GB9404046D0 - Novel compounds - Google Patents
Novel compoundsInfo
- Publication number
- GB9404046D0 GB9404046D0 GB9404046A GB9404046A GB9404046D0 GB 9404046 D0 GB9404046 D0 GB 9404046D0 GB 9404046 A GB9404046 A GB 9404046A GB 9404046 A GB9404046 A GB 9404046A GB 9404046 D0 GB9404046 D0 GB 9404046D0
- Authority
- GB
- United Kingdom
- Prior art keywords
- novel compounds
- novel
- compounds
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/68—Halogen atoms
Priority Applications (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB9404046A GB9404046D0 (en) | 1994-03-03 | 1994-03-03 | Novel compounds |
US08/702,528 US5665753A (en) | 1994-03-03 | 1995-03-03 | Cytokine inhibiting imidazole substituted hydroxamic acid derivatives |
JP7523024A JPH09509940A (en) | 1994-03-03 | 1995-03-03 | Cytokine-inhibiting imidazole-substituted hydroxamic acid derivatives |
PCT/US1995/002606 WO1995023790A1 (en) | 1994-03-03 | 1995-03-03 | Cytokine inhibiting imidazole substituted hydroxamic acid derivatives |
EP95912688A EP0748313A4 (en) | 1994-03-03 | 1995-03-03 | Cytokine inhibiting imidazole substituted hydroxamic acid derivatives |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB9404046A GB9404046D0 (en) | 1994-03-03 | 1994-03-03 | Novel compounds |
Publications (1)
Publication Number | Publication Date |
---|---|
GB9404046D0 true GB9404046D0 (en) | 1994-04-20 |
Family
ID=10751186
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB9404046A Pending GB9404046D0 (en) | 1994-03-03 | 1994-03-03 | Novel compounds |
Country Status (4)
Country | Link |
---|---|
EP (1) | EP0748313A4 (en) |
JP (1) | JPH09509940A (en) |
GB (1) | GB9404046D0 (en) |
WO (1) | WO1995023790A1 (en) |
Families Citing this family (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9601042D0 (en) * | 1996-01-17 | 1996-03-20 | Smithkline Beecham Plc | Medical use |
US5703092A (en) * | 1995-04-18 | 1997-12-30 | The Dupont Merck Pharmaceutical Company | Hydroxamic acid compounds as metalloprotease and TNF inhibitors |
WO1997019075A1 (en) * | 1995-11-22 | 1997-05-29 | Darwin Discovery Limited | Mercaptoalkylpeptidyl compounds having an imidazole substituent and their use as inhibitors of matrix metalloproteinases (mmp) and/or tumour necrosis factor (tnf) |
US6127427A (en) | 1995-11-23 | 2000-10-03 | British Biotech Pharmaceuticals Limited | Metalloproteinase inhibitors |
US6566384B1 (en) | 1996-08-07 | 2003-05-20 | Darwin Discovery Ltd. | Hydroxamic and carboxylic acid derivatives having MMP and TNF inhibitory activity |
DE69729007T2 (en) * | 1996-08-07 | 2005-04-07 | Darwin Discovery Ltd., Slough | HYDROXAMIC ACID AND CARBOXYLIC DERIVATIVES WITH MMP AND TNF HEMMENDER EFFECT |
US6462023B1 (en) | 1996-09-10 | 2002-10-08 | British Biotech Pharmaceuticals, Ltd. | Cytostatic agents |
ATE220660T1 (en) | 1996-09-10 | 2002-08-15 | British Biotech Pharm | CYTOSTATIC HYDROXAMIC ACID DERIVATIVES |
US5952320A (en) * | 1997-01-07 | 1999-09-14 | Abbott Laboratories | Macrocyclic inhibitors of matrix metalloproteinases and TNFα secretion |
US5985911A (en) * | 1997-01-07 | 1999-11-16 | Abbott Laboratories | C-terminal ketone inhibitors of matrix metalloproteinases and TNFα secretion |
US6329418B1 (en) | 1998-04-14 | 2001-12-11 | The Procter & Gamble Company | Substituted pyrrolidine hydroxamate metalloprotease inhibitors |
US6288261B1 (en) | 1998-12-18 | 2001-09-11 | Abbott Laboratories | Inhibitors of matrix metalloproteinases |
EP1339400B1 (en) | 2000-11-23 | 2005-06-29 | Vernalis (Oxford) Ltd | N-formyl hydroxylamine derivatives as inhibitors of bacterial polypeptide deformylase for treating microbial infections |
GB0031321D0 (en) * | 2000-12-21 | 2001-02-07 | Pfizer Ltd | Treatment |
US6716861B2 (en) | 2000-12-21 | 2004-04-06 | Pfizer, Inc. | 3-ox(adi)azolylpropanohydroxamic acids useful as procollagen C-proteinase inhibitors |
US6645993B2 (en) | 2001-03-30 | 2003-11-11 | Warner-Lambert Company | 3-heterocyclylpropanohydroxamic acid PCP inhibitors |
GB0204159D0 (en) * | 2002-02-22 | 2002-04-10 | British Biotech Pharm | Metalloproteinase inhibitors |
WO2004101537A1 (en) * | 2003-05-17 | 2004-11-25 | British Biotech Pharmaceuticals Ltd | Metalloproteinase inhibitors |
CN114957160A (en) * | 2022-03-28 | 2022-08-30 | 北京理工大学 | 2,4, 5-trisubstituted thiazole compound, preparation method and application thereof |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DK77487A (en) * | 1986-03-11 | 1987-09-12 | Hoffmann La Roche | hydroxylamine |
GB8827308D0 (en) * | 1988-11-23 | 1988-12-29 | British Bio Technology | Compounds |
GB8827305D0 (en) * | 1988-11-23 | 1988-12-29 | British Bio Technology | Compounds |
GB9102635D0 (en) * | 1991-02-07 | 1991-03-27 | British Bio Technology | Compounds |
GB9215665D0 (en) * | 1992-07-23 | 1992-09-09 | British Bio Technology | Compounds |
NZ262447A (en) * | 1993-03-16 | 1996-07-26 | British Biotech Pharm | Hydroxamic acid derivatives and their use as pharmaceutical agents |
-
1994
- 1994-03-03 GB GB9404046A patent/GB9404046D0/en active Pending
-
1995
- 1995-03-03 WO PCT/US1995/002606 patent/WO1995023790A1/en not_active Application Discontinuation
- 1995-03-03 JP JP7523024A patent/JPH09509940A/en active Pending
- 1995-03-03 EP EP95912688A patent/EP0748313A4/en not_active Withdrawn
Also Published As
Publication number | Publication date |
---|---|
EP0748313A1 (en) | 1996-12-18 |
WO1995023790A1 (en) | 1995-09-08 |
EP0748313A4 (en) | 1997-06-11 |
JPH09509940A (en) | 1997-10-07 |
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