EP (1) | EP0941084A1 (en) |
| JP (1) | JP2001504478A (en) |
| AU (1) | AU4956297A (en) |
| CA (1) | CA2267782A1 (en) |
| GB (1) | GB9623833D0 (en) |
| NO (1) | NO992336L (en) |
| WO (1) | WO1998022103A1 (en) |
| ZA (1) | ZA9710314B (en) |
Families Citing this family (56)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7772432B2 (en) | 1991-09-19 | 2010-08-10 | Astrazeneca Ab | Amidobenzamide derivatives which are useful as cytokine inhibitors |
| GB9816837D0 (en) | 1998-08-04 | 1998-09-30 | Zeneca Ltd | Amide derivatives |
| DK1017378T3 (en) | 1997-09-23 | 2003-03-17 | Astrazeneca Ab | Amide derivatives to treat diseases mediated by cytokines |
| DE69834842T2 (en) * | 1997-12-22 | 2007-05-10 | Bayer Pharmaceuticals Corp., West Haven | INHIBITION OF RAF-KINASE USING ARYL AND HETEROARYL SUBSTITUTED HETEROCYCLIC UREA |
| NZ505844A (en) * | 1997-12-22 | 2003-10-31 | Bayer Ag | Inhibition of raf kinase using substituted heterocyclic ureas |
| PT1077930E (en) * | 1998-05-15 | 2005-03-31 | Astrazeneca Ab | BENZAMIDE DERIVATIVES FOR THE TREATMENT OF DISEASES MEDIATED BY CYTOKINES |
| AU749293B2 (en) | 1998-05-15 | 2002-06-20 | Astrazeneca Ab | Benzamide derivatives for the treatment of diseases mediated by cytokines |
| WO2000007991A1 (en) | 1998-08-04 | 2000-02-17 | Astrazeneca Ab | Amide derivatives useful as inhibitors of the production of cytokines |
| DE69912823T2 (en) | 1998-09-25 | 2004-09-23 | Astrazeneca Ab | BENZAMIDE DERIVATIVES AND THEIR USE AS CYTOKINE INHIBITORS |
| IL142257A0 (en) | 1998-10-01 | 2002-03-10 | Astrazeneca Ab | Amide derivatives, process for their preparation, compositions containing them and use thereof in the manufacture of a medicament for the treatment of cytokine-mediated diseases |
| AU6513199A (en) | 1998-10-09 | 2000-05-01 | Anadys Pharmaceuticals, Inc. | Aryldiamine derivatives useful as antibacterial agents |
| US8124630B2 (en) | 1999-01-13 | 2012-02-28 | Bayer Healthcare Llc | ω-carboxyaryl substituted diphenyl ureas as raf kinase inhibitors |
| EP2298311B1 (en) | 1999-01-13 | 2012-05-09 | Bayer HealthCare LLC | w-Carboxy aryl substituted diphenyl ureas as p38 kinase inhibitors |
| WO2000055120A1 (en) | 1999-03-17 | 2000-09-21 | Astrazeneca Ab | Amide derivatives |
| EP1163237B1 (en) | 1999-03-17 | 2004-05-06 | AstraZeneca AB | Amide derivatives |
| GB9906566D0 (en) | 1999-03-23 | 1999-05-19 | Zeneca Ltd | Chemical compounds |
| GB9924092D0 (en) | 1999-10-13 | 1999-12-15 | Zeneca Ltd | Pyrimidine derivatives |
| WO2003056036A2 (en) * | 2001-12-21 | 2003-07-10 | The Wellcome Trust | Genes |
| MXPA04007832A (en) | 2002-02-11 | 2005-09-08 | Bayer Pharmaceuticals Corp | Aryl ureas with angiogenesis inhibiting activity. |
| WO2003068746A1 (en) | 2002-02-11 | 2003-08-21 | Bayer Pharmaceuticals Corporation | Aryl ureas as kinase inhibitors |
| US7202257B2 (en) | 2003-12-24 | 2007-04-10 | Deciphera Pharmaceuticals, Llc | Anti-inflammatory medicaments |
| US7279576B2 (en) | 2002-12-31 | 2007-10-09 | Deciphera Pharmaceuticals, Llc | Anti-cancer medicaments |
| US7144911B2 (en) | 2002-12-31 | 2006-12-05 | Deciphera Pharmaceuticals Llc | Anti-inflammatory medicaments |
| WO2004064733A2 (en) * | 2003-01-15 | 2004-08-05 | Board Of Regents, University Of Texas System | The use of c-raf inhibitors for the treatment of neurodegenerative diseases |
| CA2526617C (en) | 2003-05-20 | 2015-04-28 | Bayer Pharmaceuticals Corporation | Diaryl ureas with kinase inhibiting activity |
| EP1643991B1 (en) * | 2003-07-11 | 2014-03-12 | Merck Patent GmbH | Benzimidazole carboxamides as raf kinase inhibitors |
| UA84156C2 (en) | 2003-07-23 | 2008-09-25 | Байер Фармасьютикалс Корпорейшн | Fluoro substituted omega-carboxyaryl diphenyl urea for the treatment and prevention of diseases and conditions |
| GB0324790D0 (en) | 2003-10-24 | 2003-11-26 | Astrazeneca Ab | Amide derivatives |
| US20060025485A1 (en) * | 2004-07-01 | 2006-02-02 | Kyle Holen | Hydroxybenazamide compounds for treatment of cancer |
| BRPI0514679A (en) * | 2004-09-01 | 2008-06-17 | Astrazeneca Ab | compound, process for preparing same, pharmaceutical composition, use of a compound, and methods for producing an inhibitory effect of b-raf and an anticancer effect on a warm-blooded animal, and for treating a disease or condition |
| WO2006067445A2 (en) * | 2004-12-22 | 2006-06-29 | Astrazeneca Ab | Csf-1r kinase inhibitors |
| WO2006076706A1 (en) * | 2005-01-14 | 2006-07-20 | Millennium Pharmaceuticals, Inc. | Cinnamide and hydrocinnamide derivatives with raf-kinase inhibitory activity |
| JP5225857B2 (en) * | 2005-11-14 | 2013-07-03 | ジェネンテック，インコーポレイティド | Bisamide inhibitors of hedgehog signaling |
| EP2146717A4 (en) | 2007-04-20 | 2010-08-11 | Deciphera Pharmaceuticals Llc | Kinase inhibitors useful for the treatment of myleoproliferative diseases and other proliferative diseases |
| JP2013526513A (en) * | 2010-05-11 | 2013-06-24 | クリサニ バイオサイエンシーズ プライベート リミッテッド | 4,6-Dibenzylamine-2-methyl-pyrimidine derivatives and their use for cancer treatment |
| US9198911B2 (en) | 2010-11-02 | 2015-12-01 | The Trustees Of Columbia University In The City Of New York | Methods for treating hair loss disorders |
| US8906258B2 (en) | 2011-08-29 | 2014-12-09 | Ticona Llc | Heat-resistant liquid crystalline polymer composition having a low melting temperature |
| JP2014525500A (en) | 2011-08-29 | 2014-09-29 | ティコナ・エルエルシー | Melt polymerization of low melt viscosity liquid crystal polymers |
| WO2013032975A1 (en) | 2011-08-29 | 2013-03-07 | Ticona Llc | Thermotropic liquid crystalline polymer with improved low shear viscosity |
| WO2013032967A1 (en) | 2011-08-29 | 2013-03-07 | Ticona Llc | Cast molded parts formed form a liquid crystalline polymer |
| JP2014529627A (en) | 2011-08-29 | 2014-11-13 | ティコナ・エルエルシー | Aromatic amide compounds |
| US9051514B2 (en) | 2011-08-29 | 2015-06-09 | Ticona Llc | High flow liquid crystalline polymer composition |
| KR20140059825A (en) | 2011-08-29 | 2014-05-16 | 티코나 엘엘씨 | High flow liquid crystalline polymer composition |
| WO2013032971A1 (en) | 2011-08-29 | 2013-03-07 | Ticona Llc | Melt-extruded substrate for use in thermoformed articles |
| PL2830662T3 (en) | 2012-03-29 | 2019-02-28 | The Trustees Of Columbia University In The City Of New York | Methods for treating hair loss disorders |
| US8461179B1 (en) | 2012-06-07 | 2013-06-11 | Deciphera Pharmaceuticals, Llc | Dihydronaphthyridines and related compounds useful as kinase inhibitors for the treatment of proliferative diseases |
| WO2014130275A2 (en) | 2013-02-22 | 2014-08-28 | Ticona Llc | High performance polymer composition with improved flow properties |
| WO2015041533A1 (en) | 2013-09-20 | 2015-03-26 | Stichting Het Nederlands Kanker Instituut | Rock in combination with mapk-pathway |
| WO2015041534A1 (en) | 2013-09-20 | 2015-03-26 | Stichting Het Nederlands Kanker Instituut | P90rsk in combination with raf/erk/mek |
| WO2015156674A2 (en) | 2014-04-10 | 2015-10-15 | Stichting Het Nederlands Kanker Instituut | Method for treating cancer |
| WO2015178770A1 (en) | 2014-05-19 | 2015-11-26 | Stichting Het Nederlands Kanker Instituut | Compositions for cancer treatment |
| TW202122082A (en) | 2019-08-12 | 2021-06-16 | 美商迪賽孚爾製藥有限公司 | Methods of treating gastrointestinal stromal tumors |
| MX2022001863A (en) | 2019-08-12 | 2022-05-30 | Deciphera Pharmaceuticals Llc | Ripretinib for treating gastrointestinal stromal tumors. |
| LT4084778T (en) | 2019-12-30 | 2024-01-25 | Deciphera Pharmaceuticals, Llc | Amorphous kinase inhibitor formulations and methods of use thereof |
| IL293864A (en) | 2019-12-30 | 2022-08-01 | Deciphera Pharmaceuticals Llc | Compositions of 1-(4-bromo-5-(1-ethyl-7-(methylamino)-2-oxo-1,2-dihydro-1,6-naphthyridin-3-yl)-2-fluorophenyl)-3-phenylurea |
| US11779572B1 (en) | 2022-09-02 | 2023-10-10 | Deciphera Pharmaceuticals, Llc | Methods of treating gastrointestinal stromal tumors |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1993004170A1 (en) * | 1991-08-23 | 1993-03-04 | The United States Of America Represented By The Secretary, Department Of Health And Human Services | Raf protein kinase therapeutics |
-
1996
- 1996-11-16 GB GBGB9623833.2A patent/GB9623833D0/en active Pending
-
1997
- 1997-11-12 JP JP52331698A patent/JP2001504478A/en active Pending
- 1997-11-12 WO PCT/GB1997/003102 patent/WO1998022103A1/en not_active Application Discontinuation
- 1997-11-12 AU AU49562/97A patent/AU4956297A/en not_active Abandoned
- 1997-11-12 CA CA002267782A patent/CA2267782A1/en not_active Abandoned
- 1997-11-12 EP EP97912325A patent/EP0941084A1/en not_active Withdrawn
- 1997-11-14 ZA ZA9710314A patent/ZA9710314B/en unknown
-
1999
- 1999-05-14 NO NO992336A patent/NO992336L/en not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| JP2001504478A (en) | 2001-04-03 |
| EP0941084A1 (en) | 1999-09-15 |
| NO992336D0 (en) | 1999-05-14 |
| AU4956297A (en) | 1998-06-10 |
| ZA9710314B (en) | 1998-05-18 |
| WO1998022103A1 (en) | 1998-05-28 |
| NO992336L (en) | 1999-05-14 |
| CA2267782A1 (en) | 1998-05-28 |
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