GB9404046D0 - Novel compounds - Google Patents

Novel compounds

Info

Publication number
GB9404046D0
GB9404046D0 GB9404046A GB9404046A GB9404046D0 GB 9404046 D0 GB9404046 D0 GB 9404046D0 GB 9404046 A GB9404046 A GB 9404046A GB 9404046 A GB9404046 A GB 9404046A GB 9404046 D0 GB9404046 D0 GB 9404046D0
Authority
GB
United Kingdom
Prior art keywords
novel compounds
novel
compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
GB9404046A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SmithKline Beecham Corp
Original Assignee
SmithKline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SmithKline Beecham Corp filed Critical SmithKline Beecham Corp
Priority to GB9404046A priority Critical patent/GB9404046D0/en
Publication of GB9404046D0 publication Critical patent/GB9404046D0/en
Priority to US08/702,528 priority patent/US5665753A/en
Priority to JP7523024A priority patent/JPH09509940A/en
Priority to PCT/US1995/002606 priority patent/WO1995023790A1/en
Priority to EP95912688A priority patent/EP0748313A4/en
Pending legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/64Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/68Halogen atoms
GB9404046A 1994-03-03 1994-03-03 Novel compounds Pending GB9404046D0 (en)

Priority Applications (5)

Application Number Priority Date Filing Date Title
GB9404046A GB9404046D0 (en) 1994-03-03 1994-03-03 Novel compounds
US08/702,528 US5665753A (en) 1994-03-03 1995-03-03 Cytokine inhibiting imidazole substituted hydroxamic acid derivatives
JP7523024A JPH09509940A (en) 1994-03-03 1995-03-03 Cytokine-inhibiting imidazole-substituted hydroxamic acid derivatives
PCT/US1995/002606 WO1995023790A1 (en) 1994-03-03 1995-03-03 Cytokine inhibiting imidazole substituted hydroxamic acid derivatives
EP95912688A EP0748313A4 (en) 1994-03-03 1995-03-03 Cytokine inhibiting imidazole substituted hydroxamic acid derivatives

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB9404046A GB9404046D0 (en) 1994-03-03 1994-03-03 Novel compounds

Publications (1)

Publication Number Publication Date
GB9404046D0 true GB9404046D0 (en) 1994-04-20

Family

ID=10751186

Family Applications (1)

Application Number Title Priority Date Filing Date
GB9404046A Pending GB9404046D0 (en) 1994-03-03 1994-03-03 Novel compounds

Country Status (4)

Country Link
EP (1) EP0748313A4 (en)
JP (1) JPH09509940A (en)
GB (1) GB9404046D0 (en)
WO (1) WO1995023790A1 (en)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9601042D0 (en) * 1996-01-17 1996-03-20 Smithkline Beecham Plc Medical use
US5703092A (en) * 1995-04-18 1997-12-30 The Dupont Merck Pharmaceutical Company Hydroxamic acid compounds as metalloprotease and TNF inhibitors
WO1997019075A1 (en) * 1995-11-22 1997-05-29 Darwin Discovery Limited Mercaptoalkylpeptidyl compounds having an imidazole substituent and their use as inhibitors of matrix metalloproteinases (mmp) and/or tumour necrosis factor (tnf)
US6127427A (en) 1995-11-23 2000-10-03 British Biotech Pharmaceuticals Limited Metalloproteinase inhibitors
US6566384B1 (en) 1996-08-07 2003-05-20 Darwin Discovery Ltd. Hydroxamic and carboxylic acid derivatives having MMP and TNF inhibitory activity
DE69729007T2 (en) * 1996-08-07 2005-04-07 Darwin Discovery Ltd., Slough HYDROXAMIC ACID AND CARBOXYLIC DERIVATIVES WITH MMP AND TNF HEMMENDER EFFECT
US6462023B1 (en) 1996-09-10 2002-10-08 British Biotech Pharmaceuticals, Ltd. Cytostatic agents
ATE220660T1 (en) 1996-09-10 2002-08-15 British Biotech Pharm CYTOSTATIC HYDROXAMIC ACID DERIVATIVES
US5952320A (en) * 1997-01-07 1999-09-14 Abbott Laboratories Macrocyclic inhibitors of matrix metalloproteinases and TNFα secretion
US5985911A (en) * 1997-01-07 1999-11-16 Abbott Laboratories C-terminal ketone inhibitors of matrix metalloproteinases and TNFα secretion
US6329418B1 (en) 1998-04-14 2001-12-11 The Procter & Gamble Company Substituted pyrrolidine hydroxamate metalloprotease inhibitors
US6288261B1 (en) 1998-12-18 2001-09-11 Abbott Laboratories Inhibitors of matrix metalloproteinases
EP1339400B1 (en) 2000-11-23 2005-06-29 Vernalis (Oxford) Ltd N-formyl hydroxylamine derivatives as inhibitors of bacterial polypeptide deformylase for treating microbial infections
GB0031321D0 (en) * 2000-12-21 2001-02-07 Pfizer Ltd Treatment
US6716861B2 (en) 2000-12-21 2004-04-06 Pfizer, Inc. 3-ox(adi)azolylpropanohydroxamic acids useful as procollagen C-proteinase inhibitors
US6645993B2 (en) 2001-03-30 2003-11-11 Warner-Lambert Company 3-heterocyclylpropanohydroxamic acid PCP inhibitors
GB0204159D0 (en) * 2002-02-22 2002-04-10 British Biotech Pharm Metalloproteinase inhibitors
WO2004101537A1 (en) * 2003-05-17 2004-11-25 British Biotech Pharmaceuticals Ltd Metalloproteinase inhibitors
CN114957160A (en) * 2022-03-28 2022-08-30 北京理工大学 2,4, 5-trisubstituted thiazole compound, preparation method and application thereof

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK77487A (en) * 1986-03-11 1987-09-12 Hoffmann La Roche hydroxylamine
GB8827308D0 (en) * 1988-11-23 1988-12-29 British Bio Technology Compounds
GB8827305D0 (en) * 1988-11-23 1988-12-29 British Bio Technology Compounds
GB9102635D0 (en) * 1991-02-07 1991-03-27 British Bio Technology Compounds
GB9215665D0 (en) * 1992-07-23 1992-09-09 British Bio Technology Compounds
NZ262447A (en) * 1993-03-16 1996-07-26 British Biotech Pharm Hydroxamic acid derivatives and their use as pharmaceutical agents

Also Published As

Publication number Publication date
EP0748313A1 (en) 1996-12-18
WO1995023790A1 (en) 1995-09-08
EP0748313A4 (en) 1997-06-11
JPH09509940A (en) 1997-10-07

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