GB925567A - Improvements in and relating to lysine nicotinate and its therapeutic applications - Google Patents
Improvements in and relating to lysine nicotinate and its therapeutic applicationsInfo
- Publication number
- GB925567A GB925567A GB27214/61A GB2721461A GB925567A GB 925567 A GB925567 A GB 925567A GB 27214/61 A GB27214/61 A GB 27214/61A GB 2721461 A GB2721461 A GB 2721461A GB 925567 A GB925567 A GB 925567A
- Authority
- GB
- United Kingdom
- Prior art keywords
- relating
- therapeutic applications
- nicotinate
- lysine nicotinate
- lysine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- KDXKERNSBIXSRK-UHFFFAOYSA-N Lysine Natural products NCCCCC(N)C(O)=O KDXKERNSBIXSRK-UHFFFAOYSA-N 0.000 title abstract 2
- 239000004472 Lysine Substances 0.000 title abstract 2
- PVNIIMVLHYAWGP-UHFFFAOYSA-N Niacin Chemical compound OC(=O)C1=CC=CN=C1 PVNIIMVLHYAWGP-UHFFFAOYSA-N 0.000 title abstract 2
- 235000001968 nicotinic acid Nutrition 0.000 title abstract 2
- 239000011664 nicotinic acid Substances 0.000 title abstract 2
- 230000001225 therapeutic effect Effects 0.000 title abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
- 206010020961 Hypocholesterolaemia Diseases 0.000 abstract 1
- 230000001939 inductive effect Effects 0.000 abstract 1
- 238000002347 injection Methods 0.000 abstract 1
- 239000007924 injection Substances 0.000 abstract 1
- 239000000829 suppository Substances 0.000 abstract 1
- 230000000304 vasodilatating effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/79—Acids; Esters
- C07D213/80—Acids; Esters in position 3
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/16—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
- Preliminary Treatment Of Fibers (AREA)
Abstract
The invention comprises lysine nicotinate having the formula: <FORM:0925567/IV(a)/1> and a therapeutic composition thereof having hypocholesterolemia inducing properties and vaso-dilating properties. Such compositions are administered orally as tablets, by injection or in the form of suppositories.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR834519A FR84M (en) | 1960-07-29 | 1960-07-29 |
Publications (1)
Publication Number | Publication Date |
---|---|
GB925567A true GB925567A (en) | 1963-05-08 |
Family
ID=8736586
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB27214/61A Expired GB925567A (en) | 1960-07-29 | 1961-07-27 | Improvements in and relating to lysine nicotinate and its therapeutic applications |
Country Status (5)
Country | Link |
---|---|
BE (1) | BE606636A (en) |
CH (1) | CH394199A (en) |
ES (1) | ES269440A1 (en) |
FR (1) | FR84M (en) |
GB (1) | GB925567A (en) |
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3973027A (en) * | 1974-03-07 | 1976-08-03 | Roemmers Sociedad Anonima Industrial, Comercial Y Financiera | Analgesic method containing Lysine 2-(2-methyl-3-chloro-anilino)-3-nicotinate |
US4332792A (en) * | 1980-07-14 | 1982-06-01 | Zoecon Corporation | Insect attractant |
WO1991007188A1 (en) * | 1989-11-22 | 1991-05-30 | Adrian Barbul | Method for reducing blood cholesterol using arginine |
JP2021525279A (en) * | 2018-05-22 | 2021-09-24 | ジャンプスタート ファーティリティ ピーティーワイ リミテッド | Amino acid salt of nicotinic acid riboside as an anti-aging agent |
-
1960
- 1960-07-29 FR FR834519A patent/FR84M/fr active Active
-
1961
- 1961-07-27 CH CH884361A patent/CH394199A/en unknown
- 1961-07-27 BE BE606636A patent/BE606636A/en unknown
- 1961-07-27 GB GB27214/61A patent/GB925567A/en not_active Expired
- 1961-07-28 ES ES0269440A patent/ES269440A1/en not_active Expired
Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3973027A (en) * | 1974-03-07 | 1976-08-03 | Roemmers Sociedad Anonima Industrial, Comercial Y Financiera | Analgesic method containing Lysine 2-(2-methyl-3-chloro-anilino)-3-nicotinate |
US4332792A (en) * | 1980-07-14 | 1982-06-01 | Zoecon Corporation | Insect attractant |
WO1991007188A1 (en) * | 1989-11-22 | 1991-05-30 | Adrian Barbul | Method for reducing blood cholesterol using arginine |
US5157022A (en) * | 1989-11-22 | 1992-10-20 | Adrian Barbul | Method for reducing blood cholesterol using arginine |
JP2021525279A (en) * | 2018-05-22 | 2021-09-24 | ジャンプスタート ファーティリティ ピーティーワイ リミテッド | Amino acid salt of nicotinic acid riboside as an anti-aging agent |
Also Published As
Publication number | Publication date |
---|---|
BE606636A (en) | 1961-11-16 |
FR84M (en) | 1961-01-09 |
CH394199A (en) | 1965-06-30 |
ES269440A1 (en) | 1962-01-01 |
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