GB9117140D0 - Treatment of periodontitis - Google Patents

Treatment of periodontitis

Info

Publication number
GB9117140D0
GB9117140D0 GB919117140A GB9117140A GB9117140D0 GB 9117140 D0 GB9117140 D0 GB 9117140D0 GB 919117140 A GB919117140 A GB 919117140A GB 9117140 A GB9117140 A GB 9117140A GB 9117140 D0 GB9117140 D0 GB 9117140D0
Authority
GB
United Kingdom
Prior art keywords
periodontitis
prostaglandins
medicament
treatment
loss
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
GB919117140A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Unilever PLC
Original Assignee
Unilever PLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Unilever PLC filed Critical Unilever PLC
Priority to GB919117140A priority Critical patent/GB9117140D0/en
Publication of GB9117140D0 publication Critical patent/GB9117140D0/en
Priority to EP92202287A priority patent/EP0528468B1/en
Priority to DE69209190T priority patent/DE69209190T2/en
Priority to AT92202287T priority patent/ATE135569T1/en
Priority to US07/926,073 priority patent/US5240696A/en
Priority to AU20815/92A priority patent/AU2081592A/en
Priority to JP4210371A priority patent/JPH05194203A/en
Priority to CA002075551A priority patent/CA2075551C/en
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/075—Ethers or acetals
    • A61K31/085—Ethers or acetals having an ether linkage to aromatic ring nuclear carbon
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • A61K8/27—Zinc; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34—Alcohols
    • A61K8/347—Phenols
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/36—Carboxylic acids; Salts or anhydrides thereof
    • A61K8/365—Hydroxycarboxylic acids; Ketocarboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/74—Biological properties of particular ingredients
    • A61K2800/78—Enzyme modulators, e.g. Enzyme agonists
    • A61K2800/782—Enzyme inhibitors; Enzyme antagonists

Abstract

The present invention relates to the prevention of periodontitis by the use of a medicament which contains Triclosan. It has been found that Triclosan has a considerable anti-cyclo-oxygenase activity, thus inhibiting the formation of prostaglandins which are mediators of the loss of alveolar bone in the periodontium. Reducing the formation of said prostaglandins therefore reduces said loss of alveolar bone, which is one of the symptoms connected with periodontitis. The medicament is preferably in the form of a toothpaste.
GB919117140A 1991-08-08 1991-08-08 Treatment of periodontitis Pending GB9117140D0 (en)

Priority Applications (8)

Application Number Priority Date Filing Date Title
GB919117140A GB9117140D0 (en) 1991-08-08 1991-08-08 Treatment of periodontitis
EP92202287A EP0528468B1 (en) 1991-08-08 1992-07-24 Use of triclosan for the manufacture of a medicament for inhibiting cyclooxygenase
DE69209190T DE69209190T2 (en) 1991-08-08 1992-07-24 Use of triclosan in the manufacture of a medicament for inhibiting cyclooxygenase
AT92202287T ATE135569T1 (en) 1991-08-08 1992-07-24 USE OF TRICLOSAN FOR PRODUCING A DRUG FOR INHIBITING CYCLOOXYGENASE
US07/926,073 US5240696A (en) 1991-08-08 1992-08-05 Treatment of periodontitis
AU20815/92A AU2081592A (en) 1991-08-08 1992-08-05 Treatment of periodontitus
JP4210371A JPH05194203A (en) 1991-08-08 1992-08-06 Remedy of periodontitis
CA002075551A CA2075551C (en) 1991-08-08 1992-08-07 Treatment of periodontitis

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB919117140A GB9117140D0 (en) 1991-08-08 1991-08-08 Treatment of periodontitis

Publications (1)

Publication Number Publication Date
GB9117140D0 true GB9117140D0 (en) 1991-09-25

Family

ID=10699703

Family Applications (1)

Application Number Title Priority Date Filing Date
GB919117140A Pending GB9117140D0 (en) 1991-08-08 1991-08-08 Treatment of periodontitis

Country Status (8)

Country Link
US (1) US5240696A (en)
EP (1) EP0528468B1 (en)
JP (1) JPH05194203A (en)
AT (1) ATE135569T1 (en)
AU (1) AU2081592A (en)
CA (1) CA2075551C (en)
DE (1) DE69209190T2 (en)
GB (1) GB9117140D0 (en)

Families Citing this family (38)

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JP2979446B2 (en) * 1991-11-06 1999-11-15 ライオン株式会社 Oral composition
US6440395B1 (en) 1992-06-22 2002-08-27 Barry M. Libin Antiplaque mouth rinse
AU6721494A (en) * 1993-05-13 1994-12-12 Unilever Plc Oral compositions containing triclosan for the treatment of aphthous ulcers
US5843409A (en) * 1994-08-08 1998-12-01 Colgate Palmolive Company Two component dentifrice for the treatment of dentinal hypersensitivity
US5807541A (en) * 1996-04-22 1998-09-15 Sepracor, Inc. NSAID/fluoride periodontal compositions and methods
US5958911A (en) * 1996-11-05 1999-09-28 The Research Foundation Of State University Of New York Method of relieving inflammation by using 5-alkylsulfonylsalicylanilides
US5932192A (en) * 1997-04-23 1999-08-03 Colgate-Palmolive Company Lower astringent two component stannous and potassium salt containing dentifrice
ID20480A (en) * 1997-10-02 1998-12-24 Lg Chemical Ltd COMPOSITION TO PREVENT OR TREAT PERIODONTAL DISEASE CONSIST OF EXTRACT FROM ACHYRANTHIS RADIX OR ULMUS CORTEX
US6117859A (en) * 1997-11-04 2000-09-12 The Research Foundation Of State University Of New York Method of relieving chronic inflammation by using 5-alkylsulfonylsalicylanilides
US5998487A (en) * 1998-04-08 1999-12-07 Colgate-Palmolive Company Anti-inflammatory and antibacterial benzyl phenol agents and their use in oral compositions
DE19834355A1 (en) * 1998-07-30 2000-02-03 Henkel Kgaa Anti-inflammatory dentifrices
US5945089A (en) * 1998-11-05 1999-08-31 I-Dent International Corporation Method of treating mucositis
EP0992238B1 (en) * 1998-10-06 2004-10-13 I-Dent International Corporation Use of triclosan for preventing and treating mucositis
AU2080700A (en) * 1999-03-12 2000-09-14 Pfizer Products Inc. Compositions comprising a potassium salt active ingredient, including oral compositions for reducing dental nerve and dentin sensitivity comprising a non-menthol flavoring
AU4746600A (en) * 1999-04-19 2000-11-02 Bernard, Laurence M. C. Oral care composition
FR2812192B1 (en) * 2000-07-28 2003-01-31 Oreal USE OF PROSTAGLANDIN EP-3 RECEPTOR ANTAGONISTS AS A COSMETIC AGENT FOR MITIGATING, REDUCING OR STOPPING HAIR AND HAIR LOSS
FR2812190B1 (en) * 2000-07-28 2003-01-31 Oreal USE OF NON-PROSTANOIC AGONISTS OF EP-2 AND / OR EP-4 PROSTAGLANDIN RECEPTORS AS A COSMETIC AGENT FOR MITIGATING, DECREASING OR STOPPING HAIR AND HAIR LOSS
TW200403072A (en) * 2002-01-23 2004-03-01 Upjohn Co Combination therapy for the treatment of bacterial infections
ES2214135B1 (en) * 2003-02-21 2005-05-01 Laboratorios Kin S.A. COMPOSITION FOR THE TREATMENT OF ORAL CAVITY AND CORRESPONDING USE.
GB0319566D0 (en) * 2003-08-20 2003-09-24 Unilever Plc Use of oral care composition
US20060134025A1 (en) * 2004-12-17 2006-06-22 Colgate-Palmolive Company Oral compositions containing extracts of Rosmarinus and related methods
US20060141017A1 (en) * 2004-12-23 2006-06-29 Kling William O Zinc-based compositions and methods of use
CN104127399A (en) * 2005-12-21 2014-11-05 高露洁-棕榄公司 Improved oral compositions comprising zinc citrate and/or tocopherol agents
WO2007082181A2 (en) 2006-01-10 2007-07-19 Colgate-Palmolive Company Methods of modulating cell surface receptors to prevent or reduce inflammation
US7687650B2 (en) 2006-02-03 2010-03-30 Jr Chem, Llc Chemical compositions and methods of making them
US7897800B2 (en) 2006-02-03 2011-03-01 Jr Chem, Llc Chemical compositions and methods of making them
CA2641420C (en) 2006-02-03 2013-06-25 Jr Chem, Llc Anti-aging treatment using copper and zinc compositions
US7867522B2 (en) 2006-09-28 2011-01-11 Jr Chem, Llc Method of wound/burn healing using copper-zinc compositions
US8273791B2 (en) 2008-01-04 2012-09-25 Jr Chem, Llc Compositions, kits and regimens for the treatment of skin, especially décolletage
US20160184354A1 (en) 2009-01-23 2016-06-30 Jr Chem, Llc Rosacea treatments and kits for performing them
CA2753658C (en) 2009-04-01 2014-10-28 Colgate-Palmolive Company Anti-biofilm carbonate compounds for use in oral care compositions
TWI481870B (en) 2009-04-01 2015-04-21 Colgate Palmolive Co Protein biomarkers for soft tissue disease diagnosis and as therapeutic targets for oral care intervention
TWI405565B (en) 2009-04-01 2013-08-21 Colgate Palmolive Co Anti bone-loss and anti attachment-loss effects of an oral composition
RU2492857C2 (en) 2009-04-01 2013-09-20 Колгейт-Палмолив Компани Menthol derivative compounds and using them as active systemic agents and oral agents
US9968803B2 (en) 2009-10-29 2018-05-15 Colgate-Palmolive Company Low water stannous fluoride plus zinc citrate dentifrice with improved stability, rheology, and efficacy
US8952057B2 (en) 2011-01-11 2015-02-10 Jr Chem, Llc Compositions for anorectal use and methods for treating anorectal disorders
EP2921173A1 (en) * 2014-03-21 2015-09-23 Omya International AG Surface-reacted calcium carbonate for desensitizing teeth
JP7412869B2 (en) * 2016-08-05 2024-01-15 小林製薬株式会社 Gum care agent and oral composition for gum care containing the same

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JPS5238030A (en) * 1975-07-04 1977-03-24 Gaba Ag Mouth and tooth reparing agent
US4287191A (en) * 1980-04-14 1981-09-01 The Research Foundation Of State University Of New York Novel salicylanilides and microbiocidal compositions and uses thereof
US4358443A (en) * 1980-04-14 1982-11-09 The Research Foundation Of State University Of New York Method and composition for controlling the growth of microorganisms
GB2084870B (en) * 1980-10-10 1985-05-09 Muhlemann R Hans Oral compositions containing pyrimidine amine compounds and zinc salts
US4742083A (en) * 1983-08-24 1988-05-03 Lever Brothers Company Method of relieving pain and inflammatory conditions employing substituted salicylamides
GB8411731D0 (en) * 1984-05-09 1984-06-13 Unilever Plc Oral compositions
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US4664906A (en) * 1984-08-30 1987-05-12 Johnson & Johnson Products Inc. Oral compositions
US5225441A (en) * 1987-06-18 1993-07-06 Block Drug Company, Inc. Treatment of periodontal disease
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GB9107833D0 (en) * 1991-04-12 1991-05-29 Unilever Plc Treatment of periodontitis

Also Published As

Publication number Publication date
DE69209190T2 (en) 1996-08-08
AU2081592A (en) 1993-02-11
DE69209190D1 (en) 1996-04-25
EP0528468A1 (en) 1993-02-24
JPH05194203A (en) 1993-08-03
CA2075551A1 (en) 1993-02-09
EP0528468B1 (en) 1996-03-20
CA2075551C (en) 1996-05-07
ATE135569T1 (en) 1996-04-15
US5240696A (en) 1993-08-31

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